Lukas A Huber

Author PubWeight™ 69.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the next 10 years of proteomics. Proteomics 2006 3.61
2 Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction. Dev Cell 2002 2.98
3 A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14. Nat Med 2006 2.85
4 MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity. Nat Genet 2008 2.24
5 Erythropoietin contrastingly affects bacterial infection and experimental colitis by inhibiting nuclear factor-κB-inducible immune pathways. Immunity 2011 2.20
6 Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia 2005 2.18
7 Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae. Dev Cell 2010 2.17
8 p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis. J Cell Biol 2006 2.15
9 Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease. Nature 2009 2.05
10 Comm sorts robo to control axon guidance at the Drosophila midline. Cell 2002 1.98
11 The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis. Blood 2013 1.54
12 Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes. Proc Natl Acad Sci U S A 2004 1.43
13 Identification of vaccine candidate antigens of Staphylococcus aureus by serological proteome analysis. Proteomics 2002 1.27
14 Quantitative proteomics and phosphoproteomics reveal novel insights into complexity and dynamics of the EGFR signaling network. Proteomics 2008 1.27
15 Phosphoproteomics strategies for the functional analysis of signal transduction. Proteomics 2006 1.26
16 Loss-of-function of MYO5B is the main cause of microvillus inclusion disease: 15 novel mutations and a CaCo-2 RNAi cell model. Hum Mutat 2010 1.20
17 Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers. Oncogene 2002 1.08
18 TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells. EMBO J 2002 1.07
19 Zooming in: fractionation strategies in proteomics. Proteomics 2004 1.06
20 Biomarker discovery in breast cancer serum using 2-D differential gel electrophoresis/ MALDI-TOF/TOF and data validation by routine clinical assays. Electrophoresis 2006 1.06
21 Phosphorylation-regulated cleavage of the reticulon protein Nogo-B by caspase-7 at a noncanonical recognition site. Proteomics 2007 1.04
22 Intracellular signaling pathways regulating radioresistance of human prostate carcinoma cells. Proteomics 2008 1.03
23 Enrichment of low-abundant serum proteins by albumin/immunoglobulin G immunoaffinity depletion under partly denaturing conditions. Electrophoresis 2005 1.01
24 Muscle regeneration and myogenic differentiation defects in mice lacking TIS7. Mol Cell Biol 2004 0.99
25 Epithelial-to-mesenchymal transition and c-myc expression are the determinants of cetuximab-induced enhancement of squamous cell carcinoma radioresponse. Radiother Oncol 2010 0.99
26 Identification of endosomal epidermal growth factor receptor signaling targets by functional organelle proteomics. Mol Cell Proteomics 2007 0.98
27 Microvillus inclusion disease: loss of Myosin vb disrupts intracellular traffic and cell polarity. Traffic 2013 0.98
28 Role of TIS7 family of transcriptional regulators in differentiation and regeneration. Differentiation 2007 0.95
29 Apoptosis resistance of senescent human fibroblasts is correlated with the absence of nuclear IGFBP-3. Aging Cell 2005 0.94
30 QIKS--Quantitative identification of kinase substrates. Proteomics 2010 0.91
31 Identification of novel ribonucleo-protein complexes from the brain-specific snoRNA MBII-52. RNA 2010 0.91
32 Reassessing the role of phosphocaveolin-1 in cell adhesion and migration. Traffic 2007 0.90
33 A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation. J Exp Med 2011 0.89
34 The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection. J Cell Sci 2012 0.87
35 Quantitative detection of phosphoproteins by combination of two-dimensional difference gel electrophoresis and phosphospecific fluorescent staining. Electrophoresis 2005 0.87
36 Endosomal signaling and cell migration. Curr Opin Cell Biol 2011 0.86
37 Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts. Proteomics 2010 0.85
38 Stability of the endosomal scaffold protein LAMTOR3 depends on heterodimer assembly and proteasomal degradation. J Biol Chem 2013 0.85
39 TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent. J Biol Chem 2005 0.85
40 Mapping in vivo signal transduction defects by phosphoproteomics. Trends Mol Med 2011 0.84
41 Deletion of Tis7 protects mice from high-fat diet-induced weight gain and blunts the intestinal adaptive response postresection. J Nutr 2010 0.84
42 Antitumor activity of CTFB, a novel anticancer agent, is associated with the down-regulation of nuclear factor-kappaB expression and proteasome activation in head and neck squamous carcinoma cell lines. Mol Cancer Ther 2007 0.84
43 Induction of short interspersed nuclear repeat-containing transcripts in epithelial cells upon infection with a chicken adenovirus. J Mol Biol 2003 0.82
44 Localization of Rab proteins to peroxisomes: a proteomics and immunofluorescence study. FEBS Lett 2013 0.81
45 Insulin-like growth factor-binding protein-5 enters vesicular structures but not the nucleus. Traffic 2007 0.81
46 Identification and dynamics of proteins adhering to the surface of medical silicones in vivo and in vitro. J Proteome Res 2007 0.81
47 The transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expression. Eur J Neurosci 2007 0.81
48 Progress in capillary electrophoresis coupled to matrix-assisted laser desorption/ionization - time of flight mass spectrometry. Electrophoresis 2006 0.80
49 Analysis of protein phosphorylation by monolithic extraction columns based on poly(divinylbenzene) containing embedded titanium dioxide and zirconium dioxide nano-powders. Proteomics 2008 0.80
50 Comprehensive proteomic and transcriptomic characterization of hepatic expression signatures affected in p14 liver conditional knockout mice. Proteomics 2011 0.80
51 Simultaneous analysis of multiple serum proteins adhering to the surface of medical grade polydimethylsiloxane elastomers. J Immunol Methods 2007 0.79
52 Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk. PLoS One 2013 0.79
53 Analysis of the cellular uptake and nuclear delivery of insulin-like growth factor binding protein-3 in human osteosarcoma cells. Int J Cancer 2011 0.78
54 Poly(glycidyl methacrylate/divinylbenzene)-IDA-FeIII in phosphoproteomics. J Proteome Res 2005 0.78
55 Ultra-fast mass fingerprinting by high-affinity capture of peptides and proteins on derivatized poly(glycidyl methacrylate/divinylbenzene) for the analysis of serum and cell lysates. Rapid Commun Mass Spectrom 2006 0.78
56 Phosphoproteomic analysis using immobilized metal ion affinity chromatography on the basis of cellulose powder. Proteomics 2005 0.77
57 Quantitative measurement of cell migration using time-lapse videomicroscopy and non-linear system analysis. Histochem Cell Biol 2003 0.77
58 Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression. Breast Cancer Res 2014 0.77
59 Microscopy of the Drosophila facet eye: vademecum for standardized fixation, embedding, and sectioning. Microsc Res Tech 2006 0.76
60 C60-fullerene bound silica for the preconcentration and the fractionation of multiphosphorylated peptides. Anal Chim Acta 2012 0.75
61 Do pharmacogenetics, genomics and epigenetics hold promise for molecular therapeutics and health? Curr Opin Mol Ther 2010 0.75
62 Screening for MAPK modulators using an in-cell western assay. Methods Mol Biol 2014 0.75
63 A new type of metal chelate affinity chromatography using trivalent lanthanide ions for phosphopeptide enrichment. Analyst 2013 0.75
64 Signal transduction proteomics. Proteomics 2008 0.75