Published in Mol Biosyst on January 31, 2011
Aminonaphthalene 2-cyanoacrylate (ANCA) probes fluorescently discriminate between amyloid-β and prion plaques in brain. J Am Chem Soc (2012) 0.87
Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts. Chemistry (2014) 0.85
Measurement of amyloid formation by turbidity assay-seeing through the cloud. Biophys Rev (2016) 0.81
Computational modeling of the relationship between amyloid and disease. Biophys Rev (2012) 0.79
A flash in the pan: dissecting dynamic amyloid intermediates using fluorescence. FEBS Lett (2013) 0.78
Dual Functional Small Molecule Probes as Fluorophore and Ligand for Misfolding Proteins. Curr Org Chem (2013) 0.77
Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence. J Mol Biol (2016) 0.75
Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes. Sci Rep (2015) 0.75
Probing amylin fibrillation at an early stage via a tetracysteine-recognising fluorophore. Talanta (2017) 0.75
Amyloid beta: structure, biology and structure-based therapeutic development. Acta Pharmacol Sin (2017) 0.75
Stepwise unfolding of human β2-microglobulin into a disordered amyloidogenic precursor at low pH. Eur Biophys J (2016) 0.75
The biological and chemical basis for tissue-selective amyloid disease. Cell (2005) 2.76
Prion strain discrimination using luminescent conjugated polymers. Nat Methods (2007) 2.62
Imaging distinct conformational states of amyloid-beta fibrils in Alzheimer's disease using novel luminescent probes. ACS Chem Biol (2007) 2.18
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation. J Clin Invest (2008) 1.59
Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. ACS Chem Biol (2009) 1.42
Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy. Biophys J (2005) 1.36
Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice. EMBO Rep (2013) 1.20
Energetic characteristics of the new transthyretin variant A25T may explain its atypical central nervous system pathology. Lab Invest (2003) 1.10
Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates. Org Biomol Chem (2011) 1.08
Lysozyme amyloidogenesis is accelerated by specific nicking and fragmentation but decelerated by intact protein binding and conversion. J Mol Biol (2006) 1.08
Conjugated polyelectrolytes--conformation-sensitive optical probes for staining and characterization of amyloid deposits. Chembiochem (2006) 1.07
Conjugated polyelectrolytes: conformation-sensitive optical probes for detection of amyloid fibril formation. Biochemistry (2005) 1.05
Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis. J Mol Biol (2005) 1.04
Studies of luminescent conjugated polythiophene derivatives: enhanced spectral discrimination of protein conformational states. Bioconjug Chem (2007) 1.03
Aβ seeds resist inactivation by formaldehyde. Acta Neuropathol (2014) 1.03
A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice. Neurobiol Aging (2008) 1.02
Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila. PLoS One (2012) 1.01
Prefibrillar transthyretin oligomers and cold stored native tetrameric transthyretin are cytotoxic in cell culture. Biochem Biophys Res Commun (2008) 1.01
Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states. FEBS J (2010) 0.99
Native, amyloid fibrils and beta-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly. Mol Immunol (2008) 0.95
Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses. Nat Protoc (2010) 0.93
Unfolding a folding disease: folding, misfolding and aggregation of the marble brain syndrome-associated mutant H107Y of human carbonic anhydrase II. J Mol Biol (2004) 0.92
Amyloid fibrils of human prion protein are spun and woven from morphologically disordered aggregates. Prion (2009) 0.92
Evidence for age-dependent in vivo conformational rearrangement within Aβ amyloid deposits. ACS Chem Biol (2013) 0.92
Spectral discrimination of cerebral amyloid lesions after peripheral application of luminescent conjugated oligothiophenes. Am J Pathol (2012) 0.91
Synthesis of a regioregular zwitterionic conjugated oligoelectrolyte, usable as an optical probe for detection of amyloid fibril formation at acidic pH. J Am Chem Soc (2005) 0.91
Conformational rearrangements of tail-less complex polypeptide 1 (TCP-1) ring complex (TRiC)-bound actin. Biochemistry (2007) 0.89
Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands. Prion (2014) 0.88
Domain-specific chaperone-induced expansion is required for beta-actin folding: a comparison of beta-actin conformations upon interactions with GroEL and tail-less complex polypeptide 1 ring complex (TRiC). Biochemistry (2007) 0.87
Modeling familial amyloidotic polyneuropathy (Transthyretin V30M) in Drosophila melanogaster. Neurodegener Dis (2009) 0.87
Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease. Am J Pathol (2011) 0.86
Multiple substitutions of methionine 129 in human prion protein reveal its importance in the amyloid fibrillation pathway. J Biol Chem (2012) 0.85
Localization of cholesterol, amyloid and glia in Alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging. Acta Neuropathol (2012) 0.85
Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates. J Biol Chem (2012) 0.85
A pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections. Methods Mol Biol (2012) 0.81
The cyclooxygenase-2 inhibitor celecoxib is a potent inhibitor of human carbonic anhydrase II. Inflammation (2004) 0.81
Protein folding, misfolding and disease. FEBS Lett (2009) 0.80
Amyloid beta(1-40)-induced astrogliosis and the effect of genistein treatment in rat: a three-dimensional confocal morphometric and proteomic study. PLoS One (2013) 0.80
Nanoscopic and photonic ultrastructural characterization of two distinct insulin amyloid states. Int J Mol Sci (2012) 0.79
A nonessential role for Arg 55 in cyclophilin18 for catalysis of proline isomerization during protein folding. Protein Sci (2009) 0.79
Activity, folding, misfolding, and aggregation in vitro of the naturally occurring human tissue factor mutant R200W. Biochemistry (2005) 0.79
Sensitive and rapid assessment of amyloid by oligothiophene fluorescence in subcutaneous fat tissue. Amyloid (2014) 0.78
Is the prevalent human prion protein 129M/V mutation a living fossil from a Paleolithic panzootic superprion pandemic? Prion (2014) 0.78
Power tools for Alzheimer's disease - an electrochemical preamp for Aβ. J Neurochem (2012) 0.78
Chaperone activity of Cyp18 through hydrophobic condensation that enables rescue of transient misfolded molten globule intermediates. Biochemistry (2010) 0.77
GroEL-induced topological dislocation of a substrate protein β-sheet core: a solution EPR spin-spin distance study. J Chem Biol (2010) 0.76
Cell interaction study of amyloid by using luminescent conjugated polythiophene: implication that amyloid cytotoxicity is correlated with prolonged cellular binding. Chembiochem (2012) 0.76
Thermodynamic stability and denaturation kinetics of a benign natural transthyretin mutant identified in a Danish kindred. Amyloid (2011) 0.76
Thermodynamic interrogation of a folding disease. Mutant mapping of position 107 in human carbonic anhydrase II linked to marble brain disease. Biochemistry (2008) 0.76
Reshaping the folding energy landscape by chloride salt: impact on molten-globule formation and aggregation behavior of carbonic anhydrase. FEBS Lett (2004) 0.75
Enhanced fluorescent assignment of protein aggregates by an oligothiophene-porphyrin-based amyloid ligand. Macromol Rapid Commun (2013) 0.75
Small-molecule suppression of misfolding of mutated human carbonic anhydrase II linked to marble brain disease. Biochemistry (2009) 0.75
Spatially controlled amyloid reactions using organic electronics. Small (2010) 0.75
Derivatization of a bioorthogonal protected trisaccharide linker-toward multimodal tools for chemical biology. Bioconjug Chem (2012) 0.75
Binding of polythiophenes to amyloids: structural mapping of the pharmacophore. ACS Chem Neurosci (2017) 0.75