Published in Am J Trop Med Hyg on February 01, 2011
Early invasion of brain parenchyma by African trypanosomes. PLoS One (2012) 0.92
Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis. PLoS Negl Trop Dis (2011) 0.92
Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier. Br J Pharmacol (2012) 0.87
Establishment of ATP-based luciferase viability assay in 96-well plate for Trypanosoma congolense. J Vet Med Sci (2014) 0.86
Late stage infection in sleeping sickness. PLoS One (2012) 0.85
Imaging African trypanosomes. Parasite Immunol (2013) 0.81
Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes. PLoS Negl Trop Dis (2015) 0.80
Imaging of small-animal models of infectious diseases. Am J Pathol (2012) 0.77
Trypanosoma brucei Invasion and T-Cell Infiltration of the Brain Parenchyma in Experimental Sleeping Sickness: Timing and Correlation with Functional Changes. PLoS Negl Trop Dis (2016) 0.75
Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis. Methods (2017) 0.75
The blood-brain barrier/neurovascular unit in health and disease. Pharmacol Rev (2005) 7.56
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat Immunol (2009) 5.97
The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis (2004) 5.49
Control and surveillance of African trypanosomiasis. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser (1998) 3.93
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature (2009) 3.33
Human African trypanosomiasis of the CNS: current issues and challenges. J Clin Invest (2004) 2.39
The continuing problem of human African trypanosomiasis (sleeping sickness). Ann Neurol (2008) 2.13
Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme. Acta Neuropathol (2003) 1.99
African trypanosome interactions with an in vitro model of the human blood-brain barrier. J Parasitol (2004) 1.27
Lethal African trypanosomiasis in a traveler: MRI and neuropathology. Neurology (2006) 1.27
Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease. J Clin Invest (2006) 1.24
Cerebral vessel laminins and IFN-gamma define Trypanosoma brucei brucei penetration of the blood-brain barrier. J Clin Invest (2004) 1.23
Spatially and genetically distinct African Trypanosome virulence variants defined by host interferon-gamma response. J Infect Dis (2007) 1.22
The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Curr Pharm Des (2008) 1.19
Trypanosoma brucei brucei crosses the blood-brain barrier while tight junction proteins are preserved in a rat chronic disease model. Neuropathol Appl Neurobiol (2001) 1.18
Meningoencephalitic African trypanosomiasis: Brain IL-10 and IL-6 are associated with protection from neuro-inflammatory pathology. J Neuroimmunol (2005) 1.15
Human African trypanosomiasis, chemotherapy and CNS disease. J Neuroimmunol (2009) 1.12
A substance P antagonist, RP-67,580, ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei. Proc Natl Acad Sci U S A (1997) 1.10
Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis. J Infect Dis (2009) 1.09
Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein. J Pharmacol Exp Ther (2009) 1.09
The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain. J Neurochem (2008) 1.07
Delivery of imaging agents into brain. Adv Drug Deliv Rev (1999) 1.07
Immunology: In the beginning. Nature (2009) 1.06
Human African trypanosomiasis (T.b. gambiense): a study of 16 fatal cases of sleeping sickness with some observations on acute reactive arsenical encephalopathy. Neuropathol Appl Neurobiol (1986) 1.04
Magnetic resonance imaging findings in human African trypanosomiasis: a four-year follow-up study in a patient and review of the literature. Am J Trop Med Hyg (2009) 1.03
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. Brain (2009) 1.02
Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice. Brain (2003) 1.02
MR imaging findings in African trypansomiasis. AJNR Am J Neuroradiol (2003) 0.97
The pathogenesis of trypanosomiasis of the CNS. Studies on parasitological and neurohistological findings in trypanosoma rhodesiense infected vervet monkeys. Virchows Arch A Pathol Anat Histopathol (1983) 0.95
Blood-brain barrier impairment with enhanced SP, NK-1R, GFAP and claudin-5 expressions in experimental cerebral toxocariasis. Parasite Immunol (2008) 0.93
Blood-brain barrier damage in experimental African trypanosomiasis. Ann Trop Med Parasitol (1994) 0.90
Meningoencephalitis in chronic Trypanosoma brucei rhodesiense infection of the white mouse. Tropenmed Parasitol (1979) 0.87
Trypanosomiasis and encephalitis: possible aetiology and treatment. Trans R Soc Trop Med Hyg (1990) 0.87
Quinolinic acid enhances permeability of rat brain microvessels to plasma albumin. Brain Res Bull (2000) 0.83
Human African trypanosomiasis: MRI. Neuroradiology (1997) 0.81
Trypanosoma brucei gambiense: cerebral immunopathology in mice. Acta Trop (1982) 0.77
Positive and negative effects of widespread badger culling on tuberculosis in cattle. Nature (2005) 6.64
Impact of localized badger culling on tuberculosis incidence in British cattle. Nature (2003) 4.84
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Preliminary report of principal results from a European multicenter study. J Cataract Refract Surg (2006) 3.42
Value based pricing for NHS drugs: an opportunity not to be missed? BMJ (2008) 3.33
Searching for a threshold, not setting one: the role of the National Institute for Health and Clinical Excellence. J Health Serv Res Policy (2007) 2.66
Culling and cattle controls influence tuberculosis risk for badgers. Proc Natl Acad Sci U S A (2006) 2.39
The neurotropic herpes viruses: herpes simplex and varicella-zoster. Lancet Neurol (2007) 2.37
ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: Case for a European multicenter study. J Cataract Refract Surg (2006) 2.15
Some inconsistencies in NICE's consideration of social values. Pharmacoeconomics (2014) 2.04
Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial. Int J Infect Dis (2007) 2.03
Randomized, controlled trial of insulin for acute poststroke hyperglycemia. Ann Neurol (2010) 1.90
Varicella-zoster virus gene 66 transcription and translation in latently infected human Ganglia. J Virol (2003) 1.80
An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer. Int J Colorectal Dis (2011) 1.44
Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. J Cereb Blood Flow Metab (2008) 1.35
Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. PLoS Biol (2013) 1.33
The efficacy of emamectin benzoate against infestations of Lepeophtheirus salmonis on farmed Atlantic salmon (Salmo salar L) in Scotland, 2002-2006. PLoS One (2008) 1.33
Bovine tuberculosis in cattle and badgers in localized culling areas. J Wildl Dis (2009) 1.30
Herpes simplex virus-1 and varicella-zoster virus latency in ganglia. J Neurovirol (2003) 1.30
Functional Magnetic Resonance Imaging (fMRI) reproducibility and variance components across visits and scanning sites with a finger tapping task. Neuroimage (2009) 1.29
Incorporation of uncertainty in health economic modelling studies. Pharmacoeconomics (2005) 1.27
Temporal, environmental and management factors influencing the epidemiological patterns of sea lice (Lepeophtheirus salmonis) infestations on farmed Atlantic salmon (Salmo salar) in Scotland. Pest Manag Sci (2002) 1.26
Simple model for tuberculosis in cattle and badgers. Proc Natl Acad Sci U S A (2005) 1.25
T2*-weighted magnetic resonance imaging with hyperoxia in acute ischemic stroke. Ann Neurol (2010) 1.24
Focus-specific clinical profiles in human African Trypanosomiasis caused by Trypanosoma brucei rhodesiense. PLoS Negl Trop Dis (2010) 1.23
Health technology funding decision-making processes around the world: the same, yet different. Pharmacoeconomics (2011) 1.23
Economic evaluation of genomic test-directed chemotherapy for early-stage lymph node-positive breast cancer. J Natl Cancer Inst (2011) 1.23
Spatially and genetically distinct African Trypanosome virulence variants defined by host interferon-gamma response. J Infect Dis (2007) 1.22
Bacillus Calmette-Guérin vaccination reduces the severity and progression of tuberculosis in badgers. Proc Biol Sci (2010) 1.19
Clinical observations associated with proven and unproven cases in the ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery. J Cataract Refract Surg (2009) 1.17
Meningoencephalitic African trypanosomiasis: Brain IL-10 and IL-6 are associated with protection from neuro-inflammatory pathology. J Neuroimmunol (2005) 1.15
Translation of varicella-zoster virus genes during human ganglionic latency. Virus Genes (2004) 1.15
Traversal of human and animal trypanosomes across the blood-brain barrier. J Neurovirol (2008) 1.11
Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. Validation using [14C]2-deoxyglucose autoradiography. J Cereb Blood Flow Metab (2011) 1.10
The parkinsonism-hyperpyrexia syndrome. Neurocrit Care (2008) 1.09
Assessing the convergence of Markov Chain Monte Carlo methods: an example from evaluation of diagnostic tests in absence of a gold standard. Prev Vet Med (2007) 1.07
The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain. J Neurochem (2008) 1.07
Zoster sine herpete: it would be rash to ignore it. Neurology (2011) 1.05
Social group size affects Mycobacterium bovis infection in European badgers (Meles meles). J Anim Ecol (2009) 1.05
Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. J Cereb Blood Flow Metab (2011) 1.04
Early and late HHV-6 gene transcripts in multiple sclerosis lesions and normal appearing white matter. Brain (2005) 1.03
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. Brain (2009) 1.02
Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice. Brain (2003) 1.02
In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis. PLoS Negl Trop Dis (2013) 1.02
Body-weight changes during growth in puppies of different breeds. J Nutr (2004) 0.99
Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats. J Cereb Blood Flow Metab (2013) 0.98
Noninvasive monitoring of chick development in ovo using a 7T MRI system from day 12 of incubation through to hatching. J Magn Reson Imaging (2007) 0.98
Key basic helix-loop-helix transcription factor genes Hes1 and Ngn2 are regulated by Pax3 during mouse embryonic development. Dev Biol (2008) 0.97
Prospective multi-centre Voxel Based Morphometry study employing scanner specific segmentations: procedure development using CaliBrain structural MRI data. BMC Med Imaging (2009) 0.96
BCG vaccination reduces risk of tuberculosis infection in vaccinated badgers and unvaccinated badger cubs. PLoS One (2012) 0.96
Is it time to revisit orphan drug policies? BMJ (2010) 0.96
Assessing the economic challenges posed by orphan drugs: a comment on Drummond et al. Int J Technol Assess Health Care (2007) 0.95
Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response. PLoS Negl Trop Dis (2012) 0.95
Cost-effectiveness of disease-modifying therapies in the management of multiple sclerosis for the Medicare population. Value Health (2011) 0.94
Varicella-Zoster virus proteins encoded by open reading frames 14 and 67 are both dispensable for the establishment of latency in a rat model. Virology (2004) 0.93
Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods. J Cereb Blood Flow Metab (2012) 0.93
Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis. PLoS Negl Trop Dis (2011) 0.92
To fund or not to fund: development of a decision-making framework for the coverage of new health technologies. Pharmacoeconomics (2011) 0.91
An attempt to investigate the presence of Epstein Barr virus in multiple sclerosis and normal control brain tissue. J Neurol (2007) 0.91
Value-based reimbursement decisions for orphan drugs: a scoping review and decision framework. Pharmacoeconomics (2015) 0.90
Weighting must wait: incorporating equity concerns into cost-effectiveness analysis may take longer than expected. Pharmacoeconomics (2009) 0.89
Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats. Stroke (2008) 0.89
Varicella-Zoster virus gene expression at variable periods following death in a rat model of ganglionic infection. Virus Genes (2006) 0.88
Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model. J Cereb Blood Flow Metab (2011) 0.88
Images in cardiovascular medicine. Noninvasive self-gated magnetic resonance cardiac imaging of developing chick embryos in ovo. Circulation (2008) 0.88
MRI safety review. Semin Ultrasound CT MR (2002) 0.87
Positive impact of pre-stroke surgery on survival following transient focal ischemia in hypertensive rats. J Neurosci Methods (2012) 0.87
An MRI-histological study of white matter in stroke-free SHRSP. J Cereb Blood Flow Metab (2013) 0.87
Assessment of the impact of the scanner-related factors on brain morphometry analysis with Brainvisa. BMC Med Imaging (2011) 0.86
Cost-effectiveness analysis and efficient use of the pharmaceutical budget: the key role of clinical pharmacologists. Br J Clin Pharmacol (2010) 0.86
Role of centralized review processes for making reimbursement decisions on new health technologies in Europe. Clinicoecon Outcomes Res (2011) 0.86
Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging. Int J Stroke (2014) 0.86
Magnetic resonance imaging technology in transtibial socket research: a pilot study. J Rehabil Res Dev (2007) 0.86
Localisation of regions of intense pleasure response evoked by soccer goals. Psychiatry Res (2008) 0.85
Endothelin and the ischaemic heart. Curr Vasc Pharmacol (2005) 0.85
Health economics in drug development: efficient research to inform healthcare funding decisions. Eur J Cancer (2010) 0.85
Updated cost-effectiveness analysis of trastuzumab for early breast cancer: a UK perspective considering duration of benefit, long-term toxicity and pattern of recurrence. Pharmacoeconomics (2011) 0.85
Human African trypanosomiasis: potential therapeutic benefits of an alternative suramin and melarsoprol regimen. Parasitol Int (2002) 0.84
Expected net present value of sample information: from burden to investment. Med Decis Making (2012) 0.84
Noninvasive MRI measurement of CBF: evaluating an arterial spin labelling sequence with 99mTc-HMPAO CBF autoradiography in a rat stroke model. J Cereb Blood Flow Metab (2012) 0.84
17beta-Estradiol treatment following permanent focal ischemia does not influence recovery of sensorimotor function. Neurobiol Dis (2006) 0.83
In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging. NMR Biomed (2009) 0.83
Evaluation of the translational and rotational forces acting on a highly ferromagnetic orthopedic spinal implant in magnetic resonance imaging. J Magn Reson Imaging (2009) 0.82
Subcellular localization of Mayven following expression of wild type and mutant EGFP tagged cDNAs. BMC Neurosci (2010) 0.82
Use of visual analog scales in economic evaluation. Expert Rev Pharmacoecon Outcomes Res (2003) 0.82
The incremental cost effectiveness of withdrawing pulmonary artery catheters from routine use in critical care. Appl Health Econ Health Policy (2005) 0.82