Published in Pharmacol Biochem Behav on February 02, 2011
Muscle sympathetic response to arousal predicts neurovascular reactivity during mental stress. J Physiol (2012) 0.89
Cholecystokinin knock-down in the basolateral amygdala has anxiolytic and antidepressant-like effects in mice. Neuroscience (2012) 0.79
Chemical composition and anxiolytic evaluation of Achillea Wilhelmsii C. Koch essential oil in rat. Res Pharm Sci (2013) 0.77
Effects of Xiaoyaosan on Stress-Induced Anxiety-Like Behavior in Rats: Involvement of CRF1 Receptor. Evid Based Complement Alternat Med (2016) 0.75
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J (2005) 3.23
S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulfide-mediated pathway. Am J Physiol Heart Circ Physiol (2007) 1.72
Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia. J Neurochem (2006) 1.61
Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Nat Prod Rep (2005) 1.51
Hydrogen sulfide is a mediator of cerebral ischemic damage. Stroke (2006) 1.46
Oxidative stress: apoptosis in neuronal injury. Curr Alzheimer Res (2006) 1.44
Hydrogen sulfide in the mammalian cardiovascular system. Antioxid Redox Signal (2012) 1.36
Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. Mol Pharmacol (2008) 1.29
Hydrogen sulfide: a novel signaling molecule in the central nervous system. Neurochem Int (2009) 1.23
Role of cystathionine γ-lyase/hydrogen sulfide pathway in cardiovascular disease: a novel therapeutic strategy? Antioxid Redox Signal (2012) 1.17
S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway. J Cardiovasc Pharmacol (2009) 1.13
Hydrogen sulphide regulates calcium homeostasis in microglial cells. Glia (2006) 1.09
H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S? PLoS One (2011) 1.05
Effects of purified herbal extract of Salvia miltiorrhiza on ischemic rat myocardium after acute myocardial infarction. Life Sci (2005) 1.05
S-propargyl-cysteine, a novel water-soluble modulator of endogenous hydrogen sulfide, promotes angiogenesis through activation of signal transducer and activator of transcription 3. Antioxid Redox Signal (2014) 1.02
Herba leonurine attenuates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells. Eur J Pharmacol (2009) 1.00
Hydrogen sulfide attenuates cardiac dysfunction in a rat model of heart failure: a mechanism through cardiac mitochondrial protection. Biosci Rep (2011) 1.00
Comparison of cardioprotective effects using ramipril and DanShen for the treatment of acute myocardial infarction in rats. Life Sci (2003) 0.96
Analysis of cardioprotective effects using purified Salvia miltiorrhiza extract on isolated rat hearts. J Pharmacol Sci (2006) 0.96
miRNA-30 family inhibition protects against cardiac ischemic injury by regulating cystathionine-γ-lyase expression. Antioxid Redox Signal (2014) 0.95
Leonurine protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function. Stroke (2010) 0.95
Cholecystokinin-2 (CCK2) receptor-mediated anxiety-like behaviors in rats. Neurosci Biobehav Rev (2005) 0.93
Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats. Neuroreport (2005) 0.93
Beta-cardiotoxin: a new three-finger toxin from Ophiophagus hannah (king cobra) venom with beta-blocker activity. FASEB J (2007) 0.92
Leonurine protects against tumor necrosis factor-α-mediated inflammation in human umbilical vein endothelial cells. Atherosclerosis (2011) 0.91
Cerebral protection of purified Herba Leonuri extract on middle cerebral artery occluded rats. J Ethnopharmacol (2009) 0.87
Cardioprotective effects of a novel hydrogen sulfide agent-controlled release formulation of S-propargyl-cysteine on heart failure rats and molecular mechanisms. PLoS One (2013) 0.87
Neuroprotective effects of leonurine on ischemia/reperfusion-induced mitochondrial dysfunctions in rat cerebral cortex. Biol Pharm Bull (2010) 0.87
Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax. J Cardiovasc Pharmacol (2008) 0.86
Impaired coupling of muscarinic M1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease. Neurobiol Aging (2005) 0.86
Antiapoptotic effect of novel compound from Herba leonuri - leonurine (SCM-198): a mechanism through inhibition of mitochondria dysfunction in H9c2 cells. Curr Pharm Biotechnol (2010) 0.85
Cardioprotective effects of nitric oxide-aspirin in myocardial ischemia-reperfused rats. Am J Physiol Heart Circ Physiol (2007) 0.85
Asymmetric synthesis and biological evaluation of Danshensu derivatives as anti-myocardial ischemia drug candidates. Bioorg Med Chem (2009) 0.84
Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease. Neurobiol Dis (2006) 0.84
Leonurine attenuates lipopolysaccharide-induced inflammatory responses in human endothelial cells: involvement of reactive oxygen species and NF-κB pathways. Eur J Pharmacol (2012) 0.83
Hydrogen sulfide protects SH-SY5Y neuronal cells against d-galactose induced cell injury by suppression of advanced glycation end products formation and oxidative stress. Neurochem Int (2012) 0.83
The synthesis and biological evaluation of novel Danshensu-cysteine analog conjugates as cardiovascular-protective agents. Eur J Med Chem (2012) 0.83
Upregulation of AMPA receptor GluR2 (GluA2) subunits in subcortical ischemic vascular dementia is repressed in the presence of Alzheimer's disease. Neurochem Int (2011) 0.83
Protective effects of novel single compound, Hirsutine on hypoxic neonatal rat cardiomyocytes. Eur J Pharmacol (2010) 0.82
High doses of simvastatin upregulate dopamine D1 and D2 receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase. Br J Pharmacol (2005) 0.82
Synthesis and biological evaluation of novel leonurine-SPRC conjugate as cardioprotective agents. Bioorg Med Chem Lett (2010) 0.82
Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One (2012) 0.82
Disrupted muscarinic M1 receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease. Neurobiol Aging (2006) 0.82
Brain 3-Mercaptopyruvate Sulfurtransferase (3MST): Cellular Localization and Downregulation after Acute Stroke. PLoS One (2013) 0.82
Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex. Neurochem Int (2010) 0.82
Therapeutic applications of organosulfur compounds as novel hydrogen sulfide donors and/or mediators. Expert Rev Clin Pharmacol (2011) 0.81
Neuroprotective effects of SCM198 on 6-hydroxydopamine-induced behavioral deficit in rats and cytotoxicity in neuronal SH-SY5Y cells. Neurochem Int (2010) 0.81
Anti-oxidative stress effects of Herba leonuri on ischemic rat hearts. Life Sci (2005) 0.80
Leonurine-cysteine analog conjugates as a new class of multifunctional anti-myocardial ischemia agent. Eur J Med Chem (2011) 0.80
S-propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuated tumor necrosis factor-α-induced inflammatory signaling and dysfunction in endothelial cells. Int J Cardiol (2012) 0.80
A serotoninergic basis for hyperphagic eating changes in Alzheimer's disease. J Neurol Sci (2009) 0.79
Alterations in NMDA receptor subunit densities and ligand binding to glycine recognition sites are associated with chronic anxiety in Alzheimer's disease. Neurobiol Aging (2007) 0.79
Differential involvement of hippocampal serotonin1A receptors and re-uptake sites in non-cognitive behaviors of Alzheimer's disease. Psychopharmacology (Berl) (2010) 0.79
Preservation of cortical histamine H3 receptors in ischemic vascular and mixed dementias. J Neurol Sci (2011) 0.78
Neuroprotective effect of Danshensu derivatives as anti-ischaemia agents on SH-SY5Y cells and rat brain. Biosci Rep (2013) 0.78
Andrographolide attenuates interleukin-1β-stimulated upregulation of chemokine CCL5 and glial fibrillary acidic protein in astrocytes. Neuroreport (2014) 0.77
Cholecystokinin-B receptor gene expression in cerebellum, pre-frontal cortex and cingulate gyrus and its association with suicide. Neurosci Lett (2004) 0.77
Serotonin transporters are preserved in the neocortex of anxious Alzheimer's disease patients. Neuroreport (2003) 0.76
Angiotensin receptor gene expression in candesartan mediated neuroprotection. Neuroreport (2004) 0.75
Effects of purified Salvia miltiorrhiza extract on cardiac vascular smooth muscle hypoxic cells. J Pharmacol Sci (2007) 0.75
Cyclooxygenase-1 inhibition shortens the duration of diazepam-induced loss of righting reflex in mice. Anesth Analg (2006) 0.75
Novel anti-diabetic effect of SCM-198 via inhibiting the hepatic NF-κB pathway in db/db mice. Biosci Rep (2012) 0.75
Effects of Leonurine on L-type calcium channel in rat ventricular myocytes. Biol Pharm Bull (2012) 0.75