Serum biomarker panels for the detection of pancreatic cancer.

PubWeight™: 1.98‹?› | Rank: Top 2%

🔗 View Article (PMC 3075824)

Published in Clin Cancer Res on February 15, 2011

Authors

Randall E Brand1, Brian M Nolen, Herbert J Zeh, Peter J Allen, Mohamad A Eloubeidi, Michael Goldberg, Eric Elton, Juan P Arnoletti, John D Christein, Selwyn M Vickers, Christopher J Langmead, Douglas P Landsittel, David C Whitcomb, William E Grizzle, Anna E Lokshin

Author Affiliations

1: Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Articles citing this

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature (2015) 5.15

MicroRNA array analysis finds elevated serum miR-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls. Clin Cancer Res (2013) 2.71

Clinicopathological characteristics in the differential diagnosis of hepatoid adenocarcinoma: a literature review. World J Gastroenterol (2013) 1.70

Prediagnostic serum biomarkers as early detection tools for pancreatic cancer in a large prospective cohort study. PLoS One (2014) 1.55

Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability. PLoS One (2014) 1.29

Markers of pancreatic cancer: working toward early detection. Clin Cancer Res (2011) 1.27

Early diagnosis of pancreatic cancer: challenges and new developments. Biomark Med (2012) 1.23

Multiplex targeted proteomic assay for biomarker detection in plasma: a pancreatic cancer biomarker case study. J Proteome Res (2012) 1.06

Advances in biomarker research for pancreatic cancer. Curr Pharm Des (2012) 1.05

Pancreatic ductal adenocarcinoma: risk factors, screening, and early detection. World J Gastroenterol (2014) 1.03

Validation of biomarkers that complement CA19.9 in detecting early pancreatic cancer. Clin Cancer Res (2014) 1.02

Immunosignature system for diagnosis of cancer. Proc Natl Acad Sci U S A (2014) 1.02

Advances in pancreatic cancer research: moving towards early detection. World J Gastroenterol (2014) 1.02

Immunosignaturing can detect products from molecular markers in brain cancer. PLoS One (2012) 1.01

Circulating RNAs as new biomarkers for detecting pancreatic cancer. World J Gastroenterol (2015) 1.01

iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance. Br J Cancer (2013) 0.99

Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinoma. BMC Cancer (2014) 0.99

Serum osteopontin and tissue inhibitor of metalloproteinase 1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma. Pancreas (2013) 0.98

Plasma metabolite biomarkers for the detection of pancreatic cancer. J Proteome Res (2014) 0.97

Strategies for discovering novel pancreatic cancer biomarkers. J Proteomics (2012) 0.96

Variable neuroendocrine-immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury. Brain Behav Immun (2014) 0.95

PAM4 enzyme immunoassay alone and in combination with CA 19-9 for the detection of pancreatic adenocarcinoma. Cancer (2012) 0.95

Glycomic and proteomic profiling of pancreatic cyst fluids identifies hyperfucosylated lactosamines on the N-linked glycans of overexpressed glycoproteins. Mol Cell Proteomics (2012) 0.94

Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals. J Transl Med (2013) 0.94

Serum dickkopf-1 is a novel serological biomarker for the diagnosis and prognosis of pancreatic cancer. Oncotarget (2015) 0.89

Sparse Proteomics Analysis - a compressed sensing-based approach for feature selection and classification of high-dimensional proteomics mass spectrometry data. BMC Bioinformatics (2017) 0.88

Urinary TIMP-1 and MMP-2 levels detect the presence of pancreatic malignancies. Br J Cancer (2014) 0.87

Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9. BMC Cancer (2013) 0.87

DJ-1, a novel biomarker and a selected target gene for overcoming chemoresistance in pancreatic cancer. J Cancer Res Clin Oncol (2012) 0.87

Biomarkers for pancreatic cancer: recent achievements in proteomics and genomics through classical and multivariate statistical methods. World J Gastroenterol (2014) 0.86

Polymorphisms of ICAM-1 are associated with gastric cancer risk and prognosis. World J Gastroenterol (2012) 0.86

Serum cytokine biomarker panels for discriminating pancreatic cancer from benign pancreatic disease. Mol Cancer (2014) 0.85

Molecular detection of pancreatic neoplasia: Current status and future promise. World J Gastroenterol (2015) 0.82

Prospects for developing an accurate diagnostic biomarker panel for low prevalence cancers. Theor Biol Med Model (2014) 0.82

Pancreatic carcinoma, pancreatitis, and healthy controls: metabolite models in a three-class diagnostic dilemma. Metabolomics (2012) 0.82

Tumor-associated Neutrophils and Malignant Progression in Intraductal Papillary Mucinous Neoplasms: An Opportunity for Identification of High-risk Disease. Ann Surg (2015) 0.80

-The advancement of biomarker-based diagnostic tools for ovarian, breast, and pancreatic cancer through the use of urine as an analytical biofluid. Int J Biol Markers (2011) 0.80

Biomarkers in pancreatic adenocarcinoma: current perspectives. Onco Targets Ther (2016) 0.79

Metabolomic profile in pancreatic cancer patients: a consensus-based approach to identify highly discriminating metabolites. Oncotarget (2016) 0.79

Cross-species antibody microarray interrogation identifies a 3-protein panel of plasma biomarkers for early diagnosis of pancreas cancer. Clin Cancer Res (2015) 0.79

A Multicenter Trial Defining a Serum Protein Signature Associated with Pancreatic Ductal Adenocarcinoma. Int J Proteomics (2015) 0.79

Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus. Clin Cancer Res (2015) 0.79

Non-invasive biomarkers in pancreatic cancer diagnosis: what we need versus what we have. Ann Transl Med (2016) 0.79

Biomarker validation: common data analysis concerns. Oncologist (2014) 0.79

ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells. Neoplasia (2013) 0.79

TIMPs: versatile extracellular regulators in cancer. Nat Rev Cancer (2016) 0.79

Improved Pancreatic Adenocarcinoma Diagnosis in Jaundiced and Non-Jaundiced Pancreatic Adenocarcinoma Patients through the Combination of Routine Clinical Markers Associated to Pancreatic Adenocarcinoma Pathophysiology. PLoS One (2016) 0.78

Surveillance for neoplasia in the pancreas. Best Pract Res Clin Gastroenterol (2016) 0.78

A comparative proteomic study of plasma in feline pancreatitis and pancreatic carcinoma using 2-dimensional gel electrophoresis to identify diagnostic biomarkers: A pilot study. Can J Vet Res (2015) 0.78

Precision diagnostics: moving towards protein biomarker signatures of clinical utility in cancer. Nat Rev Cancer (2017) 0.78

Differential expression and tumor necrosis factor-mediated regulation of TNFRSF11b/osteoprotegerin production by human melanomas. Pigment Cell Melanoma Res (2013) 0.77

Combining in Vitro Diagnostics with in Vivo Imaging for Earlier Detection of Pancreatic Ductal Adenocarcinoma: Challenges and Solutions. Radiology (2015) 0.76

Expression and diagnostic value of HE4 in pancreatic adenocarcinoma. Int J Mol Sci (2015) 0.76

A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study. Am J Gastroenterol (2016) 0.75

Comparative studies of TIMP-1 immunohistochemistry, TIMP-1 FISH analysis and plasma TIMP-1 in glioblastoma patients. J Neurooncol (2016) 0.75

Detection of Circulating Tumor Cells Using Negative Enrichment Immunofluorescence and an In Situ Hybridization System in Pancreatic Cancer. Int J Mol Sci (2017) 0.75

Current status of biomarker and targeted nanoparticle development: The precision oncology approach for pancreatic cancer therapy. Cancer Lett (2016) 0.75

Novel Diagnostic and Predictive Biomarkers in Pancreatic Adenocarcinoma. Int J Mol Sci (2017) 0.75

Accurate Quantification of Disease Markers in Human Serum Using Iron Oxide Nanoparticle-linked Immunosorbent Assay. Theranostics (2016) 0.75

Integration of binding peptide selection and multifunctional particles as tool-box for capture of soluble proteins in serum. J R Soc Interface (2014) 0.75

Novel biomarkers and endoscopic techniques for diagnosing pancreaticobiliary malignancy. F1000Res (2017) 0.75

Large-scale clinical validation of biomarkers for pancreatic cancer using a mass spectrometry-based proteomics approach. Oncotarget (2017) 0.75

Articles cited by this

Inflammation and cancer. Nature (2002) 53.78

ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. J Clin Oncol (2006) 7.43

Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin Cancer Res (2001) 4.19

Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer. Eur J Surg Oncol (2006) 3.24

New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancer. Lancet Oncol (2009) 2.92

Development of a multimarker assay for early detection of ovarian cancer. J Clin Oncol (2010) 2.71

The contribution of endogenous sources of DNA damage to the multiple mutations in cancer. Mutat Res (2001) 2.52

A mouse to human search for plasma proteome changes associated with pancreatic tumor development. PLoS Med (2008) 2.31

Epidemiology of pancreatic cancer. Minerva Chir (2004) 2.14

Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9. Clin Cancer Res (2006) 1.93

Early diagnosis of pancreatic cancer: neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neoplasia. Br J Cancer (2008) 1.93

Serum osteoprotegerin levels in healthy controls and cancer patients. Clin Cancer Res (2002) 1.88

Inflammation, microenvironment, and the immune system in cancer progression. Curr Pharm Des (2009) 1.79

Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma. Cancer Epidemiol Biomarkers Prev (2004) 1.76

Clinical significance of the measurements of serum matrix metalloproteinase-9 and its inhibitor (tissue inhibitor of metalloproteinase-1) in patients with pancreatic cancer: metalloproteinase-9 as an independent prognostic factor. Pancreas (2009) 1.62

Alcohol and smoking as risk factors in chronic pancreatitis and pancreatic cancer. Dig Dis Sci (1999) 1.59

Role of inflammation in pancreatic carcinogenesis and the implications for future therapy. Pancreatology (2005) 1.47

Acute-phase proteins or tumour markers: the role of SAA, SAP, CRP and CEA as indicators of metastasis in a broad spectrum of neoplastic diseases. Scand J Immunol (1984) 1.38

Identifying markers for pancreatic cancer by gene expression analysis. Cancer Epidemiol Biomarkers Prev (1998) 1.36

The matrix metalloproteinases and their inhibitors in the treatment of pancreatic cancer. Ann N Y Acad Sci (1999) 1.23

Acute-phase serum amyloid A stimulation of angiogenesis, leukocyte recruitment, and matrix degradation in rheumatoid arthritis through an NF-kappaB-dependent signal transduction pathway. Arthritis Rheum (2006) 1.15

Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors. Pancreatology (2008) 1.14

Changes in insulin resistance following bariatric surgery and the adipoinsular axis: role of the adipocytokines, leptin, adiponectin and resistin. Obes Surg (2005) 1.12

Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells. Int J Oncol (2003) 1.11

Expression of serum amyloid A, in normal, dysplastic, and neoplastic human colonic mucosa: implication for a role in colonic tumorigenesis. J Histochem Cytochem (2005) 1.10

Expression of intercellular adhesion molecule-1 in invasive breast cancer reflects low growth potential, negative lymph node involvement, and good prognosis. Clin Cancer Res (1998) 1.07

Screening for pancreatic cancer in high-risk individuals: a call for endoscopic ultrasound. Clin Cancer Res (2009) 1.03

TPS, CA 19-9, VEGF-A, and CEA as diagnostic and prognostic factors in patients with mass lesions in the pancreatic head. Ups J Med Sci (2008) 1.03

Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression. Cancer Biol Ther (2004) 1.02

Confounding effect of obstructive jaundice in the interpretation of proteomic plasma profiling data for pancreatic cancer. J Proteome Res (2009) 1.02

Tissue polypeptide specific antigen (TPS), a marker for differentiation between pancreatic carcinoma and chronic pancreatitis. A comparative study with CA 19-9. Cancer (2000) 1.01

Cancer of the pancreas: the best image for early detection--CT, MRI, PET or US? Can J Gastroenterol (2002) 0.99

The expression of adhesion molecules and the influence of inflammatory cytokines on the adhesion of human pancreatic carcinoma cells to mesothelial monolayers. Pancreas (2006) 0.96

Proteomics of pancreatic cancer. Pancreas (2008) 0.95

Comparison of circulating MMP-9, TIMP-1 and CA19-9 in the detection of pancreatic cancer. Anticancer Res (2010) 0.94

Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells. J Surg Res (1999) 0.92

Biological and therapeutic significance of tissue transglutaminase in pancreatic cancer. Amino Acids (2008) 0.89

Surgical palliation of pancreatic cancer. Adv Surg (2000) 0.86

Expression of tissue-type transglutaminase correlates positively with metastatic properties of human melanoma cell lines. Int J Cancer (1995) 0.85

Developments in serologic detection of human pancreatic adenocarcinoma. Scand J Gastroenterol (1999) 0.85

Expression of intercellular adhesion molecule (ICAM)-1 or ICAM-2 is critical in determining sensitivity of pancreatic cancer cells to cytolysis by human gammadelta-T cells: implications in the design of gammadelta-T-cell-based immunotherapies for pancreatic cancer. J Gastroenterol Hepatol (2008) 0.85

Serum evaluation of soluble interferon-alpha/beta receptor and high-sensitivity C-reactive protein for diagnosis of the patients with gastrointestinal and hepatobiliary-pancreatic cancer. Cytokine (2009) 0.84

Adjuvant radiotherapy in resectable pancreatic carcinoma. Eur J Surg Oncol (2002) 0.84

Transglutaminase activity in human colorectal carcinomas of differing metastatic potential. Cancer Lett (1991) 0.82

Potential value of soluble intercellular adhesion molecule-1 in the serum of patients with bladder cancer. Urol Int (2003) 0.82

Soluble intercellular adhesion molecule-1 as a prognostic marker for stage II colorectal cancer patients. Ann Surg Oncol (2008) 0.81

Imaging techniques in the evaluation of adenocarcinoma of the pancreas. Dig Dis (1998) 0.80

Screening for familial pancreatic cancer: is doing something better than doing nothing? Gut (2009) 0.79

Articles by these authors

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med (2014) 8.36

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat Biotechnol (2008) 6.81

Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation. Ann Surg (2012) 5.55

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. Sci Transl Med (2011) 5.03

Endogenous HMGB1 regulates autophagy. J Cell Biol (2010) 4.71

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation. Nature (2011) 4.60

Equal efficacy of endoscopic and surgical cystogastrostomy for pancreatic pseudocyst drainage in a randomized trial. Gastroenterology (2013) 4.52

Robot-assisted minimally invasive distal pancreatectomy is superior to the laparoscopic technique. Ann Surg (2013) 3.94

Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis. Am J Gastroenterol (2009) 3.88

Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility. Clin Chem (2005) 3.71

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Proc Natl Acad Sci U S A (2011) 3.51

IAP Guidelines for the Surgical Management of Acute Pancreatitis. Pancreatology (2002) 3.48

Role of EUS in drainage of peripancreatic fluid collections not amenable for endoscopic transmural drainage. Gastrointest Endosc (2007) 3.40

Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties. PLoS One (2008) 3.36

MIFlowCyt: the minimum information about a Flow Cytometry Experiment. Cytometry A (2008) 3.33

The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. Immunol Rev (2007) 3.33

Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens. Cancer Prev Res (Phila) (2011) 3.33

Relationship among hospital ERCP volume, length of stay, and technical outcomes. Gastrointest Endosc (2006) 3.30

Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function. J Immunol (2006) 3.12

High-mobility group box 1 and cancer. Biochim Biophys Acta (2010) 3.11

A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer. Cancer Prev Res (Phila) (2011) 3.03

Electronic synoptic operative reporting: assessing the reliability and completeness of synoptic reports for pancreatic resection. J Am Coll Surg (2010) 2.98

SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Res (2007) 2.98

Return of research results from genomic biobanks: cost matters. Genet Med (2012) 2.93

Multiplexed immunobead-based cytokine profiling for early detection of ovarian cancer. Cancer Epidemiol Biomarkers Prev (2005) 2.90

Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol Hepatol (2004) 2.82

MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med (2008) 2.79

Development of a multimarker assay for early detection of ovarian cancer. J Clin Oncol (2010) 2.71

Yield of EUS-guided FNA of pancreatic masses in the presence or the absence of chronic pancreatitis. Gastrointest Endosc (2005) 2.69

Modern age pathology of pulmonary arterial hypertension. Am J Respir Crit Care Med (2012) 2.68

Induction of myeloid-derived suppressor cells by tumor exosomes. Int J Cancer (2009) 2.64

Prospective randomized trial comparing EUS and EGD for transmural drainage of pancreatic pseudocysts (with videos). Gastrointest Endosc (2008) 2.61

RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation. J Transl Med (2009) 2.56

Antibiotic prophylaxis for GI endoscopy. Gastrointest Endosc (2014) 2.52

Diagnosis of gastrointestinal tract lesions by endoscopic ultrasound-guided fine-needle aspiration biopsy. Cancer (2004) 2.46

Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis. Clin Gastroenterol Hepatol (2010) 2.46

Blood urea nitrogen in the early assessment of acute pancreatitis: an international validation study. Arch Intern Med (2011) 2.46

Feasibility and yield of screening in relatives from familial pancreatic cancer families. Am J Gastroenterol (2011) 2.42

Masquerader: high mobility group box-1 and cancer. Clin Cancer Res (2007) 2.40

Development of lipidoid-siRNA formulations for systemic delivery to the liver. Mol Ther (2009) 2.39

SELDI-TOF MS whole serum proteomic profiling with IMAC surface does not reliably detect prostate cancer. Clin Chem (2007) 2.38

Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host. Blood (2007) 2.35

Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group. J Proteome Res (2009) 2.33

Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice. Arthritis Rheum (2011) 2.33

Practical implementation issues and challenges for biobanks in the return of individual research results. Genet Med (2012) 2.32

Operative drainage following pancreatic resection: analysis of 1122 patients resected over 5 years at a single institution. Ann Surg (2013) 2.29

Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70. Cancer Res (2007) 2.27

Endoscopic ultrasound-guided fine-needle aspiration. A cytopathologist's perspective. Am J Clin Pathol (2003) 2.25

PAMPs and DAMPs: signal 0s that spur autophagy and immunity. Immunol Rev (2012) 2.24

Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis. Arch Intern Med (2009) 2.23

The management of antithrombotic agents for patients undergoing GI endoscopy. Gastrointest Endosc (2015) 2.23

Analytical validation of serum proteomic profiling for diagnosis of prostate cancer: sources of sample bias. Clin Chem (2007) 2.23

Pancreatic adenocarcinoma: the actual 5-year survivors. J Gastrointest Surg (2007) 2.22

High-mobility group box 1, oxidative stress, and disease. Antioxid Redox Signal (2011) 2.19

Multitasking: association between poorer performance and a history of recurrent falls. J Am Geriatr Soc (2007) 2.17

Tumor exosomes inhibit differentiation of bone marrow dendritic cells. J Immunol (2007) 2.16

Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b. Clin Cancer Res (2007) 2.15

Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways. Gastroenterology (2010) 2.13

Defining morbidity after pancreaticoduodenectomy: use of a prospective complication grading system. J Am Coll Surg (2007) 2.12

Laparoscopic versus open subtotal gastrectomy for adenocarcinoma: a case-control study. Ann Surg Oncol (2009) 2.10

Endoscopic transmural drainage of peripancreatic fluid collections: outcomes and predictors of treatment success in 211 consecutive patients. J Gastrointest Surg (2011) 2.09

Endoscopic ultrasound-guided fine needle aspiration biopsy of patients with suspected pancreatic cancer: diagnostic accuracy and acute and 30-day complications. Am J Gastroenterol (2003) 2.07

Impact of steatosis on perioperative outcome following hepatic resection. J Gastrointest Surg (2003) 2.05

Evaluation and management of autoimmune pancreatitis: experience at a large US center. Am J Gastroenterol (2009) 2.04

Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer. Clin Cancer Res (2004) 2.02

Promoter hypermethylation profile of kidney cancer. Clin Cancer Res (2004) 2.02

CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. Lab Invest (2004) 2.01

Total pancreatectomy and islet autotransplantation for chronic pancreatitis. J Am Coll Surg (2012) 2.00

Solitary rectal ulcer syndrome: endoscopic spectrum and review of the literature. Gastrointest Endosc (2005) 1.99

Survival after hepatic resection for metastatic colorectal cancer: trends in outcomes for 1,600 patients during two decades at a single institution. J Am Coll Surg (2010) 1.98

Endoscopic ultrasound-guided fine needle aspiration is superior to lymph node echofeatures: a prospective evaluation of mediastinal and peri-intestinal lymphadenopathy. Am J Gastroenterol (2004) 1.95

EUS-guided FNA of peritoneal carcinomatosis in patients with unknown primary malignancy. Gastrointest Endosc (2009) 1.94

Intraductal papillary neoplasm of the bile duct: a biliary equivalent to intraductal papillary mucinous neoplasm of the pancreas? Hepatology (2012) 1.94

The yield and the predictors of esophageal pathology when upper endoscopy is used for the initial evaluation of dysphagia. Gastrointest Endosc (2005) 1.93

Quality of life improves for pediatric patients after total pancreatectomy and islet autotransplant for chronic pancreatitis. Clin Gastroenterol Hepatol (2011) 1.93

Histopathologic correlates of noncalcific chronic pancreatitis by EUS: a prospective tissue characterization study. Gastrointest Endosc (2007) 1.93

Endoscopic ultrasound-guided fine-needle aspiration biopsy: a powerful tool to obtain samples from small lesions. Cancer (2004) 1.92

High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab (2011) 1.89

Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents. Clin Cancer Res (2002) 1.89

Antibody responses of variable lymphocyte receptors in the lamprey. Nat Immunol (2008) 1.87

Endoscopic ultrasound-guided fine needle aspiration biopsy of suspected cholangiocarcinoma. Clin Gastroenterol Hepatol (2004) 1.86

Prognostic significance of pathologic nodal status in patients with resected pancreatic cancer. J Gastrointest Surg (2007) 1.86

A functional anatomic defect of the cystic fibrosis airway. Am J Respir Crit Care Med (2014) 1.85

A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer. Sci Transl Med (2012) 1.84

Exosomes and cancer: a newly described pathway of immune suppression. Clin Cancer Res (2011) 1.83

Progress in structure based drug design for G protein-coupled receptors. J Med Chem (2011) 1.82

Robotic-assisted major pancreatic resection and reconstruction. Arch Surg (2010) 1.82

Autophagy inhibition in combination cancer treatment. Curr Opin Investig Drugs (2009) 1.79

HMGB1 in cancer: good, bad, or both? Clin Cancer Res (2013) 1.79

The role of pancreatic cyst fluid molecular analysis in predicting cyst pathology. Clin Gastroenterol Hepatol (2005) 1.78

Increased pulmonary vascular endothelin B receptor expression and responsiveness to endothelin-1 in cirrhotic and portal hypertensive rats: a potential mechanism in experimental hepatopulmonary syndrome. J Hepatol (2003) 1.78

Postsurgical disparity in survival between African Americans and Caucasians with colonic adenocarcinoma. Cancer (2004) 1.78

Endoscopic ultrasound-guided drainage of pelvic abscess without fluoroscopy guidance. J Gastroenterol Hepatol (2010) 1.77

Survival after resection of pancreatic adenocarcinoma: results from a single institution over three decades. Ann Surg Oncol (2011) 1.75

Awareness of guidelines and trends in the management of suspected pancreatic cystic neoplasms: survey results among general gastroenterologists and EUS specialists. Gastrointest Endosc (2008) 1.74