Published in Biomaterials on February 20, 2011
Poly(2-oxazoline)s as polymer therapeutics. Macromol Rapid Commun (2012) 1.07
Statin therapy lowers muscle sympathetic nerve activity and oxidative stress in patients with heart failure. Am J Physiol Heart Circ Physiol (2012) 1.01
Conjugates of superoxide dismutase 1 with amphiphilic poly(2-oxazoline) block copolymers for enhanced brain delivery: synthesis, characterization and evaluation in vitro and in vivo. Mol Pharm (2012) 0.87
Novel treatment of neuroinflammation against low back pain by soluble fullerol nanoparticles. Spine (Phila Pa 1976) (2013) 0.83
Drug-induced morphology switch in drug delivery systems based on poly(2-oxazoline)s. ACS Nano (2014) 0.83
A Low Protein Binding Cationic Poly(2-oxazoline) as Non-Viral Vector. Macromol Biosci (2015) 0.81
Agile delivery of protein therapeutics to CNS. J Control Release (2014) 0.79
Distribution and biomarkers of carbon-14-labeled fullerene C60 ([(14) C(U)]C60 ) in female rats and mice for up to 30 days after intravenous exposure. J Appl Toxicol (2015) 0.79
On the Reaction Mechanism of the Rhodium-Catalyzed Arylation of Fullerene (C60) with Organoboron Compounds in the Presence of Water. ChemistryOpen (2015) 0.76
Polymer Coatings of Cochlear Implant Electrode Surface - An Option for Improving Electrode-Nerve-Interface by Blocking Fibroblast Overgrowth. PLoS One (2016) 0.75
Toxic potential of materials at the nanolevel. Science (2006) 19.24
Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med (2000) 6.25
ROS stress in cancer cells and therapeutic implications. Drug Resist Updat (2004) 5.20
Reactive oxygen species and the central nervous system. J Neurochem (1992) 4.27
Role of oxidative stress in cardiovascular diseases. J Hypertens (2000) 3.73
Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension. Circulation (1997) 3.28
Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro. Toxicol Lett (2005) 2.76
Fullerene derivatives: an attractive tool for biological applications. Eur J Med Chem (2003) 2.18
Cellular localisation of a water-soluble fullerene derivative. Biochem Biophys Res Commun (2002) 2.08
Carboxyfullerenes as neuroprotective agents. Proc Natl Acad Sci U S A (1997) 2.05
Functionalized fullerenes in water. The first 10 years of their chemistry, biology, and nanoscience. Acc Chem Res (2003) 1.96
Poly(2-oxazoline)s: a polymer class with numerous potential applications. Angew Chem Int Ed Engl (2009) 1.75
Hypoxia, oxidative stress and rheumatoid arthritis. Br Med Bull (1995) 1.65
Superoxide mediates angiotensin II-induced influx of extracellular calcium in neural cells. Hypertension (2005) 1.50
Redox signaling in central neural regulation of cardiovascular function. Prog Biophys Mol Biol (2004) 1.46
Biomedical potential of the reactive oxygen species generation and quenching by fullerenes (C60). Biomaterials (2008) 1.25
A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties. Free Radic Biol Med (2004) 1.24
The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. Biomaterials (2008) 1.19
Synthesis, biodistribution and excretion of radiolabeled poly(2-alkyl-2-oxazoline)s. J Control Release (2007) 1.17
Doubly amphiphilic poly(2-oxazoline)s as high-capacity delivery systems for hydrophobic drugs. Biomaterials (2010) 1.16
Mitochondria-produced superoxide mediates angiotensin II-induced inhibition of neuronal potassium current. Am J Physiol Cell Physiol (2010) 1.14
C(60) and water-soluble fullerene derivatives as antioxidants against radical-initiated lipid peroxidation. J Med Chem (1999) 1.14
Preclinical studies on safety of fullerene upon acute oral administration and evaluation for no mutagenesis. Toxicology (2006) 1.09
The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase. Biomaterials (2010) 1.04
Angiotensin II-dependent superoxide: effects on hypertension and vascular dysfunction. Hypertension (2008) 1.01
Antioxidant effects of water-soluble fullerene derivatives against ultraviolet ray or peroxylipid through their action of scavenging the reactive oxygen species in human skin keratinocytes. Biomed Pharmacother (2005) 0.95
Protein modification with amphiphilic block copoly(2-oxazoline)s as a new platform for enhanced cellular delivery. Mol Pharm (2010) 0.93
SOD activity of carboxyfullerenes predicts their neuroprotective efficacy: a structure-activity study. Nanomedicine (2008) 0.93
In vitro and in vivo genotoxicity tests on fullerene C60 nanoparticles. Toxicol Lett (2009) 0.90
Carboxyfullerenes localize within mitochondria and prevent the UVB-induced intrinsic apoptotic pathway. Exp Dermatol (2007) 0.89
The water-soluble fullerene derivative "Radical Sponge" exerts cytoprotective action against UVA irradiation but not visible-light-catalyzed cytotoxicity in human skin keratinocytes. Bioorg Med Chem Lett (2006) 0.89
Defensive effects of fullerene-C60/liposome complex against UVA-induced intracellular reactive oxygen species generation and cell death in human skin keratinocytes HaCaT, associated with intracellular uptake and extracellular excretion of fullerene-C60. J Photochem Photobiol B (2009) 0.88
Synthetic polymeric substrates as potent pro-oxidant versus anti-oxidant regulators of cytoskeletal remodeling and cell apoptosis. J Cell Physiol (2009) 0.86
The protection of cells from nitric oxide-mediated apoptotic death by mechanochemically synthesized fullerene (C(60)) nanoparticles. Biomaterials (2009) 0.86
Use of fullerenes in cosmetics. Recent Pat Biotechnol (2009) 0.85
The effect of squalane-dissolved fullerene-C60 on adipogenesis-accompanied oxidative stress and macrophage activation in a preadipocyte-monocyte co-culture system. Biomaterials (2010) 0.84
A water-soluble fullerene vesicle alleviates angiotensin II-induced oxidative stress in human umbilical venous endothelial cells. Hypertens Res (2008) 0.83
Highly stable C(60)/poly(vinylpyrrolidone) charge-transfer complexes afford new predictions for biological applications of underivatized fullerenes. J Med Chem (2000) 0.79
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell (2008) 6.16
Endocytosis of nanomedicines. J Control Release (2010) 3.23
Does acupuncture have additional value to standard poststroke motor rehabilitation? Stroke (2002) 2.71
Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers. J Control Release (2008) 2.63
Nanosized cationic hydrogels for drug delivery: preparation, properties and interactions with cells. Adv Drug Deliv Rev (2002) 2.19
Nanogels for oligonucleotide delivery to the brain. Bioconjug Chem (2004) 1.94
Role of CuZn superoxide dismutase on carotid body function in heart failure rabbits. Cardiovasc Res (2008) 1.75
Prognostic significance of VEGF expression in osteosarcoma: a meta-analysis. Tumour Biol (2013) 1.65
Optimal structure requirements for pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells. J Pharmacol Exp Ther (2003) 1.61
Elevated mitochondrial superoxide contributes to enhanced chemoreflex in heart failure rabbits. Am J Physiol Regul Integr Comp Physiol (2009) 1.58
Polyplex Nanogel formulations for drug delivery of cytotoxic nucleoside analogs. J Control Release (2005) 1.52
The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans. J Cell Biol (2007) 1.49
Role of gamma-glutamyl transpeptidase in redox regulation of K+ channel remodeling in postmyocardial infarction rat hearts. Am J Physiol Cell Physiol (2009) 1.45
Polymer micelle with cross-linked ionic core. J Am Chem Soc (2005) 1.40
A macrophage-nanozyme delivery system for Parkinson's disease. Bioconjug Chem (2007) 1.38
Domain registration in raft-mimicking lipid mixtures studied using polymer-tethered lipid bilayers. Biophys J (2006) 1.36
Cell-mediated drug delivery. Expert Opin Drug Deliv (2011) 1.33
Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport. Bioconjug Chem (2008) 1.33
Amphiphilic block copolymers enhance cellular uptake and nuclear entry of polyplex-delivered DNA. Bioconjug Chem (2008) 1.31
A dysfunctional tricarboxylic acid cycle enhances fitness of Staphylococcus epidermidis during β-lactam stress. MBio (2013) 1.28
Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages. J Control Release (2010) 1.28
Polymer micelles with cross-linked ionic cores for delivery of anticancer drugs. J Control Release (2006) 1.28
Polypeptide point modifications with fatty acid and amphiphilic block copolymers for enhanced brain delivery. Bioconjug Chem (2005) 1.26
Design and formulation of polyplexes based on pluronic-polyethyleneimine conjugates for gene transfer. Bioconjug Chem (2002) 1.25
Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast. Free Radic Biol Med (2013) 1.23
Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections. Nanomedicine (2013) 1.21
Folate-decorated nanogels for targeted therapy of ovarian cancer. Biomaterials (2011) 1.21
The effect of the nonionic block copolymer pluronic P85 on gene expression in mouse muscle and antigen-presenting cells. Biomaterials (2008) 1.19
The exploitation of differential endocytic pathways in normal and tumor cells in the selective targeting of nanoparticulate chemotherapeutic agents. Biomaterials (2009) 1.17
Synthesis, biodistribution and excretion of radiolabeled poly(2-alkyl-2-oxazoline)s. J Control Release (2007) 1.17
Sensitization of cells overexpressing multidrug-resistant proteins by pluronic P85. Pharm Res (2003) 1.17
Doubly amphiphilic poly(2-oxazoline)s as high-capacity delivery systems for hydrophobic drugs. Biomaterials (2010) 1.16
Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells. J Control Release (2005) 1.16
Mitochondria-produced superoxide mediates angiotensin II-induced inhibition of neuronal potassium current. Am J Physiol Cell Physiol (2010) 1.14
Macrophage delivery of therapeutic nanozymes in a murine model of Parkinson's disease. Nanomedicine (Lond) (2010) 1.12
Polymer micelles with cross-linked polyanion core for delivery of a cationic drug doxorubicin. J Control Release (2009) 1.11
Synthesis and evaluation of a star amphiphilic block copolymer from poly(epsilon-caprolactone) and poly(ethylene glycol) as a potential drug delivery carrier. Bioconjug Chem (2005) 1.11
Nanocarriers for delivery of platinum anticancer drugs. Adv Drug Deliv Rev (2013) 1.11
Comparative manufacture and cell-based delivery of antiretroviral nanoformulations. Int J Nanomedicine (2011) 1.11
Differential metabolic responses to pluronic in MDR and non-MDR cells: a novel pathway for chemosensitization of drug resistant cancers. J Control Release (2009) 1.11
Distribution kinetics of a micelle-forming block copolymer Pluronic P85. J Control Release (2004) 1.09
Polymeric micelles with ionic cores containing biodegradable cross-links for delivery of chemotherapeutic agents. Biomacromolecules (2010) 1.09
Redox regulation of Ito remodeling in diabetic rat heart. Am J Physiol Heart Circ Physiol (2004) 1.08
Poly(2-oxazoline)s as polymer therapeutics. Macromol Rapid Commun (2012) 1.07
Effect of pluronic P85 on ATPase activity of drug efflux transporters. Pharm Res (2004) 1.07
Novel nanomaterials for clinical neuroscience. J Neuroimmune Pharmacol (2008) 1.07
Exercise training prevents the exaggerated exercise pressor reflex in rats with chronic heart failure. J Appl Physiol (1985) (2010) 1.07
Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism. Am J Physiol Cell Physiol (2010) 1.05
Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: pluronic P85. Mol Pharm (2006) 1.05
Real-time imaging of NADPH oxidase activity in living cells using a novel fluorescent protein reporter. PLoS One (2013) 1.04
The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase. Biomaterials (2010) 1.04
Synergistic combinations of multiple chemotherapeutic agents in high capacity poly(2-oxazoline) micelles. Mol Pharm (2012) 1.03
Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers. J Control Release (2010) 1.03
Structure-property relationship in cytotoxicity and cell uptake of poly(2-oxazoline) amphiphiles. J Control Release (2011) 1.03
Mixed polymer micelles of amphiphilic and cationic copolymers for delivery of antisense oligonucleotides. J Drug Target (2004) 1.02
Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain. Free Radic Biol Med (2010) 1.02
Proline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell death. Free Radic Biol Med (2012) 1.02
Transport across the blood-brain barrier of pluronic leptin. J Pharmacol Exp Ther (2010) 1.01
Pluronic-modified superoxide dismutase 1 attenuates angiotensin II-induced increase in intracellular superoxide in neurons. Free Radic Biol Med (2010) 1.01
Block ionomer complexes as prospective nanocontainers for drug delivery. J Control Release (2006) 1.01
Statin therapy lowers muscle sympathetic nerve activity and oxidative stress in patients with heart failure. Am J Physiol Heart Circ Physiol (2012) 1.01
Mitochondrial-localized NADPH oxidase 4 is a source of superoxide in angiotensin II-stimulated neurons. Am J Physiol Heart Circ Physiol (2013) 1.00
Antioxidant-based therapies for angiotensin II-associated cardiovascular diseases. Am J Physiol Regul Integr Comp Physiol (2013) 1.00
Alu-directed transcriptional regulation of some novel miRNAs. BMC Genomics (2009) 1.00
Polyelectrolyte complex optimization for macrophage delivery of redox enzyme nanoparticles. Nanomedicine (Lond) (2011) 0.99
Protein conjugation with amphiphilic block copolymers for enhanced cellular delivery. Bioconjug Chem (2008) 0.99
Core cross-linked block ionomer micelles as pH-responsive carriers for cis-diamminedichloroplatinum(II). J Control Release (2011) 0.98
Specific transfection of inflamed brain by macrophages: a new therapeutic strategy for neurodegenerative diseases. PLoS One (2013) 0.97
Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis. J Cereb Blood Flow Metab (2006) 0.97
Mitochondrial dysfunction and mitochondrial-produced reactive oxygen species: new targets for neurogenic hypertension? Hypertension (2008) 0.96
Cross-linked antioxidant nanozymes for improved delivery to CNS. Nanomedicine (2011) 0.96
Supported membranes with well-defined polymer tethers--incorporation of cell receptors. Chemphyschem (2004) 0.95
Stabilization of virus-like particles with poly(2-oxazoline)s. Angew Chem Int Ed Engl (2011) 0.95
Synthesis and characterization of star poly(epsilon-caprolactone)-b-poly(ethylene glycol) and poly(L-lactide)-b-poly(ethylene glycol) copolymers: evaluation as drug delivery carriers. Bioconjug Chem (2008) 0.94
Newborn lamb coronary artery reactivity is programmed by early gestation dexamethasone before the onset of systemic hypertension. Am J Physiol Regul Integr Comp Physiol (2005) 0.94
Micellar formulations for drug delivery based on mixtures of hydrophobic and hydrophilic Pluronic block copolymers. J Control Release (2004) 0.94
Cell-mediated transfer of catalase nanoparticles from macrophages to brain endothelial, glial and neuronal cells. Nanomedicine (Lond) (2011) 0.94
First aldehyde-functionalized poly(2-oxazoline)s for chemoselective ligation. Macromol Biosci (2005) 0.94
Template-assisted synthesis of nanogels from Pluronic-modified poly(acrylic acid). J Drug Target (2006) 0.93
Protein modification with amphiphilic block copoly(2-oxazoline)s as a new platform for enhanced cellular delivery. Mol Pharm (2010) 0.93
Regulation of Kv4 channel expression in failing rat heart by the thioredoxin system. Am J Physiol Heart Circ Physiol (2008) 0.93
Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant. J Control Release (2008) 0.92