PubRank

Thomas N Williams

Author PubWeight™ 159.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015 7.99
2 Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet 2015 6.13
3 Sickle-cell disease. Lancet 2010 5.64
4 Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates. Lancet 2012 4.62
5 Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet 2009 4.30
6 A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat Genet 2007 4.23
7 Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study. Lancet 2011 3.78
8 Stable and unstable malaria hotspots in longitudinal cohort studies in Kenya. PLoS Med 2010 3.78
9 Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria. Vaccine 2004 3.51
10 Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway. Cell 2013 3.49
11 Sickle cell disease in Africa: a neglected cause of early childhood mortality. Am J Prev Med 2011 3.35
12 CISH and susceptibility to infectious diseases. N Engl J Med 2010 3.31
13 HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria. Clin Infect Dis 2009 2.80
14 Profile: The Kilifi Health and Demographic Surveillance System (KHDSS). Int J Epidemiol 2012 2.64
15 Heritability of malaria in Africa. PLoS Med 2005 2.49
16 Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis. Nat Commun 2010 2.46
17 Global burden of sickle cell anaemia in children under five, 2010-2050: modelling based on demographics, excess mortality, and interventions. PLoS Med 2013 2.36
18 Iron deficiency and malaria among children living on the coast of Kenya. J Infect Dis 2004 2.34
19 Relationship between exposure, clinical malaria, and age in an area of changing transmission intensity. Am J Trop Med Hyg 2008 2.29
20 The global distribution of the Duffy blood group. Nat Commun 2011 2.06
21 Malaria and nutritional status in children living on the coast of Kenya. Am J Clin Nutr 2004 1.90
22 High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya. Vaccine 2005 1.89
23 Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo. Blood 2006 1.83
24 Malaria as a cause of morbidity and mortality in children with homozygous sickle cell disease on the coast of Kenya. Clin Infect Dis 2009 1.74
25 The effect of alpha+-thalassaemia on the incidence of malaria and other diseases in children living on the coast of Kenya. PLoS Med 2006 1.73
26 Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria. Hum Mol Genet 2007 1.72
27 Mortality in sickle cell anemia in Africa: a prospective cohort study in Tanzania. PLoS One 2011 1.71
28 Validating physician-certified verbal autopsy and probabilistic modeling (InterVA) approaches to verbal autopsy interpretation using hospital causes of adult deaths. Popul Health Metr 2011 1.63
29 Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome. PLoS One 2011 1.62
30 Global migration and the changing distribution of sickle haemoglobin: a quantitative study of temporal trends between 1960 and 2000. Lancet Glob Health 2014 1.58
31 Experiences with community engagement and informed consent in a genetic cohort study of severe childhood diseases in Kenya. BMC Med Ethics 2010 1.54
32 Acquisition of growth-inhibitory antibodies against blood-stage Plasmodium falciparum. PLoS One 2008 1.53
33 Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes. Hum Mol Genet 2009 1.50
34 Sensitivity of hospital-based surveillance for severe disease: a geographic information system analysis of access to care in Kilifi district, Kenya. Bull World Health Organ 2010 1.49
35 B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area. J Infect Dis 2005 1.47
36 Geographic access to care is not a determinant of child mortality in a rural Kenyan setting with high health facility density. BMC Public Health 2010 1.46
37 High mortality from Plasmodium falciparum malaria in children living with sickle cell anemia on the coast of Kenya. Blood 2010 1.44
38 A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus. Proc Natl Acad Sci U S A 2010 1.41
39 Copy number, linkage disequilibrium and disease association in the FCGR locus. Hum Mol Genet 2010 1.41
40 Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization. Blood 2009 1.40
41 Spatial distribution of G6PD deficiency variants across malaria-endemic regions. Malar J 2013 1.37
42 Excess child mortality after discharge from hospital in Kilifi, Kenya: a retrospective cohort analysis. Bull World Health Organ 2011 1.34
43 Incidence and clinical characteristics of group A rotavirus infections among children admitted to hospital in Kilifi, Kenya. PLoS Med 2008 1.31
44 Defining clinical malaria: the specificity and incidence of endpoints from active and passive surveillance of children in rural Kenya. PLoS One 2010 1.30
45 The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria. Infect Immun 2006 1.28
46 Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria. PLoS One 2007 1.28
47 Social autopsy: INDEPTH Network experiences of utility, process, practices, and challenges in investigating causes and contributors to mortality. Popul Health Metr 2011 1.27
48 Imputation-based meta-analysis of severe malaria in three African populations. PLoS Genet 2013 1.25
49 Determinants of anemia among preschool children in rural, western Kenya. Am J Trop Med Hyg 2013 1.22
50 Antibodies among men and children to placental-binding Plasmodium falciparum-infected erythrocytes that express var2csa. Am J Trop Med Hyg 2007 1.21
51 Survival and haematological recovery of children with severe malaria transfused in accordance to WHO guidelines in Kilifi, Kenya. Malar J 2008 1.19
52 Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations. J Infect Dis 2009 1.17
53 Co-inheritance of alpha+-thalassaemia and sickle trait results in specific effects on haematological parameters. Br J Haematol 2006 1.11
54 Transmission-dependent tolerance to multiclonal Plasmodium falciparum infection. J Infect Dis 2009 1.10
55 An observational study of children with sickle cell disease in Kilifi, Kenya. Br J Haematol 2009 1.09
56 The burden and consequences of inherited blood disorders among young children in western Kenya. Matern Child Nutr 2012 1.08
57 Iron deficiency and acute seizures: results from children living in rural Kenya and a meta-analysis. PLoS One 2010 1.08
58 Consulting communities on feedback of genetic findings in international health research: sharing sickle cell disease and carrier information in coastal Kenya. BMC Med Ethics 2013 1.06
59 Blood groups and malaria: fresh insights into pathogenesis and identification of targets for intervention. Curr Opin Hematol 2009 1.06
60 Management of severe malaria in children: proposed guidelines for the United Kingdom. BMJ 2005 1.03
61 Verbal autopsy as a tool for identifying children dying of sickle cell disease: a validation study conducted in Kilifi district, Kenya. BMC Med 2014 1.03
62 The use of cryopreserved mature trophozoites in assessing antibody recognition of variant surface antigens of Plasmodium falciparum-infected erythrocytes. J Immunol Methods 2004 1.02
63 Characterization of a Plasmodium falciparum macrophage-migration inhibitory factor homologue. J Infect Dis 2007 1.01
64 Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1. Malar J 2008 0.99
65 Haemoglobinopathies and resistance to malaria. Redox Rep 2003 0.99
66 Risk factors for high cerebral blood flow velocity and death in Kenyan children with Sickle Cell Anaemia: role of haemoglobin oxygen saturation and febrile illness. Br J Haematol 2009 0.99
67 The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya. Clin Infect Dis 2007 0.98
68 Epidemiological studies of the 'non-specific effects' of vaccines: I--data collection in observational studies. Trop Med Int Health 2009 0.96
69 The Jamaican historical experience of the impact of educational interventions on sickle cell disease child mortality. Am J Prev Med 2012 0.95
70 The distribution of haemoglobin C and its prevalence in newborns in Africa. Sci Rep 2013 0.95
71 Burden of disease in adults admitted to hospital in a rural region of coastal Kenya: an analysis of data from linked clinical and demographic surveillance systems. Lancet Glob Health 2014 0.95
72 Homozygosity and risk of childhood death due to invasive bacterial disease. BMC Med Genet 2009 0.95
73 Investigating the potential for ethnic group harm in collaborative genomics research in Africa: is ethnic stigmatisation likely? Soc Sci Med 2012 0.91
74 Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya. BMC Med Genet 2014 0.91
75 Falciparum malaria: current therapeutic challenges. Curr Opin Infect Dis 2004 0.91
76 Rotavirus genetic diversity, disease association, and temporal change in hospitalized rural Kenyan children. J Infect Dis 2010 0.91
77 A polymorphism of intercellular adhesion molecule-1 is associated with a reduced incidence of nonmalarial febrile illness in Kenyan children. Clin Infect Dis 2005 0.90
78 Manifestations of paediatric Leishmania infantum infections in Malta. Travel Med Infect Dis 2011 0.90
79 Phase II trial of standard versus increased transfusion volume in Ugandan children with acute severe anemia. BMC Med 2014 0.89
80 Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania. Haematologica 2011 0.89
81 Transfer of 4-hydroxynonenal from parasitized to non-parasitized erythrocytes in rosettes. Proposed role in severe malaria anemia. Br J Haematol 2012 0.88
82 Routine paediatric sickle cell disease (SCD) outpatient care in a rural Kenyan hospital: utilization and costs. PLoS One 2013 0.88
83 Association of the GNAS locus with severe malaria. Hum Genet 2008 0.87
84 Nutritional status of young children with inherited blood disorders in western Kenya. Am J Trop Med Hyg 2014 0.86
85 Nutritional iron status in children with alpha+ thalassemia and the sickle cell trait in a malaria endemic area on the coast of Kenya. Haematologica 2005 0.86
86 Common NFKBIL2 polymorphisms and susceptibility to pneumococcal disease: a genetic association study. Crit Care 2010 0.86
87 Parvovirus B19 infection and severe anaemia in Kenyan children: a retrospective case control study. BMC Infect Dis 2010 0.85
88 The genetic risk of acute seizures in African children with falciparum malaria. Epilepsia 2013 0.84
89 Epistasis between the haptoglobin common variant and α+thalassemia influences risk of severe malaria in Kenyan children. Blood 2014 0.82
90 How do hemoglobins S and C result in malaria protection? J Infect Dis 2011 0.80
91 Frequencies of peripheral blood myeloid cells in healthy Kenyan children with alpha+ thalassemia and the sickle cell trait. Am J Trop Med Hyg 2006 0.80
92 Online biomedical resources for malaria-related red cell disorders. Hum Mutat 2013 0.80
93 Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations. PLoS One 2009 0.80
94 Invasive Group A Streptococcus Infection among Children, Rural Kenya. Emerg Infect Dis 2016 0.79
95 Haptoglobin HP2-2 genotype, alpha-thalassaemia and acute seizures in children living in a malaria-endemic area. Epilepsy Res 2008 0.78
96 Knowing who to trust: exploring the role of 'ethical metadata' in mediating risk of harm in collaborative genomics research in Africa. BMC Med Ethics 2014 0.78
97 The "difficult patient" conundrum in sickle cell disease in Kenya: complex sociopolitical problems need wide multidimensional solutions. Am J Bioeth 2013 0.75
98 An assessment of the impact of host polymorphisms on Plasmodium falciparum var gene expression patterns among Kenyan children. BMC Infect Dis 2014 0.75
99 Lactate levels in severe malarial anaemia are associated with haemozoin-containing neutrophils and low levels of IL-12. Malar J 2006 0.75
100 Ciguatera poisoning in Vanuatu. Am J Trop Med Hyg 2003 0.75