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1
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Leptin is induced in the ischemic cerebral cortex and exerts neuroprotection through NF-kappaB/c-Rel-dependent transcription.
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2008
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1.72
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Mol Pharmacol
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The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension.
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2005
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J Biol Chem
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2005
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J Biol Chem
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6
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Histone deacetylase (HDAC) inhibitors reduce the glial inflammatory response in vitro and in vivo.
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2009
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1.16
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J Cereb Blood Flow Metab
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Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia.
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J Cereb Blood Flow Metab
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2012
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Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis.
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Mol Pharmacol
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2011
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1.07
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10
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Studies on the neuroprotective action of kynurenine mono-oxygenase inhibitors in post-ischemic brain damage.
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2003
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11
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12
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J Biol Chem
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2009
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1.03
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13
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Functional study in a yeast model of a novel succinate dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor.
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Hum Mol Genet
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2009
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J Cereb Blood Flow Metab
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1.01
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15
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Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription.
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Mol Pharmacol
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2011
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1.00
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16
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Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines.
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Eur J Immunol
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2006
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0.95
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17
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Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.
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Biochem Pharmacol
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2009
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0.95
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18
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Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria.
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PLoS One
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Post-ischemic brain damage: targeting PARP-1 within the ischemic neurovascular units as a realistic avenue to stroke treatment.
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A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation.
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J Immunol
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21
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Neuroprotective effects of propofol in models of cerebral ischemia: inhibition of mitochondrial swelling as a possible mechanism.
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2006
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0.92
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Neurochem Int
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The therapeutic potential of HDAC inhibitors in the treatment of multiple sclerosis.
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Inhibition of poly(ADP-ribose) glycohydrolase by gallotannin selectively up-regulates expression of proinflammatory genes.
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Mol Pharmacol
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2004
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0.89
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25
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Induction of CD83+CD14+ nondendritic antigen-presenting cells by exposure of monocytes to IFN-alpha.
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J Immunol
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Nuclear factor-kappaB as a molecular target for migraine therapy.
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Ann Neurol
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PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity.
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Mult Scler
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0.88
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High expression of indoleamine 2,3-dioxygenase gene in prostate cancer.
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2008
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AMP-dependent hypothermia affords protection from ischemic brain injury.
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18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis.
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Ocul Immunol Inflamm
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2011
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Antidromic vasodilatation and the migraine mechanism.
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On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives.
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Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts.
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Biochem Cell Biol
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0.84
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Poly(ADP-ribose) polymerase as a key player in excitotoxicity and post-ischemic brain damage.
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Toxicol Lett
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Targeting poly(ADP-ribose) polymerase-1 as a promising approach for immunomodulation in multiple sclerosis?
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Trends Mol Med
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1B/(-)IRE DMT1 expression during brain ischemia contributes to cell death mediated by NF-κB/RelA acetylation at Lys310.
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PLoS One
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Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3 beta pathway in cultured cortical neurons and protects against neurotoxic insults.
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J Neurochem
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Indoleamine 2,3-dioxygenase+ cells correspond to the BDCA2+ plasmacytoid dendritic cells in human melanoma sentinel nodes.
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Brain ischemic preconditioning does not require PARP-1.
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Relevance of high-mobility group protein box 1 to neurodegeneration.
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Int Rev Neurobiol
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Human Langerhans cells are immature in melanoma sentinel lymph nodes.
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Exp Neurol
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Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation.
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Horm Cancer
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Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance.
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Eur J Neurosci
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2012
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Glucose deprivation converts poly(ADP-ribose) polymerase-1 hyperactivation into a transient energy-producing process.
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J Biol Chem
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2013
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0.77
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46
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PARP inhibition delays progression of mitochondrial encephalopathy in mice.
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0.76
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Carboxymethyl beta-glucan binds to corneal epithelial cells and increases cell adhesion to laminin and resistance to oxidative stress.
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2007
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