Ezio Bonifacio

Author PubWeight™ 103.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Risk of pediatric celiac disease according to HLA haplotype and country. N Engl J Med 2014 5.44
2 Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 2013 3.65
3 Early infant feeding and risk of developing type 1 diabetes-associated autoantibodies. JAMA 2003 3.39
4 Diabetes Antibody Standardization Program: first assay proficiency evaluation. Diabetes 2003 3.09
5 Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics. Diabetes 2004 2.74
6 The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results. Pediatr Diabetes 2008 2.60
7 Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 2005 2.39
8 Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes. J Clin Invest 2004 2.34
9 Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents. Ann Intern Med 2004 2.31
10 A report on the International Transglutaminase Autoantibody Workshop for Celiac Disease. Am J Gastroenterol 2009 1.94
11 Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells. J Clin Invest 2008 1.73
12 Natural history of type 1 diabetes. Diabetes 2005 1.68
13 Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance. Diabetes 2006 1.65
14 Bone marrow as an alternative site for islet transplantation. Blood 2009 1.61
15 Elimination of dietary gluten does not reduce titers of type 1 diabetes-associated autoantibodies in high-risk subjects. Diabetes Care 2002 1.59
16 Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes. J Immunol 2007 1.49
17 Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells. Diabetes 2008 1.49
18 Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells. Diabetes 2006 1.48
19 Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4. Diabetes Care 2009 1.42
20 Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes. Diabetes 2011 1.39
21 Primary dietary intervention study to reduce the risk of islet autoimmunity in children at increased risk for type 1 diabetes: the BABYDIET study. Diabetes Care 2011 1.38
22 Predictors of postpartum diabetes in women with gestational diabetes mellitus. Diabetes 2006 1.35
23 No effect of the 1alpha,25-dihydroxyvitamin D3 on beta-cell residual function and insulin requirement in adults with new-onset type 1 diabetes. Diabetes Care 2010 1.26
24 High-resolution SNP scan of chromosome 6p21 in pooled samples from patients with complex diseases. Genomics 2003 1.22
25 Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes. Diabetes Care 2004 1.21
26 The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study. Diabetologia 2015 1.20
27 Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes. Diabetes 2004 1.18
28 Modulating the natural history of type 1 diabetes in children at high genetic risk by mucosal insulin immunization. Curr Diab Rep 2008 1.15
29 GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes. Diabetes 2007 1.15
30 Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes. Diabetes 2011 1.14
31 Combined testing of antibody titer and affinity improves insulin autoantibody measurement: Diabetes Antibody Standardization Program. Clin Immunol 2006 1.13
32 A genomic toolkit to investigate kinesin and myosin motor function in cells. Nat Cell Biol 2013 1.11
33 Transplantation of human islets without immunosuppression. Proc Natl Acad Sci U S A 2013 1.10
34 Delayed exposure to wheat and barley proteins reduces diabetes incidence in non-obese diabetic mice. Clin Immunol 2004 1.08
35 Up-regulation of CD1d expression restores the immunoregulatory function of NKT cells and prevents autoimmune diabetes in nonobese diabetic mice. J Immunol 2004 1.07
36 Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function. Stem Cells 2010 1.07
37 CXCR1/2 inhibition enhances pancreatic islet survival after transplantation. J Clin Invest 2012 1.05
38 Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children. J Autoimmun 2011 1.04
39 Six months of gluten-free diet do not influence autoantibody titers, but improve insulin secretion in subjects at high risk for type 1 diabetes. J Clin Endocrinol Metab 2003 1.03
40 SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset. Rev Diabet Stud 2008 1.02
41 An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes. Diabetes 2011 1.02
42 Role of CCL2/MCP-1 in islet transplantation. Cell Transplant 2010 1.01
43 Alloantibody and autoantibody monitoring predicts islet transplantation outcome in human type 1 diabetes. Diabetes 2012 0.99
44 The second murine autoantibody workshop: remarkable interlaboratory concordance for radiobinding assays to identify insulin autoantibodies in nonobese diabetic mice. Ann N Y Acad Sci 2003 0.98
45 Transplant estimated function: a simple index to evaluate beta-cell secretion after islet transplantation. Diabetes Care 2007 0.98
46 IL-7 abrogates suppressive activity of human CD4+CD25+FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells. J Immunol 2012 0.98
47 Characterization of antibody responses to endogenous and exogenous antigen in the nonobese diabetic mouse. Clin Immunol 2003 0.96
48 BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1. Diabetes 2010 0.95
49 Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens. J Immunol 2002 0.93
50 Azide and Tween-20 reduce binding to autoantibody epitopes of islet antigen-2; implications for assay performance and reproducibility. J Immunol Methods 2009 0.91
51 Tissue factor and CCL2/monocyte chemoattractant protein-1 released by human islets affect islet engraftment in type 1 diabetic recipients. J Clin Endocrinol Metab 2004 0.91
52 Predicting type 1 diabetes. Curr Diab Rep 2005 0.91
53 Impaired insulin turnover in islets from type 2 diabetic patients. Islets 2010 0.90
54 Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model. Diabetologia 2013 0.89
55 Neonatal Bacille Calmette-Guerin vaccination and type 1 diabetes. Diabetes Care 2005 0.89
56 Differentiation, expansion, and homeostasis of autoreactive T cells in type 1 diabetes mellitus. Curr Diab Rep 2009 0.89
57 The use of biomaterials in islet transplantation. Curr Diab Rep 2011 0.88
58 Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes. Diabetologia 2014 0.87
59 HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes. J Clin Endocrinol Metab 2009 0.87
60 Measuring T cell receptor and T cell gene expression diversity in antigen-responsive human CD4+ T cells. J Immunol Methods 2013 0.87
61 Predicting type 1 diabetes using autoantibodies: the latest results from the diabetes autoantibody standardization program. Diabetes Technol Ther 2002 0.86
62 German new onset diabetes in the young incident cohort study: DiMelli study design and first-year results. Rev Diabet Stud 2010 0.84
63 Rapamycin does not adversely affect intrahepatic islet engraftment in mice and improves early islet engraftment in humans. Islets 2010 0.84
64 Concentration and activity of the soluble form of the interleukin-7 receptor α in type 1 diabetes identifies an interplay between hyperglycemia and immune function. Diabetes 2013 0.83
65 Humoral autoimmune responses to glutamic acid decarboxylase have similar target epitopes and subclass that show titer-dependent disease association. Clin Immunol 2005 0.83
66 Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice. PLoS One 2010 0.83
67 Relevance of hyperglycemia on the timing of functional loss of allogeneic islet transplants: implication for mouse model. Transplantation 2007 0.83
68 Activation of islet autoreactive naïve T cells in infants is influenced by homeostatic mechanisms and antigen-presenting capacity. Diabetes 2013 0.83
69 Influence of early nutritional components on the development of murine autoimmune diabetes. Ann Nutr Metab 2009 0.82
70 Pretransplantation GAD-autoantibody status to guide prophylactic antibody induction therapy in simultaneous pancreas and kidney transplantation. Transplantation 2013 0.82
71 Identification of insulin autoantibodies of IgA isotype that preferentially target non-human insulin. Clin Immunol 2007 0.82
72 Prospective evaluation of risk factors for the development of islet autoimmunity and type 1 diabetes during puberty--TEENDIAB: study design. Pediatr Diabetes 2011 0.82
73 A simplified method to assess affinity of insulin autoantibodies. Clin Immunol 2010 0.81
74 Monoclonal antibody 76F distinguishes IA-2 from IA-2beta and overlaps an autoantibody epitope. J Autoimmun 2006 0.81
75 Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: implications for early screening. Diabetologia 2014 0.80
76 Beta-cell autoimmunity. Methods Mol Biol 2012 0.78
77 Radiobinding assay for detecting autoantibodies to single epitopes. J Immunol Methods 2008 0.78
78 Fine mapping of diabetes-associated IA-2 specific autoantibodies. J Autoimmun 2003 0.77
79 IA-2 autoantibody affinity in children at risk for type 1 diabetes. Clin Immunol 2012 0.77
80 Isolation of human monoclonal autoantibodies derived from pancreatic lymph node and peripheral blood B cells of islet autoantibody-positive patients. Diabetologia 2016 0.77
81 Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk. Pediatr Diabetes 2014 0.76
82 Interleukin-7 and type 1 diabetes. Curr Diab Rep 2014 0.76
83 Gluten-free diet in subjects at risk for type 1 diabetes: a tool for delaying progression to clinical disease? Adv Exp Med Biol 2005 0.76
84 Erratum to: Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes. Diabetologia 2015 0.75
85 Soluble interleukin-2 receptor alpha in preclinical type 1 diabetes. Acta Diabetol 2013 0.75