Published in J Am Soc Nephrol on March 17, 2011
Renal interstitial fibrosis: mechanisms and evaluation. Curr Opin Nephrol Hypertens (2012) 1.46
The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing. Int Orthop (2013) 1.00
Metalloproteinases in Drosophila to humans that are central players in developmental processes. J Biol Chem (2011) 0.97
Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. Hum Mol Genet (2014) 0.83
Transforming growth factor-β2 induces expression of biologically active bone morphogenetic protein-1 in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2013) 0.81
Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice. Int Orthop (2014) 0.81
Exogenous heparin binds and inhibits bone morphogenetic protein 6 biological activity. Int Orthop (2013) 0.80
Soluble biglycan as a biomarker of inflammatory renal diseases. Int J Biochem Cell Biol (2014) 0.80
Bone morphogenetic protein-1 processes insulin-like growth factor-binding protein 3. J Biol Chem (2011) 0.80
Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases. J Biol Chem (2012) 0.80
Tolloid-like proteinases orchestrate extracellular matrix formation. J Am Soc Nephrol (2011) 0.78
Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis. FASEB J (2016) 0.76
Current Therapeutic Approach to Hypertrophic Scars. Front Med (Lausanne) (2017) 0.75
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res (2001) 124.61
Novel regulators of bone formation: molecular clones and activities. Science (1988) 10.74
Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J Cell Biol (1997) 6.42
Negative regulation of transforming growth factor-beta by the proteoglycan decorin. Nature (1990) 4.90
Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int (2006) 4.87
Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1. Nature (1990) 4.64
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat Cell Biol (2002) 4.14
Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease. Nature (1992) 3.96
Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. Proc Natl Acad Sci U S A (2003) 2.66
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes (1996) 2.42
The bone morphogenetic protein 1/Tolloid-like metalloproteinases. Matrix Biol (2007) 2.27
BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein. J Cell Biol (2006) 2.17
Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development. J Biol Chem (1994) 2.03
IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy. Kidney Int (2006) 1.80
Decorin is a novel antagonistic ligand of the Met receptor. J Cell Biol (2009) 1.76
Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction. Nat Cell Biol (2008) 1.76
Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int (1999) 1.76
Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat. J Clin Invest (1998) 1.72
Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid. Development (1996) 1.65
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. Am J Pathol (2007) 1.58
Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction. Am J Pathol (2002) 1.52
Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption. J Biol Chem (2006) 1.45
Role of integrin-mediated TGFbeta activation in the pathogenesis of pulmonary fibrosis. Biochem Soc Trans (2009) 1.45
Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily. J Biol Chem (1990) 1.42
Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin. Proc Natl Acad Sci U S A (1989) 1.34
Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth. Cell Tissue Res (1999) 1.31
A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol (2009) 1.30
Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. J Biol Chem (2007) 1.28
Developmental roles of the BMP1/TLD metalloproteinases. Birth Defects Res C Embryo Today (2006) 1.28
Localization of osteogenic protein-1 (bone morphogenetic protein-7) during human embryonic development: high affinity binding to basement membranes. Biochem Biophys Res Commun (1994) 1.25
Loss of beta1 integrin in mouse fibroblasts results in resistance to skin scleroderma in a mouse model. Arthritis Rheum (2009) 1.25
Bone morphogenetic proteins in development and homeostasis of kidney. Cytokine Growth Factor Rev (2005) 1.24
Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int (1996) 1.19
Coordinated expression of beta 1 integrins and transforming growth factor-beta-induced matrix proteins in glomerulonephritis. Lab Invest (1993) 1.18
Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morphogenetic protein 7). Proc Natl Acad Sci U S A (1996) 1.17
Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro. J Cell Physiol (2000) 1.17
Role of EP2 and EP4 receptor-selective agonists of prostaglandin E(2) in acute and chronic kidney failure. Kidney Int (2006) 1.11
BMP-6 and mesenchymal stem cell differentiation. Cytokine Growth Factor Rev (2009) 1.07
Bone morphogenetic protein-7 and connective tissue growth factor: novel targets for treatment of renal fibrosis? Pharm Res (2008) 1.07
Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse development. J Histochem Cytochem (1995) 1.07
Folding and activity of recombinant human procollagen C-proteinase enhancer. Eur J Biochem (2001) 1.04
Integrins. Kidney Int Suppl (1994) 1.02
Myofibroblast progenitor cells are increased in number in patients with type 1 diabetes and express less bone morphogenetic protein 6: a novel clue to adverse tissue remodelling? Diabetologia (2006) 1.01
[On the evolution of endopeptidases, 3. A protease of molecular weight 11,000 and a trypsin-like fraction from Astacus fluviatilis fabr]. Hoppe Seylers Z Physiol Chem (1967) 1.00
Progressive renal disease: fibroblasts, extracellular matrix, and integrins. Exp Nephrol (1999) 1.00
Challenges for the present CKD classification system. Curr Opin Nephrol Hypertens (2010) 0.98
Bidirectional extracellular matrix signaling during tissue morphogenesis. Cytokine Growth Factor Rev (2009) 0.93
Decorin is processed by three isoforms of bone morphogenetic protein-1 (BMP1). Biochem Biophys Res Commun (2009) 0.93
Ex vivo transfer of the decorin gene into rat glomerulus via a mesangial cell vector suppressed extracellular matrix accumulation in experimental glomerulonephritis. Exp Mol Pathol (2005) 0.91
Bone morphogenetic protein 7: a novel treatment for chronic renal and bone disease. Curr Opin Nephrol Hypertens (2004) 0.91
Detection of bone and cartilage-related proteins in plasma of patients with a bone fracture using liquid chromatography-mass spectrometry. Int Orthop (2007) 0.89
Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4. J Biol Chem (2007) 0.88
Identification of amino acid residues in bone morphogenetic protein-1 important for procollagen C-proteinase activity. J Biol Chem (2001) 0.87
Collagen I upregulates extracellular matrix gene expression and secretion of TGF-beta 1 by cultured human mesangial cells. Am J Physiol Cell Physiol (2004) 0.86
Quantitative real time PCR of deoxycytidine kinase mRNA by Light Cycler PCR in relation to enzyme activity and gemcitabine sensitivity. Cancer Lett (2004) 0.85
Three alternatively spliced variants of the gene coding for the human bone morphogenetic protein-1. J Mol Med (Berl) (1998) 0.83
Urine release of systemically administered bone morphogenetic protein hybrid molecule. J Nephrol (2007) 0.83
Expression and role of integrin-linked kinase and collagen IV in human renal allografts with interstitial fibrosis and tubular atrophy. Transpl Immunol (2010) 0.78
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell (2006) 20.92
Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap. Mol Cell Proteomics (2005) 10.60
Lasofoxifene in postmenopausal women with osteoporosis. N Engl J Med (2010) 5.60
Higher-energy C-trap dissociation for peptide modification analysis. Nat Methods (2007) 5.04
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet (2009) 4.84
PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites. Genome Biol (2007) 4.66
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature (2011) 4.14
Metabolic priming by a secreted fungal effector. Nature (2011) 2.56
Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Mol Endocrinol (2003) 1.93
Efficacy of bazedoxifene in reducing new vertebral fracture risk in postmenopausal women with osteoporosis: results from a 3-year, randomized, placebo-, and active-controlled clinical trial. J Bone Miner Res (2008) 1.79
Breast cancer incidence in the randomized PEARL trial of lasofoxifene in postmenopausal osteoporotic women. J Natl Cancer Inst (2010) 1.79
Bacillus subtilis BY-kinase PtkA controls enzyme activity and localization of its protein substrates. Mol Microbiol (2010) 1.79
Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res (2008) 1.68
Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models. Genome Res (2010) 1.66
Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res (2007) 1.63
Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse. Mol Cell Proteomics (2013) 1.60
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. Am J Pathol (2007) 1.58
Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene (2002) 1.52
Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss. Proc Natl Acad Sci U S A (2008) 1.46
Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption. J Biol Chem (2006) 1.45
Fast-forward genetics identifies plant CPL phosphatases as regulators of miRNA processing factor HYL1. Cell (2012) 1.42
Proteomic analysis of the acid-soluble organic matrix of the chicken calcified eggshell layer. Proteomics (2006) 1.38
[Radiologic imaging of primary bone lymphoma--a retrospective study]. Lijec Vjesn (2006) 1.38
Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis. Proc Natl Acad Sci U S A (2007) 1.38
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. EMBO J (2011) 1.36
Thyroid-stimulating hormone restores bone volume, microarchitecture, and strength in aged ovariectomized rats. J Bone Miner Res (2007) 1.36
Bone morphogenetic protein-7 (osteogenic protein-1) promotes tendon graft integration in anterior cruciate ligament reconstruction in sheep. Am J Sports Med (2004) 1.31
RanGAP1 is a continuous marker of the Arabidopsis cell division plane. Proc Natl Acad Sci U S A (2008) 1.28
Biological aspects of bone, cartilage and tendon regeneration. Int Orthop (2007) 1.26
Bone morphogenetic proteins in development and homeostasis of kidney. Cytokine Growth Factor Rev (2005) 1.24
Stable isotope labeling by amino acids in cell culture (SILAC) applied to quantitative proteomics of Bacillus subtilis. J Proteome Res (2010) 1.23
Mass spectrometry at the interface of proteomics and genomics. Mol Biosyst (2010) 1.22
BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice. Gastroenterology (2010) 1.22
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice. Blood (2011) 1.19
Bacterial single-stranded DNA-binding proteins are phosphorylated on tyrosine. Nucleic Acids Res (2006) 1.19
The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals multiply phosphorylated proteins. Proteomics (2008) 1.18
Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast. Sci Signal (2011) 1.16
Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium. J Proteome Res (2013) 1.13
Expression of bone morphogenetic proteins and cartilage-derived morphogenetic proteins during osteophyte formation in humans. J Anat (2003) 1.12
Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response. Mol Cell Proteomics (2011) 1.12
Structural, immunocytochemical, and mr imaging properties of periventricular crossroads of growing cortical pathways in preterm infants. AJNR Am J Neuroradiol (2005) 1.11
Two distinct interacting classes of nuclear envelope-associated coiled-coil proteins are required for the tissue-specific nuclear envelope targeting of Arabidopsis RanGAP. Plant Cell (2008) 1.11
Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life. PLoS One (2009) 1.10
The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis. J Pharmacol Exp Ther (2010) 1.09
Bone morphogenetic protein-7 reduces the severity of colon tissue damage and accelerates the healing of inflammatory bowel disease in rats. J Cell Physiol (2003) 1.08
A novel, non-prostanoid EP2 receptor-selective prostaglandin E2 agonist stimulates local bone formation and enhances fracture healing. J Bone Miner Res (2003) 1.07
C-mannosylation and o-fucosylation of thrombospondin type 1 repeats. Mol Cell Proteomics (2002) 1.06
MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes. Nucleic Acids Res (2006) 1.06
Deep coverage of the Escherichia coli proteome enables the assessment of false discovery rates in simple proteogenomic experiments. Mol Cell Proteomics (2013) 1.05
Bone morphogenetic proteins: from developmental signals to tissue regeneration. Conference on bone morphogenetic proteins. EMBO Rep (2007) 1.03
Phosphoproteins of the chicken eggshell calcified layer. Proteomics (2007) 1.02
Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity. J Biol Chem (2010) 1.01
Ten-year experience with sevelamer and calcium salts as phosphate binders. Clin J Am Soc Nephrol (2010) 1.01
The nuclear pore and plant development. Curr Opin Plant Biol (2008) 1.01
Do guidelines for the diagnosis and monitoring of diabetes mellitus fulfill the criteria of evidence-based guideline development? Clin Chem (2008) 1.01
Impact of phosphoproteomics on studies of bacterial physiology. FEMS Microbiol Rev (2011) 1.01
The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing. Int Orthop (2013) 1.00
The EC4 European syllabus for post-graduate training in clinical chemistry and laboratory medicine: version 4--2012. Clin Chem Lab Med (2012) 0.99
Proteome analysis of erythrocytes lacking AMP-activated protein kinase reveals a role of PAK2 kinase in eryptosis. J Proteome Res (2011) 0.98
Activation of Bacillus subtilis Ugd by the BY-kinase PtkA proceeds via phosphorylation of its residue tyrosine 70. J Mol Microbiol Biotechnol (2009) 0.97
Mechanism-based pharmacokinetic/pharmacodynamic model of parathyroid hormone-calcium homeostasis in rats and humans. J Pharmacol Exp Ther (2009) 0.96
Protein kinase CK1α regulates erythrocyte survival. Cell Physiol Biochem (2012) 0.96
Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO J (2012) 0.96
Phosphorylation of SUMO-1 occurs in vivo and is conserved through evolution. J Proteome Res (2008) 0.96
A nonprostanoid EP4 receptor selective prostaglandin E2 agonist restores bone mass and strength in aged, ovariectomized rats. J Bone Miner Res (2006) 0.95
High accuracy mass spectrometry in large-scale analysis of protein phosphorylation. Methods Mol Biol (2009) 0.95
Dysregulated expression of MIC-1/PDF in human prostate tumor cells. Biochem Biophys Res Commun (2003) 0.95
Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells. Mol Cell Proteomics (2012) 0.95
Adding pieces to the puzzling plant nuclear envelope. Curr Opin Plant Biol (2009) 0.93
Biological aspects of segmental bone defects management. Int Orthop (2015) 0.93
Proteomics reveals evidence of cross-talk between protein modifications in bacteria: focus on acetylation and phosphorylation. Curr Opin Microbiol (2012) 0.92
Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments. Nat Methods (2013) 0.92
Prevalence of HBV genotypes in Central and Eastern Europe. J Med Virol (2008) 0.92
Small molecule inhibitors of IkappaB kinase signaling inhibit osteoclast formation in vitro and prevent ovariectomy-induced bone loss in vivo. FASEB J (2010) 0.91
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality. PLoS One (2013) 0.91
Treatment of a congenital pseudarthrosis of the tibia by osteogenic protein-1 (bone morphogenetic protein-7): a case report. J Pediatr Orthop B (2006) 0.91
Thoracoabdominal and coronary arterial aneurysms in a young man with a history of Kawasaki disease. J Vasc Surg (2009) 0.90
The discovery of novel calcium sensing receptor negative allosteric modulators. Bioorg Med Chem Lett (2009) 0.90
The neuropeptide complement of the marine annelid Platynereis dumerilii. BMC Genomics (2013) 0.90
Detection of bone and cartilage-related proteins in plasma of patients with a bone fracture using liquid chromatography-mass spectrometry. Int Orthop (2007) 0.89
Ureteral metastasis as the first and sole manifestation of gastric cancer dissemination. Radiol Oncol (2010) 0.88
Left ventricular fibroma mimicking an acute coronary syndrome. Ann Thorac Surg (2006) 0.88
NetPhosBac - a predictor for Ser/Thr phosphorylation sites in bacterial proteins. Proteomics (2009) 0.88
Interpretation and management of INR results: a case history based survey in 13 countries. Thromb Res (2012) 0.88
Requirement of a bone morphogenetic protein for the maintenance and stimulation of osteoblast differentiation. Arch Histol Cytol (2006) 0.88
Acute interstitial nephritis due to mesalazine. Nephrology (Carlton) (2005) 0.87
Toward quantitative proteomics of organ substructures: implications for renal physiology. Semin Nephrol (2010) 0.87
Phosphorylation of Ser 402 impedes phosphatase activity of slingshot 1. EMBO Rep (2011) 0.87
Imaging bone morphogenetic protein 7 induced cell cycle arrest in experimental gliomas. Neoplasia (2011) 0.87
Malposition of central venous dialysis catheter in the right internal mammary vein in uremic patient: case report. Acta Clin Croat (2011) 0.86
Extending SILAC to proteomics of plant cell lines. Plant Cell (2011) 0.85
Bone morphogenetic protein 7 inhibits tumor growth of human uveal melanoma in vivo. Invest Ophthalmol Vis Sci (2007) 0.85
Bone morphogenetic protein (BMP)1-3 enhances bone repair. Biochem Biophys Res Commun (2011) 0.84
GIT1 phosphorylation on serine 46 by PKD3 regulates paxillin trafficking and cellular protrusive activity. J Biol Chem (2012) 0.84