Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMC 3085744)

Published in Curr Atheroscler Rep on June 01, 2011

Authors

Wijtske Annema1, Uwe J F Tietge

Author Affiliations

1: Department of Pediatrics, Center for Liver, Digestive, and Metabolic Diseases, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands. w.annema@med.umcg.nl

Articles citing this

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. Circulation (2012) 3.38

Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations. PLoS Genet (2012) 1.31

Crosstalk between reverse cholesterol transport and innate immunity. Trends Endocrinol Metab (2012) 1.04

The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype. Biochim Biophys Acta (2011) 1.03

GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm. PLoS Genet (2013) 1.03

Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies. Nutr Metab (Lond) (2012) 0.90

Functionally defective high-density lipoprotein and paraoxonase: a couple for endothelial dysfunction in atherosclerosis. Cholesterol (2013) 0.90

The endothelial lipase protein is promising urinary biomarker for diagnosis of gastric cancer. Diagn Pathol (2013) 0.84

Down-regulation of lipoprotein lipase increases ABCA1-mediated cholesterol efflux in THP-1 macrophages. Biochem Biophys Res Commun (2014) 0.84

Effects and Potential Mechanisms of Pioglitazone on Lipid Metabolism in Obese Diabetic KKAy Mice. PPAR Res (2014) 0.83

Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response. Lipids Health Dis (2011) 0.83

LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells. PLoS One (2013) 0.79

Regulation of hepatic lipase activity by sphingomyelin in plasma lipoproteins. Biochim Biophys Acta (2015) 0.79

Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism. PLoS One (2013) 0.78

Insulin Clearance Is Associated with Hepatic Lipase Activity and Lipid and Adiposity Traits in Mexican Americans. PLoS One (2016) 0.75

Advances in the Study of the Antiatherogenic Function and Novel Therapies for HDL. Int J Mol Sci (2015) 0.75

Lycopene stabilizes lipoprotein levels during D-galactosamine/lipopolysaccharide induced hepatitis in experimental rats. Asian Pac J Trop Biomed (2012) 0.75

Reference ranges of cholesterol sub-fractions in random healthy adults in Ouagadougou, Burkina Faso. PLoS One (2015) 0.75

A computational model for the analysis of lipoprotein distributions in the mouse: translating FPLC profiles to lipoprotein metabolism. PLoS Comput Biol (2014) 0.75

Impact of Endothelial Lipase on Cholesterol Efflux Capacity of Serum and High-density Lipoprotein. Sci Rep (2017) 0.75

Articles cited by this

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet (2005) 32.41

New insights into the regulation of HDL metabolism and reverse cholesterol transport. Circ Res (2005) 4.47

A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet (1999) 2.56

Cloning of a unique lipase from endothelial cells extends the lipase gene family. J Biol Chem (1999) 2.19

Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study. Stroke (2002) 2.06

Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest (2009) 1.83

Hepatic proprotein convertases modulate HDL metabolism. Cell Metab (2007) 1.68

The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis. J Clin Endocrinol Metab (2004) 1.60

Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. J Biol Chem (2004) 1.54

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis. PLoS Med (2005) 1.52

Hepatic lipase mutations,elevated high-density lipoprotein cholesterol, and increased risk of ischemic heart disease: the Copenhagen City Heart Study. J Am Coll Cardiol (2003) 1.50

Hepatic lipase, lipoprotein metabolism, and atherogenesis. Arterioscler Thromb Vasc Biol (2004) 1.49

Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease. J Clin Endocrinol Metab (2008) 1.46

Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics. Arterioscler Thromb (1993) 1.45

Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase. Circulation (2003) 1.38

Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-/- and LDLR-/- mice. J Lipid Res (2005) 1.35

Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis. Circ J (2010) 1.26

High-density lipoprotein-cholesterol, its subfractions, and responses to exercise training are dependent on endothelial lipase genotype. Metabolism (2003) 1.19

In vivo modulation of HDL phospholipid has opposing effects on SR-BI- and ABCA1-mediated cholesterol efflux. J Lipid Res (2003) 1.14

Relationship between serum HDL-C levels and common genetic variants of the endothelial lipase gene in Japanese school-aged children. Hum Genet (2003) 1.13

Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels. Biochim Biophys Acta (2004) 1.12

Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice. J Biol Chem (1997) 1.12

Scavenger receptor BI-mediated selective uptake is required for the remodeling of high density lipoprotein by endothelial lipase. J Biol Chem (2009) 1.12

The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. Eur Heart J (2009) 1.08

Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity. Biochem J (2002) 1.05

Protective effect of an endothelial lipase gene variant on coronary artery disease in a Chinese population. J Lipid Res (2007) 1.05

Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice. J Lipid Res (2009) 1.05

The T111I mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women. J Lipid Res (2003) 1.02

Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins. Circ Res (2010) 1.00

Low hepatic lipase activity is a novel risk factor for coronary artery disease. Circulation (2001) 1.00

Endothelial lipase gene polymorphism is associated with acute myocardial infarction, independently of high-density lipoprotein-cholesterol levels. Circ J (2007) 0.99

A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis. J Lipid Res (2009) 0.97

Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice. J Clin Invest (2003) 0.95

Endothelial lipase promotes apolipoprotein AI-mediated cholesterol efflux in THP-1 macrophages. Arterioscler Thromb Vasc Biol (2008) 0.93

Hepatic lipase gene -514 C/T polymorphism and premature coronary heart disease. J Cardiovasc Risk (2002) 0.93

Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mice. J Lipid Res (2006) 0.91

Lipases and HDL metabolism. Trends Endocrinol Metab (2002) 0.91

Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT. Atherosclerosis (2010) 0.90

Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism. J Lipid Res (2004) 0.89

Hepatic lipase deficiency delays atherosclerosis, myocardial infarction, and cardiac dysfunction and extends lifespan in SR-BI/apolipoprotein E double knockout mice. Arterioscler Thromb Vasc Biol (2006) 0.88

Endothelial lipase-modified high-density lipoprotein exhibits diminished ability to mediate SR-BI (scavenger receptor B type I)-dependent free-cholesterol efflux. Biochem J (2004) 0.87

Combined hyperlipidemia/hyperalphalipoproteinemia associated with premature spontaneous atherosclerosis in mice lacking hepatic lipase and low density lipoprotein receptor. Atherosclerosis (2005) 0.87

Hepatic lipase (LIPC) promoter polymorphism in men with coronary artery disease. Allele frequency and effects on hepatic lipase activity and plasma HDL-C concentrations. Arterioscler Thromb Vasc Biol (1999) 0.87

The bridging function of hepatic lipase clears plasma cholesterol in LDL receptor-deficient "apoB-48-only" and "apoB-100-only" mice. J Lipid Res (2003) 0.86

Putative role of endothelial lipase in dialysis patients with hypoalbuminemia and inflammation. Am J Nephrol (2008) 0.85

The hepatic lipase gene C-480T polymorphism in the development of early coronary atherosclerosis: the Helsinki Sudden Death Study. Eur J Clin Invest (2007) 0.84

Increased type IIA secretory phospholipase A(2) expression contributes to oxidative stress in end-stage renal disease. J Mol Med (Berl) (2009) 0.81

Reduced atherosclerosis in chow-fed mice expressing high levels of a catalytically inactive human hepatic lipase. Atherosclerosis (2007) 0.81

Leukocyte-derived hepatic lipase increases HDL and decreases en face aortic atherosclerosis in LDLr-/- mice expressing CETP. J Lipid Res (2008) 0.79

Biliary lipid secretion, bile acid metabolism, and gallstone formation are not impaired in hepatic lipase-deficient mice. Hepatology (2003) 0.78

Articles by these authors

Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol. J Biol Chem (2009) 1.71

Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis. Circulation (2004) 1.69

High fat feeding induces hepatic fatty acid elongation in mice. PLoS One (2009) 1.51

The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism. Cell Metab (2014) 1.47

Dose-dependent acceleration of high-density lipoprotein catabolism by endothelial lipase. Circulation (2003) 1.38

Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A(2). J Lipid Res (2010) 1.35

Transsignaling of interleukin-6 crucially contributes to atherosclerosis in mice. Arterioscler Thromb Vasc Biol (2011) 1.29

Chemokine receptor 7 knockout attenuates atherosclerotic plaque development. Circulation (2010) 1.24

Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice. Hepatology (2009) 1.20

Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production. J Lipid Res (2006) 1.20

Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice. Gastroenterology (2010) 1.16

Liver transplantation improves hepatic myelopathy: evidence by three cases. Gastroenterology (2003) 1.14

Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice. Circ Res (2007) 1.12

Scavenger receptor BI-mediated selective uptake is required for the remodeling of high density lipoprotein by endothelial lipase. J Biol Chem (2009) 1.12

High-density lipoprotein loses its anti-inflammatory capacity by accumulation of pro-inflammatory-serum amyloid A. Cardiovasc Res (2012) 1.11

P2Y13 receptor is critical for reverse cholesterol transport. Hepatology (2010) 1.11

Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice. J Lipid Res (2009) 1.05

Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice. Hepatology (2008) 1.04

High-resolution imaging of human atherosclerotic carotid plaques with micro 18F-FDG PET scanning exploring plaque vulnerability. J Nucl Cardiol (2011) 1.01

Scavenger receptor BI facilitates hepatic very low density lipoprotein production in mice. J Lipid Res (2009) 1.00

Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a]. J Lipid Res (2005) 0.98

Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man. J Exp Med (2007) 0.97

Pro-atherogenic lipid changes and decreased hepatic LDL receptor expression by tocilizumab in rheumatoid arthritis. Atherosclerosis (2013) 0.97

Assessing the functional properties of high-density lipoproteins: an emerging concept in cardiovascular research. Biomark Med (2013) 0.96

Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice. Hepatology (2013) 0.96

Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet. Atherosclerosis (2009) 0.94

Pancreatic β-cell function relates positively to HDL functionality in well-controlled type 2 diabetes mellitus. Atherosclerosis (2012) 0.92

Plasma levels of PBEF/Nampt/visfatin are decreased in patients with liver cirrhosis. Am J Physiol Gastrointest Liver Physiol (2008) 0.91

Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL. Arterioscler Thromb Vasc Biol (2007) 0.91

Combined effects of HMG-CoA-reductase inhibition and renin-angiotensin system blockade on experimental atherosclerosis. Atherosclerosis (2005) 0.89

ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma. J Lipid Res (2012) 0.89

Voluntary wheel running increases bile acid as well as cholesterol excretion and decreases atherosclerosis in hypercholesterolemic mice. Atherosclerosis (2011) 0.89

Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice. Biochim Biophys Acta (2011) 0.88

Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis. Biochim Biophys Acta (2013) 0.87

Elevated resistin levels in cirrhosis are associated with the proinflammatory state and altered hepatic glucose metabolism but not with insulin resistance. Am J Physiol Endocrinol Metab (2006) 0.87

Decreased hepatic RBP4 secretion is correlated with reduced hepatic glucose production but is not associated with insulin resistance in patients with liver cirrhosis. Clin Endocrinol (Oxf) (2008) 0.87

Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein. J Lipid Res (2006) 0.86

Simvastatin and bezafibrate increase cholesterol efflux in men with type 2 diabetes. Eur J Clin Invest (2014) 0.85

Increased LCAT activity and hyperglycaemia decrease the antioxidative functionality of HDL. Eur J Clin Invest (2011) 0.85

Skin autofluorescence is inversely related to HDL anti-oxidative capacity in type 2 diabetes mellitus. Atherosclerosis (2011) 0.85

Plasma bile acids are associated with energy expenditure and thyroid function in humans. J Clin Endocrinol Metab (2011) 0.85

Role the TICE?: advancing the concept of transintestinal cholesterol excretion. Arterioscler Thromb Vasc Biol (2013) 0.85

Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI: role of negatively charged phospholipids. Atherosclerosis (2011) 0.85

Gremlin-1 is an inhibitor of macrophage migration inhibitory factor and attenuates atherosclerotic plaque growth in ApoE-/- Mice. J Biol Chem (2013) 0.84

Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice. J Lipid Res (2013) 0.83

Low normal free T4 confers decreased high-density lipoprotein antioxidative functionality in the context of hyperglycaemia. Clin Endocrinol (Oxf) (2013) 0.83

Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice. J Lipid Res (2011) 0.83

Differential impact of hepatic deficiency and total body inhibition of MTP on cholesterol metabolism and RCT in mice. J Lipid Res (2014) 0.83

Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice. J Lipid Res (2013) 0.82

Increased type IIA secretory phospholipase A(2) expression contributes to oxidative stress in end-stage renal disease. J Mol Med (Berl) (2009) 0.81

Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis. Front Biosci (Landmark Ed) (2009) 0.81

The inverse relation of HDL anti-oxidative functionality with serum amyloid a is lost in metabolic syndrome subjects. Obesity (Silver Spring) (2013) 0.81

Cholesterol efflux and reverse cholesterol transport. Handb Exp Pharmacol (2015) 0.80

Altered apolipoprotein A-V expression during the acute phase response is independent of plasma triglyceride levels in mice and humans. Biochem Biophys Res Commun (2005) 0.80

Liver transplantation in a subject with familial hypercholesterolemia carrying the homozygous p.W577R LDL-receptor gene mutation. Clin Transplant (2008) 0.80

Human luteinized granulosa cells secrete apoB100-containing lipoproteins. J Lipid Res (2010) 0.80

Elastosis perforans serpiginosa secondary to D-penicillamine treatment in a Wilson's disease patient. Am J Gastroenterol (2002) 0.79

Activated platelets contribute to oxidized low-density lipoproteins and dysfunctional high-density lipoproteins through a phospholipase A2-dependent mechanism. FASEB J (2011) 0.79

Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice. PLoS One (2013) 0.79

Recurrence of Budd-Chiari syndrome after liver transplantation in paroxysmal nocturnal hemoglobinuria. Transpl Int (2003) 0.78

rHDL administration increases reverse cholesterol transport in mice, but is not additive on top of ezetimibe or cholestyramine treatment. Atherosclerosis (2013) 0.78

The eye in Wilson's disease: sunflower cataract associated with Kayser-Fleischer ring. J Hepatol (2002) 0.78

Angiotensin II type 1-receptor antagonism prevents type IIA secretory phospholipase A2-dependent lipid peroxidation. Atherosclerosis (2006) 0.77

Role of suppressor of cytokine signaling-1 in murine atherosclerosis. PLoS One (2012) 0.77

The neglected cousin of the hepatocyte: how gallbladder epithelial cells might contribute to cholesterol gallstone formation. Dig Dis Sci (2013) 0.76

Expression of type IIA secretory phospholipase A2 inhibits cholesteryl ester transfer protein activity in transgenic mice. Arterioscler Thromb Vasc Biol (2013) 0.76

In vivo fluorescence-mediated tomography imaging demonstrates atorvastatin-mediated reduction of lesion macrophages in ApoE-/- mice. Anesthesiology (2013) 0.76

Serum bile acids and leptin interact with glucose metabolism in patients with liver cirrhosis. Clin Nutr (2012) 0.76

Reduced plasma adiponectin in NASH: central obesity as an underestimated causative risk factor. Hepatology (2005) 0.75

Winner by points?--LDL cholesterol as a target for therapeutic intervention. Curr Opin Lipidol (2013) 0.75