Published in ACS Comb Sci on March 25, 2011
Intramolecular monomer-on-monomer (MoM) Mitsunobu cyclization for the synthesis of benzofused thiadiazepine-dioxides. Chem Commun (Camb) (2011) 0.81
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med (2013) 3.10
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix. Cell Metab (2011) 1.87
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicity. J Chem Inf Model (2010) 1.68
Mitochondria-targeted small molecule therapeutics and probes. Antioxid Redox Signal (2011) 1.66
Mitochondrial pharmacology. Trends Pharmacol Sci (2012) 1.51
Are carotenoids a red herring in sexual display? Trends Ecol Evol (2004) 1.13
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration. Bioorg Med Chem Lett (2009) 1.10
Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nat Protoc (2012) 1.04
Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. J Am Chem Soc (2011) 0.98
Titanium reagents for the synthesis of 2-substituted benzo[b]thiophenes on the solid phase. J Org Chem (2004) 0.94
Using exomarkers to assess mitochondrial reactive species in vivo. Biochim Biophys Acta (2013) 0.94
In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice. Aging Cell (2014) 0.93
Synthesis of 2-substituted benzofurans and indoles using functionalized titanium benzylidene reagents on solid phase. J Org Chem (2003) 0.92
Development of a new EPR spin trap, DOD-8C (N-[4-dodecyloxy-2-(7'-carboxyhept-1'-yloxy)benzylidene]-N-tert-butylamine N-oxide), for the trapping of lipid radicals at a predetermined depth within biological membranes. Arch Biochem Biophys (2005) 0.90
Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4'-glucoside. J Agric Food Chem (2002) 0.90
Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy. J Agric Food Chem (2003) 0.89
Reaction between peroxynitrite and triphenylphosphonium-substituted arylboronic acid isomers: identification of diagnostic marker products and biological implications. Chem Res Toxicol (2013) 0.86
Potential therapeutic antioxidants that combine the radical scavenging ability of myricetin and the lipophilic chain of vitamin E to effectively inhibit microsomal lipid peroxidation. Bioorg Med Chem (2004) 0.85
Nitrones for understanding and ameliorating the oxidative stress associated with aging. Age (Dordr) (2009) 0.84
Beta-amino acids to piperidinones by Petasis methylenation and acid-induced cyclization. J Org Chem (2007) 0.83
Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors. Bioorg Med Chem Lett (2008) 0.83
Synthesis of a mitochondria-targeted spin trap using a novel Parham-type cyclization. Tetrahedron (2009) 0.83
Synthesis and structure-activity relationships of indazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists. J Med Chem (2013) 0.82
Bioavailability of [2-(14)C]quercetin-4'-glucoside in rats. J Agric Food Chem (2008) 0.82
Caged mitochondrial uncouplers that are released in response to hydrogen peroxide. Tetrahedron (2010) 0.82
A dual sensor spin trap for use with EPR spectroscopy. Org Lett (2007) 0.82
N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: indazoles as phenol isosteres with improved pharmacokinetics. Bioorg Med Chem Lett (2007) 0.81
Synthesis of N-arylpyridinium salts bearing a nitrone spin trap as potential mitochondria-targeted antioxidants. Tetrahedron (2009) 0.81
A prototypical small-molecule modulator uncouples mitochondria in response to endogenous hydrogen peroxide production. Chembiochem (2013) 0.80
The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis. J Med Chem (2011) 0.80
Optimized chemical probes for REV-ERBα. J Med Chem (2013) 0.79
Disposition and metabolism of [2-14C]quercetin-4'-glucoside in rats. Drug Metab Dispos (2005) 0.79
Synthesis and pharmacological investigation of azaphthalazinone human histamine H(1) receptor antagonists. Bioorg Med Chem (2012) 0.79
Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease. J Med Chem (2016) 0.78
Targeting mitochondria with small molecules: the preparation of MitoB and MitoP as exomarkers of mitochondrial hydrogen peroxide. Methods Mol Biol (2015) 0.78
Low molecular weight MPEG-assisted organic synthesis. Chem Commun (Camb) (2010) 0.78
Absorption, disposition, metabolism, and excretion of [3-(14)C]caffeic acid in rats. J Agric Food Chem (2012) 0.77
Novel functionalized titanium(IV) benzylidenes for the traceless solid-phase synthesis of indoles. Org Lett (2002) 0.77
Analysis of neighborhood behavior in lead optimization and array design. J Chem Inf Model (2009) 0.77
Detection and identification of 14C-labelled flavonol metabolites by high-performance liquid chromatography-radiocounting and tandem mass spectrometry. J Chromatogr A (2003) 0.76
A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance. Behav Brain Res (2012) 0.76
Expanding the palette of phenanthridinium cations. Chemistry (2014) 0.75
Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis. Org Biomol Chem (2016) 0.75
Boronate titanium alkylidene reagents for diversity-based synthesis of benzofurans. Org Lett (2003) 0.75
A practical drug discovery project at the undergraduate level. Drug Discov Today (2013) 0.75
Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease. J Med Chem (2016) 0.75
Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity. Bioorg Med Chem Lett (2010) 0.75