Published in Steroids on April 02, 2011
Metabolic Coupling Determines the Activity: Comparison of 11β-Hydroxysteroid Dehydrogenase 1 and Its Coupling between Liver Parenchymal Cells and Testicular Leydig Cells. PLoS One (2015) 0.75
Corticosterone metabolism by chicken follicle cells does not affect ovarian reproductive hormone synthesis in vitro. Gen Comp Endocrinol (2013) 0.75
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling. Circulation (2006) 2.55
FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases. Proc Natl Acad Sci U S A (2007) 2.08
Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells. Endocrinology (2003) 1.81
In search of rat stem Leydig cells: identification, isolation, and lineage-specific development. Proc Natl Acad Sci U S A (2006) 1.79
A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk. Sci Transl Med (2014) 1.39
Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances. Proc Natl Acad Sci U S A (2004) 1.35
Leydig cells: From stem cells to aging. Mol Cell Endocrinol (2009) 1.32
Phthalate levels and low birth weight: a nested case-control study of Chinese newborns. J Pediatr (2009) 1.30
Phthalate ester toxicity in Leydig cells: developmental timing and dosage considerations. Reprod Toxicol (2007) 1.24
Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell. Endocrinology (2003) 1.17
Gene expression in rat leydig cells during development from the progenitor to adult stage: a cluster analysis. Biol Reprod (2005) 1.15
Biphasic effects of postnatal exposure to diethylhexylphthalate on the timing of puberty in male rats. J Androl (2007) 1.11
Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero. Proc Natl Acad Sci U S A (2008) 1.09
Effects of insulin-like growth factor I on steroidogenic enzyme expression levels in mouse leydig cells. Endocrinology (2003) 1.08
Trends of reproductive hormones in male rats during psychosocial stress: role of glucocorticoid metabolism in behavioral dominance. Biol Reprod (2002) 1.07
11{beta}-Hydroxysteroid dehydrogenase 2 in rat leydig cells: its role in blunting glucocorticoid action at physiological levels of substrate. Endocrinology (2005) 1.05
Development of leydig cells in the insulin-like growth factor-I (igf-I) knockout mouse: effects of igf-I replacement and gonadotropic stimulation. Biol Reprod (2003) 1.05
Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence. Trends Endocrinol Metab (2009) 1.03
Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress. J Androl (2004) 1.01
Identification, proliferation, and differentiation of adult Leydig stem cells. Endocrinology (2012) 1.01
Glucocorticoid induces apoptosis in rat leydig cells. Endocrinology (2002) 0.96
Inhibitors of testosterone biosynthetic and metabolic activation enzymes. Molecules (2011) 0.95
Role of systemic and local IGF-I in the effects of estrogen on growth and epithelial proliferation of mouse uterus. Endocrinology (2002) 0.95
Adenovirus type 5 pseudotyped with adenovirus type 37 fiber uses sialic acid as a cellular receptor. Virology (2004) 0.93
Intercellular trafficking of adenovirus-delivered HSV VP22 from the retinal pigment epithelium to the photoreceptors--implications for gene therapy. Mol Ther (2002) 0.92
Age-related decreases in Leydig cell testosterone production are not restored by exposure to LH in vitro. Endocrinology (2002) 0.92
In utero and lactational exposures to diethylhexyl-phthalate affect two populations of Leydig cells in male Long-Evans rats. Biol Reprod (2009) 0.92
The (+)- and (-)-gossypols potently inhibit both 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 in human and rat testes. J Steroid Biochem Mol Biol (2009) 0.91
Inhibition of human and rat testicular steroidogenic enzyme activities by bisphenol A. Toxicol Lett (2011) 0.91
Hydrogen generation from formic acid and alcohols using homogeneous catalysts. Chem Soc Rev (2009) 0.90
Paracrine modulation of androgen synthesis in rat leydig cells by nitric oxide. J Androl (2005) 0.90
Characterization of a novel gain of function glucocorticoid receptor knock-in mouse. J Biol Chem (2008) 0.90
Comparison of cell types in the rat Leydig cell lineage after ethane dimethanesulfonate treatment. Reproduction (2013) 0.90
Evidence of protein transduction but not intercellular transport by proteins fused to HIV tat in retinal cell culture and in vivo. Mol Ther (2003) 0.90
Stem Leydig cell differentiation: gene expression during development of the adult rat population of Leydig cells. Biol Reprod (2011) 0.89
Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome. Med Hypotheses (2009) 0.89
A role for kit receptor signaling in Leydig cell steroidogenesis. Biol Reprod (2003) 0.89
Altered prostatic epithelial proliferation and apoptosis, prostatic development, and serum testosterone in mice lacking cyclin-dependent kinase inhibitors. Biol Reprod (2005) 0.89
Deletion of the Igf1 gene: suppressive effects on adult Leydig cell development. J Androl (2010) 0.89
Mono-(2-ethylhexyl) phthalate affects the steroidogenesis in rat Leydig cells through provoking ROS perturbation. Toxicol In Vitro (2012) 0.89
Environmental inhibitors of 11β-hydroxysteroid dehydrogenase type 2. Toxicology (2011) 0.88
Gene expression during development of fetal and adult Leydig cells. Ann N Y Acad Sci (2007) 0.87
Myxobolus albi n. sp. (Myxozoa) from the Gills of the Common Goby Pomatoschistus microps Krøyer (Teleostei: Gobiidae). J Eukaryot Microbiol (2009) 0.86
Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated. Mol Cell Endocrinol (2005) 0.86
The inhibition of human and rat 11β-hydroxysteroid dehydrogenase 2 by perfluoroalkylated substances. J Steroid Biochem Mol Biol (2011) 0.86
The role of the Leydig cell in spermatogenic function. Adv Exp Med Biol (2008) 0.86
Kit ligand cytoplasmic domain is essential for basolateral sorting in vivo and has roles in spermatogenesis and hematopoiesis. Dev Biol (2009) 0.86
Direct fibrogenic effects of aldosterone on normotensive kidney: an effect modified by 11β-HSD activity. Am J Physiol Renal Physiol (2010) 0.85
Morphological and proteomic analysis of early stage of osteoblast differentiation in osteoblastic progenitor cells. Exp Cell Res (2010) 0.85
11 beta-Hydroxysteroid dehydrogenase antisense affects vascular contractile response and glucocorticoid metabolism. Steroids (2002) 0.85
Inhibition of recovery of spermatogenesis in irradiated rats by different androgens. Endocrinology (2002) 0.84
Expression of 11beta-hydroxylase in rat Leydig cells. Endocrinology (2002) 0.84
Testosterone production in the aging male: where does the slowdown occur? Endocrinology (2004) 0.84
Testosterone production in mice lacking inducible nitric oxide synthase expression is sensitive to restraint stress. Am J Physiol Endocrinol Metab (2006) 0.83
Characterization of murine interferon-alpha 12 (MuIFN-alpha12): biological activities and gene expression. Cytokine (2007) 0.83
Parting messages from current and former editors of the Journal of Andrology. J Androl (2012) 0.83
Structure-dependent inhibition of human and rat 11beta-hydroxysteroid dehydrogenase 2 activities by phthalates. Chem Biol Interact (2010) 0.83
Mechanisms of glucocorticoid-induced Leydig cell apoptosis. Mol Cell Endocrinol (2003) 0.83
Rapid mechanisms of glucocorticoid signaling in the Leydig cell. Steroids (2007) 0.83
Human renal 11beta-hydroxysteroid dehydrogenase 1 functions and co-localizes with COX-2. Life Sci (2008) 0.83
Glucocorticoid suppresses steroidogenesis in rat progenitor Leydig cells. J Androl (2010) 0.82
Androgen-forming stem Leydig cells: identification, function and therapeutic potential. Dis Markers (2008) 0.82
Effects of phthalates on 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase 3 activities in human and rat testes. Chem Biol Interact (2011) 0.82
Curcumin as a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase 1: improving lipid profiles in high-fat-diet-treated rats. PLoS One (2013) 0.82
Adjudin targeting rabbit germ cell adhesion as a male contraceptive: a pharmacokinetics study. J Androl (2008) 0.82
Müllerian-inhibiting substance inhibits rat Leydig cell regeneration after ethylene dimethanesulphonate ablation. Biol Reprod (2003) 0.81
Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms in vascular endothelial cells. Steroids (2008) 0.81
Development of Tetracapsuloides bryosalmonae (Myxozoa: Malacosporea) in bryozoan hosts (as examined by light microscopy) and quantitation of infective dose to rainbow trout (Oncorhynchus mykiss). Vet Parasitol (2005) 0.81
Endogenous selective inhibitors of 11beta-hydroxysteroid dehydrogenase isoforms 1 and 2 of adrenal origin. Mol Cell Endocrinol (2005) 0.80
Dihydrolipoamide dehydrogenase and cAMP are associated with cadmium-mediated Leydig cell damage. Toxicol Lett (2011) 0.80
The biological roles of extracellular and intracytoplasmic glucocorticoids in skeletal cells. J Steroid Biochem Mol Biol (2008) 0.80
Increased proliferation but decreased steroidogenic capacity in Leydig cells from mice lacking cyclin-dependent kinase inhibitor 1B. Biol Reprod (2009) 0.80
Inhibition of 3beta- and 17beta-hydroxysteroid dehydrogenase activities in rat Leydig cells by perfluorooctane acid. J Steroid Biochem Mol Biol (2009) 0.80
Inhibition of 11beta-hydroxysteroid dehydrogenase enzymatic activities by glycyrrhetinic acid in vivo supports direct glucocorticoid-mediated suppression of steroidogenesis in Leydig cells. J Androl (2008) 0.80
Effects of luteinizing hormone and androgen on the development of rat progenitor Leydig cells in vitro and in vivo. Asian J Androl (2013) 0.80