Published in J Androl on March 25, 2011
Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling. Antioxid Redox Signal (2013) 1.48
Why are epididymal tumours so rare? Asian J Androl (2012) 0.95
Utility of antioxidants during assisted reproductive techniques: an evidence based review. Reprod Biol Endocrinol (2014) 0.80
Recent knowledge concerning mammalian sperm chromatin organization and its potential weaknesses when facing oxidative challenge. Basic Clin Androl (2014) 0.80
Epididymis response partly compensates for spermatozoa oxidative defects in snGPx4 and GPx5 double mutant mice. PLoS One (2012) 0.79
Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility. Sci Rep (2016) 0.75
Chronic Water-Pipe Smoke Exposure Induces Injurious Effects to Reproductive System in Male Mice. Front Physiol (2017) 0.75
Glutathione Peroxidase 5 Is Expressed by the Entire Pig Male Genital Tract and Once in the Seminal Plasma Contributes to Sperm Survival and In Vivo Fertility. PLoS One (2016) 0.75
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death. Cell Metab (2008) 3.52
Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development. Mol Cell Biol (2005) 1.80
Role of the mammalian RNA polymerase II C-terminal domain (CTD) nonconsensus repeats in CTD stability and cell proliferation. Mol Cell Biol (2005) 1.55
Dietary cholesterol-induced post-testicular infertility. PLoS One (2011) 1.47
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration. FASEB J (2009) 1.41
Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities. Eur J Biochem (2002) 1.39
EpCAM is involved in maintenance of the murine embryonic stem cell phenotype. Stem Cells (2009) 1.31
Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate. Genesis (2007) 1.23
Lipid remodeling of murine epididymosomes and spermatozoa during epididymal maturation. Biol Reprod (2006) 1.22
Role of exosomes in sperm maturation during the transit along the male reproductive tract. Blood Cells Mol Dis (2005) 1.22
Mitochondrial glutathione peroxidase 4 disruption causes male infertility. FASEB J (2009) 1.19
Epididymosomes, prostasomes, and liposomes: their roles in mammalian male reproductive physiology. Reproduction (2013) 1.16
Seleno-independent glutathione peroxidases. More than simple antioxidant scavengers. FEBS J (2007) 1.12
Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice. J Clin Invest (2009) 1.11
Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach. Hum Reprod (2008) 1.11
Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation. Cancer Res (2010) 1.11
FOXL2 activates P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development. J Mol Endocrinol (2006) 1.09
System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency. J Biol Chem (2010) 1.06
Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsy. Antioxid Redox Signal (2014) 1.05
Combined deficiency in glutathione peroxidase 4 and vitamin E causes multiorgan thrombus formation and early death in mice. Circ Res (2013) 1.01
Quantitative and spatial differences in the expression of tryptophan-metabolizing enzymes in mouse epididymis. Cell Tissue Res (2006) 0.99
Rapid proteomic remodeling of cardiac tissue caused by total body ionizing radiation. Proteomics (2011) 0.98
Differential aggregation and functional impairment induced by polyalanine expansions in FOXL2, a transcription factor involved in cranio-facial and ovarian development. Hum Mol Genet (2007) 0.97
The role of thioredoxin reductases in brain development. PLoS One (2008) 0.95
Mitochondrial thioredoxin reductase is essential for early postischemic myocardial protection. Circulation (2011) 0.95
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy. Eur Heart J (2011) 0.92
Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity. FASEB J (2010) 0.92
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling. Proc Natl Acad Sci U S A (2013) 0.91
Cysteine mutant of mammalian GPx4 rescues cell death induced by disruption of the wild-type selenoenzyme. FASEB J (2011) 0.90
Testis-specific expression of the nuclear form of phospholipid hydroperoxide glutathione peroxidase (PHGPx). Biol Chem (2003) 0.90
Epididymis cholesterol homeostasis and sperm fertilizing ability. Asian J Androl (2010) 0.90
Embryonic expression profile of phospholipid hydroperoxide glutathione peroxidase. Gene Expr Patterns (2006) 0.89
Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state. J Biol Chem (2010) 0.89
Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity. Chem Res Toxicol (2013) 0.88
Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2. J Invest Dermatol (2013) 0.87
The nuclear form of glutathione peroxidase 4 is associated with sperm nuclear matrix and is required for proper paternal chromatin decondensation at fertilization. J Cell Physiol (2012) 0.86
LXR and ABCA1 control cholesterol homeostasis in the proximal mouse epididymis in a cell-specific manner. J Lipid Res (2009) 0.86
DNA oxidative damage in mammalian spermatozoa: where and why is the male nucleus affected? Free Radic Biol Med (2013) 0.86
Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activity. Neoplasia (2010) 0.85
Immunolocalization of a plant glutathione peroxidase-like protein. Planta (2004) 0.85
Goat SRY induces testis development in XX transgenic mice. FEBS Lett (2006) 0.85
Posttesticular sperm maturation, infertility, and hypercholesterolemia. Asian J Androl (2015) 0.84
Macrophage migration inhibitory factor in the human epididymis and semen. Mol Hum Reprod (2005) 0.84
Liver X receptors, lipids and their reproductive secrets in the male. Biochim Biophys Acta (2011) 0.84
Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin. Exp Cell Res (2010) 0.84
Liver X receptors and epididymal epithelium physiology. Asian J Androl (2007) 0.83
GPX5, the selenium-independent glutathione peroxidase-encoding single copy gene is differentially expressed in mouse epididymis. Reprod Fertil Dev (2008) 0.83
Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons. Biol Trace Elem Res (2014) 0.83
A study of goat SRY protein expression suggests putative new roles for this gene in the developing testis of a species with long-lasting SRY expression. Dev Dyn (2010) 0.82
Modification of photosynthetic regulation in tomato overexpressing glutathione peroxidase. Biochim Biophys Acta (2005) 0.82
GPX5 is present in the mouse caput and cauda epididymidis lumen at three different locations. Mol Reprod Dev (2002) 0.82
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis. Antioxid Redox Signal (2015) 0.82
Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment. PLoS One (2013) 0.81
Transgenic tomatoes showing higher glutathione peroxydase antioxidant activity are more resistant to an abiotic stress but more susceptible to biotic stresses. Plant Sci (2010) 0.81
Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7. Biochim Biophys Acta (2013) 0.80
Label-free protein profiling of formalin-fixed paraffin-embedded (FFPE) heart tissue reveals immediate mitochondrial impairment after ionising radiation. J Proteomics (2012) 0.80
Thiol switches in mitochondria: operation and physiological relevance. Biol Chem (2015) 0.80
Epididymis response partly compensates for spermatozoa oxidative defects in snGPx4 and GPx5 double mutant mice. PLoS One (2012) 0.79
Electrophoretic characterization of the human sperm-specific enolase at different stages of maturation. J Androl (2004) 0.78
Dietary magnesium depletion does not promote oxidative stress but targets apical cells within the mouse caput epididymidis. Biochim Biophys Acta (2004) 0.77
Effect of vasectomy on gene expression in the epididymis of cynomolgus monkey. Biol Reprod (2003) 0.77
GPX5 orthologs of the mouse epididymis-restricted and sperm-bound selenium-independent glutathione peroxidase are not expressed with the same quantitative and spatial characteristics in large domestic animals. Theriogenology (2005) 0.77
Gene and protein expression in the epididymis of infertile c-ros receptor tyrosine kinase-deficient mice. Biol Reprod (2003) 0.76
B- and T-cell-specific inactivation of thioredoxin reductase 2 does not impair lymphocyte development and maintenance. Biol Chem (2007) 0.76
LXR regulate cholesterol homeostasis in the proximal mouse epididymis. Folia Histochem Cytobiol (2009) 0.75
[Post-testicular protection of male gametes from oxidative damage. The role of the epididymis]. Med Sci (Paris) (2012) 0.75