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1
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Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype.
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Proc Natl Acad Sci U S A
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2002
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3.46
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2
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Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes.
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Nucleic Acids Res
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2003
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2.37
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3
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Learning multiple evolutionary pathways from cross-sectional data.
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J Comput Biol
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2005
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1.74
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4
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Mtreemix: a software package for learning and using mixture models of mutagenetic trees.
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Bioinformatics
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2005
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1.41
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5
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Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.
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Antivir Ther
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2006
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1.37
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6
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Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides.
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Nat Commun
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2011
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1.30
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7
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Predicting Bevirimat resistance of HIV-1 from genotype.
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BMC Bioinformatics
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2010
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1.30
|
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8
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Prediction of co-receptor usage of HIV-1 from genotype.
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PLoS Comput Biol
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2010
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1.29
|
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9
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Computational methods for the design of effective therapies against drug resistant HIV strains.
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Bioinformatics
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2005
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1.27
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10
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Structures of the Common Cyclodextrins and Their Larger Analogues-Beyond the Doughnut.
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Chem Rev
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1998
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1.20
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11
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Estimating HIV evolutionary pathways and the genetic barrier to drug resistance.
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J Infect Dis
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2005
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1.19
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12
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Characterization of methicillin-resistant Staphylococcus spp. carrying the mecC gene, isolated from wildlife.
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J Antimicrob Chemother
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2013
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1.17
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13
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Tenofovir resistance and resensitization.
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Antimicrob Agents Chemother
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2003
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1.10
|
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14
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Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failure.
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J Clin Virol
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2009
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1.06
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15
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Methods for optimizing antiviral combination therapies.
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Bioinformatics
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2003
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1.02
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16
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Sonic hedgehog shedding results in functional activation of the solubilized protein.
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Dev Cell
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2011
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1.02
|
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17
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CD8+ T-cell response promotes evolution of hepatitis C virus nonstructural proteins.
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Gastroenterology
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2011
|
1.01
|
|
18
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Screening for disulfide bonds in proteins by MALDI in-source decay and LIFT-TOF/TOF-MS.
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Anal Chem
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2002
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1.00
|
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19
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The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir.
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Antiviral Res
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2012
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1.00
|
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20
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Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate.
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Proc Natl Acad Sci U S A
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2010
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0.99
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21
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SearchXLinks. A program for the identification of disulfide bonds in proteins from mass spectra.
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Anal Chem
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2006
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0.94
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22
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Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patients.
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J Infect
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2008
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0.94
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23
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Novel algorithm for non-invasive assessment of fibrosis in NAFLD.
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PLoS One
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2013
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0.93
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|
24
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Structure of HIV-1 quasi-species as early indicator for switches of co-receptor tropism.
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AIDS Res Ther
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2010
|
0.93
|
|
25
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Interpol: An R package for preprocessing of protein sequences.
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BioData Min
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2011
|
0.92
|
|
26
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Machine learning on normalized protein sequences.
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BMC Res Notes
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2011
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0.92
|
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27
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Microfluidic biochip for chemiluminescent detection of allergen-specific antibodies.
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Biosens Bioelectron
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2008
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0.91
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28
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Alternative proteolytic processing of hepatocyte growth factor during wound repair.
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Am J Pathol
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2009
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0.91
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29
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The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated protein.
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Hum Mol Genet
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2012
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0.89
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30
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Improved Bevirimat resistance prediction by combination of structural and sequence-based classifiers.
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BioData Min
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2011
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0.88
|
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31
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Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy.
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J Clin Virol
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2005
|
0.88
|
|
32
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Photoaffinity labelling of the human GM2-activator protein. Mechanistic insight into ganglioside GM2 degradation.
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Eur J Biochem
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2004
|
0.87
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33
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Structural modeling of ataxin-3 reveals distant homology to adaptins.
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Proteins
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2003
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0.86
|
|
34
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Evolutionary Pareto-optimization of stably folding peptides.
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BMC Bioinformatics
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2008
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0.86
|
|
35
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Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.
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J Virol
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2011
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0.86
|
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36
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Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'.
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Virol Sin
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2014
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0.85
|
|
37
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An emerging role of Sonic hedgehog shedding as a modulator of heparan sulfate interactions.
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J Biol Chem
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2012
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0.84
|
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38
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A multiobjective evolutionary method for the design of peptidic mimotopes.
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J Comput Biol
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2006
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0.84
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|
39
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A small set of succinct signature patterns distinguishes Chinese and non-Chinese HIV-1 genomes.
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PLoS One
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2013
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0.83
|
|
40
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The B-cell epitope of the monoclonal anti-factor VIII antibody ESH8 characterized by peptide array analysis.
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Thromb Haemost
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2008
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0.83
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41
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The normal-mode entropy in the MM/GBSA method: effect of system truncation, buffer region, and dielectric constant.
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J Chem Inf Model
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2012
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0.82
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42
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The enzyme-binding region of human GM2-activator protein.
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FEBS J
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2006
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0.82
|
|
43
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mecC- and mecA-positive meticillin-resistant Staphylococcus aureus (MRSA) isolated from livestock sharing habitat with wildlife previously tested positive for mecC-positive MRSA.
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Vet Dermatol
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2014
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0.81
|
|
44
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Parental origin and functional relevance of a de novo UBE3A variant.
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Eur J Med Genet
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2010
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0.80
|
|
45
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Design of a modular protein-based MRI contrast agent for targeted application.
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PLoS One
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2013
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0.80
|
|
46
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Transient domain interactions enhance the affinity of the mitotic regulator Pin1 toward phosphorylated peptide ligands.
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Structure
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2013
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0.80
|
|
47
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An additional glucose dehydrogenase from Sulfolobus solfataricus: fine-tuning of sugar degradation?
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Biochem Soc Trans
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2011
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0.79
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48
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Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60.
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Chromosoma
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2009
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0.78
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49
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Single-domain parvulins constitute a specific marker for recently proposed deep-branching archaeal subgroups.
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Evol Bioinform Online
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2011
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0.78
|
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50
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Estimating affinities of calcium ions to proteins.
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Adv Appl Bioinform Chem
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2010
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0.77
|
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51
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Partial reduction and two-step modification of proteins for identification of disulfide bonds.
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Anal Chem
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2002
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0.76
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52
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Inference of global HIV-1 sequence patterns and preliminary feature analysis.
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Virol Sin
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2013
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0.76
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53
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A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of arms.
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Org Biomol Chem
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2013
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0.76
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54
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Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection.
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Cell Physiol Biochem
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2015
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0.75
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55
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The antiretroviral potency of emtricitabine is approximately 3-fold higher compared to lamivudine in dual human immunodeficiency virus type 1 infection/competition experiments in vitro.
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Antiviral Res
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2010
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0.75
|