Once-daily opioids for chronic dyspnea: a dose increment and pharmacovigilance study.

PubWeight™: 1.42‹?› | Rank: Top 5%

🔗 View Article (PMID 21458217)

Published in J Pain Symptom Manage on March 31, 2011

Authors

David C Currow1, Christine McDonald, Sheila Oaten, Bernadette Kenny, Peter Allcroft, Peter Frith, Michael Briffa, Miriam J Johnson, Amy P Abernethy

Author Affiliations

1: Discipline, Palliative and Supportive Services, Flinders University, Bedford Park, SA, Australia. david.currow@flinders.edu.au

Associated clinical trials:

Morphine or Fentanyl for Refractory Dyspnea in COPD (MoreFoRCOPD) | NCT03834363

Articles citing this

Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective study. BMJ (2014) 3.75

Shortness of breath and cough in patients in palliative care. Dtsch Arztebl Int (2013) 1.55

Dyspnea review for the palliative care professional: treatment goals and therapeutic options. J Palliat Med (2012) 1.54

Guidelines for the diagnosis and treatment of malignant pleural mesothelioma. J Thorac Dis (2013) 1.27

Managing dyspnea in patients with advanced chronic obstructive pulmonary disease: a Canadian Thoracic Society clinical practice guideline. Can Respir J (2011) 1.20

Incident opioid drug use among older adults with chronic obstructive pulmonary disease: a population-based cohort study. Br J Clin Pharmacol (2015) 1.07

Using opioids to treat dyspnea in advanced COPD: attitudes and experiences of family physicians and respiratory therapists. Can Fam Physician (2012) 0.99

Caring for the older person with chronic obstructive pulmonary disease. JAMA (2012) 0.96

The longitudinal pattern of response when morphine is used to treat chronic refractory dyspnea. J Palliat Med (2013) 0.92

Perspectives of patients, family caregivers and physicians about the use of opioids for refractory dyspnea in advanced chronic obstructive pulmonary disease. CMAJ (2012) 0.90

Supportive and palliative care for lung cancer patients. J Thorac Dis (2013) 0.89

Opioid therapy for refractory dyspnea in patients with advanced chronic obstructive pulmonary disease: patients' experiences and outcomes. CMAJ Open (2013) 0.85

Exercise therapy in the management of dyspnea in patients with cancer. Curr Opin Support Palliat Care (2012) 0.84

Prospectively collected characteristics of adult patients, their consultations and outcomes as they report breathlessness when presenting to general practice in Australia. PLoS One (2013) 0.82

Prescription of opioids for breathlessness in end-stage COPD: a national population-based study. Int J Chron Obstruct Pulmon Dis (2016) 0.81

Evidence-based intervention for chronic refractory breathlessness: practical therapies that make a difference. Br J Gen Pract (2013) 0.79

Patient considerations and drug selection in the treatment of idiopathic pulmonary fibrosis. Ther Clin Risk Manag (2016) 0.77

[Pharmacological therapy of refractory dyspnoea : a systematic literature review]. Schmerz (2012) 0.77

Developing a Research Agenda for Integrating Palliative Care into Critical Care and Pulmonary Practice To Improve Patient and Family Outcomes. J Palliat Med (2017) 0.75

Hospital without dyspnea: rationale and design of a multidisciplinary intervention. J Geriatr Cardiol (2016) 0.75

Academic detailing of general practitioners by a respiratory physician for diagnosis and management of refractory breathlessness: a randomised pilot study. BMC Health Serv Res (2015) 0.75

Symptom management in the older adult: 2015 update. Clin Geriatr Med (2015) 0.75

End-of-life care of patients with idiopathic pulmonary fibrosis. BMC Palliat Care (2016) 0.75

Opioids: an unexplored option for treatment of dyspnea in IPF. Eur Clin Respir J (2016) 0.75

Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors? BMJ Open (2015) 0.75

Study protocol: a phase III randomised, double-blind, parallel arm, stratified, block randomised, placebo-controlled trial investigating the clinical effect and cost-effectiveness of sertraline for the palliative relief of breathlessness in people with chronic breathlessness. BMJ Open (2016) 0.75

Aerosol furosemide for dyspnea: Controlled delivery does not improve effectiveness. Respir Physiol Neurobiol (2017) 0.75

Articles by these authors

(truncated to the top 100)

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

American Society of Clinical Oncology provisional clinical opinion: the integration of palliative care into standard oncology care. J Clin Oncol (2012) 7.54

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem (2005) 6.18

The financial toxicity of cancer treatment: a pilot study assessing out-of-pocket expenses and the insured cancer patient's experience. Oncologist (2013) 4.33

Generalist plus specialist palliative care--creating a more sustainable model. N Engl J Med (2013) 4.27

Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective study. BMJ (2014) 3.75

RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. J Immunol (2007) 3.43

Oncologist communication about emotion during visits with patients with advanced cancer. J Clin Oncol (2007) 3.07

Psychological interventions for arthritis pain management in adults: a meta-analysis. Health Psychol (2007) 2.92

Characteristics of oncology clinical trials: insights from a systematic analysis of ClinicalTrials.gov. JAMA Intern Med (2013) 2.86

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology (2010) 2.83

Recommendations for incorporating patient-reported outcomes into clinical comparative effectiveness research in adult oncology. J Clin Oncol (2012) 2.82

Stage migration, selection bias, and survival associated with the adoption of positron emission tomography among medicare beneficiaries with non-small-cell lung cancer, 1998-2003. J Clin Oncol (2012) 2.72

Changes in the use and costs of diagnostic imaging among Medicare beneficiaries with cancer, 1999-2006. JAMA (2010) 2.68

Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2. J Immunol (2008) 2.65

Subcutaneous furosemide in advanced heart failure: has clinical practice run ahead of the evidence base? BMJ Support Palliat Care (2011) 2.60

Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ (2003) 2.40

Trends in hospital admissions and mortality from asthma and chronic obstructive pulmonary disease in Australia, 1993-2003. Med J Aust (2007) 2.20

The language of breathlessness differentiates between patients with COPD and age-matched adults. Chest (2008) 2.19

Recommendations for clinical trials of off-label drugs used to treat advanced-stage cancer. J Clin Oncol (2012) 2.15

Rapid, responsive, relevant (R3) research: a call for a rapid learning health research enterprise. Clin Transl Med (2013) 2.10

Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha. EMBO J (2002) 2.01

Promoting patient centred palliative care through case conferencing. Aust Fam Physician (2007) 1.98

Full disclosure--out-of-pocket costs as side effects. N Engl J Med (2013) 1.90

Psychological approaches to understanding and treating disease-related pain. Annu Rev Psychol (2005) 1.87

Development of a subject search filter to find information relevant to palliative care in the general medical literature. J Med Libr Assoc (2006) 1.82

Enhancing communication between oncologists and patients with a computer-based training program: a randomized trial. Ann Intern Med (2011) 1.78

Use of tablet personal computers for sensitive patient-reported information. J Support Oncol (2009) 1.73

Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense. J Immunol (2006) 1.73

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis. Cell Metab (2006) 1.70

Prescribing in palliative care as death approaches. J Am Geriatr Soc (2007) 1.68

A national snapshot of satisfaction with breast cancer procedures. Ann Surg Oncol (2014) 1.62

Defining best supportive care. J Clin Oncol (2008) 1.60

Managing comorbidities in patients at the end of life. BMJ (2004) 1.59

Handheld computers for data entry: high tech has its problems too. Trials (2007) 1.57

Fatigue is the most important symptom for advanced cancer patients who have had chemotherapy. J Natl Compr Canc Netw (2008) 1.55

Dyspnea review for the palliative care professional: treatment goals and therapeutic options. J Palliat Med (2012) 1.54

Analyzing phase III studies in hospice/palliative care. a solution that sits between intention-to-treat and per protocol analyses: the palliative-modified ITT analysis. J Pain Symptom Manage (2012) 1.53

The NOD2-RICK complex signals from the plasma membrane. J Biol Chem (2007) 1.50

Supporting clinical practice decisions with real-time patient-reported outcomes. J Clin Oncol (2011) 1.41

Importance of health information technology, electronic health records, and continuously aggregating data to comparative effectiveness research and learning health care. J Clin Oncol (2012) 1.41

Primary thromboprophylaxis for hospice inpatients: who needs it? Palliat Med (2011) 1.40

Do the trajectories of dyspnea differ in prevalence and intensity by diagnosis at the end of life? A consecutive cohort study. J Pain Symptom Manage (2010) 1.37

Studying communication in oncologist-patient encounters: the SCOPE Trial. Palliat Med (2006) 1.37

Financial toxicity, Part I: a new name for a growing problem. Oncology (Williston Park) (2013) 1.33

Variations in use of PET among Medicare beneficiaries with non-small cell lung cancer, 1998-2007. Radiology (2013) 1.30

Association between the Medicare Modernization Act of 2003 and patient wait times and travel distance for chemotherapy. JAMA (2008) 1.28

Patient-oncologist communication in advanced cancer: predictors of patient perception of prognosis. Support Care Cancer (2008) 1.27

Prognostic significance of functional capacity and exercise behavior in patients with metastatic non-small cell lung cancer. Lung Cancer (2011) 1.26

Consensus-based standards for best supportive care in clinical trials in advanced cancer. Lancet Oncol (2012) 1.23

Decision making and quality of life in the treatment of cancer: a review. Support Care Cancer (2008) 1.19

Patient experiences with communication about sex during and after treatment for cancer. Psychooncology (2011) 1.17

A framework for generalizability in palliative care. J Pain Symptom Manage (2008) 1.17

Longitudinal patient-reported performance status assessment in the cancer clinic is feasible and prognostic. J Oncol Pract (2011) 1.17

Minimization of heatwave morbidity and mortality. Am J Prev Med (2013) 1.16

Hospices' preparation and practices for quality measurement. J Pain Symptom Manage (2010) 1.14

Developing the evidence base for palliative care: formation of the palliative care research cooperative and its first trial. Hosp Pract (1995) (2010) 1.14

"Not the 'grim reaper service'": an assessment of provider knowledge, attitudes, and perceptions regarding palliative care referral barriers in heart failure. J Am Heart Assoc (2014) 1.14

A community population survey of prevalence and severity of dyspnea in adults. J Pain Symptom Manage (2009) 1.14

The Medicare Modernization Act and reimbursement for outpatient chemotherapy: do patients perceive changes in access to care? Cancer (2007) 1.13

Self-reported financial burden and satisfaction with care among patients with cancer. Oncologist (2014) 1.13

Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis. Am J Physiol Endocrinol Metab (2012) 1.12

CareSearch: finding and evaluating Australia's missing palliative care literature. BMC Palliat Care (2005) 1.12

Specialist palliative care needs of whole populations: a feasibility study using a novel approach. Palliat Med (2004) 1.11

A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses. J Biol Chem (2010) 1.11

Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB-mediated mechanism. Proc Natl Acad Sci U S A (2013) 1.11

Crystal structure of the Nod1 caspase activation and recruitment domain. Biochem Biophys Res Commun (2006) 1.10

Longitudinal patterns of chemotherapy use in metastatic colorectal cancer. J Oncol Pract (2009) 1.10

Hospital can be the actively chosen place for death. J Clin Oncol (2013) 1.09

Uncovering an invisible network of direct caregivers at the end of life: a population study. Palliat Med (2013) 1.09

Continuous monitoring of circadian glycemic patterns in patients receiving prednisolone for COPD. J Clin Endocrinol Metab (2011) 1.08

Unmet spiritual care needs impact emotional and spiritual well-being in advanced cancer patients. Support Care Cancer (2011) 1.08

Indwelling catheters for the management of refractory malignant ascites: a systematic literature overview and retrospective chart review. J Pain Symptom Manage (2009) 1.08

Management of venous thromboembolism in patients with advanced cancer: a systematic review and meta-analysis. Lancet Oncol (2008) 1.07

Stakeholder perspectives on implementing the National Cancer Institute's patient-reported outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE). Transl Behav Med (2011) 1.07

Timing of end-of-life care discussion with performance on end-of-life quality indicators in ovarian cancer. Gynecol Oncol (2013) 1.07

Populations who die without specialist palliative care: does lower uptake equate with unmet need? Palliat Med (2008) 1.06

Electronic toxicity monitoring and patient-reported outcomes. Cancer J (2011) 1.06

Establishing a regional, multisite database for quality improvement and service planning in community-based palliative care and hospice. J Palliat Med (2010) 1.06

Post-traumatic stress symptoms in long-term non-Hodgkin's lymphoma survivors: does time heal? J Clin Oncol (2011) 1.03

An international initiative to create a collaborative for pharmacovigilance in hospice and palliative care clinical practice. J Palliat Med (2012) 1.02

Quality of life among long-term survivors of non-Hodgkin lymphoma: a follow-up study. J Clin Oncol (2012) 1.01

A framework for understanding cancer comparative effectiveness research data needs. J Clin Epidemiol (2012) 1.00

Discontinuation of statins in routine care settings. Ann Intern Med (2013) 1.00

A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways. Sci Signal (2013) 0.99

Overcoming recruitment challenges in palliative care clinical trials. J Oncol Pract (2013) 0.99

Human milk hyaluronan enhances innate defense of the intestinal epithelium. J Biol Chem (2013) 0.98

Comfort in the last 2 weeks of life: relationship to accessing palliative care services. Support Care Cancer (2008) 0.97

Need for global partnership in cancer care: perceptions of cancer care researchers attending the 2010 australia and Asia pacific clinical oncology research development workshop. J Oncol Pract (2011) 0.96

Improving the methodologic and ethical validity of best supportive care studies in oncology: lessons from a systematic review. J Clin Oncol (2009) 0.96

Coping with sexual concerns after cancer: the use of flexible coping. Support Care Cancer (2010) 0.96

Opioids for chronic refractory breathlessness: patient predictors of beneficial response. Eur Respir J (2012) 0.96

Palliative care clinical research networks, a requirement for evidence-based palliative care: time for coordinated action. J Palliat Med (2007) 0.96

Quality palliative care: practitioners' needs for dynamic lifelong learning. J Pain Symptom Manage (2005) 0.95

Correlates of quality of life-related outcomes in breast cancer patients participating in the Pathfinders pilot study. Psychooncology (2011) 0.95

Collecting data on quality is feasible in community-based palliative care. J Pain Symptom Manage (2011) 0.95

Clinically important differences in the intensity of chronic refractory breathlessness. J Pain Symptom Manage (2013) 0.94

Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms. Breast Cancer Res Treat (2011) 0.94

A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy. J Biol Chem (2012) 0.94

Palliative care needs of patients with cancer living in the community. J Oncol Pract (2011) 0.94