Published in Eur J Med Res on February 24, 2011
Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice. Cancer Prev Res (Phila) (2013) 0.98
Apo-10'-lycopenoic acid, a lycopene metabolite, increases sirtuin 1 mRNA and protein levels and decreases hepatic fat accumulation in ob/ob mice. J Nutr (2012) 0.97
Vitamin E and nonalcoholic fatty liver disease. Curr Opin Clin Nutr Metab Care (2012) 0.96
Dietary habits and behaviors associated with nonalcoholic fatty liver disease. World J Gastroenterol (2014) 0.91
Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention. Nutrients (2013) 0.89
Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep (2015) 0.88
Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis. Nutrients (2016) 0.84
Antioxidant therapy in nonalcoholic steatohepatitis. Hepat Res Treat (2012) 0.83
Oxidative stress: New insights on the association of non-alcoholic fatty liver disease and atherosclerosis. World J Hepatol (2015) 0.83
Role of vitamins in gastrointestinal diseases. World J Gastroenterol (2015) 0.82
Carotenoids and non-alcoholic fatty liver disease. Hepatobiliary Surg Nutr (2015) 0.82
Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice. Cancer Prev Res (Phila) (2014) 0.82
Effects of rosuvastatin and/or β-carotene on non-alcoholic fatty liver in rats. Res Pharm Sci (2015) 0.81
Non-alcoholic steatohepatitis: the therapeutic challenge of a global epidemic. Ann Gastroenterol (2012) 0.81
Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice. J Nutr (2014) 0.80
Greater serum carotenoid levels associated with lower prevalence of nonalcoholic fatty liver disease in Chinese adults. Sci Rep (2015) 0.79
Association between vitamin E and non-alcoholic steatohepatitis: a meta-analysis. Int J Clin Exp Med (2015) 0.76
Hepatocellular carcinoma in non-alcoholic steatohepatitis: Current knowledge and implications for management. World J Hepatol (2017) 0.75
Major components of metabolic syndrome and nutritional intakes in different genotype of UCP2 -866G/A gene polymorphisms in patients with NAFLD. J Transl Med (2016) 0.75
Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments. Nutrients (2017) 0.75
Antioxidant vitamins in the context of nonalcoholic fatty liver disease in obese children and adolescents. Rev Paul Pediatr (2013) 0.75
Major Components of Metabolic Parameters and Nutritional Intakes in Different Genotypes of Adiponectin +276 G>T Gene Polymorphism in Non-Diabetes and Non-Alcoholic Iranian Fatty Liver Patients. Avicenna J Med Biotechnol (2017) 0.75
Mesozeaxanthin protects the liver and reduces cardio-metabolic risk factors in an insulin resistant rodent model. Food Nutr Res (2017) 0.75
Nonalcoholic fatty liver disease. N Engl J Med (2002) 22.41
Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol (1999) 14.07
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med (2010) 13.33
Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis. Am J Gastroenterol (2003) 4.05
Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E. Hepatology (2003) 3.51
Carotenoids and human health. Pharmacol Res (2007) 3.07
Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study. J Pediatr (2000) 2.88
Vitamins E and C, beta-carotene, and other carotenoids as antioxidants. Am J Clin Nutr (1995) 1.97
Plasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot study. Aliment Pharmacol Ther (2001) 1.73
Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol (2006) 1.67
Low vitamin E content in plasma of patients with alcoholic liver disease, hemochromatosis and Wilson's disease. J Hepatol (1994) 1.52
Analysis of lipophilic antioxidants in human serum and tissues: tocopherols and carotenoids. J Chromatogr A (2001) 0.90
The impact of patient-centered care on outcomes. J Fam Pract (2000) 15.07
Hydroperoxide metabolism in mammalian organs. Physiol Rev (1979) 14.13
Randomization by cluster. Sample size requirements and analysis. Am J Epidemiol (1981) 9.21
WHO antenatal care randomised trial for the evaluation of a new model of routine antenatal care. Lancet (2001) 6.86
Sample size and optimal designs for reliability studies. Stat Med (1998) 6.80
Small sample performance of tests of homogeneity of odds ratios in K 2 x 2 tables. Stat Med (1992) 6.20
Evaluation of a palliative care service: problems and pitfalls. BMJ (1994) 5.70
Functional significance of cell volume regulatory mechanisms. Physiol Rev (1998) 4.59
Developments in cluster randomized trials and Statistics in Medicine. Stat Med (2007) 4.12
Long-term survival in patients with hereditary hemochromatosis. Gastroenterology (1996) 4.00
Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N Engl J Med (1996) 3.41
Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys (1989) 3.33
Approaches to sample size estimation in the design of clinical trials--a review. Stat Med (1984) 3.28
Sample size requirements for reliability studies. Stat Med (1987) 3.15
Analysis of data arising from a stratified design with the cluster as unit of randomization. Stat Med (1987) 3.01
Prognosis of chronic hepatitis C: results of a large, prospective cohort study. Hepatology (1998) 3.00
A communitywide outbreak of giardiasis with evidence of transmission by a municipal water supply. Ann Intern Med (1977) 2.87
Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Methods Enzymol (1981) 2.85
Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha. Biochem J (1989) 2.85
Non-alcoholic duct destructive chronic pancreatitis. Gut (1997) 2.79
Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation. Experientia (1981) 2.71
Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. Proc Natl Acad Sci U S A (1987) 2.51
Methods in health service research. Evaluation of health interventions at area and organisation level. BMJ (1999) 2.48
Chemistry of biologically important synthetic organoselenium compounds. Chem Rev (2001) 2.41
The merits of matching in community intervention trials: a cautionary tale. Stat Med (1997) 2.14
Prior cytomegalovirus infection and the risk of restenosis after percutaneous transluminal coronary balloon angioplasty. Circulation (1999) 2.13
The estimation of intraclass correlation in the analysis of family data. Biometrics (1980) 2.06
Randomised trialomania? The multicentre liver transplant trials of tacrolimus. Lancet (1995) 2.04
[Demonstration of HFE polymorphism in German patients with hereditary hemochromatosis]. Dtsch Med Wochenschr (1999) 2.03
Adjustments to the Mantel-Haenszel chi-square statistic and odds ratio variance estimator when the data are clustered. Stat Med (1987) 2.00
Responsiveness of the short form-36, disability of the arm, shoulder, and hand questionnaire, patient-rated wrist evaluation, and physical impairment measurements in evaluating recovery after a distal radius fracture. J Hand Surg Am (2000) 1.98
Vitamins E and C, beta-carotene, and other carotenoids as antioxidants. Am J Clin Nutr (1995) 1.97
A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). Biochem Pharmacol (1984) 1.90
Reversible conversion of nitroxyl anion to nitric oxide by superoxide dismutase. Proc Natl Acad Sci U S A (1991) 1.87
Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone. Gastroenterology (1999) 1.87
The use of perfusion of liver and other organs for the study of microsomal electron-transport and cytochrome P-450 systems. Methods Enzymol (1978) 1.86
Do family physicians need medical assistants to detect and manage hypertension? CMAJ (1986) 1.85
The role of H 2 O 2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors. Arch Biochem Biophys (1973) 1.81
Current and future challenges in the design and analysis of cluster randomization trials. Stat Med (2001) 1.80
Hepatotoxicity of erythromycin estolate during pregnancy. Antimicrob Agents Chemother (1977) 1.75
The Pittsburgh randomized trial of tacrolimus compared to cyclosporine for hepatic transplantation. J Am Coll Surg (1996) 1.71
Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis. Gastroenterology (1997) 1.70
Antioxidant functions of vitamins. Vitamins E and C, beta-carotene, and other carotenoids. Ann N Y Acad Sci (1992) 1.70
Construction of confidence limits about effect measures: a general approach. Stat Med (2008) 1.69
Evidence for a vasoconstriction-mediating receptor for UTP, distinct from the P2 purinoceptor, in rabbit ear artery. Naunyn Schmiedebergs Arch Pharmacol (1987) 1.68
Insulin resistance, the metabolic syndrome, and nonalcoholic fatty liver disease. J Clin Endocrinol Metab (2004) 1.68
Expression of the peripheral-type benzodiazepine receptor and apoptosis induction in hepatic stellate cells. Gastroenterology (2001) 1.66
Hepatorenal reflex regulating kidney function. Hepatology (1991) 1.61
Plasma lipids and lipoproteins in vegetarians and controls. N Engl J Med (1975) 1.59
Oxidative stress: damage to intact cells and organs. Philos Trans R Soc Lond B Biol Sci (1985) 1.55
Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols. Am J Clin Nutr (1991) 1.54
Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen. Biochemistry (1991) 1.53
Low vitamin E content in plasma of patients with alcoholic liver disease, hemochromatosis and Wilson's disease. J Hepatol (1994) 1.52
Plasmodium knowlesi infection imported to Germany, January 2013. Euro Surveill (2013) 1.50
Cortical origin of mini-asterixis in hepatic encephalopathy. Neurology (2002) 1.50
Exocytosis in secretory cells of rat lacrimal gland. Peroxidase release from lobules and isolated cells upon cholinergic stimulation. J Cell Biol (1976) 1.50
Persistence of middle-ear effusion after acute otitis media in children. N Engl J Med (1979) 1.50
Functional food science and defence against reactive oxidative species. Br J Nutr (1998) 1.50
Clinical spectrum of gonococcal infection in women. Lancet (1977) 1.49
Reduced and oxidized glutathione efflux from liver. FEBS Lett (1978) 1.49
LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett (1999) 1.46
Anal endosonography and manometry: comparison in patients with defecation problems. Dis Colon Rectum (1997) 1.46
Patient versus injury factors as predictors of pain and disability six months after a distal radius fracture. J Clin Epidemiol (2002) 1.46
Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver. Eur J Biochem (1983) 1.43
Cardiotoxicity of the antiproliferative compound fluorouracil. Drugs (1999) 1.42
Vitamin E in humans: demand and delivery. Annu Rev Nutr (1996) 1.42
Randomised study of n of 1 trials versus standard practice. BMJ (1996) 1.41
Actions of extracellular UTP and ATP in perfused rat liver. A comparative study. Eur J Biochem (1987) 1.40
Are ordinal models useful for classification? Stat Med (1991) 1.40
Work of breathing, inspiratory flow response, and expiratory resistance during continuous positive airway pressure with the ventilators EVITA-2, EVITA-4 and SV 300. Intensive Care Med (1998) 1.39
Lycopene: a biologically important carotenoid for humans? Arch Biochem Biophys (1996) 1.38
Low-level chemiluminescence as an indicator of singlet molecular oxygen in biological systems. Methods Enzymol (1984) 1.37
Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. J Nutr (1992) 1.35
Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart. J Biol Chem (1986) 1.33
Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr (1997) 1.31
Water, K+, H+, lactate and glucose fluxes during cell volume regulation in perfused rat liver. Pflugers Arch (1989) 1.31
Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide. Biochem Pharmacol (1983) 1.31
Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion. J Biol Chem (1999) 1.31
Increased biliary glutathione disulfide release in chronically ethanol-treated rats. FEBS Lett (1979) 1.30
Hydroperoxide-metabolizing systems in rat liver. Eur J Biochem (1975) 1.29
Characterization and natural course of cardiac autonomic nervous dysfunction in HIV-infected patients. AIDS (1997) 1.29
A regression approach to the analysis of data arising from cluster randomization. Int J Epidemiol (1985) 1.28
Response to interferon alfa is hepatitis B virus genotype dependent: genotype A is more sensitive to interferon than genotype D. Gut (2005) 1.28
The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver. J Biol Chem (1982) 1.27
An empirical study of cluster randomization. Int J Epidemiol (1982) 1.26
Meta-analyses in systematic reviews of randomized controlled trials in perinatal medicine: comparison of fixed and random effects models. Stat Med (2001) 1.26
Factors affecting the comparability of meta-analyses and largest trials results in perinatology. J Clin Epidemiol (1997) 1.24
S-nitrosylation and S-glutathiolation of protein sulfhydryls by S-nitroso glutathione. Arch Biochem Biophys (1999) 1.24
Mitochondrial and cytosolic NADPH systems and isocitrate dehydrogenase indicator metabolites during ureogensis from ammonia in isolated rat hepatocytes. Eur J Biochem (1977) 1.24
Singlet molecular oxygen causes loss of biological activity in plasmid and bacteriophage DNA and induces single-strand breaks. Biochim Biophys Acta (1989) 1.24
Application of the McNemar test to non-independent matched pair data. Stat Med (1991) 1.22
Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle. J Hepatol (1985) 1.22
Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B. Hepatology (2000) 1.22
Heme occupancy of catalase in hemoglobin-free perfused rat liver and of isolated rat liver catalase. Arch Biochem Biophys (1973) 1.22
Activation of pyruvate dehydrogenase during metabolism of ammonium ions in hemoglobin-free perfused rat liver. Eur J Biochem (1975) 1.21
Optimal intravenous dosing strategies for sedatives and analgesics in the intensive care unit. Crit Care Clin (1995) 1.21