PubRank

Peter N Monk

Author PubWeight™ 42.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74). J Biol Chem 2001 1.80
2 Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol 2008 1.75
3 C5L2 is a functional receptor for acylation-stimulating protein. J Biol Chem 2005 1.69
4 Changes and regulation of the C5a receptor on neutrophils during septic shock in humans. J Immunol 2013 1.57
5 Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation. Blood 2004 1.56
6 The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis. J Immunol 2008 1.52
7 Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis. Glia 2005 1.47
8 The human complement fragment receptor, C5L2, is a recycling decoy receptor. Mol Immunol 2008 1.45
9 The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein. J Biol Chem 2003 1.41
10 Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration. FASEB J 2006 1.33
11 Complement component 5a (C5a). Int J Biochem Cell Biol 2009 1.24
12 C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism. J Biol Chem 2003 1.22
13 International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol Rev 2013 1.22
14 Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis. FASEB J 2012 1.21
15 Changes in the novel orphan, C5a receptor (C5L2), during experimental sepsis and sepsis in humans. J Immunol 2005 1.19
16 Ligand specificity of the anaphylatoxin C5L2 receptor and its regulation on myeloid and epithelial cell lines. J Biol Chem 2006 1.17
17 Recombinant extracellular domains of tetraspanin proteins are potent inhibitors of the infection of macrophages by human immunodeficiency virus type 1. J Virol 2006 1.15
18 Astrocyte function and role in motor neuron disease: a future therapeutic target? Glia 2009 1.09
19 De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation. J Med Chem 2012 1.04
20 Characterisation of receptor binding by the chemotaxis inhibitory protein of Staphylococcus aureus and the effects of the host immune response. Mol Immunol 2007 1.01
21 Complement C3a receptors in the pituitary gland: a novel pathway by which an innate immune molecule releases hormones involved in the control of inflammation. FASEB J 2003 0.98
22 Structural requirements for the inhibitory action of the CD9 large extracellular domain in sperm/oocyte binding and fusion. Biochem Biophys Res Commun 2003 0.97
23 Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site. J Biol Chem 2005 0.95
24 The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding. J Biol Chem 2006 0.95
25 ALS: life and death in a bad neighborhood. Nat Med 2006 0.90
26 Strategies for targeting tetraspanin proteins: potential therapeutic applications in microbial infections. BioDrugs 2009 0.90
27 The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9. Cell Mol Life Sci 2011 0.89
28 C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay. J Immunol 2012 0.89
29 Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells. Immunology 2009 0.87
30 Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1. Neuroreport 2009 0.86
31 A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function. BMC Neurosci 2011 0.85
32 The role of tetraspanins in fusion. Biochem Soc Trans 2011 0.84
33 Complement factors C3a and C5a have distinct hemodynamic effects in the rat. Int Immunopharmacol 2009 0.84
34 Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells. Infect Immun 2011 0.82
35 Interspecies contamination of the KM3 cell line: implications for CD63 function in melanoma metastasis. Int J Cancer 2003 0.79
36 Characterisation of C5a receptor agonists from phage display libraries. Biochem Pharmacol 2003 0.78
37 Complement C5a receptors in the pituitary gland: expression and function. J Endocrinol 2008 0.78
38 Contrasting effects of cerebrospinal fluid from motor neuron disease patients on the survival of primary motor neurons cultured with or without glia. Amyotroph Lateral Scler 2011 0.76
39 Wild-type but not mutant SOD1 transgenic astrocytes promote the efficient generation of motor neuron progenitors from mouse embryonic stem cells. BMC Neurosci 2013 0.75