PubRank

André J Ouellette

Author PubWeight™ 20.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice. Dev Biol 2009 1.68
2 Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization. J Am Chem Soc 2011 1.48
3 Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen. J Biol Chem 2009 1.28
4 Strain-specific polymorphisms in Paneth cell α-defensins of C57BL/6 mice and evidence of vestigial myeloid α-defensin pseudogenes. Infect Immun 2010 1.06
5 Electropositive charge in alpha-defensin bactericidal activity: functional effects of Lys-for-Arg substitutions vary with the peptide primary structure. Infect Immun 2009 1.04
6 CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity. J Immunol 2012 1.00
7 In vitro activation of the rhesus macaque myeloid alpha-defensin precursor proRMAD-4 by neutrophil serine proteinases. J Biol Chem 2008 0.95
8 Anionic amino acids near the pro-alpha-defensin N terminus mediate inhibition of bactericidal activity in mouse pro-cryptdin-4. J Biol Chem 2008 0.95
9 Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities. J Leukoc Biol 2010 0.94
10 Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis. PLoS One 2012 0.89
11 Arginine in α-defensins: differential effects on bactericidal activity correspond to geometry of membrane curvature generation and peptide-lipid phase behavior. J Biol Chem 2012 0.89
12 The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids 2012 0.89
13 Paneth cell-mediated multiorgan dysfunction after acute kidney injury. J Immunol 2012 0.87
14 Elevated expression of Paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action. J Biol Chem 2010 0.85
15 Persistence of gut mucosal innate immune defenses by enteric α-defensin expression in the simian immunodeficiency virus model of AIDS. J Immunol 2010 0.84
16 High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3. PLoS One 2012 0.83
17 Expression and purification of recombinant alpha-defensins and alpha-defensin precursors in Escherichia coli. Methods Mol Biol 2010 0.83
18 Alternative luminal activation mechanisms for paneth cell α-defensins. J Biol Chem 2012 0.82
19 Hydrophobic determinants of α-defensin bactericidal activity. Infect Immun 2014 0.81
20 Inhibition of bactericidal activity is maintained in a mouse alpha-defensin precursor with proregion truncations. Peptides 2009 0.76
21 Small-angle X-ray scattering studies of peptide-lipid interactions using the mouse paneth cell α-defensin cryptdin-4. Methods Enzymol 2011 0.75