Published in Cytokine on April 07, 2011
Cancer risk by combined levels of YKL-40 and C-reactive protein in the general population. Br J Cancer (2011) 0.88
Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects. Arthritis Res Ther (2011) 0.86
Evaluation of CHI3L-1 and CHIT-1 expression in differentiated and polarized macrophages. Inflammation (2013) 0.86
Diagnostic and Prognostic Impact of Circulating YKL-40, IL-6, and CA 19.9 in Patients with Pancreatic Cancer. PLoS One (2013) 0.86
Changes in the gene expression of co-cultured human fibroblast cells and osteosarcoma cells: the role of microenvironment. Oncotarget (2015) 0.85
Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease. BMC Pulm Med (2014) 0.82
Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events. J Am Heart Assoc (2014) 0.81
Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease. BMC Pulm Med (2013) 0.80
Expression of cartilage glycoprotein 39 in peripheral blood monocytes of septic rat and its role in TLR 4-NF-κB signaling pathways. Int J Clin Exp Med (2015) 0.80
Increased Obesity-Associated Circulating Levels of the Extracellular Matrix Proteins Osteopontin, Chitinase-3 Like-1 and Tenascin C Are Associated with Colon Cancer. PLoS One (2016) 0.79
Obesity and low-grade inflammation increase plasma follistatin-like 3 in humans. Mediators Inflamm (2014) 0.78
The tumor microenvironment promotes cancer progression and cell migration. Oncotarget (2016) 0.76
Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study. PLoS One (2014) 0.75
The impact of acute aerobic exercise on chitinase 3-like protein 1 and intelectin-1 expression in obesity. Exp Biol Med (Maywood) (2015) 0.75
YKL-40 in allogeneic hematopoietic cell transplantation after AML and myelodysplastic syndrome. Bone Marrow Transplant (2016) 0.75
The Effects of Ferulic Acid Against Oxidative Stress and Inflammation in Formaldehyde-Induced Hepatotoxicity. Inflammation (2016) 0.75
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest (2004) 11.05
Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults. PLoS One (2010) 6.48
Position statement. Part one: Immune function and exercise. Exerc Immunol Rev (2011) 3.69
Interleukin-6 stimulates lipolysis and fat oxidation in humans. J Clin Endocrinol Metab (2003) 2.90
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase. Diabetes (2006) 2.80
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) (2010) 2.74
Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes (2005) 2.35
Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Exp Physiol (2009) 2.27
Muscle specific microRNAs are regulated by endurance exercise in human skeletal muscle. J Physiol (2010) 2.16
Fat-specific protein 27 regulates storage of triacylglycerol. J Biol Chem (2008) 2.07
A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity. J Appl Physiol (1985) (2009) 1.99
Metabolic responses to reduced daily steps in healthy nonexercising men. JAMA (2008) 1.81
AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise. Biochem Biophys Res Commun (2004) 1.75
The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases. J Biomed Biotechnol (2010) 1.75
Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction. Diabetes (2004) 1.73
BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study. Neurobiol Learn Mem (2008) 1.68
Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes. Genome Med (2010) 1.64
Contraction-induced myokine production and release: is skeletal muscle an endocrine organ? Exerc Sport Sci Rev (2005) 1.60
Cerebral output of cytokines in patients with pneumococcal meningitis. Crit Care Med (2005) 1.51
Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes. Mech Ageing Dev (2003) 1.50
Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome. Diabetes (2006) 1.44
MicroRNA expression profiles associated with pancreatic adenocarcinoma and ampullary adenocarcinoma. Mod Pathol (2012) 1.43
High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer. Clin Cancer Res (2003) 1.42
Body composition is the main determinant for the difference in type 2 diabetes pathophysiology between Japanese and Caucasians. Diabetes Care (2013) 1.41
Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer. Cancer Res (2011) 1.41
Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle. J Physiol (2004) 1.37
Ten questions about systems biology. J Physiol (2011) 1.36
Leisure time physical activity during pregnancy and impact on gestational diabetes mellitus, pre-eclampsia, preterm delivery and birth weight: a review. Acta Obstet Gynecol Scand (2007) 1.36
Expression of interleukin-15 in human skeletal muscle effect of exercise and muscle fibre type composition. J Physiol (2007) 1.34
Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword? FEBS J (2013) 1.33
The importance of brown adipose tissue. N Engl J Med (2009) 1.31
Antioxidant supplementation does not alter endurance training adaptation. Med Sci Sports Exerc (2010) 1.30
YKL-40 is elevated in cerebrospinal fluid from patients with purulent meningitis. Clin Diagn Lab Immunol (2002) 1.29
Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers. Ann Rheum Dis (2010) 1.25
Prognostic value of PINP, bone alkaline phosphatase, CTX-I, and YKL-40 in patients with metastatic prostate carcinoma. Prostate (2006) 1.24
Association between interleukin-15 and obesity: interleukin-15 as a potential regulator of fat mass. J Clin Endocrinol Metab (2008) 1.24
The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: expected outcome from the DD2 project and two intervention studies. Clin Epidemiol (2012) 1.24
IL-6 selectively stimulates fat metabolism in human skeletal muscle. Am J Physiol Endocrinol Metab (2010) 1.24
Exercise, nutrition and immune function. J Sports Sci (2004) 1.23
Influence of TNF-alpha and IL-6 infusions on insulin sensitivity and expression of IL-18 in humans. Am J Physiol Endocrinol Metab (2006) 1.22
Low-level viremia and proviral DNA impede immune reconstitution in HIV-1-infected patients receiving highly active antiretroviral therapy. J Infect Dis (2004) 1.22
Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals. Exp Physiol (2009) 1.22
Glucose ingestion attenuates interleukin-6 release from contracting skeletal muscle in humans. J Physiol (2003) 1.22
Expression of YKL-40 by peritumoral macrophages in human small cell lung cancer. Lung Cancer (2005) 1.22
Tumor necrosis factor-alpha modulates human in vivo lipolysis. J Clin Endocrinol Metab (2007) 1.20
Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? FASEB J (2007) 1.19
Exercise induces a marked increase in plasma follistatin: evidence that follistatin is a contraction-induced hepatokine. Endocrinology (2010) 1.18
High serum YKL-40 level after surgery for colorectal carcinoma is related to short survival. Cancer (2002) 1.18
Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle. Diabetes (2011) 1.18
Serum levels of YKL-40 and PIIINP as prognostic markers in patients with alcoholic liver disease. J Hepatol (2003) 1.18
Pre-analytical and biological variability in circulating interleukin 6 in healthy subjects and patients with rheumatoid arthritis. Biomarkers (2008) 1.18
The effects of free-living interval-walking training on glycemic control, body composition, and physical fitness in type 2 diabetic patients: a randomized, controlled trial. Diabetes Care (2012) 1.18
Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness? Am J Physiol Regul Integr Comp Physiol (2009) 1.16
Cholinergic status modulations in human volunteers under acute inflammation. J Mol Med (Berl) (2007) 1.15
Elevated NF-κB activation is conserved in human myocytes cultured from obese type 2 diabetic patients and attenuated by AMP-activated protein kinase. Diabetes (2011) 1.15
Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects. Pflugers Arch (2003) 1.15
Plasma YKL-40: a BMI-independent marker of type 2 diabetes. Diabetes (2008) 1.14
Prognostic microRNAs in cancer tissue from patients operated for pancreatic cancer--five microRNAs in a prognostic index. World J Surg (2012) 1.14
Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans. Clin Immunol (2005) 1.13
Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity. J Clin Endocrinol Metab (2012) 1.12
High serum YKL-40 concentration is associated with cardiovascular and all-cause mortality in patients with stable coronary artery disease. Eur Heart J (2009) 1.12
Effect of exercise, training, and glycogen availability on IL-6 receptor expression in human skeletal muscle. J Appl Physiol (1985) (2005) 1.12
Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults. AIDS (2007) 1.11
Glucose ingestion during endurance training does not alter adaptation. J Appl Physiol (1985) (2009) 1.10
Regulation of YKL-40 expression during genotoxic or microenvironmental stress in human glioblastoma cells. Cancer Sci (2005) 1.10
Retinol-binding protein 4 and insulin resistance. N Engl J Med (2006) 1.09
High plasma YKL-40 level in patients with ovarian cancer stage III is related to shorter survival. Oncol Rep (2003) 1.09
Interleukin-6 production by contracting human skeletal muscle: autocrine regulation by IL-6. Biochem Biophys Res Commun (2003) 1.08
Plasma concentrations of soluble urokinase-type plasminogen activator receptor are increased in patients with malaria and are associated with a poor clinical or a fatal outcome. J Infect Dis (2005) 1.08
Serum levels of YKL-40 increases in patients with acute myocardial infarction. Coron Artery Dis (2008) 1.08
Therapeutic dendritic cell vaccination of patients with metastatic renal cell carcinoma: a clinical phase 1/2 trial. J Immunother (2008) 1.07
ROS and myokines promote muscle adaptation to exercise. Trends Endocrinol Metab (2009) 1.07
The frequency of anti-infliximab antibodies in patients with rheumatoid arthritis treated in routine care and the associations with adverse drug reactions and treatment failure. Rheumatology (Oxford) (2013) 1.07
Plasma YKL-40 levels in healthy subjects from the general population. Clin Chim Acta (2011) 1.07
Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-6 as response biomarkers. Cancer Immunol Immunother (2007) 1.05
Skeletal muscle adaptation: training twice every second day vs. training once daily. J Appl Physiol (1985) (2004) 1.05
Serum YKL-40 predicts relapse-free and overall survival in patients with American Joint Committee on Cancer stage I and II melanoma. J Clin Oncol (2006) 1.04
Interleukin-6 markedly decreases skeletal muscle protein turnover and increases nonmuscle amino acid utilization in healthy individuals. J Clin Endocrinol Metab (2008) 1.04
High serum concentration of YKL-40 is associated with short survival in patients with acute myeloid leukemia. Clin Cancer Res (2005) 1.04
Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL. Atherosclerosis (2011) 1.03
Glucose ingestion attenuates the exercise-induced increase in circulating heat shock protein 72 and heat shock protein 60 in humans. Cell Stress Chaperones (2004) 1.02
Soluble urokinase receptor levels in plasma during 5 years of highly active antiretroviral therapy in HIV-1-infected patients. J Acquir Immune Defic Syndr (2004) 1.02
Elevated plasma YKL-40 levels and ischemic stroke in the general population. Ann Neurol (2010) 1.01
Serum level of YKL-40 is elevated in patients with Streptococcus pneumoniae bacteremia and is associated with the outcome of the disease. Scand J Infect Dis (2002) 1.00
Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis. Pharmacogenet Genomics (2012) 1.00
Fiber type specific expression of TNF-alpha, IL-6 and IL-18 in human skeletal muscles. Exerc Immunol Rev (2005) 1.00
Calprotectin--a novel marker of obesity. PLoS One (2009) 1.00
Insulin stimulates interleukin-6 and tumor necrosis factor-alpha gene expression in human subcutaneous adipose tissue. Am J Physiol Endocrinol Metab (2003) 1.00
Brain-derived neurotrophic factor predicts mortality risk in older women. J Am Geriatr Soc (2009) 1.00
Bed rest reduces metabolic protein content and abolishes exercise-induced mRNA responses in human skeletal muscle. Am J Physiol Endocrinol Metab (2011) 1.00
Elevated pretreatment serum concentration of YKL-40-An independent prognostic biomarker for poor survival in patients with metastatic nonsmall cell lung cancer. Cancer (2010) 0.99
PGC-1beta is downregulated by training in human skeletal muscle: no effect of training twice every second day vs. once daily on expression of the PGC-1 family. J Appl Physiol (1985) (2007) 0.99
Type 2 diabetes mellitus is associated with impaired cytokine response and adhesion molecule expression in human endotoxemia. Intensive Care Med (2010) 0.98