Published in J Nat Med on April 10, 2011
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling. Nat Neurosci (2003) 3.34
EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP. Nat Neurosci (2002) 2.90
Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science (2003) 2.53
Semaphorin 5A is a bifunctional axon guidance cue regulated by heparan and chondroitin sulfate proteoglycans. Neuron (2004) 2.10
NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. J Neurosci (2002) 2.03
EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1. Nat Cell Biol (2005) 2.02
Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes. Immunity (2010) 2.00
Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44. J Exp Med (2011) 1.78
Loss of heparan sulfate glycosaminoglycan assembly in podocytes does not lead to proteinuria. Kidney Int (2008) 1.73
Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function. Development (2005) 1.69
Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function. J Clin Invest (2008) 1.52
N -Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth. J Neurochem (2002) 1.51
Role of soluble receptor for advanced glycation end products on endotoxin-induced lung injury. Am J Respir Crit Care Med (2008) 1.47
Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice. Am J Respir Cell Mol Biol (2007) 1.41
Attenuation of endotoxin-induced acute lung injury by the Rho-associated kinase inhibitor, Y-27632. Am J Respir Cell Mol Biol (2005) 1.35
Overexpression of hyaluronan in the tunica media promotes the development of atherosclerosis. Circ Res (2005) 1.23
A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses. Proc Natl Acad Sci U S A (2010) 1.20
Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate. J Neurosci (2007) 1.18
Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development (2009) 1.18
Human glioblastomas overexpress ADAMTS-5 that degrades brevican. Acta Neuropathol (2005) 1.17
Evaluation of blood pressure measured by tail-cuff methods (without heating) in spontaneously hypertensive rats. Biol Pharm Bull (2006) 1.14
Polysialic acid facilitates tumor invasion by glioma cells. Glycobiology (2005) 1.13
Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis. Development (2011) 1.13
Antitumor effect of cordycepin (3'-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation. Anticancer Res (2006) 1.13
Oxidants in the gas phase of cigarette smoke pass through the lung alveolar wall and raise systemic oxidative stress. J Pharmacol Sci (2007) 1.09
Heparan sulfate is required for embryonic stem cells to exit from self-renewal. J Biol Chem (2009) 1.09
Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate. Proc Natl Acad Sci U S A (2012) 1.08
Anti-inflammatory and anti-allergic activities of hydroxylamine and related compounds. Biol Pharm Bull (2002) 1.06
Antitumour activity of cordycepin in mice. Clin Exp Pharmacol Physiol (2004) 1.04
Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells. J Biol Chem (2012) 1.03
Feeding of Ginkgo biloba extract (GBE) enhances gene expression of hepatic cytochrome P-450 and attenuates the hypotensive effect of nicardipine in rats. Life Sci (2002) 1.00
Peripheral mural cell recruitment requires cell-autonomous heparan sulfate. Blood (2009) 1.00
Small changes in lymphocyte development and activation in mice through tissue-specific alteration of heparan sulphate. Immunology (2008) 0.99
Inhibition of virulence potential of Vibrio cholerae by natural compounds. Indian J Med Res (2011) 0.99
Up-regulation of angiotensin II type 2 receptor in rat thoracic aorta by pressure-overload. J Pharmacol Exp Ther (2003) 0.98
Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones. Bone (2011) 0.98
Alpha-mangostin induces Ca2+-ATPase-dependent apoptosis via mitochondrial pathway in PC12 cells. J Pharmacol Sci (2004) 0.97
Cyclooxygenase-2 inhibitory 1,4-naphthoquinones from Impatiens balsamina L. Biol Pharm Bull (2002) 0.97
NG2 proteoglycan expression in mouse skin: altered postnatal skin development in the NG2 null mouse. J Histochem Cytochem (2007) 0.97
Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects. J Biol Chem (2010) 0.97
Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells. Invest Ophthalmol Vis Sci (2011) 0.96
Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol (2010) 0.96
Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Res (2010) 0.95
Expression of NG2 proteoglycan during endochondral and intramembranous ossification. Dev Dyn (2003) 0.95
Characterization of mouse melanoma cell lines by their mortal malignancy using an experimental metastatic model. Life Sci (2002) 0.95
Heparan sulfate regulates ephrin-A3/EphA receptor signaling. Proc Natl Acad Sci U S A (2008) 0.94
Allergy-preventive flavonoids from Xanthorrhoea hastilis. Chem Pharm Bull (Tokyo) (2007) 0.94
Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice. Bone (2013) 0.94
Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling. J Clin Invest (2009) 0.93
Cordycepin (3'-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A3 receptor followed by glycogen synthase kinase-3beta activation and cyclin D1 suppression. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.93
Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling. Dev Biol (2011) 0.93
Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol (2013) 0.91
Garcinone B reduces prostaglandin E2 release and NF-kappaB-mediated transcription in C6 rat glioma cells. Neurosci Lett (2005) 0.90
P2Y receptor-mediated Ca(2+) signaling increases human vascular endothelial cell permeability. J Pharmacol Sci (2004) 0.90
The role of hyaluronan produced by Has2 gene expression in development of the spine. Spine (Phila Pa 1976) (2011) 0.90
Effect of cordycepin (3'-deoxyadenosine) on hematogenic lung metastatic model mice. In Vivo (2005) 0.90
Evaluation of the bitterness of antibiotics using a taste sensor. J Pharm Pharmacol (2003) 0.90
Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome. J Pharmacol Sci (2008) 0.90
Allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of Lonicera japonica. Biol Pharm Bull (2011) 0.90
Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci (2006) 0.89
Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome. Nitric Oxide (2006) 0.89
Antipruritic effects of 1,4-naphthoquinones and related compounds. Biol Pharm Bull (2002) 0.89
Effects on blood pressure decrease in response to PAF of Impatiens textori MIQ. Biol Pharm Bull (2003) 0.89
Inhibitory effect of cordycepin on hematogenic metastasis of B16-F1 mouse melanoma cells accelerated by adenosine-5'-diphosphate. Anticancer Res (2009) 0.88
Peroxynitrite-mediated oxidative modification of low-density lipoprotein by aqueous extracts of cigarette smoke and the preventive effect of fluvastatin. Atherosclerosis (2004) 0.88
Effect of PKC412, a selective inhibitor of protein kinase C, on lung metastasis in mice injected with B16 melanoma cells. Life Sci (2003) 0.88
Fisetin inhibits osteoclastogenesis through prevention of RANKL-induced ROS production by Nrf2-mediated up-regulation of phase II antioxidant enzymes. J Pharmacol Sci (2013) 0.87
Zoosporicidal activities of anacardic acids against Aphanomyces cochlioides. Z Naturforsch C (2002) 0.87
Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space. J Neurosci (2014) 0.87
Disturbances in nitric oxide/cyclic guanosine monophosphate system in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci (2005) 0.87
Loss of β-catenin induces multifocal periosteal chondroma-like masses in mice. Am J Pathol (2012) 0.87
Biochemical evidence of atherosclerosis progression mediated by increased oxidative stress in apolipoprotein E-deficient spontaneously hyperlipidemic mice exposed to chronic cigarette smoke. J Pharmacol Sci (2009) 0.86
Endothelin-1 level in epithelial lining fluid of patients with acute respiratory distress syndrome. Respirology (2007) 0.85
EPHB receptor signaling in dendritic spine development. Front Biosci (2004) 0.85
Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling. Am J Physiol Gastrointest Liver Physiol (2013) 0.84
Contact between dermal papilla cells and dermal sheath cells enhances the ability of DPCs to induce hair growth. J Invest Dermatol (2010) 0.84
Combined effects of Cordyceps sinensis and methotrexate on hematogenic lung metastasis in mice. Receptors Channels (2003) 0.83