Randall F Holcombe

Author PubWeight™ 29.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness. Cancer Res 2005 1.55
2 Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity in patients with metastatic colorectal cancer receiving chemotherapy. Cancer Cell Int 2012 1.44
3 Wnt signaling and colon carcinogenesis: beyond APC. J Carcinog 2011 1.44
4 Expression of Wnt genes and frizzled 1 and 2 receptors in normal breast epithelium and infiltrating breast carcinoma. Int J Oncol 2004 1.35
5 WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells. Mol Cancer Ther 2009 1.34
6 Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: implications for colon cancer prevention. Mol Nutr Food Res 2008 1.24
7 Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells. J Orthop Res 2007 1.20
8 Wnt pathway-related gene expression in inflammatory bowel disease. Dig Dis Sci 2007 1.15
9 Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer. Cancer Manag Res 2009 1.05
10 Wnt pathway component LEF1 mediates tumor cell invasion and is expressed in human and murine breast cancers lacking ErbB2 (her-2/neu) overexpression. Int J Oncol 2005 1.04
11 Endoscopic ultrasound delivery of an antitumor agent to treat a case of pancreatic cancer. Nat Clin Pract Gastroenterol Hepatol 2008 0.94
12 Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells. BMC Cell Biol 2007 0.92
13 Role of canonical Wnt signaling in endometrial carcinogenesis. Expert Rev Anticancer Ther 2012 0.89
14 Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease. Oncol Rep 2007 0.88
15 A phase II trial of gemcitabine and capecitabine in patients with unresectable or metastatic gallbladder cancer or cholangiocarcinoma: Southwest Oncology Group study S0202. Cancer Chemother Pharmacol 2011 0.88
16 Differentiation of tubular and villous adenomas based on Wnt pathway-related gene expression profiles. Int J Mol Med 2010 0.87
17 Expression of the Wnt antagonist Dickkopf-3 is associated with prognostic clinicopathologic characteristics and impairs proliferation and invasion in endometrial cancer. Gynecol Oncol 2012 0.86
18 Stevens-Johnson syndrome/toxic epidermal necrolysis in a patient receiving concurrent radiation and gemcitabine. Anticancer Drugs 2003 0.86
19 Delayed oxaliplatin-associated neurotoxicity following adjuvant chemotherapy for stage III colon cancer. Anticancer Drugs 2006 0.85
20 Differential effects of wine consumption on colorectal cancer outcomes based on family history of the disease. Nutr Cancer 2007 0.84
21 Invasive colon cancer, but not non-invasive adenomas induce a gradient effect of Wnt pathway receptor frizzled 1 (Fz1) expression in the tumor microenvironment. J Transl Med 2013 0.81
22 PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma. Cancer Chemother Pharmacol 2011 0.81
23 Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumors. Cancer Chemother Pharmacol 2014 0.79
24 Coculture methodologies for the study of Wnt signals. Methods Mol Biol 2008 0.77
25 Clinical pathways for pancreatic neuroendocrine tumors. J Gastrointest Cancer 2012 0.76
26 Implementation of electronic chemotherapy ordering: an opportunity to improve evidence-based oncology care. J Oncol Pract 2013 0.76
27 Sweet's syndrome in a patient with metastatic melanoma after ipilimumab therapy. Melanoma Res 2013 0.76
28 Standardized cancer incidence disparities in Upper Manhattan New York City neighborhoods: the role of race/ethnicity, socioeconomic status, and known risk factors. Eur J Cancer Prev 2016 0.75
29 Correction: Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity in patients with metastatic colorectal cancer receiving chemotherapy. Cancer Cell Int 2013 0.75
30 In situ hybridization to evaluate the expression of Wnt and frizzled genes in mammalian tissues. Methods Mol Biol 2008 0.75
31 SW480 colorectal cancer cells that naturally express Lgr5 are more sensitive to the most common chemotherapeutic agents than Lgr5-negative SW480 cells. Anticancer Drugs 2015 0.75
32 Developing clinical research incentives for academic oncologists. J Med Pract Manage 2015 0.75
33 Does Hospital Size Affect Patient Satisfaction? Qual Manag Health Care 2017 0.75
34 Limitations of ADAMTS-13 activity level in diagnosing thrombotic thrombocytopenic purpura in pregnancy. Clin Appl Thromb Hemost 2008 0.75
35 Capecitabine in advanced gastric or oesophagogastric cancer: a viewpoint by Sai-Hong Ignatius Ou and Randall F. Holcombe. Drugs 2007 0.75