Published in Self Nonself on October 01, 2010
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature (1985) 30.47
HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science (1996) 26.19
Identification of a major co-receptor for primary isolates of HIV-1. Nature (1996) 23.81
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell (1986) 22.26
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature (1985) 21.57
CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science (1996) 18.53
SH2 domains recognize specific phosphopeptide sequences. Cell (1993) 17.28
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell (1996) 17.13
A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell (1996) 14.64
Recognition of microorganisms and activation of the immune response. Nature (2007) 12.99
Binding of HTLV-III/LAV to T4+ T cells by a complex of the 110K viral protein and the T4 molecule. Science (1986) 12.49
Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol (1989) 12.08
The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem (1987) 11.99
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature (1996) 11.37
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. Nature (1996) 10.27
Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell (1989) 9.82
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J Virol (1995) 9.02
Mechanisms of viral membrane fusion and its inhibition. Annu Rev Biochem (2001) 8.96
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature (1988) 8.32
Fidelity of HIV-1 reverse transcriptase. Science (1988) 8.08
The major human rhinovirus receptor is ICAM-1. Cell (1989) 7.81
Virus entry into animal cells. Adv Virus Res (1989) 7.78
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol (2000) 7.78
Antigen receptor tail clue. Nature (1989) 7.32
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat Med (1996) 7.08
Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures. J Gen Virol (2000) 7.00
The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. Immunity (1999) 6.80
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature (1991) 6.79
Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection. Proc Natl Acad Sci U S A (1993) 6.44
A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses. Cell (1989) 6.37
Innate recognition of viruses. Immunity (2007) 6.21
Viral and cellular membrane fusion proteins. Annu Rev Physiol (1990) 6.13
Membrane fusion. Science (1992) 5.91
Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition. J Virol (1997) 5.73
Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex. J Virol (1991) 5.49
Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton. Science (2003) 5.19
Fc receptor biology. Annu Rev Immunol (1997) 5.08
Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR. Science (1988) 5.00
Signalling through C-type lectin receptors: shaping immune responses. Nat Rev Immunol (2009) 4.98
Paramyxovirus fusion: a hypothesis for changes. Virology (1993) 4.98
The CD4 antigen: physiological ligand and HIV receptor. Cell (1988) 4.42
Expression of animal virus genomes. Bacteriol Rev (1971) 4.33
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell (2006) 4.13
Interferon signalling network in innate defence. Cell Microbiol (2006) 3.90
B cell antigen receptor signaling 101. Mol Immunol (2004) 3.58
The innate immune modulators staphylococcal complement inhibitor and chemotaxis inhibitory protein of Staphylococcus aureus are located on beta-hemolysin-converting bacteriophages. J Bacteriol (2006) 3.50
The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion. Cytokine Growth Factor Rev (2001) 3.34
Inhibition of lymphocyte proliferation by a synthetic peptide homologous to retroviral envelope proteins. Science (1985) 3.27
Recognition of viruses by innate immunity. Immunol Rev (2007) 3.23
cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1. Proc Natl Acad Sci U S A (1989) 3.09
The TREM receptor family and signal integration. Nat Immunol (2006) 3.06
The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies. EMBO J (1987) 3.03
New developments in FcepsilonRI regulation, function and inhibition. Nat Rev Immunol (2007) 2.99
Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity (1998) 2.95
How T cells 'see' antigen. Nat Immunol (2005) 2.87
Toll-like receptors: linking innate and adaptive immunity. Adv Exp Med Biol (2005) 2.85
The organizing principle in the formation of the T cell receptor-CD3 complex. Cell (2002) 2.74
HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization. Immunity (1994) 2.63
Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors. J Biol Chem (1998) 2.57
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response. J Exp Med (2005) 2.57
The SIRP family of receptors and immune regulation. Nat Rev Immunol (2006) 2.57
Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus. Nat Immunol (2005) 2.55
Human cell proteins and human immunodeficiency virus DNA integration. Front Biosci (2004) 2.32
Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Immunity (2001) 2.30
The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell (2003) 2.28
Principles of intracellular viral recognition. Curr Opin Immunol (2006) 2.25
Human and bovine coronaviruses recognize sialic acid-containing receptors similar to those of influenza C viruses. Proc Natl Acad Sci U S A (1988) 2.24
Mechanisms of inhibition of the host interferon alpha/beta-mediated antiviral responses by viruses. Microbes Infect (2002) 2.17
The host type I interferon response to viral and bacterial infections. Cell Res (2005) 2.12
Paired immunoglobulin-like receptors and their MHC class I recognition. Immunology (2005) 2.07
Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells. Proc Natl Acad Sci U S A (2003) 2.05
Virus membrane fusion. FEBS Lett (2007) 2.03
Selective ablation of human T-cell lymphotropic virus type 1 p12I reduces viral infectivity in vivo. Blood (1998) 2.03
Oligomeric organization of gp120 on infectious human immunodeficiency virus type 1 particles. J Virol (1990) 2.00
What studies of fusion peptides tell us about viral envelope glycoprotein-mediated membrane fusion (review). Mol Membr Biol (1998) 1.94
Fc receptors and their role in immune regulation and autoimmunity. J Clin Immunol (2005) 1.94
HIV-1 Nef increases T cell activation in a stimulus-dependent manner. Proc Natl Acad Sci U S A (1999) 1.92
Multichain immune recognition receptors: similarities in structure and signaling pathways. Immunol Today (1992) 1.90
Mechanism for down-regulation of CD28 by Nef. EMBO J (2001) 1.87
Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells. Proc Natl Acad Sci U S A (1999) 1.86
A system of viruses. Cold Spring Harb Symp Quant Biol (1962) 1.84
The assembly of diverse immune receptors is focused on a polar membrane-embedded interaction site. PLoS Biol (2006) 1.83
Immune evasion by Kaposi's sarcoma-associated herpesvirus. Nat Rev Immunol (2007) 1.78
OKT3 and IL-2 treatment for purging of the latent HIV-1 reservoir in vivo results in selective long-lasting CD4+ T cell depletion. J Clin Immunol (2001) 1.75
Transmembrane helical interactions and the assembly of the T cell receptor complex. Science (1990) 1.74
Receptor-binding characteristics of monoclonal antibody-selected antigenic variants of influenza virus. J Virol (1987) 1.70
Oligomeric structure of the human immunodeficiency virus type 1 envelope protein on the virion surface. J Virol (2002) 1.69
Influenza virus hemagglutinins differentiate between receptor determinants bearing N-acetyl-, N-glycollyl-, and N,O-diacetylneuraminic acids. Virology (1985) 1.69
The interferon regulatory factor family in host defense: mechanism of action. J Biol Chem (2007) 1.67
DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells. J Exp Med (2000) 1.59
Nef-mediated enhancement of virion infectivity and stimulation of viral replication are fundamental properties of primate lentiviruses. J Virol (2007) 1.58
Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells. J Biol Chem (1989) 1.58
The alpha-anomeric form of sialic acid is the minimal receptor determinant recognized by reovirus. Virology (1989) 1.56
Fusion peptides and the mechanism of viral fusion. Biochim Biophys Acta (2003) 1.50
Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR down-modulation. J Gen Virol (1998) 1.50
Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis. EMBO J (1999) 1.45
A human cytomegalovirus antagonist of type I IFN-dependent signal transducer and activator of transcription signaling. Proc Natl Acad Sci U S A (2006) 1.43
Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. J Immunol (2005) 1.41
HTLV-1 p12(I) protein enhances STAT5 activation and decreases the interleukin-2 requirement for proliferation of primary human peripheral blood mononuclear cells. Blood (2001) 1.38
Membrane binding of intrinsically disordered proteins: Critical importance of an appropriate membrane model. Self Nonself (2010) 0.78
The SCHOOL of nature: III. From mechanistic understanding to novel therapies. Self Nonself (2010) 0.77
The SCHOOL of nature: II. Protein order, disorder and oligomericity in transmembrane signaling. Self Nonself (2010) 0.77
Cells diversify transmembrane signaling through the controlled chaos of protein disorder. Self Nonself (2011) 0.75