Published in FASEB J on April 14, 2011
Bioorthogonal two-component drug delivery in HER2(+) breast cancer mouse models. Sci Rep (2016) 1.09
Imaging beyond the proteome. Chem Commun (Camb) (2012) 0.95
Imaging cell surface glycosylation in vivo using "double click" chemistry. Bioconjug Chem (2013) 0.94
Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations. Biotechnol Bioeng (2011) 0.92
Nutrient-deprived cancer cells preferentially use sialic acid to maintain cell surface glycosylation. Biomaterials (2015) 0.92
A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. ACS Chem Biol (2013) 0.88
Chemical probing of glycans in cells and organisms. Chem Soc Rev (2012) 0.86
Metabolic glycan imaging by isonitrile-tetrazine click chemistry. Chembiochem (2013) 0.84
P53 and cancer-associated sialylated glycans are surrogate markers of cancerization of the bladder associated with Schistosoma haematobium infection. PLoS Negl Trop Dis (2014) 0.82
Glycans in pathogenic bacteria--potential for targeted covalent therapeutics and imaging agents. Chem Commun (Camb) (2014) 0.81
A biocompatible "split luciferin" reaction and its application for non-invasive bioluminescent imaging of protease activity in living animals. Curr Protoc Chem Biol (2014) 0.80
Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clin Proteomics (2015) 0.80
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging. Angew Chem Int Ed Engl (2015) 0.78
Dual-sugar imaging using isonitrile and azido-based click chemistries. Org Biomol Chem (2013) 0.78
Development of a novel method to evaluate sialylation of glycoproteins and analysis of gp96 sialylation in Hela, SW1990 and A549 cell lines. Biol Res (2015) 0.77
Imaging the glycome in living systems. Methods Enzymol (2012) 0.76
Chemistry-enabled methods for the visualization of cell-surface glycoproteins in Metazoans. Glycoconj J (2015) 0.76
Towards in vivo imaging of cancer sialylation. Int J Mol Imaging (2011) 0.75
Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example. Biomaterials (2016) 0.75
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging. Angew Chem Weinheim Bergstr Ger (2015) 0.75
Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response. Clin Cancer Res (2016) 0.75
A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation. Chem Sci (2014) 0.75
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science (2009) 18.40
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med (2007) 6.84
Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate. Nature (2008) 5.60
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. EMBO J (2011) 2.97
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nat Genet (2011) 2.72
The biosynthesis and regulation of bacterial prodiginines. Nat Rev Microbiol (2006) 2.36
13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C-labeled glutamine. Magn Reson Med (2008) 2.34
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors. Proc Natl Acad Sci U S A (2009) 2.04
Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus. Nat Med (2012) 1.83
Kinetic modeling of hyperpolarized 13C label exchange between pyruvate and lactate in tumor cells. J Biol Chem (2011) 1.76
Magnetization transfer measurements of exchange between hyperpolarized [1-13C]pyruvate and [1-13C]lactate in a murine lymphoma. Magn Reson Med (2010) 1.74
Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1- 13C]pyruvate and 13C magnetic resonance spectroscopic imaging. Magn Reson Med (2010) 1.65
Bioluminescent imaging: a critical tool in pre-clinical oncology research. J Pathol (2010) 1.64
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation. Microbiology (2004) 1.57
Clinical proton MR spectroscopy in central nervous system disorders. Radiology (2014) 1.53
A comparison between radiolabeled fluorodeoxyglucose uptake and hyperpolarized (13)C-labeled pyruvate utilization as methods for detecting tumor response to treatment. Neoplasia (2009) 1.52
Anticancer and immunosuppressive properties of bacterial prodiginines. Future Microbiol (2007) 1.52
Proton NMR analysis of plasma is a weak predictor of coronary artery disease. Nat Med (2006) 1.49
Hyperpolarized [1-13C]-ascorbic and dehydroascorbic acid: vitamin C as a probe for imaging redox status in vivo. J Am Chem Soc (2011) 1.47
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia. J Exp Med (2013) 1.40
Assessing responses to cancer therapy using molecular imaging. Biochim Biophys Acta (2006) 1.31
Uric acid promotes tumor immune rejection. Cancer Res (2004) 1.26
Evaluation of predicted network modules in yeast metabolism using NMR-based metabolite profiling. Genome Res (2007) 1.26
1H MRS-visible lipids accumulate during apoptosis of lymphoma cells in vitro and in vivo. Magn Reson Med (2005) 1.20
Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria. Biochem J (2002) 1.19
Mitochondrial dysfunction in patients with primary congenital insulin resistance. J Clin Invest (2011) 1.19
Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy. Mol Cancer Ther (2010) 1.14
Bacterial biosynthetic gene clusters encoding the anti-cancer haterumalide class of molecules: biogenesis of the broad spectrum antifungal and anti-oomycete compound, oocydin A. J Biol Chem (2012) 1.08
Imaging pH with hyperpolarized 13C. NMR Biomed (2011) 1.08
Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells. Chem Sci (2011) 1.08
Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization. Cancer Res (2012) 1.07
Detection of tumor glutamate metabolism in vivo using (13)C magnetic resonance spectroscopy and hyperpolarized [1-(13)C]glutamate. Magn Reson Med (2011) 1.06
Detection of cell death in tumors by using MR imaging and a gadolinium-based targeted contrast agent. Radiology (2008) 1.04
Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4-acetic acid, assessed using MRI and MRS. NMR Biomed (2002) 1.03
Superparamagnetic iron oxide-labeled Schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation into the CNS. J Neurosci (2004) 1.03
What do magnetic resonance-based measurements of Pi→ATP flux tell us about skeletal muscle metabolism? Diabetes (2012) 1.02
Immune cell-induced synthesis of NO and reactive oxygen species in lymphoma cells causes their death by apoptosis. FEBS Lett (2005) 1.01
Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis. Proc Natl Acad Sci U S A (2012) 1.01
Imaging tumour cell metabolism using hyperpolarized 13C magnetic resonance spectroscopy. Biochem Soc Trans (2010) 0.98
FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis. Cancer Res (2012) 0.97
Spin echo measurements of the extravasation and tumor cell uptake of hyperpolarized [1-(13) C]lactate and [1-(13) C]pyruvate. Magn Reson Med (2012) 0.97
Comparison of the C2A domain of synaptotagmin-I and annexin-V as probes for detecting cell death. Bioconjug Chem (2010) 0.96
Probing lactate dehydrogenase activity in tumors by measuring hydrogen/deuterium exchange in hyperpolarized l-[1-(13)C,U-(2)H]lactate. J Am Chem Soc (2012) 0.95
Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse. NMR Biomed (2013) 0.94
Techniques: Visualizing apoptosis using nuclear magnetic resonance. Trends Pharmacol Sci (2003) 0.94
Characterization of a heat resistant beta-glucosidase as a new reporter in cells and mice. BMC Biol (2010) 0.94
Imaging cell surface glycosylation in vivo using "double click" chemistry. Bioconjug Chem (2013) 0.94
In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines. Chem Commun (Camb) (2011) 0.93
Imaging mouse cancer models in vivo using reporter transgenes. Cold Spring Harb Protoc (2013) 0.93
Direct enhancement of nuclear singlet order by dynamic nuclear polarization. J Am Chem Soc (2012) 0.92
Detection of transgene expression using hyperpolarized 13C urea and diffusion-weighted magnetic resonance spectroscopy. Magn Reson Med (2014) 0.92
Monitoring T-lymphocyte trafficking in tumors undergoing immune rejection. Magn Reson Med (2005) 0.92
Dual-modality gene reporter for in vivo imaging. Proc Natl Acad Sci U S A (2013) 0.91
Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate. Org Biomol Chem (2004) 0.91
Discrimination of pathogenic clinical isolates and laboratory strains of Bacillus cereus by NMR-based metabolomic profiling. FEMS Microbiol Lett (2005) 0.91
A fragment-based approach to identifying ligands for riboswitches. ACS Chem Biol (2010) 0.91
Hyperpolarized 13C MRI and PET: in vivo tumor biochemistry. J Nucl Med (2011) 0.90
Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography. Clin Cancer Res (2012) 0.90
(E,E)-1,5-Cyclooctadiene: a small and fast click-chemistry multitalent. Chem Commun (Camb) (2011) 0.90
Detection of apoptosis using the C2A domain of synaptotagmin I. Bioconjug Chem (2004) 0.89
Thiamin diphosphate in biological chemistry: analogues of thiamin diphosphate in studies of enzymes and riboswitches. FEBS J (2009) 0.89
N-glycan abnormalities in children with galactosemia. J Proteome Res (2013) 0.89
Characterization of image heterogeneity using 2D Minkowski functionals increases the sensitivity of detection of a targeted MRI contrast agent. Magn Reson Med (2009) 0.88
Imaging cell death. J Nucl Med (2014) 0.88
Inhibition of proliferative retinopathy by the anti-vascular agent combretastatin-A4. Am J Pathol (2002) 0.88
Evaluation of engineered meniscal cartilage constructs based on different scaffold geometries using magnetic resonance imaging and spectroscopy. Tissue Eng (2006) 0.87
Structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis provides insights into the structural basis for the chemoselective and enantioselective carboligation reaction. Acta Crystallogr D Biol Crystallogr (2007) 0.86
Exploring isonitrile-based click chemistry for ligation with biomolecules. Org Biomol Chem (2011) 0.86
Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. J Biol Chem (2007) 0.85
Metabolic consequences of p300 gene deletion in human colon cancer cells. Cancer Res (2006) 0.85
(13) C magnetic resonance spectroscopic imaging of hyperpolarized [1-(13) C, U-(2) H5 ] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in vivo. Magn Reson Med (2014) 0.84
Metabolic glycan imaging by isonitrile-tetrazine click chemistry. Chembiochem (2013) 0.84
Inhibition of pyruvate decarboxylase from Z. mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics. Chem Commun (Camb) (2006) 0.84
Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold. Org Biomol Chem (2008) 0.84
Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis . Biochemistry (2010) 0.84
A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography. Cancer Res (2014) 0.83
Copper-free click--a promising tool for pre-targeted PET imaging. Chem Commun (Camb) (2011) 0.83
Imaging and 'omic' methods for the molecular diagnosis of cancer. Expert Rev Mol Diagn (2010) 0.82
Oatp1 enhances bioluminescence by acting as a plasma membrane transporter for D-luciferin. Mol Imaging Biol (2014) 0.82
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex. Structure (2008) 0.82
A paramagnetic nanoprobe to detect tumor cell death using magnetic resonance imaging. Nano Lett (2007) 0.82