Published in Peptides on April 22, 2011
High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments. Biochim Biophys Acta (2014) 1.05
Cationic host defence peptides: potential as antiviral therapeutics. BioDrugs (2013) 0.92
Database-Guided Discovery of Potent Peptides to Combat HIV-1 or Superbugs. Pharmaceuticals (Basel) (2013) 0.90
The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus. PLoS One (2013) 0.88
Mechanisms and modifications of naturally occurring host defense peptides for anti-HIV microbicide development. Curr HIV Res (2012) 0.85
A comparative proteomic analysis of the soluble immune factor environment of rectal and oral mucosa. PLoS One (2014) 0.84
Cationic host defense peptides; novel antimicrobial therapeutics against Category A pathogens and emerging infections. Pathog Glob Health (2016) 0.80
Cathelicidin LL-37 and HSV-1 Corneal Infection: Peptide Versus Gene Therapy. Transl Vis Sci Technol (2014) 0.77
Cathelicidin antimicrobial peptide as a serologic marker and potential pathogenic factor in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Res Ther (2014) 0.75
A novel hemagglutinin with antiproliferative activity against tumor cells from the hallucinogenic mushroom Boletus speciosus. Biomed Res Int (2014) 0.75
HIV Infection and Compromised Mucosal Immunity: Oral Manifestations and Systemic Inflammation. Front Immunol (2017) 0.75
Development of an Analytical Method for the Rapid Quantitation of Peptides Used in Microbicide Formulations. Chromatographia (2014) 0.75
Natural antimicrobial peptides as promising anti-HIV candidates. Curr Top Pept Protein Res (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Genetic and phenotypic characterization of drug-resistant Mycobacterium tuberculosis isolates in Hong Kong. J Antimicrob Chemother (2007) 1.78
An in vitro study of ceftazidime and vancomycin concentrations in various fluid media: implications for use in treating endophthalmitis. Invest Ophthalmol Vis Sci (2002) 1.62
Protective effects of cathelicidin-encoding Lactococcus lactis in murine ulcerative colitis. J Gastroenterol Hepatol (2012) 1.53
Severe acute respiratory syndrome (SARS) in a geriatric patient with a hip fracture. A case report. J Bone Joint Surg Am (2003) 1.48
Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: an update on the molecular mechanisms. Cancer Lett (2010) 1.42
Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells. J Ethnopharmacol (2008) 1.41
A review of pinealectomy-induced melatonin-deficient animal models for the study of etiopathogenesis of adolescent idiopathic scoliosis. Int J Mol Sci (2014) 1.38
Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chin Med (2007) 1.36
Molecular basis of the redox regulation of SUMO proteases: a protective mechanism of intermolecular disulfide linkage against irreversible sulfhydryl oxidation. FASEB J (2007) 1.35
Rapid multiplex nested PCR for detection of respiratory viruses. J Clin Microbiol (2007) 1.35
Biases in human papillomavirus genotype prevalence assessment associated with commonly used consensus primers. Int J Cancer (2006) 1.33
Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. Toxicol Sci (2006) 1.27
β-Adrenergic system, a backstage manipulator regulating tumour progression and drug target in cancer therapy. Semin Cancer Biol (2013) 1.22
Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells. Toxicol Appl Pharmacol (2007) 1.22
The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response. Cell Host Microbe (2011) 1.21
Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells. Biochem Biophys Res Commun (2009) 1.16
Ribonucleases of different origins with a wide spectrum of medicinal applications. Biochim Biophys Acta (2010) 1.15
Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease. Biochem J (2006) 1.12
Immunofluorescence assay for serologic diagnosis of SARS. Emerg Infect Dis (2004) 1.09
2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, inhibits colitis-associated colorectal carcinogenesis in mice. Br J Pharmacol (2010) 1.07
Streptococcus suis in Hong Kong. Diagn Microbiol Infect Dis (2006) 1.04
Sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and HIV-1 reverse transcriptase. Peptides (2005) 1.04
Proteasome inhibition: a new therapeutic strategy to cancer treatment. Cancer Lett (2010) 1.04
First report of a novel plant lysozyme with both antifungal and antibacterial activities. Biochem Biophys Res Commun (2005) 1.02
Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells. Biochem Biophys Res Commun (2008) 1.02
Herba Epimedii: anti-oxidative properties and its medical implications. Molecules (2010) 1.02
Momordica Charantia lectin, a type II ribosome inactivating protein, exhibits antitumor activity toward human nasopharyngeal carcinoma cells in vitro and in vivo. Cancer Prev Res (Phila) (2011) 1.00
Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth. Cancer Lett (2010) 1.00
Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. Toxicol Appl Pharmacol (2008) 0.99
Macroautophagy and ERK phosphorylation counteract the antiproliferative effect of proteasome inhibitor in gastric cancer cells. Autophagy (2010) 0.98
Purification and detailed study of two clinically different human glucose 6-phosphate dehydrogenase variants, G6PD(Plymouth) and G6PD(Mahidol): Evidence for defective protein folding as the basis of disease. Mol Genet Metab (2007) 0.98
Lectins: production and practical applications. Appl Microbiol Biotechnol (2010) 0.97
Strain-typing of Lentinula edodes in China with inter simple sequence repeat markers. Appl Microbiol Biotechnol (2006) 0.96
Nociceptin inhibits acquisition of amphetamine-induced place preference and sensitization to stereotypy in rats. Eur J Pharmacol (2003) 0.96
Peptides as targeting probes against tumor vasculature for diagnosis and drug delivery. J Transl Med (2012) 0.96
Assay of pleural fluid interleukin-6, tumour necrosis factor-alpha and interferon-gamma in the diagnosis and outcome correlation of tuberculous effusion. Respir Med (2003) 0.96
Expression of ErbB receptors and their cognate ligands in gastric and colon cancer cell lines. Anticancer Res (2009) 0.96
Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein. J Virol (2013) 0.96
The MAP30 protein from bitter gourd (Momordica charantia) seeds promotes apoptosis in liver cancer cells in vitro and in vivo. Cancer Lett (2012) 0.95
Nanoliter dispensing method by degassed poly(dimethylsiloxane) microchannels and its application in protein crystallization. Anal Chem (2007) 0.95
The pharmacological actions of nicotine on the gastrointestinal tract. J Pharmacol Sci (2004) 0.95
Effects of adrenaline in human colon adenocarcinoma HT-29 cells. Life Sci (2011) 0.95
Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis. PLoS One (2012) 0.94
SUMO proteases: redox regulation and biological consequences. Antioxid Redox Signal (2009) 0.92
A new Phaseolus vulgaris lectin induces selective toxicity on human liver carcinoma Hep G2 cells. Arch Toxicol (2011) 0.92
Genetic polymorphism of ferula mushroom growing on Ferula sinkiangensis. Appl Microbiol Biotechnol (2005) 0.92
A novel peptide specifically targeting the vasculature of orthotopic colorectal cancer for imaging detection and drug delivery. J Control Release (2010) 0.91
The host defense peptide LL-37 activates the tumor-suppressing bone morphogenetic protein signaling via inhibition of proteasome in gastric cancer cells. J Cell Physiol (2010) 0.91
Antifungal action of human cathelicidin fragment (LL13-37) on Candida albicans. Peptides (2011) 0.91
E-cadherin promoter hypermethylation induced by interleukin-1beta treatment or H. pylori infection in human gastric cancer cell lines. Cancer Lett (2008) 0.90
Use of the housekeeping genes, gdh (zwf) and gki, in multilocus sequence typing to differentiate Streptococcus pneumoniae from Streptococcus mitis and Streptococcus oralis. Diagn Microbiol Infect Dis (2006) 0.90
Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells. Int J Cancer (2009) 0.90
An antifungal protein from ginger rhizomes. Biochem Biophys Res Commun (2005) 0.89
E series of prostaglandin receptor 2-mediated activation of extracellular signal-regulated kinase/activator protein-1 signaling is required for the mitogenic action of prostaglandin E2 in esophageal squamous-cell carcinoma. J Pharmacol Exp Ther (2008) 0.89
Partial sleep deprivation compromises gastric mucosal integrity in rats. Life Sci (2005) 0.89
First report of a haemagglutinin-induced apoptotic pathway in breast cancer cells. Biosci Rep (2010) 0.89
Isolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cells. PLoS One (2012) 0.88
2,3',4,4',5'-Pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules. Biochem Pharmacol (2009) 0.88
Epidemiology and outcome of Candida bloodstream infection in an intensive care unit in Hong Kong. Hong Kong Med J (2009) 0.87
Cordymin, an antifungal peptide from the medicinal fungus Cordyceps militaris. Phytomedicine (2010) 0.87
Association between Helicobacter pylori infection and interleukin 1beta polymorphism predispose to CpG island methylation in gastric cancer. Gut (2007) 0.87
Isolation of an antifungal thaumatin-like protein from kiwi fruits. Phytochemistry (2002) 0.87
In vitro and in vivo anticarcinogenic effects of RNase MC2, a ribonuclease isolated from dietary bitter gourd, toward human liver cancer cells. Int J Biochem Cell Biol (2012) 0.87
Crystal structure of activated CheY1 from Helicobacter pylori. J Bacteriol (2010) 0.87
In vitro and in vivo analyses of the biological activity of RGD peptides towards Ab Bomirski melanoma. Cell Mol Biol Lett (2003) 0.86
Immobilized metal ion affinity chromatography: a review on its applications. Appl Microbiol Biotechnol (2012) 0.86
Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice. Int J Med Sci (2006) 0.86
The dimeric and tetrameric octarepeat fragments of prion protein behave differently to its monomeric unit. Dalton Trans (2004) 0.86
Antifungal and antiviral products of marine organisms. Appl Microbiol Biotechnol (2014) 0.86
Antimicrobial susceptibility of Neisseria gonorrhoeae isolated in Jiangsu Province, China, with a focus on fluoroquinolone resistance. J Med Microbiol (2006) 0.86
Examples of peptide-peptoid hybrid serine protease inhibitors based on the trypsin inhibitor SFTI-1 with complete protease resistance at the P1-P1' reactive site. Chembiochem (2005) 0.86
Transcriptional regulation of corticotrophin releasing factor gene by furocoumarins isolated from seeds of Psoralea corylifolia. Life Sci (2008) 0.86
Isolation and characterization of a lectin with potentially exploitable activities from caper (Capparis spinosa) seeds. Biosci Rep (2009) 0.86
Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis. Int J Cancer (2012) 0.86
A mitogenic defensin from white cloud beans (Phaseolus vulgaris). Peptides (2006) 0.85
Two antifungal components isolated from Fructus Psoraleae and Folium Eucalypti Globuli by bioassay-guided purification. Am J Chin Med (2010) 0.85
Constitutive AhR activation leads to concomitant ABCG2-mediated multidrug resistance in cisplatin-resistant esophageal carcinoma cells. Mol Carcinog (2011) 0.85
A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. extralong autumn purple bean. J Agric Food Chem (2010) 0.85
Development of peptides as potential drugs for cancer therapy. Curr Pharm Des (2010) 0.85
Sunflower trypsin inhibitor 1 as a molecular scaffold for drug discovery. Curr Pharm Des (2011) 0.85
Dendrobium candidum extract increases the expression of aquaporin-5 in labial glands from patients with Sjögren's syndrome. Phytomedicine (2010) 0.85
Structural basis of FliG-FliM interaction in Helicobacter pylori. Mol Microbiol (2013) 0.85
Development and characterization of simple sequence repeat (SSR) markers for the mushroom Flammulina velutipes. J Biosci Bioeng (2010) 0.85
High-level expression of functional recombinant human butyrylcholinesterase in silkworm larvae by Bac-to-Bac system. Chem Biol Interact (2010) 0.84
Enhancement of doxorubicin cytotoxicity on human esophageal squamous cell carcinoma cells by indomethacin and 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC236) via inhibiting P-glycoprotein activity. Mol Pharmacol (2009) 0.84
Risk factors, microbiological profile, and treatment outcomes of pediatric microbial keratitis in a tertiary care hospital in Hong Kong. Am J Ophthalmol (2013) 0.84
Symbiotic in vitro seed propagation of Dendrobium: fungal and bacterial partners and their influence on plant growth and development. Planta (2015) 0.84
Extent and predictors of microbial hand contamination in a tertiary care ophthalmic outpatient practice. Invest Ophthalmol Vis Sci (2005) 0.84