Published in J Bone Miner Res on May 01, 2011
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Opposing TNF-α/IL-1β- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation. Cell Death Dis (2014) 0.81
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Three-question depression screener used for lumbar disc herniations and spinal stenosis. Spine (Phila Pa 1976) (2002) 1.55
Overcoming the immune response to permit ex vivo gene therapy for spine fusion with human type 5 adenoviral delivery of the LIM mineralization protein-1 cDNA. Spine (Phila Pa 1976) (2003) 1.53
TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc. J Biol Chem (2011) 1.39
ISSLS prize winner: LMP-1 upregulates intervertebral disc cell production of proteoglycans and BMPs in vitro and in vivo. Spine (Phila Pa 1976) (2004) 1.23
Summary statement: emerging techniques for treatment of degenerative lumbar disc disease. Spine (Phila Pa 1976) (2003) 1.20
Use of recombinant human bone morphogenetic protein-2 as an adjunct in posterolateral lumbar spine fusion: a prospective CT-scan analysis at one and two years. J Spinal Disord Tech (2006) 1.15
The efficacy of rhBMP-2 for posterolateral lumbar fusion in smokers. Spine (Phila Pa 1976) (2007) 1.14
LIM mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads. J Biol Chem (2006) 1.11
The evidence-based approach in bringing new orthopaedic devices to market. J Bone Joint Surg Am (2010) 1.06
The use of cultured bone marrow cells in type I collagen gel and porous hydroxyapatite for posterolateral lumbar spine fusion. Spine (Phila Pa 1976) (2005) 1.06
Comparison of Healos/bone marrow to INFUSE(rhBMP-2/ACS) with a collagen-ceramic sponge bulking agent as graft substitutes for lumbar spine fusion. Spine (Phila Pa 1976) (2005) 1.03
Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration. J Biol Chem (2013) 1.02
Simple carrier matrix modifications can enhance delivery of recombinant human bone morphogenetic protein-2 for posterolateral spine fusion. Spine (Phila Pa 1976) (2003) 1.02
New treatments and imaging strategies in degenerative disease of the intervertebral disks. Radiology (2012) 0.99
Stromal cell-derived factor-1 potentiates bone morphogenetic protein-2 induced bone formation. Tissue Eng Part A (2010) 0.98
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A critical guide to case series reports. Spine (Phila Pa 1976) (2003) 0.93
The influence of alendronate on spine fusion in an osteoporotic animal model. Spine (Phila Pa 1976) (2011) 0.93
Biomechanical effects of transverse partial sacrectomy on the sacroiliac joints: an in vitro human cadaveric investigation of the borderline of sacroiliac joint instability. Spine (Phila Pa 1976) (2009) 0.92
Overexpressed LIM mineralization proteins do not require LIM domains to induce bone. J Bone Miner Res (2002) 0.92
Delivery of recombinant human bone morphogenetic protein-2 using a compression-resistant matrix in posterolateral spine fusion in the rabbit and in the non-human primate. Spine (Phila Pa 1976) (2002) 0.92
Glucocorticoid regulation of human BMP-6 transcription. Bone (2004) 0.90
Modeling and analysis of molecularinteraction between Smurf1-WW2 domain and various isoforms of LIM mineralization protein. Proteins (2007) 0.90
Evidence of osteoinduction by Grafton demineralized bone matrix in nonhuman primate spinal fusion. Spine (Phila Pa 1976) (2004) 0.89
Engineering, cloning, and functional characterization of recombinant LIM mineralization protein-1 containing an N-terminal HIV-derived membrane transduction domain. Protein Expr Purif (2009) 0.89
Comparison of Smith-Petersen osteotomy and pedicle subtraction osteotomy for the correction of thoracolumbar kyphotic deformity in ankylosing spondylitis: a systematic review and meta-analysis. Spine (Phila Pa 1976) (2015) 0.89
Mechanism of bone formation with gene transfer of the cDNA encoding for the intracellular protein LMP-1. J Bone Joint Surg Am (2003) 0.88
Retention of 125I-labeled recombinant human bone morphogenetic protein-2 by biphasic calcium phosphate or a composite sponge in a rabbit posterolateral spine arthrodesis model. J Orthop Res (2002) 0.87
Development and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity. Cell Biochem Funct (2009) 0.87
The effects of bone morphogenetic protein and basic fibroblast growth factor on cultured mesenchymal stem cells for spine fusion. Spine (Phila Pa 1976) (2007) 0.87
Lower dose of rhBMP-2 achieves spine fusion when combined with an osteoconductive bulking agent in non-human primates. Spine (Phila Pa 1976) (2005) 0.87
A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype. Mol Cell Biochem (2010) 0.86
Symposium. The introduction of biologics in orthopaedics: issues of cost, commercialism, and ethics. J Bone Joint Surg Am (2007) 0.86
Biologic treatment for intervertebral disc degeneration: summary statement. Spine (Phila Pa 1976) (2003) 0.84
Both expression of cytokines and posterior annulus fibrosus rupture are essential for pain behavior changes induced by degenerative intervertebral disc: An experimental study in rats. J Orthop Res (2013) 0.84
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BMPs and gene therapy for spinal fusion: summary statement. Spine (Phila Pa 1976) (2003) 0.82
Natural antisense transcripts enhance bone formation by increasing sense IFITM5 transcription. Bone (2012) 0.82
A comparison of static near stereo acuity in youth baseball/softball players and non-ball players. Optometry (2009) 0.81
Physical function measurements in neck pain. Phys Med Rehabil Clin N Am (2003) 0.81
Emerging technology in spine: should we rethink the past or move forward in spite of the past? Spine (Phila Pa 1976) (2003) 0.80
Purified bovine BMP extract and collagen for spine arthrodesis: preclinical safety and efficacy. Spine (Phila Pa 1976) (2002) 0.80
Truncated human LMP-1 triggers differentiation of C2C12 cells to an osteoblastic phenotype in vitro. Acta Biochim Biophys Sin (Shanghai) (2007) 0.80
Outcome research in patients with chronic low back pain. Orthop Clin North Am (2003) 0.79
Do the adjacent level intervertebral discs degenerate after a lumbar spinal fusion? An experimental study using a rabbit model. Spine (Phila Pa 1976) (2010) 0.79
Use of recombinant human bone morphogenetic protein-2 with local bone graft instead of iliac crest bone graft in posterolateral lumbar spine arthrodesis. Spine (Phila Pa 1976) (2013) 0.79
Posterolateral Lumbar Arthrodesis With and Without Interbody Arthrodesis for L4-L5 Degenerative Spondylolisthesis: A Comparative Value Analysis. Spine (Phila Pa 1976) (2015) 0.79
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A novel low-molecular-weight compound enhances ectopic bone formation and fracture repair. J Bone Joint Surg Am (2013) 0.78
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Main thoracic curve adolescent idiopathic scoliosis: association of higher rod stiffness and concave-side pedicle screw density with improvement in sagittal thoracic kyphosis restoration. J Neurosurg Spine (2014) 0.78
Pelvic retroversion is the key protective mechanism of L4-5 degenerative spondylolisthesis. Eur Spine J (2014) 0.78
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Osteoinductive LIM mineralization protein-1 suppresses activation of NF-kappaB and selectively regulates MAPK pathways in pre-osteoclasts. Bone (2009) 0.78
AOA Symposium. Orthopaedists partnering with other physicians to provide musculoskeletal care. J Bone Joint Surg Am (2007) 0.78
LIM mineralization protein-1 suppresses TNF-α induced intervertebral disc degeneration by maintaining nucleus pulposus extracellular matrix production and inhibiting matrix metalloproteinases expression. J Orthop Res (2014) 0.78
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rhBMP-2 enhancement of posterolateral spinal fusion in a rabbit model in the presence of concurrently administered doxorubicin. Spine J (2006) 0.77
The effects of doxorubicin (adriamycin) on spinal fusion: an experimental model of posterolateral lumbar spinal arthrodesis. Spine J (2004) 0.77
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An analysis of spinopelvic sagittal alignment after lumbar lordosis reconstruction for degenerative spinal diseases: how much balance can be obtained? Spine (Phila Pa 1976) (2014) 0.77
[Advancement in the repair and reconstruction of the injured spine and spinal cord]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2006) 0.76
Biomechanical effect of 4-rod technique on lumbosacral fixation: an in vitro human cadaveric investigation. Spine (Phila Pa 1976) (2013) 0.76
Gene therapy applications for spine fusion. Spine (Phila Pa 1976) (2003) 0.76
HBV reactivation in an occult HBV infection patient treated with prednisone for nephrotic syndrome: case report and literature review. BMC Infect Dis (2013) 0.76