Rudolf A de Boer

Author PubWeight™ 114.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet 2013 3.87
2 Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet 2010 3.55
3 New gene functions in megakaryopoiesis and platelet formation. Nature 2011 3.14
4 Common variants near TERC are associated with mean telomere length. Nat Genet 2010 2.98
5 Seventy-five genetic loci influencing the human red blood cell. Nature 2012 2.77
6 Telomere length of circulating leukocytes is decreased in patients with chronic heart failure. J Am Coll Cardiol 2007 2.36
7 Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND. Eur Heart J 2013 2.32
8 Universal risk factors for multifactorial diseases: LifeLines: a three-generation population-based study. Eur J Epidemiol 2007 2.18
9 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
10 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet 2013 1.72
11 Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A. Arterioscler Thromb Vasc Biol 2010 1.68
12 Genetic and pharmacological inhibition of galectin-3 prevents cardiac remodeling by interfering with myocardial fibrogenesis. Circ Heart Fail 2012 1.67
13 Erythropoietin stimulates normal endothelial progenitor cell-mediated endothelial turnover, but attributes to neovascularization only in the presence of local ischemia. Cardiovasc Drugs Ther 2008 1.57
14 Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy. Eur J Heart Fail 2012 1.51
15 Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction. Stem Cells 2009 1.50
16 Left-dominant arrhythmogenic cardiomyopathy in a large family: associated desmosomal or nondesmosomal genotype? Heart Rhythm 2012 1.46
17 Suicidal erythrocyte death, eryptosis, as a novel mechanism in heart failure-associated anaemia. Cardiovasc Res 2013 1.43
18 Telomere biology in healthy aging and disease. Pflugers Arch 2009 1.41
19 An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study. Eur J Heart Fail 2003 1.41
20 Vitamin D status and outcomes in heart failure patients. Eur J Heart Fail 2011 1.40
21 Galectin-3 mediates aldosterone-induced vascular fibrosis. Arterioscler Thromb Vasc Biol 2012 1.37
22 Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase. Am J Physiol Renal Physiol 2006 1.36
23 Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway. Am J Pathol 2011 1.30
24 Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms. Hum Mol Genet 2009 1.25
25 The cardioprotective effects of metformin. Curr Opin Lipidol 2011 1.19
26 Physiological interaction of heart and lung in thoracic irradiation. Int J Radiat Oncol Biol Phys 2012 1.19
27 Prognostic value of changes in galectin-3 levels over time in patients with heart failure: data from CORONA and COACH. Circ Heart Fail 2013 1.16
28 Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure. Cardiovasc Diabetol 2011 1.14
29 Liver X receptors alpha and beta regulate renin expression in vivo. J Clin Invest 2005 1.13
30 The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload. J Steroid Biochem Mol Biol 2012 1.10
31 Metformin improves cardiac function in a nondiabetic rat model of post-MI heart failure. Am J Physiol Heart Circ Physiol 2011 1.10
32 Genetic analysis in 418 index patients with idiopathic dilated cardiomyopathy: overview of 10 years' experience. Eur J Heart Fail 2013 1.05
33 Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT). Am Heart J 2011 1.04
34 Telomere length and psychological well-being in patients with chronic heart failure. Age Ageing 2010 1.04
35 Aging, telomeres and heart failure. Heart Fail Rev 2010 1.02
36 Galectin-3 is an independent marker for ventricular remodeling and mortality in patients with chronic heart failure. Clin Res Cardiol 2012 1.01
37 Short-term vitamin D3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: an open-label, blinded end point, randomized prospective trial (VitD-CHF trial). Am Heart J 2013 1.01
38 Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure. Cardiovasc Res 2010 1.00
39 Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circ Cardiovasc Genet 2011 0.99
40 Telomere biology in cardiovascular disease: the TERC-/- mouse as a model for heart failure and ageing. Cardiovasc Res 2008 0.99
41 New roles for renin and prorenin in heart failure and cardiorenal crosstalk. Heart Fail Rev 2012 0.98
42 Telomere length of circulating leukocyte subpopulations and buccal cells in patients with ischemic heart failure and their offspring. PLoS One 2011 0.97
43 Bone marrow dysfunction in chronic heart failure patients. Eur J Heart Fail 2010 0.97
44 Possible association between telomere length and renal dysfunction in patients with chronic heart failure. Am J Cardiol 2008 0.97
45 Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy. Arterioscler Thromb Vasc Biol 2011 0.95
46 Erythropoietin improves left ventricular function and coronary flow in an experimental model of ischemia-reperfusion injury. Eur J Heart Fail 2004 0.95
47 Metformin in non-diabetic patients presenting with ST elevation myocardial infarction: rationale and design of the glycometabolic intervention as adjunct to primary percutaneous intervention in ST elevation myocardial infarction (GIPS)-III trial. Cardiovasc Drugs Ther 2012 0.94
48 Activation of liver X receptor-alpha reduces activation of the renal and cardiac renin-angiotensin-aldosterone system. Lab Invest 2010 0.94
49 The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro. PLoS One 2010 0.93
50 Incremental prognostic power of novel biomarkers (growth-differentiation factor-15, high-sensitivity C-reactive protein, galectin-3, and high-sensitivity troponin-T) in patients with advanced chronic heart failure. Am J Cardiol 2013 0.92
51 Diabetes, glycemic control, and new-onset heart failure in patients with stable coronary artery disease: data from the heart and soul study. Diabetes Care 2010 0.91
52 Telomere length and outcome in heart failure. Ann Med 2010 0.90
53 Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism. PLoS One 2013 0.90
54 Sex differences in new-onset heart failure. Clin Res Cardiol 2014 0.89
55 A role for CETP TaqIB polymorphism in determining susceptibility to atrial fibrillation: a nested case control study. BMC Med Genet 2006 0.89
56 The emerging role of telomere biology in cardiovascular disease. Front Biosci (Landmark Ed) 2010 0.89
57 Sustained postoperative anaemia is associated with an impaired outcome after coronary artery bypass graft surgery: insights from the IMAGINE trial. Heart 2011 0.88
58 Identification of hypertrophy- and heart failure-associated genes by combining in vitro and in vivo models. Physiol Genomics 2012 0.88
59 Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo. Eur J Heart Fail 2010 0.88
60 Increased soluble ST2 predicts long-term mortality in patients with stable coronary artery disease: results from the Ludwigshafen risk and cardiovascular health study. Clin Chem 2014 0.88
61 Anaemia among patients with heart failure and preserved or reduced ejection fraction: results from the SENIORS study. Eur J Heart Fail 2011 0.87
62 AKIP1 expression modulates mitochondrial function in rat neonatal cardiomyocytes. PLoS One 2013 0.86
63 Pharmacoepigenetics in heart failure. Curr Heart Fail Rep 2010 0.86
64 Can critically short telomeres cause functional exhaustion of progenitor cells in postinfarction heart failure? J Am Coll Cardiol 2007 0.86
65 Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1. Hypertension 2013 0.86
66 Renal dysfunction is associated with shorter telomere length in heart failure. Clin Res Cardiol 2009 0.85
67 Anaemia is associated with shorter leucocyte telomere length in patients with chronic heart failure. Eur J Heart Fail 2010 0.85
68 Telomere biology in heart failure. Eur J Heart Fail 2008 0.85
69 Animal models of cardiorenal syndrome: a review. Heart Fail Rev 2012 0.84
70 Vitamin D deficiency: universal risk factor for multifactorial diseases? Curr Drug Targets 2011 0.83
71 Erythropoietin in cardiac disease: new features of an old drug. Eur J Pharmacol 2008 0.83
72 Influence of age on the prognostic value of mid-regional pro-adrenomedullin in the general population. Heart 2012 0.83
73 Association between glycated haemoglobin and the risk of congestive heart failure in diabetes mellitus: systematic review and meta-analysis. Eur J Heart Fail 2012 0.83
74 A review on the putative association between beta-blockers and depression. Heart Fail Clin 2011 0.83
75 The ARCHITECT galectin-3 assay: comparison with other automated and manual assays for the measurement of circulating galectin-3 levels in heart failure. Expert Rev Mol Diagn 2014 0.82
76 Anemia in chronic heart failure: etiology and treatment options. Curr Opin Cardiol 2008 0.82
77 Estradiol-induced, endothelial progenitor cell-mediated neovascularization in male mice with hind-limb ischemia. Vasc Med 2009 0.82
78 Heart failure-associated anemia: bone marrow dysfunction and response to erythropoietin. J Mol Med (Berl) 2010 0.82
79 DHRS7c, a novel cardiomyocyte-expressed gene that is down-regulated by adrenergic stimulation and in heart failure. Eur J Heart Fail 2011 0.82
80 AKIP1, a cardiac hypertrophy induced protein that stimulates cardiomyocyte growth via the Akt pathway. Int J Mol Sci 2013 0.81
81 Nuclear hormone receptors as regulators of the renin-angiotensin-aldosterone system. Hypertension 2008 0.80
82 The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects. Eur J Heart Fail 2015 0.80
83 Biomarkers for risk prediction in acute decompensated heart failure. Curr Heart Fail Rep 2014 0.79
84 Sodium restriction on top of renin-angiotensin-aldosterone system blockade increases circulating levels of N-acetyl-seryl-aspartyl-lysyl-proline in chronic kidney disease patients. J Hypertens 2013 0.79
85 Regulation of the (pro)renin-renin receptor in cardiac remodelling. J Cell Mol Med 2012 0.79
86 Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity. Atherosclerosis 2013 0.79
87 Prognostic value of renin and prorenin in heart failure patients with decreased kidney function. Am Heart J 2011 0.79
88 Rapid bedside measurement of brain natriuretic peptide in patients with chronic heart failure. Int J Cardiol 2002 0.78
89 Myostatin: an overlooked player in heart failure? Eur J Heart Fail 2010 0.78
90 Heart failure, aging and beta-blockers: the need for more data on tolerability and efficacy. Clin Res Cardiol 2008 0.78
91 Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes. Circ Cardiovasc Genet 2014 0.78
92 Specific MAP-kinase blockade protects against renal damage in homozygous TGR(mRen2)27 rats. Lab Invest 2003 0.77
93 Renal effects of long-term darbepoetin alpha treatment in hypertensive TGR(mRen2)27 rats. J Renin Angiotensin Aldosterone Syst 2012 0.77
94 Statins in the treatment of heart failure. Circ Heart Fail 2010 0.76
95 Variable effects of anti-diabetic drugs in animal models of myocardial ischemia and remodeling: a translational perspective for the cardiologist. Int J Cardiol 2013 0.76
96 Should erythropoietin treatment in chronic heart failure be haemoglobin targeted? Eur J Heart Fail 2010 0.76
97 Galectin-3 and left ventricular reverse remodelling after surgical mitral valve repair. Eur J Heart Fail 2013 0.76
98 Anemia is associated with an increased central venous pressure and mortality in a broad spectrum of cardiovascular patients. Clin Res Cardiol 2014 0.75
99 Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure: A Scientific Statement From the American Heart Association. Circulation 2017 0.75
100 Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA). Eur J Heart Fail 2015 0.75
101 Brugada syndrome or Brugada electrocardiogram? J Am Coll Cardiol 2009 0.75
102 ACE-inhibitors, beta-blockers or the combination in heart failure: is it just an A-B-C ? : editorial to: effects of beta-blockade and ACE inhibition on B-type natriuretic peptides in stable patients with systolic heart failure by Rosenberg et al. Cardiovasc Drugs Ther 2008 0.75
103 Letter by de Boer and van Veldhuisen regarding article, "Risk of thromboembolism in heart failure: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT)". Circulation 2008 0.75
104 Stem cells in heart failure. Eur J Heart Fail 2010 0.75
105 Low-dose digoxin in heart failure. Int J Cardiol 2008 0.75
106 Erythropoiesis stimulation in acute ischemic syndromes. Heart Fail Clin 2010 0.75
107 Meeting highlights from the 2010 European society of cardiology heart failure association winter meeting: translational heart failure research. Eur J Heart Fail 2010 0.75
108 Clinical trials update from the European Society of Cardiology Meeting 2011: ARISTOTLE, SMART-AV: QLV substudy, SHIFT: echocardiography and quality of life substudies, European CRT Survey, and Basic Science Update. Eur J Heart Fail 2011 0.75
109 The Nobel Prize for medicine for telomere biology and relevance to heart failure research. Eur J Heart Fail 2009 0.75
110 New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circ Cardiovasc Genet 2017 0.75
111 Plasma galectin-3 concentrations in patients with primary aldosteronism. J Hypertens 2017 0.75