Terrance J Kavanagh

Author PubWeight™ 70.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods 2005 6.23
2 Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase. Mol Aspects Med 2008 1.92
3 Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice. Toxicol Sci 2007 1.60
4 Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect 2013 1.52
5 Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity. Anal Biochem 2003 1.46
6 Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress. Arch Biochem Biophys 2004 1.29
7 Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements. Circ Res 2003 1.20
8 TGFbeta1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms. FASEB J 2003 1.18
9 Changes in atherosclerotic plaques induced by inhalation of diesel exhaust. Atherosclerosis 2011 1.12
10 Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels. Toxicol Appl Pharmacol 2008 1.10
11 Glutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset. Autoimmunity 2005 1.09
12 Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicol Appl Pharmacol 2006 1.07
13 Variants in the glutamate-cysteine-ligase gene are associated with cystic fibrosis lung disease. Am J Respir Crit Care Med 2006 1.06
14 Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis. Free Radic Biol Med 2004 1.05
15 Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. Toxicol Sci 2007 1.04
16 Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death. Am J Pathol 2002 1.04
17 Rapid activation of glutamate cysteine ligase following oxidative stress. J Biol Chem 2010 1.04
18 Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice. J Biol Chem 2006 1.02
19 Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice. Aging Cell 2013 1.02
20 The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner. PLoS One 2011 1.01
21 Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells. Toxicol Sci 2007 0.98
22 Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice. Lab Invest 2010 0.97
23 Modulating GSH synthesis using glutamate cysteine ligase transgenic and gene-targeted mice. Drug Metab Rev 2008 0.97
24 DIESEL particulate exposed macrophages alter endothelial cell expression of eNOS, iNOS, MCP1, and glutathione synthesis genes. Toxicol In Vitro 2011 0.95
25 Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis model. Free Radic Biol Med 2012 0.94
26 Adenoviral overexpression of the glutamylcysteine ligase catalytic subunit protects pancreatic islets against oxidative stress. J Biol Chem 2004 0.94
27 The role of mitochondrial and oxidative injury in BDE 47 toxicity to human fetal liver hematopoietic stem cells. Toxicol Sci 2007 0.92
28 Biomineralization and size control of stable calcium phosphate core-protein shell nanoparticles: potential for vaccine applications. Bioconjug Chem 2012 0.92
29 In vitro toxicity assessment of amphiphillic polymer-coated CdSe/ZnS quantum dots in two human liver cell models. ACS Nano 2012 0.91
30 Heme oxygenase expression as a biomarker of exposure to amphiphilic polymer-coated CdSe/ZnS quantum dots. Nanotoxicology 2012 0.90
31 Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes. Free Radic Biol Med 2009 0.88
32 A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age. Environ Res 2010 0.88
33 Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71. Neurotoxicology 2008 0.87
34 Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice. Inhal Toxicol 2011 0.87
35 Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity. Toxicol Sci 2005 0.87
36 Homocysteine stimulates antioxidant response element-mediated expression of glutamate-cysteine ligase in mouse macrophages. Atherosclerosis 2008 0.87
37 Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice. Free Radic Biol Med 2012 0.86
38 Over expression of glutamate cysteine ligase increases cellular resistance to H2O2-induced DNA single-strand breaks. Cytometry A 2007 0.85
39 Exposure to diesel exhaust up-regulates iNOS expression in ApoE knockout mice. Toxicol Appl Pharmacol 2011 0.85
40 Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting. Chem Res Toxicol 2011 0.85
41 Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice. Endocrinology 2011 0.84
42 Maternal and early postnatal polychlorinated biphenyl exposure in relation to total serum immunoglobulin concentrations in 6-month-old infants. J Immunotoxicol 2011 0.84
43 Chronic beryllium disease and glutathione biosynthesis genes. J Occup Environ Med 2006 0.84
44 Increased sensitivity to testicular toxicity of transplacental benzo[a]pyrene exposure in male glutamate cysteine ligase modifier subunit knockout (Gclm-/-) mice. Toxicol Sci 2012 0.83
45 Glutathione-deficient mice have increased sensitivity to transplacental benzo[a]pyrene-induced premature ovarian failure and ovarian tumorigenesis. Cancer Res 2012 0.83
46 ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway. Free Radic Biol Med 2010 0.83
47 Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress. J Toxicol 2011 0.83
48 Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells. J Neurochem 2009 0.83
49 Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. Mol Reprod Dev 2003 0.81
50 Control of angiogenesis dictated by picomolar superoxide levels. Free Radic Biol Med 2013 0.81
51 Glutathione deficiency in Gclm null mice results in complex I inhibition and dopamine depletion following paraquat administration. Toxicol Sci 2013 0.81
52 Glutathione (GSH) and the GSH synthesis gene Gclm modulate plasma redox and vascular responses to acute diesel exhaust inhalation in mice. Inhal Toxicol 2013 0.80
53 Protein tyrosine nitration of mitochondrial carbamoyl phosphate synthetase 1 and its functional consequences. Biochem Biophys Res Commun 2012 0.80
54 The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice. PLoS One 2013 0.80
55 Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress. Free Radic Biol Med 2007 0.80
56 Expression of glutamate-cysteine ligase during mouse development. Mol Reprod Dev 2002 0.80
57 Gain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 2011 0.80
58 Flow cytometric analysis of BDE 47 mediated injury to rainbow trout gill epithelial cells. Aquat Toxicol 2009 0.79
59 Glutathione S-transferase P1-1 expression modulates sensitivity of human kidney 293 cells to photodynamic therapy with hypericin. Arch Biochem Biophys 2006 0.79
60 Luminescent quantum dots for molecular toxicology. Adv Exp Med Biol 2012 0.78
61 Optimization and application of glutamate cysteine ligase measurement in wildlife species. Ecotoxicol Environ Saf 2008 0.78
62 Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development. Reprod Toxicol 2004 0.78
63 Amphiphilic polymer-coated CdSe/ZnS quantum dots induce pro-inflammatory cytokine expression in mouse lung epithelial cells and macrophages. Nanotoxicology 2014 0.77
64 Exposure to diesel exhaust upregulates COX-2 expression in ApoE knockout mice. Inhal Toxicol 2012 0.76
65 Fluorescent assessment of intracellular calcium in individual cells. Methods Mol Biol 2011 0.76
66 Measurements of astrocyte proliferation. Methods Mol Biol 2011 0.76
67 Stereoselective effects of 4-hydroxynonenal in cultured mouse hepatocytes. Chem Res Toxicol 2010 0.75
68 Glutamate cysteine ligase (GCL) transgenic and gene-targeted mice for controlling glutathione synthesis. Curr Protoc Toxicol 2009 0.75
69 Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione. Toxicol Sci 2013 0.75
70 In vitro approaches to assessing the toxicity of quantum dots. Methods Mol Biol 2014 0.75
71 In vivo approaches to assessing the toxicity of quantum dots. Methods Mol Biol 2014 0.75
72 Glycophorin A is a potential biomarker for the mutagenic effects of pesticides. Int J Occup Environ Health 2004 0.75