Published in Br J Dermatol on July 11, 2011
One remarkable molecule: filaggrin. J Invest Dermatol (2011) 2.10
Th2 Cytokines and Atopic Dermatitis. J Clin Cell Immunol (2011) 1.91
Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis. J Allergy Clin Immunol (2012) 1.56
Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases. J Clin Invest (2012) 1.38
Cytokines and the skin barrier. Int J Mol Sci (2013) 0.96
Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis. J Allergy Clin Immunol (2014) 0.96
Advances in atopic dermatitis. Curr Opin Immunol (2011) 0.95
Skin barrier defects in atopic dermatitis. Curr Allergy Asthma Rep (2014) 0.91
Serum levels of selected Th17 and Th22 cytokines in psoriatic patients. Dis Markers (2013) 0.91
Regulation of T Cell Immunity in Atopic Dermatitis by Microbes: The Yin and Yang of Cutaneous Inflammation. Front Immunol (2015) 0.84
Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase. Sci Transl Med (2016) 0.80
Vitamin d, the cutaneous barrier, antimicrobial peptides and allergies: is there a link? Allergy Asthma Immunol Res (2013) 0.80
Comparative genomic profiling of synovium versus skin lesions in psoriatic arthritis. Arthritis Rheumatol (2015) 0.78
Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses: part II of a prospective cohort study. Contact Dermatitis (2013) 0.76
Molecular Mechanisms of Cutaneous Inflammatory Disorder: Atopic Dermatitis. Int J Mol Sci (2016) 0.76
Histamine and Skin Barrier: Are Histamine Antagonists Useful for the Prevention or Treatment of Atopic Dermatitis? J Clin Med (2015) 0.76
Molecular Genetic of Atopic dermatitis: An Update. Int J Health Sci (Qassim) (2016) 0.75
Genetic Basis of Irritant Susceptibility in Health Care Workers. J Occup Environ Med (2016) 0.75
Atopic Dermatitis Studies through In Vitro Models. Front Med (Lausanne) (2017) 0.75
Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature (2001) 7.90
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature (1998) 7.12
HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function. J Exp Med (2000) 5.79
Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo. J Exp Med (1998) 5.33
Hospital-acquired infection with vancomycin-resistant Enterococcus faecium transmitted by electronic thermometers. Ann Intern Med (1992) 4.81
Polymorphic secreted kinases are key virulence factors in toxoplasmosis. Science (2006) 4.23
The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection. J Exp Med (2000) 3.78
Immunogenicity of combined diphtheria, tetanus, and pertussis vaccine given at 2, 3, and 4 months versus 3, 5, and 9 months of age. Lancet (1992) 3.60
Cardiovascular risk factors in British children from towns with widely differing adult cardiovascular mortality. BMJ (1996) 3.14
Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor alpha-chain. Nature (1985) 3.08
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes. J Exp Med (1998) 3.04
Depressed mood and the incidence of Alzheimer's disease in the elderly living in the community. Arch Gen Psychiatry (1996) 2.99
The rhythm of the normal human heart. Lancet (1976) 2.94
Thiamin biosynthesis in prokaryotes. Arch Microbiol (1999) 2.91
Treatment of first episodes of genital herpes simplex virus infection with oral acyclovir. A randomized double-blind controlled trial in normal subjects. N Engl J Med (1983) 2.91
Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. Endoscopy (2007) 2.88
Sensitive system for visualising biotinylated DNA probes hybridised in situ: rapid sex determination of intact cells. J Clin Pathol (1985) 2.84
The Huntington's disease candidate region exhibits many different haplotypes. Nat Genet (1992) 2.84
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc Natl Acad Sci U S A (1995) 2.80
A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals. AIDS (1999) 2.75
Radiation Therapy Oncology Group (RTOG) 88-08 and Eastern Cooperative Oncology Group (ECOG) 4588: preliminary results of a phase III trial in regionally advanced, unresectable non-small-cell lung cancer. J Natl Cancer Inst (1995) 2.64
Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection. Gastroenterology (1999) 2.62
Angiogenesis inhibition and tumor regression caused by heparin or a heparin fragment in the presence of cortisone. Science (1983) 2.47
HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy. Proc Natl Acad Sci U S A (1999) 2.45
Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms. Hepatology (2000) 2.45
Protamine is an inhibitor of angiogenesis. Nature (1982) 2.30
Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J Immunol (1998) 2.24
Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood. Curr Biol (1998) 2.21
Oligoclonal expansions of CD8(+) T cells in chronic HIV infection are antigen specific. J Exp Med (1998) 2.13
Photosynthetic Carbon Fixation in Guard Cell Protoplasts of Vicia faba L. : Evidence from Radiolabel Experiments. Plant Physiol (1988) 2.12
Observer variation in the detection of colorectal neoplasia on double-contrast barium enema: implications for colorectal cancer screening and training. Clin Radiol (2003) 2.12
Twenty-four-hour intragastric pH patterns in ICU patients on ranitidine. Dig Dis Sci (1992) 2.04
A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer. Ann Oncol (2007) 2.03
Airway obstruction with percutaneous tracheostomy. Chest (1997) 2.02
Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy. Hepatology (2001) 1.99
High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: evidence for impaired CTL effector function. Eur J Immunol (2001) 1.99
Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells. Immunology (1997) 1.99
Groin hernia repair in Scotland. Br J Surg (2000) 1.93
Re-evaluating the treatment of nongonococcal urethritis: emphasizing emerging pathogens--a randomized clinical trial. Clin Infect Dis (2011) 1.92
Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection. AIDS (2000) 1.92
Identification of a diversity segment of human T-cell receptor beta-chain, and comparison with the analogous murine element. Nature (1984) 1.92
Spread of Mycobacterium tuberculosis in a community implementing recommended elements of tuberculosis control. JAMA (2000) 1.88
Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent. J Immunol (1999) 1.86
Health and exposures of United Kingdom Gulf war veterans. Part I: The pattern and extent of ill health. Occup Environ Med (2001) 1.84
The solitary thyroid nodule--benign or malignant. Praxis (1967) 1.81
Uterine contractions at the time of embryo transfer alter pregnancy rates after in-vitro fertilization. Hum Reprod (1998) 1.80
Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children. J Virol (2000) 1.79
Muscular contraction: kinetics of crossbridge attachment studied by high-frequency stiffness measurements. Science (1982) 1.71
Light chain 2 profile and activity of human ventricular myosin during dilated cardiomyopathy. Identification of a causal agent for impaired myocardial function. Circulation (1992) 1.70
Are there age and sex differences in the investigation and treatment of heart failure? A population-based study. Br J Gen Pract (2000) 1.67
Alpha-blocker therapy can be withdrawn in the majority of men following initial combination therapy with the dual 5alpha-reductase inhibitor dutasteride. Eur Urol (2003) 1.63
Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1. J Virol (1999) 1.63
Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac. Mol Cell Biol (1998) 1.63
Introducing care pathway commissioning to primary dental care: measuring performance. Br Dent J (2011) 1.61
Low back pain in schoolchildren: the role of mechanical and psychosocial factors. Arch Dis Child (2003) 1.61
Audit of the safety and effectiveness of ketamine for procedural sedation in the emergency department. Emerg Med J (2008) 1.60
Sperm DNA quality predicts intrauterine insemination outcome: a prospective cohort study. Hum Reprod (2002) 1.60
Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100. J Clin Invest (1998) 1.59
Identification of an immunodominant region of Fel d 1 and characterization of constituent epitopes. Clin Exp Allergy (2008) 1.59
Epidemiological studies of tooth wear and dental erosion in 14-year-old children in North West England. Part 1: The relationship with water fluoridation and social deprivation. Br Dent J (2004) 1.59
Human CD8+ CTL specific for the mycobacterial major secreted antigen 85A. J Immunol (2000) 1.58
Female patients with breast carcinoma age 30 years and younger have a poor prognosis: the M.D. Anderson Cancer Center experience. Cancer (2001) 1.57
Serum müllerian-inhibiting substance levels during normal menstrual cycles. Fertil Steril (2000) 1.56
Community-based heart health promotion: perceptions of facilitators and barriers. Can J Public Health (1999) 1.55
Psychological and pharmacological treatments of social phobia: a meta-analysis. J Clin Psychopharmacol (2001) 1.51
Local recurrence and survival among black women with early-stage breast cancer treated with breast-conservation therapy or mastectomy. Ann Surg Oncol (1999) 1.50
Diagnostic value of DNA analysis in effusions by flow cytometry and image analysis. A prospective study on 102 patients as compared with cytologic examination. Am J Clin Pathol (1991) 1.50
Thermal balloon ablation versus endometrial resection for the treatment of abnormal uterine bleeding. Hum Reprod (1999) 1.48
Manganese toxicity in a patient with cholestasis receiving total parenteral nutrition. Anaesthesia (1994) 1.47
Coliform Infection of the Urinary Tract. J Clin Pathol (1949) 1.46
Health and exposures of United Kingdom Gulf war veterans. Part II: The relation of health to exposure. Occup Environ Med (2001) 1.45
Update on nutrition and psoriasis. Int J Dermatol (1993) 1.43
The Pharmacy Diabetes Care Program: assessment of a community pharmacy diabetes service model in Australia. Diabet Med (2007) 1.43
Gender differences in dimensions of anxiety sensitivity. J Anxiety Disord (1997) 1.43
The histamine-synthesizing enzyme histidine decarboxylase is upregulated by keratinocytes in atopic skin. Br J Dermatol (2014) 1.42
Characterisation of zuclopenthixol metabolism by in vitro and therapeutic drug monitoring studies. Acta Psychiatr Scand (2010) 1.41
Impaired production of gamma-interferon by newborn cells in vitro is due to a functionally immature macrophage. J Immunol (1985) 1.40
Sneddon's syndrome with granulomatous leptomeningeal infiltration. Stroke (1995) 1.40
President's Address. Postgraduate, post-Todd. Specialist postgraduate medical education. Proc R Soc Med (1969) 1.39
Ultrasonographic anatomy of the equine temporomandibular joint. Equine Vet J (1999) 1.39
Fatal syndrome in lambs. Vet Rec (1994) 1.39
Improving visualization of distal and terminal ileum during the small bowel meal: an evaluation of fluoroscopic manoeuvres. Clin Radiol (1995) 1.39
A short history of the International Association of Endocrine Surgeons. World J Surg (1988) 1.38
Multifocal fibrosclerosis. Proc R Soc Med (1970) 1.38
Measurement of two- and three-nucleon short-range correlation probabilities in nuclei. Phys Rev Lett (2006) 1.37
Genetic discrimination: international perspectives. Annu Rev Genomics Hum Genet (2012) 1.35
Stiffness and force in activated frog skeletal muscle fibers. Biophys J (1986) 1.34
A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition. J Neural Transm (Vienna) (2003) 1.33
The enzymology of sulfur activation during thiamin and biotin biosynthesis. Curr Opin Chem Biol (1999) 1.33
Human cardiac beta-adrenergic receptors: subtype heterogeneity delineated by direct radioligand binding. Life Sci (1983) 1.32
Immunogenicities of intravenous and intramuscular administrations of modified vaccinia virus Ankara-based multi-CTL epitope vaccine for human immunodeficiency virus type 1 in mice. J Gen Virol (1998) 1.32
Segmentation, not rhyming, predicts early progress in learning to read. J Exp Child Psychol (1998) 1.31
Primary structures of the catalytic subunits from two molecular forms of acetylcholinesterase. A comparison of NH2-terminal and active center sequences. J Biol Chem (1985) 1.29
Clinic-based intervention to promote literacy. A pilot study. Am J Dis Child (1991) 1.29
Cutting edge: rapid cloning of tumor-specific CTL suitable for adoptive immunotherapy of melanoma. J Immunol (1999) 1.28
Identification of individual amino acids required for secretion within the haemolysin (HlyA) C-terminal targeting region. Mol Microbiol (1992) 1.27
Cathepsin B2 measurement by sensitive fluorometric ammonia analysis. Anal Biochem (1974) 1.26
Labor pain is reduced by massage therapy. J Psychosom Obstet Gynaecol (1997) 1.25
A normative study of the maintenance of wakefulness test (MWT). Electroencephalogr Clin Neurophysiol (1997) 1.25