Noncardiac chest pain: epidemiology, natural course and pathogenesis.

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Published in J Neurogastroenterol Motil on April 27, 2011

Authors

Ronnie Fass1, Sami R Achem

Author Affiliations

1: Section of Gastroenterology, Department of Medicine, Southern Arizona VA Health Care System, Tucson, Arizona, USA. Ronnie.Fass@va.gov

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Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology (1997) 8.51

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The clinical and economic value of a short course of omeprazole in patients with noncardiac chest pain. Gastroenterology (1998) 3.60

Anxiety and depression in patients with chest pain referred for exercise testing. Lancet (1985) 2.85

Unexplained chest pain in patients with normal coronary arteriograms: a follow-up study of functional status. N Engl J Med (1980) 2.33

Prevalence, clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population: a population-based study. Aliment Pharmacol Ther (2003) 2.30

Chest pain associated with nutcracker esophagus: a preliminary study of the role of gastroesophageal reflux. Am J Gastroenterol (1993) 2.28

Contribution of central sensitisation to the development of non-cardiac chest pain. Lancet (2000) 2.21

Chest pain: panic attack or heart attack? Int J Clin Pract (2000) 2.08

Esophageal testing of patients with noncardiac chest pain or dysphagia. Results of three years' experience with 1161 patients. Ann Intern Med (1987) 2.02

How effective are rapid access chest pain clinics? Prognosis of incident angina and non-cardiac chest pain in 8762 consecutive patients. Heart (2006) 1.98

Abnormal sensory perception in patients with esophageal chest pain. Gastroenterology (1986) 1.87

Esophageal chest pain: current controversies in pathogenesis, diagnosis, and therapy. Ann Intern Med (1989) 1.84

Non-cardiac chest pain: prevalence, risk factors, impact and consulting--a population-based study. Aliment Pharmacol Ther (2003) 1.84

Sensitivity of the esophageal mucosa to pH in gastroesophageal reflux disease. Gastroenterology (1989) 1.74

Esophageal function in patients with angina-type chest pain and normal coronary angiograms. Ann Surg (1982) 1.71

Prevalence of increased esophageal muscle thickness in patients with esophageal symptoms. Am J Gastroenterol (2007) 1.71

Psychiatric illness and contraction abnormalities of the esophagus. N Engl J Med (1983) 1.70

Differential effect of long-term esophageal acid exposure on mechanosensitivity and chemosensitivity in humans. Gastroenterology (1998) 1.70

Psychological morbidity and illness appraisals of patients with cardiac and non-cardiac chest pain attending a rapid access chest pain clinic: a longitudinal cohort study. Heart (2007) 1.69

Sustained esophageal contraction: a marker of esophageal chest pain identified by intraluminal ultrasonography. Gastroenterology (1999) 1.67

Non-cardiac chest pain: squeezing the life out of the Australian healthcare system? Med J Aust (2000) 1.63

Short course of omeprazole: a better first diagnostic approach to noncardiac chest pain than endoscopy, manometry, or 24-hour esophageal pH monitoring. J Clin Gastroenterol (2002) 1.58

Clinical value of esophageal motility testing. Dig Dis (1998) 1.51

Panic disorder in emergency department chest pain patients: prevalence, comorbidity, suicidal ideation, and physician recognition. Am J Med (1996) 1.49

Investigation of esophageal sensation and biomechanical properties in functional chest pain. Neurogastroenterol Motil (2010) 1.44

Psychological morbidity in patients with chest pain and normal or near-normal coronary arteries: a long-term follow-up study. Psychol Med (1995) 1.44

Spontaneous noncardiac chest pain. Evaluation by 24-hour ambulatory esophageal motility and pH monitoring. Gastroenterology (1988) 1.38

Prevalence, clinical spectrum and atypical symptoms of gastro-oesophageal reflux in Argentina: a nationwide population-based study. Aliment Pharmacol Ther (2005) 1.32

Noncardiac chest pain: epidemiology, natural history, health care seeking, and quality of life. Gastroenterol Clin North Am (2004) 1.29

Prevalence of upper gastrointestinal tract findings in patients with noncardiac chest pain versus those with gastroesophageal reflux disease (GERD)-related symptoms: results from a national endoscopic database. Am J Gastroenterol (2007) 1.22

Population based study of noncardiac chest pain in southern Chinese: prevalence, psychosocial factors and health care utilization. World J Gastroenterol (2004) 1.22

Abnormal GERD parameters on ambulatory pH monitoring predict therapeutic success in noncardiac chest pain. Am J Gastroenterol (2009) 1.21

Sustained esophageal contraction: a motor correlate of heartburn symptom. Am J Physiol Gastrointest Liver Physiol (2001) 1.19

Patients with angina with normal and near normal coronary arteries: clinical and psychosocial state 12 months after angiography. Br Med J (Clin Res Ed) (1983) 1.16

Analysis of 24-hour esophageal pressure and pH data in unselected patients with noncardiac chest pain. Gastroenterology (1990) 1.15

Predicting panic disorder among patients with chest pain: an analysis of the literature. Psychosomatics (2003) 1.15

Non-cardiac chest pain: predictors of health care seeking, the types of health care professional consulted, work absenteeism and interruption of daily activities. Aliment Pharmacol Ther (2004) 1.13

Chest pain: relationship of psychiatric illness to coronary arteriographic results. Am J Med (1988) 1.11

Pathophysiology of chest pain in patients with nutcracker esophagus. Am J Gastroenterol (2001) 1.10

Non-cardiac chest pain and benign palpitations in the cardiac clinic. Br Heart J (1994) 1.08

Esophageal visceral pain sensitivity: effects of TENS and correlation with manometric findings. Dig Dis Sci (1998) 1.08

Atypical or nonanginal chest pain. Panic disorder or coronary artery disease? Arch Intern Med (1987) 1.08

Unimproved chest pain in patients with minimal or no coronary disease: a behavioral phenomenon. Am Heart J (1984) 1.06

Chest pain and gastroesophageal reflux disease. J Clin Gastroenterol (2000) 1.06

Graded esophageal balloon distention. A new provocative test for noncardiac chest pain. Dig Dis Sci (1986) 1.04

Natural history and predictors of outcome for non-cardiac chest pain: a prospective 4-year cohort study. Neurogastroenterol Motil (2008) 1.04

Chest pain with normal coronary arteries: a comparative study of psychiatric and social morbidity. Psychol Med (1984) 1.04

Gastroesophageal reflux disease in noncardiac chest pain. Gastroenterol Clin North Am (2004) 1.04

The clinical spectrum of coronary artery disease and its surgical and medical management, 1974-1979. The Coronary Artery Surgery study. Circulation (1982) 1.03

A long-term follow-up study of patients with ischaemic heart disease versus patients with nonspecific chest pain. J Psychosom Res (1995) 1.02

Psychosocial factors in patients with noncardiac chest pain. Psychosom Med (2003) 1.01

Non-cardiac chest pain: a retrospective cohort study of patients who attended a Rapid Access Chest Pain Clinic. Fam Pract (2007) 1.01

"Nonspecific" chest pain associated with high long-term mortality: results from the primary prevention study in Göteborg, Sweden. Clin Cardiol (1998) 1.00

One-year psychosocial follow-up of patients with chest pain and angiographically normal coronary arteries. Am J Cardiol (1988) 0.99

Acute noncardiac chest pain in a coronary care unit. Evaluation by 24-hour pressure and pH recording of the esophagus. Gastroenterology (1992) 0.99

Functional chest pain: esophageal or overlapping functional disorder. J Clin Gastroenterol (2007) 0.99

Chest pain as a consequence of abnormal visceral nociception. Dig Dis Sci (1993) 0.98

Abnormal cerebral processing of oesophageal stimuli in patients with noncardiac chest pain (NCCP). Neurogastroenterol Motil (2000) 0.97

Prospective study on prevalence of esophageal chest pain in patients referred on an elective basis to a cardiac unit for suspected myocardial ischemia. Dig Dis Sci (1991) 0.97

Nausea and vomiting during acute myocardial infarction and its relation to infarct size and location. Am J Cardiol (1987) 0.96

The contribution of gastroesophageal reflux to chest pain in patients with coronary artery disease. Ann Intern Med (1992) 0.95

Noncardiac chest pain. J Clin Gastroenterol (2008) 0.95

Utility of upper endoscopy in the evaluation of noncardiac chest pain. Gastrointest Endosc (1991) 0.94

Prevalence and recognition of panic states in STARNET patients presenting with chest pain. J Fam Pract (1997) 0.94

Long-term follow-up of symptomatic status of patients with noncardiac chest pain: is diagnosis of esophageal etiology helpful? Am J Gastroenterol (1987) 0.93

Prior sensitization of esophageal mucosa by acid reflux predisposes to reflux-induced chest pain. J Clin Gastroenterol (2000) 0.92

Non-cardiac chest pain: the long-term natural history and comparison with gastroesophageal reflux disease. Am J Gastroenterol (2009) 0.92

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The effect of an empirical trial of high-dose lansoprazole on symptom response of patients with non-cardiac chest pain--a randomized, double-blind, placebo-controlled, crossover trial. Aliment Pharmacol Ther (2004) 0.92

Evaluation of noncardiac chest pain: diagnostic approach, coping strategies and quality of life. Eur J Pain (2006) 0.92

Functional chest pain of esophageal origin: hyperalgesia or motor dysfunction. Am J Gastroenterol (2001) 0.91

Role of clinical presentation in diagnosing reflux-related non-cardiac chest pain. J Gastroenterol Hepatol (2007) 0.91

Panic disorder in cardiac outpatients. Am J Psychiatry (1993) 0.91

Intraesophageal acid perfusion sensitizes the esophagus to mechanical distension: a Barostat study. Am J Gastroenterol (2000) 0.91

Sensitization to painful distention and abnormal sensory perception in the esophagus. Gastroenterology (1995) 0.91

Assessment of oesophageal motor function in patients with dysphagia or chest pain - the Clinical Outcomes Research Initiative experience. Aliment Pharmacol Ther (2003) 0.90

Anxiety and depressive disorders in patients presenting with chest pain to the emergency department: a comparison between cardiac and non-cardiac origin. J Emerg Med (2008) 0.90

Chest pain with negative cardiac diagnostic studies. Relationship to psychiatric illness. J Nerv Ment Dis (1988) 0.89

Clinical profile and long-term prognosis of women < or = 50 years of age referred for coronary angiography for evaluation of chest pain. Am J Cardiol (2000) 0.89

Upper endoscopy in patients with angina and normal coronary angiograms. Endoscopy (1995) 0.89

The effect of a therapeutic trial of high-dose rabeprazole on symptom response of patients with non-cardiac chest pain: a randomized, double-blind, placebo-controlled, crossover trial. Aliment Pharmacol Ther (2005) 0.89

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Psychological symptom profiles in patients with chest pain. J Psychosom Res (1994) 0.89

Anxiety disorder in patients with non-specific chest pain in the emergency setting. Emerg Med J (2006) 0.87

Prognosis, severity of symptoms, and aspects of well-being among patients in whom myocardial infarction was ruled out. Clin Cardiol (1994) 0.87

Psychosocial and developmental antecedents of chest pain in young adults. Psychosom Med (2000) 0.86

Influence of the normal personality dimension of neuroticism on chest pain symptoms and coronary artery disease. Am J Cardiol (1987) 0.85

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Chest pain without established ischaemic heart disease in primary care patients: associated comorbidities and mortality. Br J Gen Pract (2009) 0.84

Symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy-negative patients with non-cardiac chest pain. Aliment Pharmacol Ther (2003) 0.84

Mental disorders in patients with noncardiac chest pain. Acta Psychiatr Scand (1994) 0.84

Attitudes and referral patterns of primary care physicians when evaluating subjects with noncardiac chest pain--a national survey. Dig Dis Sci (2005) 0.83

Different psychological profiles in non-cardiac chest pain and coronary artery disease: a controlled study. Rev Esp Cardiol (2010) 0.83

Personality profiles in patients referred for chest pain. Investigation with emphasis on panic disorder patients. Psychosomatics (2000) 0.83

[Esophageal manometry in patients with non cardiac chest pain]. Rev Med Chil (2006) 0.82

Diagnosis and treatment of patients with gastroesophageal reflux and noncardiac chest pain. South Med J (1994) 0.82

Predictors of mortality and morbidity following admission with chest pain. J R Coll Physicians Lond (1997) 0.81

Psychological factors, pain attribution and medical morbidity in chest-pain patients with and without coronary artery disease. Gen Hosp Psychiatry (2004) 0.81

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