Published in Biophys J on April 01, 1990
A structural model of the tetrodotoxin and saxitoxin binding site of the Na+ channel. Biophys J (1994) 2.64
A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification. Proc Natl Acad Sci U S A (2003) 1.99
Divalent cation selectivity for external block of voltage-dependent Na+ channels prolonged by batrachotoxin. Zn2+ induces discrete substates in cardiac Na+ channels. J Gen Physiol (1991) 1.66
Tests of continuum theories as models of ion channels. I. Poisson-Boltzmann theory versus Brownian dynamics. Biophys J (2000) 1.51
Permeant ion effects on the gating kinetics of the type L potassium channel in mouse lymphocytes. J Gen Physiol (1991) 1.34
Competitive binding interaction between Zn2+ and saxitoxin in cardiac Na+ channels. Evidence for a sulfhydryl group in the Zn2+/saxitoxin binding site. Biophys J (1991) 1.33
Surface charge and calcium channel saturation in bullfrog sympathetic neurons. J Gen Physiol (1995) 1.31
Divalent cation competition with [3H]saxitoxin binding to tetrodotoxin-resistant and -sensitive sodium channels. A two-site structural model of ion/toxin interaction. J Gen Physiol (1993) 1.23
Modeling ion permeation through batrachotoxin-modified Na+ channels from rat skeletal muscle with a multi-ion pore. Biophys J (1992) 1.22
Role of outer ring carboxylates of the rat skeletal muscle sodium channel pore in proton block. J Physiol (2002) 1.12
Ion conduction in substates of the batrachotoxin-modified Na+ channel from toad skeletal muscle. Biophys J (1993) 1.11
Selectivity and permeation in calcium release channel of cardiac muscle: alkali metal ions. Biophys J (1999) 1.09
CFTR: a cysteine at position 338 in TM6 senses a positive electrostatic potential in the pore. Biophys J (2004) 1.08
Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block. J Gen Physiol (2008) 1.08
On the nature of antimicrobial activity: a model for protegrin-1 pores. J Am Chem Soc (2008) 1.07
Extracellular divalent and trivalent cation effects on sodium current kinetics in single canine cardiac Purkinje cells. J Physiol (1992) 1.07
Differential effects of sulfhydryl reagents on saxitoxin and tetrodotoxin block of voltage-dependent Na channels. Biophys J (1994) 1.07
Ion permeation, divalent ion block, and chemical modification of single sodium channels. Description by single- and double-occupancy rate-theory models. J Gen Physiol (1994) 1.06
Permeation of Na+ through open and Zn(2+)-occupied conductance states of cardiac sodium channels modified by batrachotoxin: exploring ion-ion interactions in a multi-ion channel. Biophys J (1994) 1.00
Intra and extracellular surface charges near Ca2+ channels in neurons and neuroblastoma cells. Biophys J (1992) 0.98
The influence of surface charges on the conductance of the human connexin37 gap junction channel. Biophys J (2000) 0.95
On the interaction of bovine pancreatic trypsin inhibitor with maxi Ca(2+)-activated K+ channels. A model system for analysis of peptide-induced subconductance states. J Gen Physiol (1991) 0.94
Conduction through the inward rectifier potassium channel, Kir2.1, is increased by negatively charged extracellular residues. J Gen Physiol (2005) 0.94
Lipid surface charge does not influence conductance or calcium block of single sodium channels in planar bilayers. Biophys J (1992) 0.93
Isoform-dependent interaction of voltage-gated sodium channels with protons. J Physiol (2006) 0.90
A simple model for surface charge on ion channel proteins. Biophys J (1994) 0.86
SAP97 regulates Kir2.3 channels by multiple mechanisms. Am J Physiol Heart Circ Physiol (2009) 0.86
Profiles of permeation through Na-channels. Biophys J (1993) 0.81
Mechanisms of cation permeation in cardiac sodium channel: description by dynamic pore model. Biophys J (1999) 0.80
Trimethyloxonium modification of batrachotoxin-activated Na channels alters functionally important protein residues. Biophys J (1995) 0.76
Surface potentials and the calculated selectivity of ion channels. Biophys J (2002) 0.76
Ion conductance of the Ca(2+)-activated maxi-K+ channel from the embryonic rat brain. Biophys J (1997) 0.76
Permeation models and structure-function relationships in ion channels. J Biol Phys (2002) 0.75
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Mechanism of ion permeation through calcium channels. Nature (1984) 9.82
The electrostatic properties of membranes. Annu Rev Biophys Biophys Chem (1989) 5.37
Ionic selectivity, saturation, and block in sodium channels. A four-barrier model. J Gen Physiol (1975) 5.31
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Electrostatic calculations for an ion channel. I. Energy and potential profiles and interactions between ions. Biophys J (1978) 4.65
Ion-channel entrances influence permeation. Net charge, size, shape, and binding considerations. Biophys J (1986) 3.19
Electrostatic modeling of ion pores. Energy barriers and electric field profiles. Biophys J (1982) 3.01
Structure and function of an acetylcholine receptor. Biophys J (1982) 2.92
Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block. J Gen Physiol (1987) 2.55
Sodium channel permeation in squid axons. II: Non-independence and current-voltage relations. J Physiol (1980) 2.10
How electrolyte shielding influences the electrical potential in transmembrane ion channels. Biophys J (1989) 1.97
Electrostatic modeling of ion pores. II. Effects attributable to the membrane dipole potential. Biophys J (1983) 1.91
How pore mouth charge distributions alter the permeability of transmembrane ionic channels. Biophys J (1987) 1.87
Batrachotoxin-modified sodium channels in planar lipid bilayers. Characterization of saxitoxin- and tetrodotoxin-induced channel closures. J Gen Physiol (1987) 1.57
Symmetry and asymmetry of permeation through toxin-modified Na+ channels. Biophys J (1988) 1.20
Effect of pore structure on energy barriers and applied voltage profiles. I. Symmetrical channels. Biophys J (1984) 1.18
Molecular properties of ion permeation through sodium channels. Annu Rev Biophys Biophys Chem (1987) 1.18
Interactions of permeant cations with sodium channels of squid axon membranes. Biophys J (1985) 1.08
Influence of negative surface charge on toxin binding to canine heart Na channels in planar bilayers. Biophys J (1989) 1.04
Dimethonium, a divalent cation that exerts only a screening effect on the electrostatic potential adjacent to negatively charged phospholipid bilayer membranes. J Membr Biol (1983) 1.02
Electrostatic modeling of ion pores. Energy barriers and electric field profiles. Biophys J (1982) 3.01
Electrostatic modeling of ion pores. II. Effects attributable to the membrane dipole potential. Biophys J (1983) 1.91
Energy barriers for passage of ions through channels. Exact solution of two electrostatic problems. Biophys Chem (1981) 1.90
How pore mouth charge distributions alter the permeability of transmembrane ionic channels. Biophys J (1987) 1.87
Relaxation studies of ion transport systems in lipid bilayer membranes. Q Rev Biophys (1981) 1.81
Molecular dynamics simulation of cation motion in water-filled gramicidinlike pores. Biophys J (1984) 1.73
Theoretical perspectives on ion-channel electrostatics: continuum and microscopic approaches. Q Rev Biophys (1992) 1.40
A semi-microscopic Monte Carlo study of permeation energetics in a gramicidin-like channel: the origin of cation selectivity. Biophys J (1996) 1.38
Why is gramicidin valence selective? A theoretical study. Biophys J (1987) 1.37
Effect of pore structure on energy barriers and applied voltage profiles. I. Symmetrical channels. Biophys J (1984) 1.18
Extended dipolar chain model for ion channels: electrostriction effects and the translocational energy barrier. Biophys J (1995) 1.04
Influence of a channel-forming peptide on energy barriers to ion permeation, viewed from a continuum dielectric perspective. Biophys J (1994) 0.97
Ion-water and water-water interactions in a gramicidinlike channel: effects due to group polarizability and backbone flexibility. Biophys Chem (1997) 0.97
Effect of pore structure on energy barriers and applied voltage profiles. II. Unsymmetrical channels. Biophys J (1984) 0.96
Modeling permeation energetics in the KcsA potassium channel. Biophys J (2003) 0.95
Ion permeation and chemical kinetics. J Gen Physiol (1999) 0.86
Electrostatic modeling of ion pores. Multipolar sources. Biophys Chem (1987) 0.86
A laser-temperature-jump method for the study of the rate of transfer of hydrophobic ions and carriers across the interface of thin lipid membranes. Biophys Chem (1981) 0.86
The interaction of Cl- with a gramicidin-like channel. Biophys Chem (1987) 0.85
Ionic interactions in multiply occupied channels. Novartis Found Symp (1999) 0.82
Electrostatic models of the gramicidin and the delayed rectifier potassium channel. Biophys J (1984) 0.81
The channel properties of possible gramicidin dimers. J Theor Biol (1989) 0.79
Theoretical study of the antiparallel double-stranded helical dimer of gramicidin as an ion channel. Biophys J (1988) 0.77
How shortening a channel may lower its conductance. The case of des-Val7-DVal8-gramicidin A. Biochim Biophys Acta (1985) 0.75