Published in Hum Mutat on June 01, 2011
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Single nucleotide polymorphism in toll-like receptor 6 is associated with a decreased risk for ureaplasma respiratory tract colonization and bronchopulmonary dysplasia in preterm infants. Pediatr Infect Dis J (2013) 0.86
Association of Toll-like receptor polymorphisms with HIV status in North Americans. Genes Immun (2014) 0.80
Adaptive Evolution of Toll-Like Receptors (TLRs) in the Family Suidae. PLoS One (2015) 0.75
Whole genome sequencing of an African American family highlights toll like receptor 6 variants in Kawasaki disease susceptibility. PLoS One (2017) 0.75
TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients. Oncotarget (2016) 0.75
Identification of sequence variants influencing immunoglobulin levels. Nat Genet (2017) 0.75
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat Genet (2003) 15.31
Natural selection has driven population differentiation in modern humans. Nat Genet (2008) 7.48
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Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways. Hum Mol Genet (2007) 2.55
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. PLoS Genet (2009) 2.35
Integration of genetic and immunological insights into a model of celiac disease pathogenesis. Annu Rev Immunol (2011) 2.31
From social to genetic structures in central Asia. Curr Biol (2007) 2.09
The fingerprint of phantom mutations in mitochondrial DNA data. Am J Hum Genet (2002) 2.07
Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set. PLoS Genet (2009) 2.07
Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers. Proc Natl Acad Sci U S A (2008) 1.96
The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression. EMBO J (2003) 1.75
Social environment is associated with gene regulatory variation in the rhesus macaque immune system. Proc Natl Acad Sci U S A (2012) 1.63
USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response. PLoS One (2011) 1.60
A single-nucleotide polymorphism in the human beta-defensin 1 gene is associated with HIV-1 infection in Italian children. AIDS (2004) 1.59
Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions. PLoS One (2010) 1.55
Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis. PLoS Med (2006) 1.42
Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis. J Immunol (2002) 1.42
TYK2 activity promotes ligand-induced IFNAR1 proteolysis. Biochem J (2006) 1.39
Strong maternal Khoisan contribution to the South African coloured population: a case of gender-biased admixture. Am J Hum Genet (2010) 1.37
Evolutionary genetic dissection of human interferons. J Exp Med (2011) 1.32
Human interleukin-19 and its receptor: a potential role in the induction of Th2 responses. Int Immunopharmacol (2004) 1.32
Y-chromosome analysis in Egypt suggests a genetic regional continuity in Northeastern Africa. Hum Biol (2002) 1.31
The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region. Am J Hum Genet (2005) 1.28
Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disorders. Am J Med Genet B Neuropsychiatr Genet (2006) 1.24
Evolutionary trajectories of primate genes involved in HIV pathogenesis. Mol Biol Evol (2009) 1.23
Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes. Am J Hum Genet (2006) 1.23
Receptor density is key to the alpha2/beta interferon differential activities. Mol Cell Biol (2009) 1.22
Ligand-independent pathway that controls stability of interferon alpha receptor. Biochem Biophys Res Commun (2007) 1.21
A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity. Proc Natl Acad Sci U S A (2003) 1.19
Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages. Infect Immun (2006) 1.19
Signatures of purifying and local positive selection in human miRNAs. Am J Hum Genet (2009) 1.18
Down-modulation of responses to type I IFN upon T cell activation. J Immunol (2003) 1.17
Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2. Biochem J (2007) 1.14
Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation. Blood (2006) 1.13
A dual role of IFN-alpha in the balance between proliferation and death of human CD4+ T lymphocytes during primary response. J Immunol (2004) 1.11
NF-{kappa}B is required for STAT-4 expression during dendritic cell maturation. J Leukoc Biol (2006) 1.11
Evolutionary insights into the high worldwide prevalence of MBL2 deficiency alleles. Hum Mol Genet (2006) 1.09
USP18 establishes the transcriptional and anti-proliferative interferon α/β differential. Biochem J (2012) 1.09
Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region. Am J Hum Genet (2013) 1.06
Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene. Hum Mutat (2006) 1.04
Human IL-19 regulates immunity through auto-induction of IL-19 and production of IL-10. Eur J Immunol (2005) 1.04
Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression. J Leukoc Biol (2006) 1.03
Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia. Eur J Hum Genet (2007) 1.01
Effects of positively selected sequence variations in human and Macaca fascicularis beta-defensins 2 on antimicrobial activity. Antimicrob Agents Chemother (2004) 0.99
Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif. J Biol Chem (2008) 0.99
Beta-defensin 1 gene variability among non-human primates. Immunogenetics (2002) 0.98
Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity. Cell Metab (2012) 0.97
The genetic or mythical ancestry of descent groups: lessons from the Y chromosome. Am J Hum Genet (2004) 0.97
IL-18 gene promoter polymorphism is involved in HIV-1 infection in a Brazilian pediatric population. Immunogenetics (2006) 0.97
DEFB-1 genetic polymorphism screening in HIV-1 positive pregnant women and their children. J Matern Fetal Neonatal Med (2006) 0.94
Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis. PLoS One (2012) 0.92
MBL2 polymorphisms screening in a regional Italian CF Center. J Cyst Fibros (2005) 0.92
Inhibition of beta-defensin gene expression in airway epithelial cells by low doses of residual oil fly ash is mediated by vanadium. Toxicol Sci (2006) 0.91
Evolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation. Mol Biol Evol (2011) 0.90
Not all tetramer binding CD8+ T cells can produce cytokines and chemokines involved in the effector functions of virus-specific CD8+ T lymphocytes in HIV-1 infected children. J Clin Immunol (2005) 0.90
A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection. Genome Res (2014) 0.90
Contemporary paternal genetic landscape of Polish and German populations: from early medieval Slavic expansion to post-World War II resettlements. Eur J Hum Genet (2012) 0.90
The evolutionary landscape of cytosolic microbial sensors in humans. Am J Hum Genet (2012) 0.88
Length variation of DC-SIGN and L-SIGN neck-region has no impact on tuberculosis susceptibility. Hum Immunol (2006) 0.88
T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells. PLoS One (2010) 0.88
The Human Y Chromosome: The Biological Role of a "Functional Wasteland" J Biomed Biotechnol (2001) 0.88
Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations. Hum Mol Genet (2013) 0.88
Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules. J Biol Chem (2004) 0.87
Primate beta-defensins--structure, function and evolution. Curr Protein Pept Sci (2005) 0.87
DC-SIGNR neck-region polymorphisms and HIV-1 susceptibility: From population stratification to a possible advantage of the 7/5 heterozygous genotype. J Infect Dis (2006) 0.85
Jakmip1 is expressed upon T cell differentiation and has an inhibitory function in cytotoxic T lymphocytes. J Immunol (2008) 0.85
DC-SIGN interacts with Mycobacterium leprae but sequence variation in this lectin is not associated with leprosy in the Pakistani population. Hum Immunol (2006) 0.85
Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3. J Biol Chem (2012) 0.84
Towards a crucial role for DC-SIGN in tuberculosis and beyond. Trends Microbiol (2006) 0.84
Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients. Hum Immunol (2007) 0.84
Two rare disease-associated Tyk2 variants are catalytically impaired but signaling competent. J Immunol (2013) 0.84
Genetic traces of east-to-west human expansion waves in Eurasia. Am J Phys Anthropol (2008) 0.82
Prognostic value of the stromal cell-derived factor 1 3'A mutation in pediatric human immunodeficiency virus type 1 infection. J Infect Dis (2002) 0.82
MBL2 polymorphisms are involved in HIV-1 infection in Brazilian perinatally infected children. AIDS (2003) 0.82
Induction of regulatory T cells by a murine β-defensin. J Immunol (2011) 0.81
Demeter's legacy: rapid changes to our genome imposed by diet. Trends Ecol Evol (2008) 0.81
Phylogenetic relationships among the Lorisoidea as indicated by craniodental morphology and mitochondrial sequence data. Am J Primatol (2007) 0.80
Biochemical monitoring of the early endocytic traffic of the type I interferon receptor. J Interferon Cytokine Res (2010) 0.80
Protective role of DC-SIGN (CD209) neck-region alleles with <5 repeat units in HIV-1 transmission. J Infect Dis (2008) 0.80
The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor. J Biol Chem (2008) 0.79
The role played by natural selection on Mendelian traits in humans. Ann N Y Acad Sci (2010) 0.79
Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes. Immunol Lett (2010) 0.79
Evolutionary genetics evidence of an essential, nonredundant role of the IFN-γ pathway in protective immunity. Hum Mutat (2011) 0.78
Don't move: LRRK2 arrests NFAT in the cytoplasm. Nat Immunol (2011) 0.78
Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor. Int J Mol Med (2012) 0.78
The Tyr978X BRCA1 mutation: occurrence in non-Jewish Iranians and haplotype in French-Canadian and non-Ashkenazi Jews. Fam Cancer (2005) 0.78
Type I interferon potentiates T-cell receptor mediated induction of IL-10-producing CD4⁺ T cells. Eur J Immunol (2013) 0.77
Molecular epidemiology of the HHV-8 K1 gene from Moroccan patients with Kaposi's sarcoma. Virology (2006) 0.77
Italian multicentric pilot study on MBL2 genetic polymorphisms in HIV positive pregnant women and their children. J Matern Fetal Neonatal Med (2005) 0.76
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