Published in Acta Crystallogr D Biol Crystallogr on May 17, 2011
FKBPs and the Akt/mTOR pathway. Cell Cycle (2013) 0.82
Structural basis of conformational transitions in the active site and 80's loop in the FK506-binding protein FKBP12. Biochem J (2014) 0.80
Crystal structure of the FK506 binding domain of human FKBP25 in complex with FK506. Protein Sci (2016) 0.79
Roles of Prolyl Isomerases in RNA-Mediated Gene Expression. Biomolecules (2015) 0.78
Differential conformational dynamics in the closely homologous FK506-binding domains of FKBP51 and FKBP52. Biochem J (2014) 0.78
Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6. Acta Crystallogr D Biol Crystallogr (2014) 0.77
Statistical allosteric coupling to the active site indole ring flip equilibria in the FK506-binding domain. Biophys Chem (2014) 0.77
Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins. J Biol Chem (2015) 0.75
Accelerated flexible protein-ligand docking using Hamiltonian replica exchange with a repulsive biasing potential. PLoS One (2017) 0.75
Structural basis for gluten intolerance in celiac sprue. Science (2002) 8.16
A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell (2005) 4.41
Integrative analysis of the mitochondrial proteome in yeast. PLoS Biol (2004) 2.31
Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett (2005) 1.59
Tim50, a novel component of the TIM23 preprotein translocase of mitochondria. EMBO J (2003) 1.46
FK506 binding protein 5 shapes stress responsiveness: modulation of neuroendocrine reactivity and coping behavior. Biol Psychiatry (2011) 1.37
The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress. Neuropharmacology (2011) 1.15
Structural and functional roles of the conserved cysteine residues of the redox-regulated import receptor Mia40 in the intermembrane space of mitochondria. J Biol Chem (2008) 1.13
Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes. Mol Biol Cell (2003) 1.02
Large FK506-binding proteins shape the pharmacology of rapamycin. Mol Cell Biol (2013) 0.98
The prospect of FKBP51 as a drug target. ChemMedChem (2012) 0.90
Fluorescent probes to characterise FK506-binding proteins. Chembiochem (2009) 0.89
XAP2 inhibits glucocorticoid receptor activity in mammalian cells. FEBS Lett (2009) 0.89
InterAKTions with FKBPs--mutational and pharmacological exploration. PLoS One (2013) 0.87
Corticotropin releasing factor receptor antagonists for major depressive disorder. Expert Opin Investig Drugs (2011) 0.84
Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J Med Chem (2013) 0.83
Loratadine and analogues: discovery and preliminary structure-activity relationship of inhibitors of the amino acid transporter B(0)AT2. J Med Chem (2014) 0.83
Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52. J Med Chem (2012) 0.82
Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52. J Med Chem (2012) 0.82
FKBPs and the Akt/mTOR pathway. Cell Cycle (2013) 0.82
Crystal structures of the free and ligand-bound FK1-FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge. J Mol Biol (2013) 0.81
Selective targeting of disease-relevant protein binding domains by O-phosphorylated natural product derivatives. ACS Chem Biol (2011) 0.79
Biomimetic screening of class-B G protein-coupled receptors. J Am Chem Soc (2011) 0.79
Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice. Psychoneuroendocrinology (2012) 0.78
Deficiency of FK506-binding protein (FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice. J Sleep Res (2013) 0.78
Snapshot of antidepressants at work: the structure of neurotransmitter transporter proteins. Angew Chem Int Ed Engl (2014) 0.78
A polymorphism in the Crhr1 gene determines stress vulnerability in male mice. Endocrinology (2014) 0.77
Functional coding variants in SLC6A15, a possible risk gene for major depression. PLoS One (2013) 0.77
Searching for the most effective screening system to identify cell-active inhibitors of beta-secretase. Biol Chem (2004) 0.76
Structural biology: Snapshot of an activated peptide receptor. Nature (2012) 0.75
Internal 32P-labeling of L-deoxyoligonucleotides. Nucleic Acids Res (2003) 0.75
Stereoselective construction of the 5-hydroxy diazabicyclo[4.3.1]decane-2-one scaffold, a privileged motif for FK506-binding proteins. Org Lett (2014) 0.75
Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs). Angew Chem Int Ed Engl (2014) 0.75