Published in Neuropsychopharmacology on June 08, 2011
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci (2012) 4.71
Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD. Front Psychiatry (2013) 1.22
Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5. Biochem Biophys Res Commun (2012) 1.12
FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. Genes Brain Behav (2012) 1.08
Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults. Psychopharmacology (Berl) (2012) 1.06
Genetic determinants of depression: recent findings and future directions. Harv Rev Psychiatry (2015) 1.02
Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner. Psychoneuroendocrinology (2012) 0.99
The biological effects of childhood trauma. Child Adolesc Psychiatr Clin N Am (2014) 0.99
DNA methylation and childhood maltreatment: from animal models to human studies. Neuroscience (2013) 0.98
Cannabinoid receptor genotype moderation of the effects of childhood physical abuse on anhedonia and depression. Arch Gen Psychiatry (2012) 0.97
The Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety Disorders. Neuropsychopharmacology (2015) 0.96
The role of hypothalamus-pituitary-adrenal genes and childhood trauma in borderline personality disorder. Eur Arch Psychiatry Clin Neurosci (2015) 0.94
Prevalence of bullying victimisation amongst first-episode psychosis patients and unaffected controls. Schizophr Res (2013) 0.88
Drug addiction and stress-response genetic variability: association study in African Americans. Ann Hum Genet (2014) 0.87
The role of limbic system irritability in linking history of childhood maltreatment and psychiatric outcomes in low-income, high-risk women: moderation by FK506 binding protein 5 haplotype. Dev Psychopathol (2012) 0.85
Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications. Neuropsychopharmacology (2015) 0.84
Stress-related genes and heroin addiction: a role for a functional FKBP5 haplotype. Psychoneuroendocrinology (2014) 0.84
Role of Environmental Confounding in the Association between FKBP5 and First-Episode Psychosis. Front Psychiatry (2014) 0.83
Gene-environment interaction in major depression: focus on experience-dependent biological systems. Front Psychiatry (2015) 0.82
FKBP5 genotype-dependent DNA methylation and mRNA regulation after psychosocial stress in remitted depression and healthy controls. Int J Neuropsychopharmacol (2014) 0.82
Mind and body: how the health of the body impacts on neuropsychiatry. Front Pharmacol (2013) 0.82
RDoC and translational perspectives on the genetics of trauma-related psychiatric disorders. Am J Med Genet B Neuropsychiatr Genet (2015) 0.80
Childhood maltreatment and stress-related psychopathology: the epigenetic memory hypothesis. Curr Pharm Des (2015) 0.80
Life course epidemiology of trauma and related psychopathology in civilian populations. Curr Psychiatry Rep (2015) 0.79
Dexamethasone Treatment Leads to Enhanced Fear Extinction and Dynamic Fkbp5 Regulation in Amygdala. Neuropsychopharmacology (2015) 0.79
HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS. Depress Anxiety (2015) 0.79
Antidepressant treatment response is modulated by genetic and environmental factors and their interactions. Ann Gen Psychiatry (2014) 0.78
The prevalence and psychosocial correlates of suicide attempts among inpatient adolescent offspring of Croatian PTSD male war veterans. Child Psychiatry Hum Dev (2014) 0.78
Schizophrenia in the spectrum of gene-stress interactions: the FKBP5 example. Schizophr Bull (2015) 0.77
Cross-cultural gene- environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia. Int Rev Psychiatry (2015) 0.77
Glucocorticoids, epigenetic control and stress resilience. Neurobiol Stress (2014) 0.77
Psychiatric symptoms in adolescents: FKBP5 genotype-early life adversity interaction effects. Eur Child Adolesc Psychiatry (2015) 0.76
The common functional FKBP5 variant rs1360780 is associated with altered cognitive function in aged individuals. Sci Rep (2014) 0.76
CREB1 gene polymorphisms combined with environmental risk factors increase susceptibility to major depressive disorder (MDD). Int J Clin Exp Pathol (2015) 0.76
Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance. PLoS One (2014) 0.76
FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students. Am J Med Genet B Neuropsychiatr Genet (2016) 0.76
Hsp90 and FKBP51: complex regulators of psychiatric diseases. Philos Trans R Soc Lond B Biol Sci (2018) 0.76
FKBP5 polymorphisms influence pre-learning stress-induced alterations of learning and memory. Eur J Neurosci (2017) 0.75
Understanding epigenetic architecture of suicide neurobiology: A critical perspective. Neurosci Biobehav Rev (2016) 0.75
Abuse-related trauma forward medical care in a randomly sampled nationwide population. Medicine (Baltimore) (2016) 0.75
Steroid Receptor-Associated Immunophilins: A Gateway to Steroid Signalling. Clin Biochem Rev (2015) 0.75
Developmental pathways from child maltreatment to adolescent marijuana dependence: Examining moderation by FK506 binding protein 5 gene (FKBP5). Dev Psychopathol (2015) 0.75
FKBP5 DNA methylation does not mediate the association between childhood maltreatment and depression symptom severity in the Detroit Neighborhood Health Study. J Psychiatr Res (2017) 0.75
Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis. J Affect Disord (2017) 0.75
Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD. Am J Med Genet B Neuropsychiatr Genet (2017) 0.75
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61
Development and validation of a brief screening version of the Childhood Trauma Questionnaire. Child Abuse Negl (2003) 10.07
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry (2001) 7.80
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA (2008) 6.60
The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology (2000) 5.14
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry (2008) 4.65
Cohort profile: the study of health in Pomerania. Int J Epidemiol (2010) 4.38
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet (2004) 3.91
Study of Health In Pomerania (SHIP): a health examination survey in an east German region: objectives and design. Soz Praventivmed (2001) 3.17
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology (2009) 3.01
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J Biol Chem (2004) 2.91
Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology (2010) 2.16
Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden. Mol Psychiatry (2005) 2.06
Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability. J Clin Endocrinol Metab (2003) 1.92
On the estimation of additive interaction by use of the four-by-two table and beyond. Am J Epidemiol (2008) 1.91
Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls. Eur J Neurosci (2008) 1.88
The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. Biol Psychiatry (2008) 1.86
Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide. Neuropsychopharmacology (2010) 1.68
The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety. J Psychiatr Res (1999) 1.65
Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects. Neuropsychopharmacology (2004) 1.41
Serotonin transporter gene (SLC6A4) promoter polymorphisms and the susceptibility to posttraumatic stress disorder in the general population. Am J Psychiatry (2009) 1.36
Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression. a prospective study. J Psychiatr Res (2001) 1.31
[The German version of the Childhood Trauma Questionnaire (CTQ): preliminary psychometric properties]. Psychother Psychosom Med Psychol (2010) 1.29
Genetic variability at HPA axis in major depression and clinical response to antidepressant treatment. J Affect Disord (2007) 1.11
FKBP5 and resistant attachment predict cortisol reactivity in infants: gene-environment interaction. Psychoneuroendocrinology (2010) 1.04
Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits. BMC Psychiatry (2006) 0.96
Relative excess risk due to interaction: resampling-based confidence intervals. Epidemiology (2010) 0.88
Update on the 2005 paper: moderation of mental and physical distress by polymorphisms in the 5-HT transporter gene by interacting with social stressors and chronic disease burden. Mol Psychiatry (2010) 0.82
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet (2008) 6.26
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nat Genet (2008) 4.67
Cohort profile: the study of health in Pomerania. Int J Epidemiol (2010) 4.38
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Am J Hum Genet (2007) 3.31
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA (2013) 3.15
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
The predictive value of different measures of obesity for incident cardiovascular events and mortality. J Clin Endocrinol Metab (2010) 3.12
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease. Nat Genet (2007) 2.75
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
A 4-item measure of depression and anxiety: validation and standardization of the Patient Health Questionnaire-4 (PHQ-4) in the general population. J Affect Disord (2009) 2.68
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
Continuous individual support of smoking cessation using text messaging: a pilot experimental study. Nicotine Tob Res (2009) 2.46
Sex and the risk of restless legs syndrome in the general population. Arch Intern Med (2004) 2.43
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet (2010) 2.24
Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med (2012) 2.24
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA (2009) 2.10
Hepatitis B and C virus infection and the risk of atherosclerosis in a general population. Atherosclerosis (2004) 2.01
Association of periodontitis with the risk of oral leukoplakia. Oral Oncol (2012) 1.99
Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nat Genet (2011) 1.98
Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Hepatology (2009) 1.97