Published in BMC Syst Biol on June 20, 2011
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. Pharmacol Ther (2013) 2.64
Herb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulae. BMC Bioinformatics (2010) 2.00
Retracted Predicting new molecular targets for rhein using network pharmacology. BMC Syst Biol (2012) 1.55
TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. J Cheminform (2014) 1.19
Network-based drug discovery by integrating systems biology and computational technologies. Brief Bioinform (2012) 1.09
An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin. Evid Based Complement Alternat Med (2013) 1.06
A network study of chinese medicine xuesaitong injection to elucidate a complex mode of action with multicompound, multitarget, and multipathway. Evid Based Complement Alternat Med (2013) 0.97
A systems biology approach to uncovering pharmacological synergy in herbal medicines with applications to cardiovascular disease. Evid Based Complement Alternat Med (2012) 0.92
Synergistic and antagonistic drug combinations depend on network topology. PLoS One (2014) 0.92
Identifying roles of "Jun-Chen-Zuo-Shi" component herbs of QiShenYiQi formula in treating acute myocardial ischemia by network pharmacology. Chin Med (2014) 0.91
Exploring drug combinations in genetic interaction network. BMC Bioinformatics (2012) 0.91
A systems biology-based investigation into the pharmacological mechanisms of wu tou tang acting on rheumatoid arthritis by integrating network analysis. Evid Based Complement Alternat Med (2013) 0.91
21st century natural product research and drug development and traditional medicines. Nat Prod Rep (2013) 0.90
Network pharmacology: a new approach for chinese herbal medicine research. Evid Based Complement Alternat Med (2013) 0.89
Bioinformatics opportunities for identification and study of medicinal plants. Brief Bioinform (2012) 0.88
Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model. PLoS One (2012) 0.87
A strategy for the identification of combinatorial bioactive compounds contributing to the holistic effect of herbal medicines. Sci Rep (2015) 0.86
Vitexicarpin acts as a novel angiogenesis inhibitor and its target network. Evid Based Complement Alternat Med (2013) 0.85
NLLSS: Predicting Synergistic Drug Combinations Based on Semi-supervised Learning. PLoS Comput Biol (2016) 0.85
Material basis of Chinese herbal formulas explored by combining pharmacokinetics with network pharmacology. PLoS One (2013) 0.84
Combining ZHENG Theory and High-Throughput Expression Data to Predict New Effects of Chinese Herbal Formulae. Evid Based Complement Alternat Med (2012) 0.84
Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae. Int J Mol Sci (2015) 0.83
Navigating traditional chinese medicine network pharmacology and computational tools. Evid Based Complement Alternat Med (2013) 0.83
Understanding the molecular mechanism of interventions in treating rheumatoid arthritis patients with corresponding traditional chinese medicine patterns based on bioinformatics approach. Evid Based Complement Alternat Med (2012) 0.83
Deciphering the pharmacological mechanism of the Chinese formula huanglian-jie-du decoction in the treatment of ischemic stroke using a systems biology-based strategy. Acta Pharmacol Sin (2015) 0.82
Dissection of protein interactomics highlights microRNA synergy. PLoS One (2013) 0.82
DCDB 2.0: a major update of the drug combination database. Database (Oxford) (2014) 0.82
The anti-tumor histone deacetylase inhibitor SAHA and the natural flavonoid curcumin exhibit synergistic neuroprotection against amyloid-beta toxicity. PLoS One (2014) 0.81
A computational drug-target network for yuanhu zhitong prescription. Evid Based Complement Alternat Med (2013) 0.81
Network-based biomarkers for cold coagulation blood stasis syndrome and the therapeutic effects of shaofu zhuyu decoction in rats. Evid Based Complement Alternat Med (2013) 0.80
A Module Analysis Approach to Investigate Molecular Mechanism of TCM Formula: A Trial on Shu-feng-jie-du Formula. Evid Based Complement Alternat Med (2013) 0.80
Impact of fixed-dose combination of germacrone, curdione, and furanodiene on breast cancer cell proliferation. Cell J (2013) 0.79
Cancer classification: Mutual information, target network and strategies of therapy. J Clin Bioinforma (2012) 0.79
An effective solution to discover synergistic drugs for anti-cerebral ischemia from traditional Chinese medicinal formulae. PLoS One (2013) 0.79
Diverse array-designed modes of combination therapies in Fangjiomics. Acta Pharmacol Sin (2015) 0.79
Synergism and rules of the new combination drug Yiqijiedu formulae (YQJD) on ischemic stroke based on amino acids (AAs) metabolism. Sci Rep (2014) 0.79
Optimizing combinations of flavonoids deriving from astragali radix in activating the regulatory element of erythropoietin by a feedback system control scheme. Evid Based Complement Alternat Med (2013) 0.79
Botanicals and Their Bioactive Phytochemicals for Women's Health. Pharmacol Rev (2016) 0.78
An analysis of chemical ingredients network of Chinese herbal formulae for the treatment of coronary heart disease. PLoS One (2015) 0.78
Proteomic Identification of Nrf2-Mediated Phase II Enzymes Critical for Protection of Tao Hong Si Wu Decoction against Oxygen Glucose Deprivation Injury in PC12 Cells. Evid Based Complement Alternat Med (2014) 0.78
A Network-Based Target Overlap Score for Characterizing Drug Combinations: High Correlation with Cancer Clinical Trial Results. PLoS One (2015) 0.77
A Drug-Target Network-Based Approach to Evaluate the Efficacy of Medicinal Plants for Type II Diabetes Mellitus. Evid Based Complement Alternat Med (2013) 0.77
An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases. Acta Pharmacol Sin (2015) 0.77
Study on incompatibility of traditional chinese medicine: evidence from formula network, chemical space, and metabolism room. Evid Based Complement Alternat Med (2013) 0.76
An Integrative Thrombosis Network: Visualization and Topological Analysis. Evid Based Complement Alternat Med (2015) 0.76
Protective effect of Daming capsule against chronic cerebral ischemia. BMC Complement Altern Med (2015) 0.76
Matrix Factorization-Based Prediction of Novel Drug Indications by Integrating Genomic Space. Comput Math Methods Med (2015) 0.76
Systematic synergy modeling: understanding drug synergy from a systems biology perspective. BMC Syst Biol (2015) 0.76
Systems pharmacology exploration of botanic drug pairs reveals the mechanism for treating different diseases. Sci Rep (2016) 0.76
Validated RP-HPLC method for simultaneous determination and quantification of chlorpheniramine maleate, paracetamol and caffeine in tablet formulation. Springerplus (2016) 0.75
Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response. Sci Rep (2017) 0.75
Transcriptional Regulation of CYP3A4/2B6/2C9 Mediated via Nuclear Receptor PXR by Helicid and Its Metabolites. Evid Based Complement Alternat Med (2015) 0.75
Systems Pharmacology Based Study of the Molecular Mechanism of SiNiSan Formula for Application in Nervous and Mental Diseases. Evid Based Complement Alternat Med (2016) 0.75
The Combination of Three Components Derived from Sheng MaiSan Protects Myocardial Ischemic Diseases and Inhibits Oxidative Stress via Modulating MAPKs and JAK2-STAT3 Signaling Pathways Based on Bioinformatics Approach. Front Pharmacol (2017) 0.75
A partial pathway- and network-based transformation reveals the synergistic mechanism of JA and UA against cerebral ischemia-reperfusion injury. Protein Cell (2014) 0.75
Prediction of drugs having opposite effects on disease genes in a directed network. BMC Syst Biol (2016) 0.75
Bioregulatory systems medicine: an innovative approach to integrating the science of molecular networks, inflammation, and systems biology with the patient's autoregulatory capacity? Front Physiol (2015) 0.75
Systems psychopharmacology: A network approach to developing novel therapies. World J Psychiatry (2016) 0.75
Herb Network Analysis for a Famous TCM Doctor's Prescriptions on Treatment of Rheumatoid Arthritis. Evid Based Complement Alternat Med (2015) 0.75
System-level study on synergism and antagonism of active ingredients in traditional Chinese medicine by using molecular imprinting technology. Sci Rep (2014) 0.75
System analysis of LWDH related genes based on text mining in biological networks. Biomed Res Int (2014) 0.75
Study on the Cytotoxic, Genotoxic and Clastogenic Potential of Attalea phalerata Mart. ex Spreng. Oil Pulp In Vitro and In Vivo Experimental Models. PLoS One (2016) 0.75
Toward a scientific understanding of the effectiveness, material basis and prescription compatibility of a Chinese herbal formula Dan-hong injection. Sci Rep (2017) 0.75
Visualization of network target crosstalk optimizes drug synergism in myocardial ischemia. PLoS One (2014) 0.75
Synergistic Synthetic Biology: Units in Concert. Front Bioeng Biotechnol (2013) 0.75
Natural formulas and the nature of formulas: Exploring potential therapeutic targets based on traditional Chinese herbal formulas. PLoS One (2017) 0.75
Chinese Herbal Medicine Meets Biological Networks of Complex Diseases: A Computational Perspective. Evid Based Complement Alternat Med (2017) 0.75
Innovating Chinese Herbal Medicine: From Traditional Health Practice to Scientific Drug Discovery. Front Pharmacol (2017) 0.75
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52
Bioconductor: open software development for computational biology and bioinformatics. Genome Biol (2004) 143.19
KEGG for linking genomes to life and the environment. Nucleic Acids Res (2007) 49.37
Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med (1995) 26.60
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
Network pharmacology: the next paradigm in drug discovery. Nat Chem Biol (2008) 8.51
Molecular networks as sensors and drivers of common human diseases. Nature (2009) 6.14
Network-based global inference of human disease genes. Mol Syst Biol (2008) 5.01
A text-mining analysis of the human phenome. Eur J Hum Genet (2006) 4.98
The problem of synergism and antagonism of combined drugs. Arzneimittelforschung (1953) 4.84
Assessing experimentally derived interactions in a small world. Proc Natl Acad Sci U S A (2003) 4.53
Multi-target therapeutics: when the whole is greater than the sum of the parts. Drug Discov Today (2006) 4.24
Multicomponent therapeutics for networked systems. Nat Rev Drug Discov (2005) 3.99
Systematic discovery of multicomponent therapeutics. Proc Natl Acad Sci U S A (2003) 3.86
Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc Natl Acad Sci U S A (2008) 3.71
Systems biology and combination therapy in the quest for clinical efficacy. Nat Chem Biol (2006) 3.63
Mechanisms of drug combinations: interaction and network perspectives. Nat Rev Drug Discov (2009) 3.20
Understanding ZHENG in traditional Chinese medicine in the context of neuro-endocrine-immune network. IET Syst Biol (2007) 3.05
The efficiency of multi-target drugs: the network approach might help drug design. Trends Pharmacol Sci (2005) 3.02
Criteria for analyzing interactions between biologically active agents. Adv Cancer Res (1981) 2.49
Cancer as a robust system: implications for anticancer therapy. Nat Rev Cancer (2004) 2.28
A global pathway crosstalk network. Bioinformatics (2008) 2.27
Strategies for optimizing combinations of molecularly targeted anticancer agents. Nat Rev Drug Discov (2006) 2.23
Synergy and other interactions in phytomedicines. Phytomedicine (2001) 2.06
Herb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulae. BMC Bioinformatics (2010) 2.00
The regulatory crosstalk between kinases and proteases in cancer. Nat Rev Cancer (2010) 1.80
Identification of information flow-modulating drug targets: a novel bridging paradigm for drug discovery. Clin Pharmacol Ther (2008) 1.77
Proteins, drug targets and the mechanisms they control: the simple truth about complex networks. Nat Rev Drug Discov (2007) 1.73
Revisiting the ancient concept of botanical therapeutics. Nat Chem Biol (2007) 1.71
Network systems biology for drug discovery. Clin Pharmacol Ther (2010) 1.69
Protein-protein interaction networks and biology--what's the connection? Nat Biotechnol (2008) 1.69
Network-based relating pharmacological and genomic spaces for drug target identification. PLoS One (2010) 1.68
Navigating the network: signaling cross-talk in hematopoietic cells. Nat Immunol (2009) 1.48
A global view of drug-therapy interactions. BMC Pharmacol (2008) 1.34
Constructing biological networks through combined literature mining and microarray analysis: a LMMA approach. Bioinformatics (2006) 1.33
Disease-aging network reveals significant roles of aging genes in connecting genetic diseases. PLoS Comput Biol (2009) 1.32
Angiogenesis: from plants to blood vessels. Trends Pharmacol Sci (2006) 1.28
High-order combination effects and biological robustness. Mol Syst Biol (2008) 1.24
Comparing classical pathways and modern networks: towards the development of an edge ontology. Trends Biochem Sci (2007) 1.23
Chemogenomic profiling predicts antifungal synergies. Mol Syst Biol (2009) 1.11
The calculation of microbial assays. Bacteriol Rev (1956) 1.11
Co-targeting insulin-like growth factor I receptor and HER2: dramatic effects of HER2 inhibitors on nonoverexpressing breast cancer. Cancer Res (2008) 1.07
Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells. Eur J Cancer (2001) 1.05
Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy. Clin Cancer Res (2004) 1.02
A formal model for analyzing drug combination effects and its application in TNF-alpha-induced NFkappaB pathway. BMC Syst Biol (2010) 0.99
Detection of characteristic sub pathway network for angiogenesis based on the comprehensive pathway network. BMC Bioinformatics (2010) 0.99
Principles: mechanisms and modeling of synergism in cellular responses. Trends Pharmacol Sci (2005) 0.93
Suppressive effects of a Chinese herbal medicine qing-luo-yin extract on the angiogenesis of collagen-induced arthritis in rats. Am J Chin Med (2003) 0.91
Statins and cancer--beyond the "one drug, one disease" model. N Engl J Med (2005) 0.88
Drug effects viewed from a signal transduction network perspective. J Med Chem (2009) 0.87
Prediction of in vivo synergistic activity of antiangiogenic compounds by gene expression profiling. Cancer Res (2002) 0.85
Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells. Neurochem Res (2010) 0.82
Synergistic effects of protein tyrosine kinase inhibitor genistein with camptothecins against three cell lines in vitro. Cancer Lett (2006) 0.82
Camptothecin analogues and vinblastine in the treatment of renal cell carcinoma: an in vivo study using a human orthotopic renal cancer xenograft. Urol Oncol (2003) 0.81
Vinblastine and 5-fluorouracil sensitivity of xenografts of four pancreatic ductal adenocarcinomas: is there a correlation with histological and cytological tumour differentiation? Virchows Arch (1995) 0.79
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. Lancet (2008) 9.03
Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol (2011) 8.34
Genome sequence and analysis of the tuber crop potato. Nature (2011) 7.77
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
The Norway spruce genome sequence and conifer genome evolution. Nature (2013) 4.74
H5N1 infection of the respiratory tract and beyond: a molecular pathology study. Lancet (2007) 4.62
Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis. J Virol (2005) 3.31
Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet (2010) 3.02
Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy. J Genet Genomics (2012) 2.98
Highly efficient genome modifications mediated by CRISPR/Cas9 in Drosophila. Genetics (2013) 2.87
Heat Loss Prevention (HeLP) in the delivery room: A randomized controlled trial of polyethylene occlusive skin wrapping in very preterm infants. J Pediatr (2004) 2.73
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res (2013) 2.73
TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nat Methods (2013) 2.64
Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution. PLoS One (2011) 2.29
An adenosine nucleoside inhibitor of dengue virus. Proc Natl Acad Sci U S A (2009) 2.20
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation. J Neurosci (2013) 2.04
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Nat Genet (2012) 2.02
Herb network construction and co-module analysis for uncovering the combination rule of traditional Chinese herbal formulae. BMC Bioinformatics (2010) 2.00
Interference-free determination of ischemia-modified albumin using quantum dot coupled X-ray fluorescence spectroscopy. Biosens Bioelectron (2013) 1.97
Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proc Natl Acad Sci U S A (2007) 1.96
Local elastic properties of a metallic glass. Nat Mater (2011) 1.88
HIF-1α and HIF-2α correlate with migration and invasion in gastric cancer. Cancer Biol Ther (2010) 1.83
Genotype-phenotype correlations in alternating hemiplegia of childhood. Neurology (2014) 1.82
Imaging findings of biliary hamartomas. World J Gastroenterol (2005) 1.77
Three-column fixation for complex tibial plateau fractures. J Orthop Trauma (2010) 1.73
Expression of human apoAII in transgenic rabbits leads to dyslipidemia: a new model for combined hyperlipidemia. Arterioscler Thromb Vasc Biol (2009) 1.64
Randomized head-to-head comparison of pitavastatin, atorvastatin, and rosuvastatin for safety and efficacy (quantity and quality of LDL): the PATROL trial. Circ J (2011) 1.64
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nat Genet (2013) 1.64
Genetic structure and diversity of cultivated soybean (Glycine max (L.) Merr.) landraces in China. Theor Appl Genet (2008) 1.62
Pancreatic stump-closed pancreaticojejunostomy can be performed safely in normal soft pancreas cases. J Surg Res (2011) 1.61
CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. Proc Natl Acad Sci U S A (2008) 1.60
Making the cut: protease-mediated regulation of angiogenesis. Exp Cell Res (2006) 1.59
Multiple organ infection and the pathogenesis of SARS. J Exp Med (2005) 1.58
Changes of Esophagogastric Junctional Adenocarcinoma and Gastroesophageal Reflux Disease Among Surgical Patients During 1988-2012: A Single-institution, High-volume Experience in China. Ann Surg (2016) 1.57
Analysis of metabolomic PCA data using tree diagrams. Anal Biochem (2009) 1.57
Hydrogen peroxide in plants: a versatile molecule of the reactive oxygen species network. J Integr Plant Biol (2008) 1.55
Fluoxetine administered to juvenile monkeys: effects on the serotonin transporter and behavior. Am J Psychiatry (2014) 1.54
Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4. PLoS One (2011) 1.54
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3. Mol Cancer Ther (2012) 1.53
Detection of nucleic acids with graphene nanopores: ab initio characterization of a novel sequencing device. Nano Lett (2010) 1.53
Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex. Hum Mol Genet (2010) 1.53
Synthetic human parathyroid hormone 1-34 replacement therapy: a randomized crossover trial comparing pump versus injections in the treatment of chronic hypoparathyroidism. J Clin Endocrinol Metab (2011) 1.50
Distinct RNA elements confer specificity to flavivirus RNA cap methylation events. J Virol (2007) 1.48
Tumor necrosis factor alpha protects against lethal West Nile virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system. J Virol (2008) 1.48
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Res (2013) 1.48
Impact of glycemic control on the clinical outcome in diabetic patients with percutaneous coronary intervention--from the FU-registry. Circ J (2011) 1.45
An efficient and effective region-based image retrieval framework. IEEE Trans Image Process (2004) 1.45
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer. Proc Natl Acad Sci U S A (2012) 1.44
West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism. J Virol (2008) 1.44
Lifestyle changes through the use of delivered meals and dietary counseling in a single-blind study. The STYLIST study. Circ J (2012) 1.44
Antiproliferative, antiinvasive, and proapoptotic activity of folate receptor α-targeted liposomal doxorubicin in nonfunctional pituitary adenoma cells. Endocrinology (2013) 1.43
Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells. BMC Mol Biol (2009) 1.42
MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11. FEBS Lett (2011) 1.40
Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease. Nat Genet (2009) 1.40
TALEN or Cas9 - rapid, efficient and specific choices for genome modifications. J Genet Genomics (2013) 1.40
Traditional Chinese medicine network pharmacology: theory, methodology and application. Chin J Nat Med (2013) 1.39
C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance. Am J Pathol (2005) 1.37
Coordinated regulation of anthocyanin biosynthesis in Chinese bayberry (Myrica rubra) fruit by a R2R3 MYB transcription factor. Planta (2010) 1.36
Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. EMBO J (2003) 1.33
Flavivirus methyltransferase: a novel antiviral target. Antiviral Res (2008) 1.31
Cost-effectiveness analysis of chemotherapy for advanced gastric cancer in China. World J Gastroenterol (2008) 1.31
Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range. Nat Commun (2011) 1.30
NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist. Proc Natl Acad Sci U S A (2009) 1.30
A study of cycling induced degradation mechanisms in Si nanocrystal memory devices. Nanotechnology (2011) 1.30
The soybean Dof-type transcription factor genes, GmDof4 and GmDof11, enhance lipid content in the seeds of transgenic Arabidopsis plants. Plant J (2007) 1.29
Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion. J Exp Clin Cancer Res (2010) 1.28
Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Dev Biol (2007) 1.26
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis. J Bacteriol (2010) 1.25
Not just 'a few wisps': real-time measurement of tobacco smoke at entrances to office buildings. Tob Control (2010) 1.25
Correlation between serum CA724 and gastric cancer: multiple analyses based on Chinese population. Mol Biol Rep (2012) 1.24
Prodrugs forming high drug loading multifunctional nanocapsules for intracellular cancer drug delivery. J Am Chem Soc (2010) 1.24
Total vs. proximal gastrectomy for proximal gastric cancer: a systematic review and meta-analysis. Hepatogastroenterology (2012) 1.24
Mutations of neuronal voltage-gated Na+ channel alpha 1 subunit gene SCN1A in core severe myoclonic epilepsy in infancy (SMEI) and in borderline SMEI (SMEB). Epilepsia (2004) 1.24
Reference gene selection for quantitative real-time polymerase chain reaction in Populus. Anal Biochem (2010) 1.23
Effects of a randomized contingency management intervention on opiate abstinence and retention in methadone maintenance treatment in China. Addiction (2011) 1.22
Improvement of Aspergillus sulphureus endo-beta-1,4-xylanase expression in Pichia pastoris by codon optimization and analysis of the enzymic characterization. Appl Biochem Biotechnol (2009) 1.22
Human bone marrow mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitro. Differentiation (2009) 1.22
NAT10, a nucleolar protein, localizes to the midbody and regulates cytokinesis and acetylation of microtubules. Exp Cell Res (2009) 1.21
Correlation of atomic cluster symmetry and glass-forming ability of metallic glass. Phys Rev Lett (2007) 1.21
Terminal structures of West Nile virus genomic RNA and their interactions with viral NS5 protein. Virology (2008) 1.20
Population variation of West Nile virus confers a host-specific fitness benefit in mosquitoes. Virology (2010) 1.20
Comparable clinical outcomes and live births after single vitrified-warmed and fresh blastocyst transfer. Reprod Biomed Online (2012) 1.19
Exclusion of West Nile virus superinfection through RNA replication. J Virol (2009) 1.19
Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway. Cancer Lett (2008) 1.19
Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer. Gigascience (2012) 1.18
Rapid and deep human proteome analysis by single-dimension shotgun proteomics. Mol Cell Proteomics (2013) 1.16
Impediment of E. coli UvrD by DNA-destabilizing force reveals a strained-inchworm mechanism of DNA unwinding. EMBO J (2008) 1.16
The ethylene receptor ETR2 delays floral transition and affects starch accumulation in rice. Plant Cell (2009) 1.16
Curcumin polymers as anticancer conjugates. Biomaterials (2010) 1.16
Processing body and stress granule assembly occur by independent and differentially regulated pathways in Saccharomyces cerevisiae. Genetics (2012) 1.16
Various applications of TALEN- and CRISPR/Cas9-mediated homologous recombination to modify the Drosophila genome. Biol Open (2014) 1.16
Increased CD14(+)HLA-DR (-/low) myeloid-derived suppressor cells correlate with extrathoracic metastasis and poor response to chemotherapy in non-small cell lung cancer patients. Cancer Immunol Immunother (2013) 1.15
Biomimetic antireflective Si nanopillar arrays. Small (2008) 1.15
Ionic conductivity of the aqueous layer separating a lipid bilayer membrane and a glass support. Langmuir (2006) 1.15