Published in Exp Mol Pathol on June 12, 2011
Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height. Hum Mol Genet (2012) 1.87
Aberrantly expressed long noncoding RNAs in human intervertebral disc degeneration: a microarray related study. Arthritis Res Ther (2014) 1.13
Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration. J Biol Chem (2012) 0.99
An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes. Arthritis Res Ther (2013) 0.89
Excessive Activation of TGFβ by Spinal Instability Causes Vertebral Endplate Sclerosis. Sci Rep (2016) 0.77
The role of matrix metalloproteinase 14 polymorphisms in susceptibility to intervertebral disc degeneration in the Chinese Han population. Arch Med Sci (2015) 0.76
Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis. Bone Res (2017) 0.75
Landscape of RNAs in human lumbar disc degeneration. Oncotarget (2016) 0.75
Effects of initial boost with TGF-beta 1 and grade of intervertebral disc degeneration on 3D culture of human annulus fibrosus cells. J Orthop Surg Res (2014) 0.75
Isolation and characterisation of a recombinant antibody fragment that binds NCAM1-expressing intervertebral disc cells. PLoS One (2013) 0.75
Autologous intervertebral disc cell implantation: a model using Psammomys obesus, the sand rat. Spine (Phila Pa 1976) (2002) 1.50
Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated beta-galactosidase in human and sand rat discs. Spine (Phila Pa 1976) (2007) 1.46
Adipose-derived stem cells: characterization and current application in orthopaedic tissue repair. Exp Biol Med (Maywood) (2009) 1.37
Calcium deposition in osteoarthritic meniscus and meniscal cell culture. Arthritis Res Ther (2010) 1.27
Vertebral endplate architecture and vascularization: application of micro-computerized tomography, a vascular tracer, and immunocytochemistry in analyses of disc degeneration in the aging sand rat. Spine (Phila Pa 1976) (2005) 1.27
An AOA critical issue. Disc replacements: this time will we really cure low-back and neck pain? J Bone Joint Surg Am (2004) 1.24
Three-dimensional culture of human disc cells within agarose or a collagen sponge: assessment of proteoglycan production. Biomaterials (2005) 1.17
Analysis of meniscal degeneration and meniscal gene expression. BMC Musculoskelet Disord (2010) 1.17
Ultrastructure of the human intervertebral disc during aging and degeneration: comparison of surgical and control specimens. Spine (Phila Pa 1976) (2002) 1.15
The sand rat model for disc degeneration: radiologic characterization of age-related changes: cross-sectional and prospective analyses. Spine (Phila Pa 1976) (2002) 1.13
Cell-based tissue engineering for the intervertebral disc: in vitro studies of human disc cell gene expression and matrix production within selected cell carriers. Spine J (2004) 1.11
Targeted deletion of the SPARC gene accelerates disc degeneration in the aging mouse. J Histochem Cytochem (2005) 1.07
The SOX9 transcription factor in the human disc: decreased immunolocalization with age and disc degeneration. Spine (Phila Pa 1976) (2005) 1.03
Fukutin-related protein is essential for mouse muscle, brain and eye development and mutation recapitulates the wide clinical spectrums of dystroglycanopathies. Hum Mol Genet (2010) 0.98
Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc. Arthritis Res Ther (2009) 0.97
Recent advances in disc cell biology. Spine (Phila Pa 1976) (2003) 0.97
Biologic strategies for the therapy of intervertebral disc degeneration. Expert Opin Biol Ther (2003) 0.96
Histological examination of collagen and proteoglycan changes in osteoarthritic menisci. Open Rheumatol J (2012) 0.95
Mitochondrial gene expression in the human annulus: in vivo data from annulus cells and selectively harvested senescent annulus cells. Spine J (2011) 0.94
Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix. Arthritis Res Ther (2008) 0.93
Increased cell senescence is associated with decreased cell proliferation in vivo in the degenerating human annulus. Spine J (2008) 0.93
Microarray analysis of laser capture microdissected-anulus cells from the human intervertebral disc. Spine (Phila Pa 1976) (2007) 0.93
Observations on morphologic changes in the aging and degenerating human disc: secondary collagen alterations. BMC Musculoskelet Disord (2002) 0.92
Brain-derived neurotrophic factor and its receptor in the human and the sand rat intervertebral disc. Arthritis Res Ther (2008) 0.92
1,25(OH)2-vitamin D3 inhibits proliferation and decreases production of monocyte chemoattractant protein-1, thrombopoietin, VEGF, and angiogenin by human annulus cells in vitro. Spine (Phila Pa 1976) (2008) 0.91
Genome-wide analysis of pain-, nerve- and neurotrophin -related gene expression in the degenerating human annulus. Mol Pain (2012) 0.91
Deleterious effects of discography radiocontrast solution on human annulus cell in vitro: changes in cell viability, proliferation, and apoptosis in exposed cells. Spine J (2012) 0.90
IGF-1 rescues human intervertebral annulus cells from in vitro stress-induced premature senescence. Growth Factors (2008) 0.89
Three-dimensional culture of human meniscal cells: extracellular matrix and proteoglycan production. BMC Biotechnol (2008) 0.89
Immunolocalization of thrombospondin in the human and sand rat intervertebral disc. Spine (Phila Pa 1976) (2006) 0.88
Leptin expression by annulus cells in the human intervertebral disc. Spine J (2007) 0.88
Culture of human anulus fibrosus cells on polyamide nanofibers: extracellular matrix production. Spine (Phila Pa 1976) (2009) 0.88
Demographic factors that influence human disc cell proliferation in vitro. Spine J (2006) 0.87
Vertebral endplate and disc changes in the aging sand rat lumbar spine: cross-sectional analyses of a large male and female population. Spine (Phila Pa 1976) (2007) 0.85
Human adipose-derived mesenchymal stem cells: direction to a phenotype sharing similarities with the disc, gene expression profiling, and coculture with human annulus cells. Tissue Eng Part A (2010) 0.85
Cellular, but not matrix, immunolocalization of SPARC in the human intervertebral disc: decreasing localization with aging and disc degeneration. Spine (Phila Pa 1976) (2004) 0.85
Expression and localization of estrogen receptor-beta in annulus cells of the human intervertebral disc and the mitogenic effect of 17-beta-estradiol in vitro. BMC Musculoskelet Disord (2002) 0.85
Autophagy in the Degenerating Human Intervertebral Disc: In Vivo Molecular and Morphological Evidence, and Induction of Autophagy in Cultured Annulus Cells Exposed to Proinflammatory Cytokines-Implications for Disc Degeneration. Spine (Phila Pa 1976) (2015) 0.84
Analysis of cell death and vertebral end plate bone mineral density in the annulus of the aging sand rat. Spine J (2007) 0.84
Constitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear factor-κB ligand. Arthritis Res Ther (2011) 0.84
Senescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis. BMC Biotechnol (2010) 0.83
Annulus cells from more degenerated human discs show modified gene expression in 3D culture compared with expression in cells from healthier discs. Spine J (2010) 0.83
Osteogenic and chondrogenic potential of biomembrane cells from the PMMA-segmental defect rat model. J Orthop Res (2012) 0.83
Computer aided vertebral visualization and analysis: a methodology using the sand rat, a small animal model of disc degeneration. BMC Musculoskelet Disord (2003) 0.82
Respiration and ROS production in brain and spinal cord mitochondria of transgenic rats with mutant G93a Cu/Zn-superoxide dismutase gene. Neurobiol Dis (2011) 0.82
Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs. Arthritis Res Ther (2009) 0.82