Jianping Ding

Author PubWeight™ 109.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 2011 13.16
2 Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science 2009 10.78
3 Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity. J Biol Chem 2004 6.55
4 Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3. Nucleic Acids Res 2006 2.09
5 Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir. Nat Struct Mol Biol 2004 1.78
6 Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure 2012 1.77
7 Optical orbital angular momentum from the curl of polarization. Phys Rev Lett 2010 1.68
8 Structural and molecular interactions of CCR5 inhibitors with CCR5. J Biol Chem 2006 1.55
9 Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H. Cell Res 2010 1.45
10 Molecular basis of the interaction of Saccharomyces cerevisiae Eaf3 chromo domain with methylated H3K36. J Biol Chem 2008 1.26
11 Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation. Protein Sci 2006 1.25
12 Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site. Biochem J 2007 1.23
13 Structural basis for the unique biological function of small GTPase RHEB. J Biol Chem 2005 1.19
14 Expression, purification, and characterization of SARS coronavirus RNA polymerase. Virology 2005 1.19
15 Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design. Nucleic Acids Res 2003 1.18
16 Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc Natl Acad Sci U S A 2009 1.13
17 Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins. J Mol Cell Biol 2011 1.13
18 Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20. Mol Immunol 2009 1.12
19 Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis. Nature 2013 1.11
20 Crystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activity. J Biol Chem 2003 1.10
21 Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector. Structure 2009 1.07
22 A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13. Blood 2011 1.06
23 Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Nat Struct Mol Biol 2010 1.04
24 Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding. Nucleic Acids Res 2011 1.04
25 Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication. EMBO J 2009 1.03
26 Structure of human tryptophanyl-tRNA synthetase in complex with tRNATrp reveals the molecular basis of tRNA recognition and specificity. Nucleic Acids Res 2006 1.02
27 The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14. Protein Sci 2006 1.02
28 Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis. Protein Sci 2008 1.02
29 Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations. J Biol Chem 2007 1.01
30 Structural basis for recognition of CD20 by therapeutic antibody Rituximab. J Biol Chem 2007 1.00
31 Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states. Nucleic Acids Res 2008 1.00
32 Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification. Cell Res 2012 0.99
33 Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274. Cell Res 2011 0.99
34 Generation of arbitrary vector beams with a spatial light modulator and a common path interferometric arrangement. Opt Lett 2007 0.98
35 Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel. Biophys J 2004 0.98
36 Steered molecular dynamics simulation on the binding of NNRTI to HIV-1 RT. Biophys J 2003 0.97
37 Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure. Virology 2009 0.95
38 Molecular basis of the acceleration of the GDP-GTP exchange of human ras homolog enriched in brain by human translationally controlled tumor protein. J Biol Chem 2009 0.94
39 Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay. Protein Sci 2008 0.94
40 A new type of vector fields with hybrid states of polarization. Opt Express 2010 0.94
41 Crystal structures of human NUDT5 reveal insights into the structural basis of the substrate specificity. J Mol Biol 2006 0.93
42 Crystal structure of D-Hydantoinase from Burkholderia pickettii at a resolution of 2.7 Angstroms: insights into the molecular basis of enzyme thermostability. J Bacteriol 2003 0.92
43 Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res 2013 0.91
44 X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis. FEBS J 2009 0.91
45 Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction. Protein Sci 2008 0.91
46 Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies. J Mol Biol 2008 0.91
47 Saccharomyces cerevisiae MHF complex structurally resembles the histones (H3-H4)₂ heterotetramer and functions as a heterotetramer. Structure 2012 0.89
48 Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination. Biochem J 2006 0.89
49 Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori. Proteins 2008 0.88
50 SWR1 complex poises heterochromatin boundaries for antisilencing activity propagation. Mol Cell Biol 2010 0.86
51 Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab. J Immunol 2009 0.86
52 Thioredoxin-like domain of human kappa class glutathione transferase reveals sequence homology and structure similarity to the theta class enzyme. Protein Sci 2005 0.84
53 Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism. Biochem J 2011 0.84
54 Modification of hepatitis C virus 1b RNA polymerase to make a highly active JFH1-type polymerase by mutation of the thumb domain. Arch Virol 2009 0.84
55 Involvement of the C-terminal proline-rich motif of G protein-coupled receptor kinases in recognition of activated rhodopsin. J Biol Chem 2004 0.84
56 The catalytic intermediate stabilized by a "down" active site loop for diaminopimelate decarboxylase from Helicobacter pylori. Enzymatic characterization with crystal structure analysis. J Biol Chem 2008 0.84
57 Generation of vector beam with space-variant distribution of both polarization and phase. Opt Lett 2011 0.83
58 Complete shaping of optical vector beams. Opt Express 2015 0.83
59 Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region. J Biol Chem 2007 0.83
60 Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide. Mol Immunol 2008 0.83
61 Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif. Biochem J 2013 0.83
62 Crystal structure of human copper homeostasis protein CutC reveals a potential copper-binding site. J Struct Biol 2009 0.83
63 Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans. Biochem J 2008 0.82
64 Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design. Nucleic Acids Res 2010 0.82
65 Optical trapping with focused Airy beams. Appl Opt 2011 0.82
66 A conserved hydrophobic core at Bcl-xL mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein. Arch Biochem Biophys 2009 0.81
67 Crystal structure of Pyrococcus horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase. Nucleic Acids Res 2009 0.81
68 Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization. BMC Microbiol 2009 0.81
69 Functional and structural characterization of DNMT2 from Spodoptera frugiperda. J Mol Cell Biol 2012 0.80
70 Molecular basis of the acetyltransferase activity of MEC-17 towards α-tubulin. Cell Res 2012 0.80
71 Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair. Nucleic Acids Res 2013 0.80
72 Structural basis of immunosuppression by the therapeutic antibody daclizumab. Cell Res 2010 0.80
73 Light field shaping by tailoring both phase and polarization. Appl Opt 2014 0.79
74 FDTD approach to optical forces of tightly focused vector beams on metal particles. Opt Express 2009 0.79
75 Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans. Biochem J 2009 0.79
76 Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis. J Mol Biol 2008 0.79
77 Radial Hilbert transform with Laguerre-Gaussian spatial filters. Opt Lett 2006 0.79
78 Distinct and redundant roles of the two MYST histone acetyltransferases Esa1 and Sas2 in cell growth and morphogenesis of Candida albicans. Eukaryot Cell 2013 0.78
79 Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase reveals insights into substrate recognition and catalytic mechanism. J Struct Biol 2013 0.78
80 Ultrastructural changes in goat interspecies and intraspecies reconstructed early embryos. Zygote 2008 0.78
81 Two-dimensional wavefront reconstruction from lateral multi-shear interferograms. Opt Express 2012 0.77
82 Structural modeling and biochemical studies reveal insights into the molecular basis of the recognition of beta-2-microglobulin by antibody BBM.1. J Mol Recognit 2009 0.76
83 Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism. Biochem J 2013 0.76
84 Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism. Biochem J 2011 0.76
85 New G-protein-coupled receptor structures provide insights into the recognition of CXCL12 and HIV-1 gp120 by CXCR4. Acta Biochim Biophys Sin (Shanghai) 2011 0.76
86 A lower baseline glomerular filtration rate predicts high mortality and newly cerebrovascular accidents in acute ischemic stroke patients. Medicine (Baltimore) 2017 0.75
87 Crystal structures of human CaMKIα reveal insights into the regulation mechanism of CaMKI. PLoS One 2012 0.75
88 Polarization structuring of focused field through polarization-only modulation of incident beam. Opt Lett 2010 0.75
89 Shaping of optical vector beams in three dimensions. Opt Lett 2017 0.75
90 Phase contrast Talbot array illuminators. Opt Lett 2008 0.75
91 Z-scan theory for material with two- and three-photon absorption. Opt Express 2005 0.75
92 Three-wave shearing interferometer based on spatial light modulator. Opt Express 2009 0.75
93 Saturation effect and forward-dominant second-harmonic generation in single-defect photonic crystals with dual localizations. Opt Lett 2006 0.75
94 [A new approach to wavelet-based P-wave detection]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2006 0.75
95 Mild encephalopathy with a reversible splenial lesion mimicking transient ischemic attack: A case report. Medicine (Baltimore) 2016 0.75
96 Expression, purification, crystallization and preliminary structural characterization of the GTPase domain of human Rheb. Acta Crystallogr D Biol Crystallogr 2004 0.75
97 Self-focusing hidden bar code. Appl Opt 2002 0.75
98 Reverse engineering approach to focus shaping. Opt Lett 2016 0.75
99 Generalized phase-shifting for three-wave shearing interferometry. Appl Opt 2016 0.75
100 A new planar left-handed metamaterial composed of metal-dielectric-metal structure. Opt Express 2008 0.75
101 Two-dimensional wave-front reconstruction from lateral shearing interferograms. Opt Express 2006 0.75
102 Polarization-selective diffractive optical elements with a twisted-nematic liquid-crystal display. Appl Opt 2010 0.75
103 Fibroblast cell line establishment, cryopreservation and interspecies embryos reconstruction in red panda ( Ailurus fulgens). Zygote 2009 0.75
104 Recovery of wavefront from multi-shear interferograms with different tilts. Opt Express 2014 0.75
105 Synthesis of Vinyl Trifluoromethyl Thioethers via Copper-Mediated Trifluoromethylthiolation of Vinyl Bromides. J Org Chem 2015 0.75