Published in J Cell Sci on June 21, 2011
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Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR). Open Biol (2013) 1.02
ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing. Genes Dev (2013) 1.01
Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet (2014) 0.92
Dot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptor. PLoS Genet (2013) 0.91
The budding yeast polo-like kinase Cdc5 regulates the Ndt80 branch of the meiotic recombination checkpoint pathway. Mol Biol Cell (2011) 0.88
Three distinct modes of Mec1/ATR and Tel1/ATM activation illustrate differential checkpoint targeting during budding yeast early meiosis. Mol Cell Biol (2013) 0.79
Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair. PLoS Biol (2016) 0.79
Senataxin controls meiotic silencing through ATR activation and chromatin remodeling. Cell Discov (2015) 0.77
S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex. Nucleic Acids Res (2016) 0.76
Phosphorylation of Mineralocorticoid Receptor Ligand Binding Domain Impairs Receptor Activation and Has a Dominant Negative Effect over Non-phosphorylated Receptors. J Biol Chem (2016) 0.75
Impact of histone H4K16 acetylation on the meiotic recombination checkpoint in Saccharomyces cerevisiae. Microb Cell (2016) 0.75
The Pch2 AAA+ ATPase promotes phosphorylation of the Hop1 meiotic checkpoint adaptor in response to synaptonemal complex defects. Nucleic Acids Res (2016) 0.75
Prevention of DNA Rereplication Through a Meiotic Recombination Checkpoint Response. G3 (Bethesda) (2016) 0.75
DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer. Oncogene (2017) 0.75
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery. Nature (2008) 4.33
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr Biol (2006) 2.02
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol (2013) 1.72
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Res (2004) 1.63
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease. J Cell Biol (2011) 1.53
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1. Proc Natl Acad Sci U S A (2004) 1.42
A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency. Mol Cell Proteomics (2010) 1.41
The human Rothmund-Thomson syndrome gene product, RECQL4, localizes to distinct nuclear foci that coincide with proteins involved in the maintenance of genome stability. J Cell Sci (2005) 1.38
Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding. J Virol (2008) 1.35
Mechanisms of ATR-mediated checkpoint signalling. Front Biosci (Landmark Ed) (2010) 1.34
Initiation and resolution of interhomolog connections: crossover and non-crossover sites along mouse synaptonemal complexes. J Cell Sci (2007) 1.31
TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint. Mol Biol Cell (2004) 1.21
HCLK2 is required for activity of the DNA damage response kinase ATR. J Biol Chem (2008) 1.17
Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis. PLoS Genet (2011) 1.07
Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast. J Cell Sci (2003) 1.07
The Dot1 histone methyltransferase and the Rad9 checkpoint adaptor contribute to cohesin-dependent double-strand break repair by sister chromatid recombination in Saccharomyces cerevisiae. Genetics (2009) 1.06
Bora and Aurora-A continue to activate Plk1 in mitosis. J Cell Sci (2013) 1.06
Mutant meiotic chromosome core components in mice can cause apparent sexual dimorphic endpoints at prophase or X-Y defective male-specific sterility. Chromosoma (2005) 1.02
Thoc1 deficiency compromises gene expression necessary for normal testis development in the mouse. Mol Cell Biol (2009) 1.01
Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection. Nucleic Acids Res (2013) 1.00
Opposing roles for 53BP1 during homologous recombination. Nucleic Acids Res (2013) 0.99
Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B. Transcription (2012) 0.99
TopBP1 localises to centrosomes in mitosis and to chromosome cores in meiosis. Chromosoma (2004) 0.98
Telomere and telomerase modulation by the mammalian Rad9/Rad1/Hus1 DNA-damage-checkpoint complex. Curr Biol (2006) 0.97
Role of Dot1 in the response to alkylating DNA damage in Saccharomyces cerevisiae: regulation of DNA damage tolerance by the error-prone polymerases Polzeta/Rev1. Genetics (2008) 0.96
Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis. J Cell Biol (2008) 0.92
Dot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptor. PLoS Genet (2013) 0.91
The Smc5-Smc6 complex is required to remove chromosome junctions in meiosis. PLoS One (2011) 0.89
Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress. Cell Cycle (2009) 0.89
Regulation of tolerance to DNA alkylating damage by Dot1 and Rad53 in Saccharomyces cerevisiae. DNA Repair (Amst) (2010) 0.89
The budding yeast polo-like kinase Cdc5 regulates the Ndt80 branch of the meiotic recombination checkpoint pathway. Mol Biol Cell (2011) 0.88
Reversal of PCNA ubiquitylation by Ubp10 in Saccharomyces cerevisiae. PLoS Genet (2012) 0.88
A convenient synthesis of C-22 and C-25 stereoisomers of cephalostatin north 1 side chain from spirostan sapogenins. Org Lett (2002) 0.88
Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance. PLoS Genet (2013) 0.86
Novel insights into maintaining genomic integrity: Wee1 regulating Mus81/Eme1. Cell Div (2011) 0.85
A Drosophila model of Menkes disease reveals a role for DmATP7 in copper absorption and neurodevelopment. Dis Model Mech (2009) 0.82
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. J Biol Chem (2005) 0.82
Expression of DNA damage checkpoint protein Hus1 in epithelial ovarian tumors correlates with prognostic markers. Int J Gynecol Pathol (2008) 0.81
Identification of herpesvirus proteins that contribute to G1/S arrest. J Virol (2014) 0.81
A modular approach to trim cellular targets in anticancer drug discovery. Bioorg Med Chem Lett (2011) 0.81
Rad9B responds to nucleolar stress through ATR and JNK signalling, and delays the G1-S transition. J Cell Sci (2012) 0.80
The fission yeast meiotic checkpoint kinase Mek1 regulates nuclear localization of Cdc25 by phosphorylation. Cell Cycle (2008) 0.80
The Hus1 homologue of Leishmania major encodes a nuclear protein that participates in DNA damage response. Mol Biochem Parasitol (2011) 0.79
Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes. Chromosoma (2013) 0.79
Intramolecular 1,5- versus 1,6-hydrogen abstraction reaction promoted by alkoxy radicals in carbohydrate models. Org Lett (2002) 0.78
The DNA damage checkpoint is activated during residual tumour cell survival to methotrexate treatment as an initial step of acquired drug resistance. Anticancer Drugs (2006) 0.76
Dub3 controls DNA damage signalling by direct deubiquitination of H2AX. Mol Oncol (2017) 0.75