Published in BMC Med Genomics on June 23, 2011
Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease. Mod Pathol (2013) 1.95
Genome-wide DNA methylation profiles in hepatocellular carcinoma. Hepatology (2012) 1.81
Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes. Epigenetics (2013) 1.29
A panel of genes methylated with high frequency in colorectal cancer. BMC Cancer (2014) 1.26
A genome-wide study of cytogenetic changes in colorectal cancer using SNP microarrays: opportunities for future personalized treatment. PLoS One (2012) 1.04
Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics (2013) 1.02
Interpretation of genome-wide infinium methylation data from ligated DNA in formalin-fixed, paraffin-embedded paired tumor and normal tissue. BMC Res Notes (2012) 1.02
Toward a comprehensive and systematic methylome signature in colorectal cancers. Epigenetics (2013) 1.00
Estimation of the fraction of cancer cells in a tumor DNA sample using DNA methylation. PLoS One (2013) 0.94
A two-gene blood test for methylated DNA sensitive for colorectal cancer. PLoS One (2015) 0.84
Identification of differentially methylated regions using streptavidin bisulfite ligand methylation enrichment (SuBLiME), a new method to enrich for methylated DNA prior to deep bisulfite genomic sequencing. Epigenetics (2012) 0.83
Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data. Oncol Rep (2015) 0.81
Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia. BMC Cancer (2015) 0.81
eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data. Cell Rep (2016) 0.81
DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia. Sci Rep (2016) 0.80
Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence. PLoS One (2014) 0.79
A Blood Test for Methylated BCAT1 and IKZF1 vs. a Fecal Immunochemical Test for Detection of Colorectal Neoplasia. Clin Transl Gastroenterol (2016) 0.78
Comments on: Interpretation of genome-wide infinium methylation data from ligated DNA in formalin-fixed paraffin-embedded paired tumor and normal tissue. BMC Res Notes (2012) 0.78
Comparative Correlation Structure of Colon Cancer Locus Specific Methylation: Characterisation of Patient Profiles and Potential Markers across 3 Array-Based Datasets. J Cancer (2015) 0.76
A cross-sectional study comparing a blood test for methylated BCAT1 and IKZF1 tumor-derived DNA with CEA for detection of recurrent colorectal cancer. Cancer Med (2016) 0.75
Epigenome variation in severe asthma. Biol Res Nurs (2014) 0.75
A robust data scaling algorithm to improve classification accuracies in biomedical data. BMC Bioinformatics (2016) 0.75
The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies. Int J Genomics (2017) 0.75
Aberrant methylation patterns in colorectal cancer: a meta-analysis. Oncotarget (2017) 0.75
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95
The fundamental role of epigenetic events in cancer. Nat Rev Genet (2002) 30.05
Cancer genes and the pathways they control. Nat Med (2004) 24.22
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet (2009) 18.90
The history of cancer epigenetics. Nat Rev Cancer (2004) 14.38
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet (2006) 13.63
Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet (2010) 10.71
Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet (2007) 9.88
Quantitative comparison of genome-wide DNA methylation mapping technologies. Nat Biotechnol (2010) 5.96
Increasing incidence of colorectal cancer in Asia: implications for screening. Lancet Oncol (2005) 5.13
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Int J Cancer (2008) 2.87
A study of the influence of sex on genome wide methylation. PLoS One (2010) 2.57
Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets. Carcinogenesis (2006) 2.45
DNA methylation markers in colorectal cancer. Cancer Metastasis Rev (2010) 2.40
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci U S A (2010) 2.16
Three DNA methylation epigenotypes in human colorectal cancer. Clin Cancer Res (2009) 2.03
Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer. Genes Chromosomes Cancer (2009) 1.91
The assumptions underlying the analysis of variance. Biometrics (1947) 1.85
DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis. Proc Natl Acad Sci U S A (2009) 1.69
DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines. PLoS One (2010) 1.65
Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas. Int J Cancer (2011) 1.65
DNA hypomethylation in the origin and pathogenesis of human diseases. Cell Mol Life Sci (2009) 1.62
Comparing 3 dietary pattern methods--cluster analysis, factor analysis, and index analysis--With colorectal cancer risk: The NIH-AARP Diet and Health Study. Am J Epidemiol (2009) 1.50
Epigenomic analysis of aberrantly methylated genes in colorectal cancer identifies genes commonly affected by epigenetic alterations. Ann Surg Oncol (2011) 1.50
BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer. Int J Cancer (2006) 1.46
Analysis of a multifactor microarray study using Partek genomics solution. Methods Enzymol (2006) 1.35
Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. Cancer Res (2010) 1.34
Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features. BMC Cancer (2010) 1.32
Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypes. Cancer Sci (2011) 1.20
Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review. Int J Cancer (2011) 1.20
Human DNA repair genes. Environ Mol Mutagen (2001) 1.12
Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer. Am J Pathol (2010) 1.07
Development of a multiplex MethyLight assay for the detection of multigene methylation in human colorectal cancer. Cancer Genet Cytogenet (2010) 1.06
Detection of colorectal neoplasm using promoter methylation of ITGA4, SFRP2, and p16 in stool samples: a preliminary report in Korean patients. Hepatogastroenterology (2010) 1.02
Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis. Oncol Rep (2010) 0.85
Distribution of colon neoplasia in Chinese patients: implications for endoscopic screening strategies. Eur J Gastroenterol Hepatol (2008) 0.84
Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med (2011) 6.89
Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect (2004) 5.19
Arsenic exposure from drinking water, and all-cause and chronic-disease mortalities in Bangladesh (HEALS): a prospective cohort study. Lancet (2010) 5.12
Water manganese exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect (2006) 3.42
Promotion of well-switching to mitigate the current arsenic crisis in Bangladesh. Bull World Health Organ (2002) 3.40
Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort study. BMJ (2011) 3.34
The broad scope of health effects from chronic arsenic exposure: update on a worldwide public health problem. Environ Health Perspect (2013) 2.92
Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants. Int J Epidemiol (2010) 2.91
Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh. Environ Health Perspect (2006) 2.50
Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh. Am J Clin Nutr (2006) 2.41
Multiplex real-time PCR assay for detection of Entamoeba histolytica, Giardia intestinalis, and Cryptosporidium spp. Am J Trop Med Hyg (2007) 2.29
Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in Bangladesh. Cancer Epidemiol Biomarkers Prev (2007) 2.17
Entamoeba moshkovskii infections in children, Bangladesh. Emerg Infect Dis (2003) 2.11
Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review. Environ Health Perspect (2012) 2.05
Reduction in urinary arsenic levels in response to arsenic mitigation efforts in Araihazar, Bangladesh. Environ Health Perspect (2007) 2.03
Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA. Clin Cancer Res (2007) 2.02
Entamoeba histolytica infection in children and protection from subsequent amebiasis. Infect Immun (2006) 1.99
Folate, homocysteine, and arsenic metabolism in arsenic-exposed individuals in Bangladesh. Environ Health Perspect (2005) 1.97
Anopheline vectors and malaria transmission in eastern Afghanistan. Trans R Soc Trop Med Hyg (2003) 1.96
Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults. Am J Clin Nutr (2007) 1.91
Associations of body mass index, smoking, and alcohol consumption with prostate cancer mortality in the Asia Cohort Consortium. Am J Epidemiol (2015) 1.87
Arsenic and manganese exposure and children's intellectual function. Neurotoxicology (2011) 1.82
Genome-wide DNA methylation profiles in hepatocellular carcinoma. Hepatology (2012) 1.81
Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh. Am J Clin Nutr (2005) 1.74
Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk. JAMA (2008) 1.73
Folic acid supplementation lowers blood arsenic. Am J Clin Nutr (2007) 1.70
Giardia assemblage A infection and diarrhea in Bangladesh. J Infect Dis (2005) 1.70
Cancer burden from arsenic in drinking water in Bangladesh. Am J Public Health (2004) 1.68
Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: a population-based, cross-sectional study. Am J Epidemiol (2006) 1.66
Prevalence of arsenic exposure from drinking water and awareness of its health risks in a Bangladeshi population: results from a large population-based study. Environ Health Perspect (2006) 1.65
Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh. PLoS Genet (2012) 1.64
Blood arsenic as a biomarker of arsenic exposure: results from a prospective study. Toxicology (2006) 1.64
Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies. Am J Clin Nutr (2013) 1.61
Validity of a food-frequency questionnaire for a large prospective cohort study in Bangladesh. Br J Nutr (2004) 1.61
Diabetes mellitus and the risk of prostate cancer. Cancer Invest (2002) 1.60
A prospective study of body mass index and mortality in Bangladesh. Int J Epidemiol (2009) 1.59
Body mass index and diabetes in Asia: a cross-sectional pooled analysis of 900,000 individuals in the Asia cohort consortium. PLoS One (2011) 1.55
Arsenic exposure at low-to-moderate levels and skin lesions, arsenic metabolism, neurological functions, and biomarkers for respiratory and cardiovascular diseases: review of recent findings from the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh. Toxicol Appl Pharmacol (2009) 1.51
Design options for molecular epidemiology research within cohort studies. Cancer Epidemiol Biomarkers Prev (2005) 1.49
No association between arsenic exposure from drinking water and diabetes mellitus: a cross-sectional study in Bangladesh. Environ Health Perspect (2010) 1.48
Modification of risk of arsenic-induced skin lesions by sunlight exposure, smoking, and occupational exposures in Bangladesh. Epidemiology (2006) 1.46
High dose genistein aglycone therapy is safe in patients with mucopolysaccharidoses involving the central nervous system. Mol Genet Metab (2013) 1.45
Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesions. Environ Health Perspect (2008) 1.45
Nonmalignant respiratory effects of chronic arsenic exposure from drinking water among never-smokers in Bangladesh. Environ Health Perspect (2008) 1.44
A prospective study of respiratory symptoms associated with chronic arsenic exposure in Bangladesh: findings from the Health Effects of Arsenic Longitudinal Study (HEALS). Thorax (2010) 1.40
Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics (2012) 1.39
Influence of human leukocyte antigen class II alleles on susceptibility to Entamoeba histolytica infection in Bangladeshi children. J Infect Dis (2004) 1.31
Consumption of folate-related nutrients and metabolism of arsenic in Bangladesh. Am J Clin Nutr (2007) 1.31
Further development of the case-only design for assessing gene-environment interaction: evaluation of and adjustment for bias. Int J Epidemiol (2004) 1.29
Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer risk. Cancer Res (2005) 1.29
Association between manganese exposure through drinking water and infant mortality in Bangladesh. Environ Health Perspect (2007) 1.29
Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk. Cancer Res (2008) 1.28
Multiplex real-time PCR assay using Scorpion probes and DNA capture for genotype-specific detection of Giardia lamblia on fecal samples. J Clin Microbiol (2005) 1.25
Evidence for a link between parasite genotype and outcome of infection with Entamoeba histolytica. J Clin Microbiol (2006) 1.24
A prospective study of arsenic exposure, arsenic methylation capacity, and risk of cardiovascular disease in Bangladesh. Environ Health Perspect (2013) 1.24
Real-time PCR detection and speciation of Cryptosporidium infection using Scorpion probes. J Med Microbiol (2006) 1.23
Silencing of glutathione S-transferase P1 by promoter hypermethylation and its relationship to environmental chemical carcinogens in hepatocellular carcinoma. Cancer Lett (2005) 1.23
Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. Cancer Epidemiol Biomarkers Prev (2006) 1.23
Aflatoxin B1 exposure, hepatitis B virus infection, and hepatocellular carcinoma in Taiwan. Cancer Epidemiol Biomarkers Prev (2009) 1.21
A prospective study of arsenic exposure from drinking water and incidence of skin lesions in Bangladesh. Am J Epidemiol (2011) 1.21
Tissue invasion by Entamoeba histolytica: evidence of genetic selection and/or DNA reorganization events in organ tropism. PLoS Negl Trop Dis (2008) 1.18
Association between arsenic exposure and a measure of subclinical sensory neuropathy in Bangladesh. J Occup Environ Med (2005) 1.18
Correlation of interferon-gamma production by peripheral blood mononuclear cells with childhood malnutrition and susceptibility to amebiasis. Am J Trop Med Hyg (2007) 1.17
Nutritional influence on risk of high blood pressure in Bangladesh: a population-based cross-sectional study. Am J Clin Nutr (2006) 1.17
TGFBR1*6A may contribute to hereditary colorectal cancer. J Clin Oncol (2005) 1.16
Evaluation of Entamoeba histolytica antigen and antibody point-of-care tests for the rapid diagnosis of amebiasis. J Clin Microbiol (2006) 1.16
Arsenic exposure and motor function among children in Bangladesh. Environ Health Perspect (2011) 1.15
Association between arsenic exposure from drinking water and plasma levels of soluble cell adhesion molecules. Environ Health Perspect (2007) 1.15
High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma. Mol Carcinog (2002) 1.14
Analyses and interpretation of whole-genome gene expression from formalin-fixed paraffin-embedded tissue: an illustration with breast cancer tissues. BMC Genomics (2010) 1.13
Aflatoxin B1 and polycyclic aromatic hydrocarbon adducts, p53 mutations and p16 methylation in liver tissue and plasma of hepatocellular carcinoma patients. Int J Cancer (2006) 1.12
Urinary and dietary analysis of 18,470 bangladeshis reveal a correlation of rice consumption with arsenic exposure and toxicity. PLoS One (2013) 1.11
Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk. Hum Hered (2010) 1.10
Cancer screening practices of Asian American physicians in New York City. J Immigr Minor Health (2008) 1.09
Betel quid: Its tremor-producing effects in residents of Araihazar, Bangladesh. Mov Disord (2006) 1.09
Socioeconomic status and risk for arsenic-related skin lesions in Bangladesh. Am J Public Health (2007) 1.08
Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls. Int J Cancer (2002) 1.08
Protective effects of B vitamins and antioxidants on the risk of arsenic-related skin lesions in Bangladesh. Environ Health Perspect (2008) 1.07
Arsenic exposure and impaired lung function. Findings from a large population-based prospective cohort study. Am J Respir Crit Care Med (2013) 1.07
Arsenic exposure, dietary patterns, and skin lesion risk in bangladesh: a prospective study. Am J Epidemiol (2010) 1.05
Betel quid chewing in rural Bangladesh: prevalence, predictors and relationship to blood pressure. Int J Epidemiol (2011) 1.05
Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus. Cancer Res (2011) 1.05
Association between arsenic exposure from drinking water and plasma levels of cardiovascular markers. Am J Epidemiol (2012) 1.05