Published in Cell Death Differ on June 24, 2011
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy (2016) 7.05
Autophagy and disease: always two sides to a problem. J Pathol (2011) 1.64
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration. Autophagy (2013) 1.34
Balance between autophagic pathways preserves retinal homeostasis. Aging Cell (2013) 1.23
Novel roles for α-crystallins in retinal function and disease. Prog Retin Eye Res (2012) 1.17
Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model. Cell Death Dis (2012) 1.09
Autophagy in axonal and dendritic degeneration. Trends Neurosci (2013) 1.08
The functional and pathologic relevance of autophagy proteases. J Clin Invest (2015) 1.01
Autophagy in the eye: implications for ocular cell health. Exp Eye Res (2014) 1.00
Autophagy attenuates noise-induced hearing loss by reducing oxidative stress. Antioxid Redox Signal (2015) 0.97
Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration. Cell Death Dis (2013) 0.95
Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection. PLoS Pathog (2014) 0.93
Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells. Autophagy (2014) 0.92
Early otic development depends on autophagy for apoptotic cell clearance and neural differentiation. Cell Death Dis (2012) 0.92
Autophagy in retinal ganglion cells in a rhesus monkey chronic hypertensive glaucoma model. PLoS One (2013) 0.90
Lysosomal membrane permeabilization and autophagy blockade contribute to photoreceptor cell death in a mouse model of retinitis pigmentosa. Cell Death Differ (2014) 0.88
Modulating macroautophagy: a neuronal perspective. Future Med Chem (2012) 0.81
Rapamycin is neuroprotective in a rat chronic hypertensive glaucoma model. PLoS One (2014) 0.79
Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells. BMC Ophthalmol (2014) 0.79
Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene. BMC Cell Biol (2015) 0.78
Axonal protection by short-term hyperglycemia with involvement of autophagy in TNF-induced optic nerve degeneration. Front Cell Neurosci (2015) 0.76
Cell biology: Recycling in sight. Nature (2013) 0.76
Autophagy is essential for hearing in mice. Cell Death Dis (2017) 0.75
Mice deficient in the Vici syndrome gene Epg5 exhibit features of retinitis pigmentosa. Autophagy (2016) 0.75
Why autophagy is good for retinal ganglion cells? Eye (Lond) (2016) 0.75
Tank-Binding Kinase 1 (TBK1) Gene and Open-Angle Glaucomas (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc (2016) 0.75
Involvement of P2X7 receptor in neuronal degeneration triggered by traumatic injury. Sci Rep (2016) 0.75
Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage. PLoS One (2014) 0.75
The Evolving Functions of Autophagy in Ocular Health: A Double-edged Sword. Int J Biol Sci (2016) 0.75
Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids. Cell Death Discov (2017) 0.75
Randomized phase II trial of fulvestrant alone or in combination with bortezomib in hormone receptor-positive metastatic breast cancer resistant to aromatase inhibitors: a New York Cancer Consortium trial. NPJ Breast Cancer (2016) 0.75
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature (2006) 21.40
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell (2003) 17.55
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat Genet (2004) 14.31
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J (2008) 12.89
Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol (2005) 10.27
Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol (2009) 7.96
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science (2008) 6.86
Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev (2010) 6.35
Autophagy gone awry in neurodegenerative diseases. Nat Neurosci (2010) 4.72
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J Neurosci (2008) 4.63
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest (2008) 4.09
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem (2010) 3.84
Regulation of autophagy by ROS: physiology and pathology. Trends Biochem Sci (2010) 3.32
Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nat Neurosci (2008) 2.94
Pathogenic lysosomal depletion in Parkinson's disease. J Neurosci (2010) 2.73
Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric. BMC Neurosci (2006) 2.68
Retracted Characterization of a transformed rat retinal ganglion cell line. Brain Res Mol Brain Res (2001) 2.59
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. Am J Pathol (2008) 2.57
Autophagy in neurodegenerative disease: friend, foe or turncoat? Trends Neurosci (2006) 2.57
Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences. Prog Retin Eye Res (2006) 2.49
Autophagy is essential for mouse sense of balance. J Clin Invest (2010) 1.81
Mouse models of retinal ganglion cell death and glaucoma. Exp Eye Res (2008) 1.79
Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Autophagy (2009) 1.72
Mechanisms of acute axonal degeneration in the optic nerve in vivo. Proc Natl Acad Sci U S A (2010) 1.70
Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases. J Biol Chem (2010) 1.50
Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats. J Neurobiol (1993) 1.48
Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders. Biochim Biophys Acta (2009) 1.48
The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium. Cell Death Differ (2008) 1.41
TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease. J Cell Biol (2009) 1.38
Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration. J Biol Chem (2009) 1.38
Molecular determinants of retinal ganglion cell development, survival, and regeneration. Prog Retin Eye Res (2003) 1.29
Enhancement of autophagic flux after neonatal cerebral hypoxia-ischemia and its region-specific relationship to apoptotic mechanisms. Am J Pathol (2009) 1.23
Intraocular pressure elevation induces mitochondrial fission and triggers OPA1 release in glaucomatous optic nerve. Invest Ophthalmol Vis Sci (2008) 1.20
Activation of autophagy in retinal ganglion cells. J Neurosci Res (2008) 1.00
Schwann cells promote the survival of rat retinal ganglion cells after optic nerve section. Proc Natl Acad Sci U S A (1990) 0.88
The quantitative genetic basis of offspring solicitation and parental response in a passerine bird with biparental care. Proc Biol Sci (2000) 2.10
Functional and structural modifications during retinal degeneration in the rd10 mouse. Neuroscience (2008) 1.53
Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling. Cell Death Differ (2013) 1.49
BH3 mimetics activate multiple pro-autophagic pathways. Oncogene (2011) 1.41
The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium. Cell Death Differ (2008) 1.41
Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization. Cell Death Differ (2002) 1.23
The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway. Cell Death Differ (2002) 1.15
Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma. Apoptosis (2004) 1.03
Proximate mechanisms of variation in the carotenoid-based plumage coloration of nestling great tits (Parus major L.). J Evol Biol (2003) 1.00
Obesity and postmenopausal bone loss: the influence of obesity on vertebral density and bone turnover in postmenopausal women. Bone (1987) 0.97
Mother-offspring competition promotes colonization success. Proc Natl Acad Sci U S A (2007) 0.95
Interferon alfa subtypes and levels of type I interferons in the liver and peripheral mononuclear cells in patients with chronic hepatitis C and controls. Hepatology (1999) 0.94
Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors. Cell Death Differ (2008) 0.93
Experimental enhancement of corticosterone levels positively affects subsequent male survival. Horm Behav (2005) 0.93
Lifetime and intergenerational fitness consequences of harmful male interactions for female lizards. Ecology (2008) 0.91
Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization. Apoptosis (2003) 0.87
Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1. Apoptosis (2004) 0.83
Expression of interferon-alpha subtypes in peripheral mononuclear cells from patients with chronic hepatitis C: a role for interferon-alpha5. J Viral Hepat (2001) 0.83
Age-related functional and structural retinal modifications in the Igf1-/- null mouse. Neurobiol Dis (2012) 0.83
Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo. Apoptosis (2002) 0.82
[Alterations in nocturnal melatonin secretion in patients with optic neuropathies]. Arch Soc Esp Oftalmol (2009) 0.81
Female common lizards (Lacerta vivipara) do not adjust their sex-biased investment in relation to the adult sex ratio. J Evol Biol (2005) 0.81
Environmentally induced changes in carotenoid-based coloration of female lizards: a comment on Vercken et al. J Evol Biol (2008) 0.80
Corticosterone regulates multiple colour traits in Lacerta [Zootoca] vivipara males. J Evol Biol (2013) 0.78
Effects of dietary L-arginine supplementation on serum lipids and intestinal enzyme activities in diabetic rats. J Physiol Biochem (2004) 0.76
Gastric heterotopic mucosa in the rectum with Helicobacter pylori-like organisms: a rare cause of rectal bleeding. Int J Colorectal Dis (1993) 0.76
Detection of Genomic Polymorphism in Plasmodium falciparum using an arbitrarily primed PCR assay. J Eukaryot Microbiol (1997) 0.75
[Anatomic breast implants in aesthetic and reconstructive surgery: report of 135 cases]. Ann Chir Plast Esthet (2007) 0.75
[A well-tolerated hypokalemia ... or the justification for preoperative biological tests]. Presse Med (1990) 0.75
Independent sources of condition dependency and multiple pathways determine a composite trait: lessons from carotenoid-based plumage colouration. J Evol Biol (2013) 0.75
In vitro dynamics of chromatin organization and migration. Cell Biol Toxicol (1996) 0.75