Published in Fitoterapia on June 25, 2011
The application of HPLC and microprobe NMR spectroscopy in the identification of metabolites in complex biological matrices. Anal Bioanal Chem (2015) 0.78
Structure Elucidation of the Metabolites of 2', 3', 5'-Tri-O-Acetyl-N6-(3-Hydroxyphenyl) Adenosine in Rat Urine by HPLC-DAD, ESI-MS and Off-Line Microprobe NMR. PLoS One (2015) 0.77
Activities of psilostachyin A and cynaropicrin against Trypanosoma cruzi in vitro and in vivo. Antimicrob Agents Chemother (2013) 1.47
Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza. Planta Med (2011) 1.46
Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies. Fluids Barriers CNS (2013) 1.15
Marine actinomycetes as a source of novel secondary metabolites. Antonie Van Leeuwenhoek (2005) 1.12
Plants traditionally used in age related brain disorders--a survey of ethnobotanical literature. J Ethnopharmacol (2007) 1.05
Farinosones A-C, neurotrophic alkaloidal metabolites from the entomogenous deuteromycete Paecilomyces farinosus. J Nat Prod (2004) 1.02
Morinda citrifolia (Noni) fruit--phytochemistry, pharmacology, safety. Planta Med (2007) 1.01
Novel tetramic acids and pyridone alkaloids, militarinones B, C, and D, from the insect pathogenic fungus Paecilomyces militaris. J Nat Prod (2003) 1.00
Antitrypanosomal sesquiterpene lactones from Saussurea costus. Fitoterapia (2011) 0.96
Cynaropicrin: the first plant natural product with in vivo activity against Trypanosoma brucei. Planta Med (2012) 0.95
Malaria in the Renaissance: remedies from European herbals from the 16th and 17th century. J Ethnopharmacol (2010) 0.95
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes. Fitoterapia (2010) 0.94
Medicinal herbs for the treatment of rheumatic disorders--a survey of European herbals from the 16th and 17th century. J Ethnopharmacol (2008) 0.93
Pharmacokinetics of α-mangostin in rats after intravenous and oral application. Mol Nutr Food Res (2011) 0.93
Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7. BMC Pharmacol (2007) 0.93
Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays. Nat Prod Rep (2013) 0.93
Triterpenoids with rare carbon skeletons from Salvia hydrangea: antiprotozoal activity and absolute configurations. J Nat Prod (2011) 0.90
HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site. J Nat Prod (2010) 0.89
A simple method for preparation of D-rhamnose. Carbohydr Res (2003) 0.89
Inhibitory activity of tryptanthrin on prostaglandin and leukotriene synthesis. Planta Med (2002) 0.88
Rapid analysis of nucleotide-activated sugars by high-performance liquid chromatography coupled with diode-array detection, electrospray ionization mass spectrometry and nuclear magnetic resonance. J Chromatogr A (2004) 0.87
Drug discovery and development with plant-derived compounds. Prog Drug Res (2008) 0.87
Traditional use of herbal remedies in livestock by farmers in 3 Swiss cantons (Aargau, Zurich, Schaffhausen). Forsch Komplementmed (2012) 0.87
Frigocyclinone, a novel angucyclinone antibiotic produced by a Streptomyces griseus strain from Antarctica. J Antibiot (Tokyo) (2005) 0.86
HPLC-based activity profiling of Salvia miltiorrhiza for MAO A and iNOS inhibitory activities. Planta Med (2004) 0.86
Ethnoveterinary herbal remedies used by farmers in four north-eastern Swiss cantons (St. Gallen, Thurgau, Appenzell Innerrhoden and Appenzell Ausserrhoden). J Ethnobiol Ethnomed (2014) 0.86
Anti-inflammatory and antiallergic activity in vivo of lipophilic Isatis tinctoria extracts and tryptanthrin. Planta Med (2006) 0.86
Abietane diterpenoids from Salvia sahendica--antiprotozoal activity and determination of their absolute configurations. Planta Med (2013) 0.85
(+)-N-Deoxymilitarinone A, a neuritogenic pyridone alkaloid from the insect pathogenic fungus Paecilomyces farinosus. J Nat Prod (2006) 0.85
Promotion of cell death or neurite outgrowth in PC-12 and N2a cells by the fungal alkaloid militarinone A depends on basal expression of p53. Apoptosis (2008) 0.85
HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root). Mol Divers (2011) 0.85
Seasonal changes and effect of harvest on glucosinolates in Isatis leaves. Planta Med (2008) 0.85
New coumarin-hemiterpene ether glucosides and a structurally related phenylpropanoic acid derivative from Artemisia armeniaca. Nat Prod Commun (2010) 0.85
Treatment of organic livestock with medicinal plants: a systematic review of European ethnoveterinary research. Forsch Komplementmed (2014) 0.85
Radical scavengers from the entomogenous deuteromycete Beauveria amorpha. Planta Med (2002) 0.84
Pharmacokinetics of valerenic acid in rats after intravenous and oral administrations. Planta Med (2012) 0.84
High-resolution crystal structure of a lasso Peptide. ChemMedChem (2010) 0.84
Extraction and analysis of intact glucosinolates--a validated pressurized liquid extraction/liquid chromatography-mass spectrometry protocol for Isatis tinctoria, and qualitative analysis of other cruciferous plants. J Chromatogr A (2007) 0.83
HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes. Planta Med (2008) 0.83
Renaissance remedies: Antiplasmodial protostane triterpenoids from Alisma plantago-aquatica L. (Alismataceae). J Ethnopharmacol (2011) 0.83
Regulation of secretases by all-trans-retinoic acid. FEBS J (2009) 0.83
[Between empiricism and evidence - ( re ) activation of veterinary phytotherapy]. Forsch Komplementmed (2014) 0.83
Bisabololoxide derivatives from Artemisia persica, and determination of their absolute configurations by ECD. Phytochemistry (2012) 0.82
Ultraviolet a induces generation of squalene monohydroperoxide isomers in human sebum and skin surface lipids in vitro and in vivo. J Invest Dermatol (2003) 0.82
Total synthesis and neuritotrophic activity of farinosone C and derivatives. Org Lett (2009) 0.82
Militarinone A, a neurotrophic pyridone alkaloid from Paecilomyces militaris. Org Lett (2002) 0.82
HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium. J Nat Prod (2010) 0.82
Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure. PLoS One (2010) 0.82
Flash chromatography on cartridges for the separation of plant extracts: rules for the selection of chromatographic conditions and comparison with medium pressure liquid chromatography. Fitoterapia (2010) 0.82
A protocol for HPLC-based activity profiling for natural products with activities against tropical parasites. Nat Prod Commun (2009) 0.81
Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids. J Agric Food Chem (2011) 0.81
Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling. J Nat Prod (2011) 0.80
Epilepsy in the Renaissance: a survey of remedies from 16th and 17th century German herbals. J Ethnopharmacol (2012) 0.80
A comprehensive metabolite profiling of Isatis tinctoria leaf extracts. Phytochemistry (2009) 0.80
GABAA receptor modulation by piperine and a non-TRPV1 activating derivative. Biochem Pharmacol (2013) 0.80
Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei. Bioorg Med Chem (2013) 0.80
Identification of TLC markers and quantification by HPLC-MS of various constituents in noni fruit powder and commercial noni-derived products. J Agric Food Chem (2007) 0.80
Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose oil. J Agric Food Chem (2004) 0.79
Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants. Sci Pharm (2011) 0.79
Separation and detection of all phosphoinositide isomers by ESI-MS. J Pharm Biomed Anal (2010) 0.79
Analysis of aspartyl peptide degradation products by high-performance liquid chromatography and high-performance liquid chromatography-mass spectrometry. J Chromatogr A (2004) 0.79
Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice. J Nat Prod (2011) 0.78
Quantitative determination of the dual COX-2/5-LOX inhibitor tryptanthrin in Isatis tinctoria by ESI-LC-MS. Planta Med (2002) 0.78
Antiplasmodial lanostanes from the Ganoderma lucidum mushroom. J Nat Prod (2010) 0.78
Manoyloxide Sesterterpenoids from Salvia mirzayanii. J Nat Prod (2014) 0.78
Antitrypanosomal triterpenoid with an ε-lactone E-ring from Salvia urmiensis. J Nat Prod (2013) 0.78
Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations. Phytochemistry (2011) 0.78
Metabolite profiling of the leaves of the Brazilian folk medicine Sideroxylon obtusifolium. Planta Med (2012) 0.78
Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae). BMC Complement Altern Med (2013) 0.77
Library-based discovery of DYRK1A/CLK1 inhibitors from natural product extracts. Planta Med (2012) 0.77
Antiprotozoal screening of 60 South African plants, and the identification of the antitrypanosomal germacranolides schkuhrin I and II. Planta Med (2013) 0.77
Hydrangenone, a new isoprenoid with an unprecedented skeleton from Salvia hydrangea. Org Lett (2011) 0.77
Glucosinolate pattern in Isatis tinctoria and I. indigotica seeds. Planta Med (2008) 0.77
The elusive indigo precursors in woad (Isatis tinctoria L.)--identification of the major indigo precursor, isatan A, and a structure revision of isatan B. Chem Biodivers (2004) 0.77
HERG channel inhibitors in extracts of Coptidis rhizoma. Planta Med (2011) 0.77
Composition of Indigo naturalis. Planta Med (2009) 0.77
The content of indigo precursors in Isatis tinctoria leaves--a comparative study of selected accessions and post-harvest treatments. Phytochemistry (2004) 0.76
Library-based discovery and characterization of daphnane diterpenes as potent and selective HIV inhibitors in Daphne gnidium. J Nat Prod (2011) 0.76
Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives. J Med Chem (2014) 0.76
In vitro screening of traditional South African malaria remedies against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum. Planta Med (2011) 0.76
Quantification of active principles and pigments in leaf extracts of Isatis tinctoria by HPLC/UV/MS. Planta Med (2007) 0.76
A comparative study on the skin penetration of pure tryptanthrin and tryptanthrin in Isatis tinctoria extract by dermal microdialysis coupled with isotope dilution ESI-LC-MS. Planta Med (2003) 0.76
Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways. FEBS Lett (2004) 0.76
Antiprotozoal isoflavan quinones from Abrus precatorius ssp. africanus. Planta Med (2013) 0.76
Are extraction methods in quantitative assays of pharmacopoeia monographs exhaustive? A comparison with pressurized liquid extraction. Planta Med (2006) 0.76
Development and full validation of an UPLC-MS/MS method for the determination of an anti-allergic indolinone derivative in rat plasma, and application to a preliminary pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.76
Case study of the Swiss flora for prior phytochemical and biological investigations. J Nat Prod (2013) 0.76
Two new flavonol glycosides and a metabolite profile of Bryophyllum pinnatum, a phytotherapeutic used in obstetrics and gynaecology. Planta Med (2013) 0.76
HPLC-based activity profiling for GABAA receptor modulators in Adenocarpus cincinnatus. J Nat Prod (2014) 0.76
Telemetry as a tool to measure sedative effects of a valerian root extract and its single constituents in mice. Planta Med (2010) 0.76
Comment on Comparison of protective effects between cultured Cordyceps militaris and natural Cordyceps sinensis against oxidative damage. J Agric Food Chem (2007) 0.76