PubRank

B S Schaffhausen

Author PubWeight™ 55.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Purification and characterization of phosphoinositide 3-kinase from rat liver. J Biol Chem 1990 4.75
2 Tumor antigen(s) in cell productively infected by wild-type polyoma virus and mutant NG-18. Proc Natl Acad Sci U S A 1978 4.64
3 Regulation of protein kinase C zeta by PI 3-kinase and PDK-1. Curr Biol 1998 4.13
4 Phosphorylation of polyoma T antigens. Cell 1979 3.94
5 Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformation. Proc Natl Acad Sci U S A 1982 3.12
6 Deficiency in histone acetylation in nontransforming host range mutants of polyoma virus. Proc Natl Acad Sci U S A 1976 2.37
7 Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production. J Virol 1986 2.27
8 DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication. Genes Dev 1997 2.06
9 Polyoma virus middle T antigen: relationship to cell membranes and apparent lack of ATP-binding activity. Mol Cell Biol 1982 1.87
10 Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen. Proc Natl Acad Sci U S A 1984 1.71
11 Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen. Proc Natl Acad Sci U S A 1994 1.55
12 Characterization of pp85, a target of oncogenes and growth factor receptors. Mol Cell Biol 1990 1.51
13 Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase. J Biol Chem 1994 1.47
14 Characterization of middle T antigen expressed by using an adenovirus expression system. J Virol 1987 1.25
15 Tyrosine phosphorylation is a signal for the trafficking of pp85, an 85-kDa phosphorylated polypeptide associated with phosphatidylinositol kinase activity. Proc Natl Acad Sci U S A 1990 1.24
16 Association of Polyomavirus middle tumor antigen with phospholipase C-gamma 1. J Biol Chem 1995 1.23
17 A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity. J Virol 1990 1.16
18 Abundant expression of polyomavirus middle T antigen and dihydrofolate reductase in an adenovirus recombinant. J Virol 1987 1.15
19 Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase. J Virol 1992 1.12
20 Large-scale production of polyoma middle T antigen by using genetically engineered tumors. Mol Cell Biol 1985 1.03
21 Protein domains connect cell cycle stimulation directly to initiation of DNA replication. Proc Natl Acad Sci U S A 1994 1.02
22 Mutations in the juxtamembrane region of the insulin receptor impair activation of phosphatidylinositol 3-kinase by insulin. Mol Endocrinol 1991 1.02
23 Residual transforming activity of PY1178T, a mutant lacking the principal in vitro tyrosine phosphorylation site, is not affected by removal of the secondary tyrosine phosphorylation site at residue 322. Virology 1985 0.93
24 The hr-t gene of polyoma virus. Cold Spring Harb Symp Quant Biol 1980 0.93
25 Characterization of an immortalizing N-terminal domain of polyomavirus large T antigen. J Virol 1994 0.92
26 Zinc-binding and protein-protein interactions mediated by the polyomavirus large T antigen zinc finger. J Virol 1995 0.89
27 Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteins. J Virol 1998 0.87
28 Phosphorylation sites in polyomavirus large T antigen that regulate its function in viral, but not cellular, DNA synthesis. J Virol 1997 0.86
29 Polyoma T (tumor) antigen species in abortively and stably transformed cells. J Supramol Struct 1979 0.86
30 Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members. J Virol 1996 0.84
31 Transformation by polyoma ts-a mutants. I. Characterization of the transformed phenotype. Virology 1985 0.83
32 Immunization against the polyoma tumor-specific transplantation antigen (TSTA) with polyoma T-antigens. Int J Cancer 1988 0.81
33 Polyomavirus large T can support DNA replication in human cells. Virology 1998 0.78
34 Oncogenes and phosphatidylinositol turnover. Ann N Y Acad Sci 1986 0.77
35 Phosphatidylinositol kinases and cell transformation. Symp Fundam Cancer Res 1986 0.75