Published in Pharmacol Res on July 01, 2011
Chronic antiplatelet therapy is not associated with alterations in the presentation, outcome, or host response biomarkers during sepsis: a propensity-matched analysis. Intensive Care Med (2016) 1.43
Genome-wide expression profiling in pediatric septic shock. Pediatr Res (2013) 1.39
The 372 T/C genetic polymorphism of TIMP-1 is associated with serum levels of TIMP-1 and survival in patients with severe sepsis. Crit Care (2013) 1.05
Soluble adhesion molecules as markers for sepsis and the potential pathophysiological discrepancy in neonates, children and adults. Crit Care (2014) 1.05
Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis. Ann Rheum Dis (2012) 1.01
The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology. Expert Rev Anti Infect Ther (2014) 0.98
Association of sepsis-related mortality with early increase of TIMP-1/MMP-9 ratio. PLoS One (2014) 0.93
Pharmacological targets in the renal peritubular microenvironment: implications for therapy for sepsis-induced acute kidney injury. Pharmacol Ther (2012) 0.93
Comparison of localized versus systemic levels of Matrix metalloproteinases (MMPs), its tissue inhibitors (TIMPs) and cytokines in tuberculous and non-tuberculous pleuritis patients. Hum Immunol (2012) 0.91
Role of plasma matrix-metalloproteases (MMPs) and their polymorphisms (SNPs) in sepsis development and outcome in ICU patients. Sci Rep (2014) 0.90
TIMP-1 gene polymorphism: are genetics able to predict outcome of septic patients? Crit Care (2013) 0.89
MMP-8 deficiency increases TLR/RAGE ligands S100A8 and S100A9 and exacerbates lung inflammation during endotoxemia. PLoS One (2012) 0.83
Serum metalloproteinases 2 and 9 as predictors of gait status, pressure ulcer and mortality after hip fracture. PLoS One (2013) 0.78
TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice. Haematologica (2015) 0.78
Biomarkers in Pediatric ARDS: Future Directions. Front Pediatr (2016) 0.75
Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8. Mol Ther (2016) 0.75
TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model. PLoS One (2017) 0.75
Is Matrix Metalloproteinase-8 Activity in the Mucosal Barrier a Requirement for Leakage of Cecal Material in Peritonitis? Crit Care Med (2016) 0.75
Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo. Mediators Inflamm (2015) 0.75
Subclinical inflammation associated with prolonged TIMP-1 upregulation and arterial stiffness after gestational diabetes mellitus: a hospital-based cohort study. Cardiovasc Diabetol (2017) 0.75
Matrix metalloproteinases -8 and -9 and tissue inhibitor of metalloproteinase-1 in burn patients. A prospective observational study. PLoS One (2015) 0.75
Association of Matrix Metalloproteinases -7, -8 and -9 and TIMP -1 with Disease Severity in Acute Pancreatitis. A Cohort Study. PLoS One (2016) 0.75
Endotoxemia shifts neutrophils with TIMP-free gelatinase B/ MMP-9 from bone marrow to periphery and induces systematic upregulation of TIMP-1. Haematologica (2017) 0.75
The Novel HDAC8 Inhibitor WK2-16 Attenuates Lipopolysaccharide-Activated Matrix Metalloproteinase-9 Expression in Human Monocytic Cells and Improves Hypercytokinemia In Vivo. Int J Mol Sci (2017) 0.75
Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med (2009) 10.60
Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome. JAMA (2009) 9.47
Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med (2014) 6.93
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA (2003) 4.54
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA (2012) 4.13
Long-term survival, quality of life, and quality-adjusted life-years among critically ill elderly patients. Crit Care Med (2006) 3.05
Survival and quality of life of patients requiring acute renal replacement therapy. Intensive Care Med (2005) 3.05
A multibiomarker-based outcome risk stratification model for adult septic shock*. Crit Care Med (2014) 2.94
Acute renal failure after cardiac surgery: evaluation of the RIFLE classification. Ann Thorac Surg (2006) 2.77
Serum matrix metalloproteinase-8 concentrations are associated with cardiovascular outcome in men. Arterioscler Thromb Vasc Biol (2007) 2.74
Predictive value of N-terminal pro-brain natriuretic peptide in severe sepsis and septic shock. Crit Care Med (2007) 2.44
Long-term outcome and quality-adjusted life years after severe sepsis. Crit Care Med (2009) 2.41
The effect of subantimicrobial-dose-doxycycline periodontal therapy on serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial. J Am Dent Assoc (2011) 2.20
Acute respiratory failure in intensive care units. FINNALI: a prospective cohort study. Intensive Care Med (2009) 2.14
Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin. Arch Oral Biol (2006) 2.09
Gingival crevicular fluid and serum matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 levels in renal transplant patients undergoing different immunosuppressive therapy. J Clin Periodontol (2008) 2.05
Multiple organ dysfunction associated with severe acute pancreatitis. Crit Care Med (2002) 2.01
Hemodynamic variables related to outcome in septic shock. Intensive Care Med (2005) 1.95
Strict versus moderate glucose control after resuscitation from ventricular fibrillation. Intensive Care Med (2007) 1.87
Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Crit Care (2009) 1.87
Incidence, treatment, and outcome of severe sepsis in ICU-treated adults in Finland: the Finnsepsis study. Intensive Care Med (2007) 1.85
Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study. Intensive Care Med (2013) 1.80
Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study. Intensive Care Med (2013) 1.77
Mixed venous oxygen saturation cannot be estimated by central venous oxygen saturation in septic shock. Intensive Care Med (2006) 1.73
Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity. Mol Cancer Res (2006) 1.69
Serum neuron-specific enolase and S-100B protein in cardiac arrest patients treated with hypothermia. Stroke (2003) 1.67
Predictive value of procalcitonin decrease in patients with severe sepsis: a prospective observational study. Crit Care (2010) 1.67
A single adrenocorticotropic hormone stimulation test does not reveal adrenal insufficiency in septic shock. Anesth Analg (2005) 1.64
Arterial blood gas tensions after resuscitation from out-of-hospital cardiac arrest: associations with long-term neurologic outcome. Crit Care Med (2014) 1.59
Relation of the Sequential Organ Failure Assessment score to morbidity and mortality after cardiac surgery. Ann Thorac Surg (2006) 1.58
Fluid overload is associated with an increased risk for 90-day mortality in critically ill patients with renal replacement therapy: data from the prospective FINNAKI study. Crit Care (2012) 1.55
The attributable mortality of acute kidney injury: a sequentially matched analysis*. Crit Care Med (2014) 1.52
Cardiac troponin T levels for risk stratification in pediatric open heart surgery. Ann Thorac Surg (2006) 1.50
Prognostic value of chromogranin A in severe sepsis: data from the FINNSEPSIS study. Intensive Care Med (2012) 1.48
Safe long-distance interhospital ground transfer of critically ill patients with acute severe unstable respiratory and circulatory failure. Intensive Care Med (2002) 1.48
Levosimendan as a rescue drug in experimental propranolol-induced myocardial depression: a randomized study. Ann Emerg Med (2009) 1.46
Emdogain in carcinogenesis: a systematic review of in vitro studies. J Oral Sci (2010) 1.41
Jejunal luminal microdialysate lactate in cardiac tamponade--effect of low systemic blood flow on gut mucosa. Intensive Care Med (2002) 1.39
Increased splanchnic oxygen extraction because of routine nursing procedures. Crit Care Med (2009) 1.38
Cell-free plasma DNA as a predictor of outcome in severe sepsis and septic shock. Clin Chem (2008) 1.37
The effects of ICU admission and discharge times on mortality in Finland. Intensive Care Med (2003) 1.31
Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases. Exp Cell Res (2005) 1.30
Matrix metalloproteinases and their tissue inhibitors in aqueous humor of patients with primary open-angle glaucoma, exfoliation syndrome, and exfoliation glaucoma. J Glaucoma (2005) 1.25
Clinical changes in periodontium during pregnancy and post-partum. J Clin Periodontol (2008) 1.23
Junctional ectopic tachycardia after surgery for congenital heart disease: incidence, risk factors and outcome. Eur J Cardiothorac Surg (2011) 1.23
Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration. Biochem Biophys Res Commun (2003) 1.23
The effect of subgingival controlled-release delivery of chlorhexidine chip on clinical parameters and matrix metalloproteinase-8 levels in gingival crevicular fluid. J Periodontol (2002) 1.22
Subantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women. J Periodontol (2008) 1.21
Comparison of 2 acute renal failure severity scores to general scoring systems in the critically ill. Am J Kidney Dis (2006) 1.19
Salivary biomarkers of oral health: a cross-sectional study. J Clin Periodontol (2012) 1.19
Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13. J Biol Chem (2003) 1.18
Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis. J Periodontal Res (2003) 1.16
Predictive power of serum NSE and OHCA score regarding 6-month neurologic outcome after out-of-hospital ventricular fibrillation and therapeutic hypothermia. Resuscitation (2008) 1.16
Characteristics of discrepancies between clinical and autopsy diagnoses in the intensive care unit: a 5-year review. Intensive Care Med (2002) 1.15
Matrix metalloproteinases -8, -9 and -12 in smokers and patients with stage 0 COPD. Int J Chron Obstruct Pulmon Dis (2007) 1.15
HMGB1 as a predictor of organ dysfunction and outcome in patients with severe sepsis. Intensive Care Med (2008) 1.15
Circulating high sensitivity troponin T in severe sepsis and septic shock: distribution, associated factors, and relation to outcome. Intensive Care Med (2010) 1.14
Salivary biomarkers for detection of systemic diseases. PLoS One (2013) 1.13
Salivary MMP-8, TIMP-1, and ICTP as markers of advanced periodontitis. J Clin Periodontol (2010) 1.12