| Rank | Title | Journal | Year | PubWeight™‹?› |
|---|---|---|---|---|
| 1 | Pharmacokinetics of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: the role of alpha-1-acid glycoprotein binding. | Clin Cancer Res | 2011 | 2.12 |
| 2 | Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). | J Med Chem | 2012 | 1.27 |
| 3 | Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors. | Clin Cancer Res | 2011 | 1.25 |
| 4 | A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties. | Bioorg Med Chem Lett | 2008 | 0.83 |
| 5 | Modifications of the isonipecotic acid fragment of SNS-032: analogs with improved permeability and lower efflux ratio. | Bioorg Med Chem Lett | 2008 | 0.77 |