Published in PLoS One on July 08, 2011
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Bacteriocins - a viable alternative to antibiotics? Nat Rev Microbiol (2012) 2.76
Radical S-adenosylmethionine enzymes. Chem Rev (2014) 1.64
The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A. Nat Chem Biol (2012) 1.39
Metagenomics and novel gene discovery: promise and potential for novel therapeutics. Virulence (2013) 1.03
Bacteriocins of lactic acid bacteria: extending the family. Appl Microbiol Biotechnol (2016) 0.96
Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis. ACS Chem Biol (2013) 0.94
Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria. BMC Genomics (2014) 0.93
Biochemical and Spectroscopic Characterization of a Radical S-Adenosyl-l-methionine Enzyme Involved in the Formation of a Peptide Thioether Cross-Link. Biochemistry (2016) 0.92
Genome mining for methanobactins. BMC Biol (2013) 0.90
The Radical S-Adenosyl-l-methionine Enzyme MftC Catalyzes an Oxidative Decarboxylation of the C-Terminus of the MftA Peptide. Biochemistry (2016) 0.85
Radical SAM-mediated methylation reactions. Curr Opin Chem Biol (2013) 0.85
Circular bacteriocins: biosynthesis and mode of action. Appl Environ Microbiol (2014) 0.83
In silico identification of bacteriocin gene clusters in the gastrointestinal tract, based on the Human Microbiome Project's reference genome database. BMC Microbiol (2015) 0.82
Functional genetic analysis of the GarML gene cluster in Lactococcus garvieae DCC43 gives new insights into circular bacteriocin biosynthesis. J Bacteriol (2013) 0.81
Emerging concepts promising new horizons for marine biodiscovery and synthetic biology. Mar Drugs (2015) 0.80
Distribution and Genetic Diversity of Bacteriocin Gene Clusters in Rumen Microbial Genomes. Appl Environ Microbiol (2015) 0.78
Solution structure of acidocin B, a circular bacteriocin produced by Lactobacillus acidophilus M46. Appl Environ Microbiol (2015) 0.77
Three Novel Lantibiotics, Ticins A1, A3, and A4, Have Extremely Stable Properties and Are Promising Food Biopreservatives. Appl Environ Microbiol (2015) 0.76
Bioengineering: a bacteriocin perspective. Bioengineered (2012) 0.76
A mutant ('lab strain') of the hyperthermophilic archaeon Pyrococcus furiosus, lacking flagella, has unusual growth physiology. Extremophiles (2014) 0.76
Genomic Diversity of Enterotoxigenic Strains of Bacteroides fragilis. PLoS One (2016) 0.75
Advances in the Microbiome: Applications to Clostridium difficile Infection. J Clin Med (2016) 0.75
Genome analysis reveals insights of the endophytic Bacillus toyonensis BAC3151 as a potentially novel agent for biocontrol of plant pathogens. World J Microbiol Biotechnol (2017) 0.75
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics (2004) 50.89
Artemis: sequence visualization and annotation. Bioinformatics (2000) 46.68
Comparative metagenomics of microbial communities. Science (2005) 25.88
The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific. PLoS Biol (2007) 23.58
A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med (2005) 16.59
Bacillus thuringiensis and its pesticidal crystal proteins. Microbiol Mol Biol Rev (1998) 13.47
Dendroscope: An interactive viewer for large phylogenetic trees. BMC Bioinformatics (2007) 11.03
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02
CAMERA: a community resource for metagenomics. PLoS Biol (2007) 6.49
Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods. Nucleic Acids Res (2001) 6.49
Increase in Clostridium difficile-related mortality rates, United States, 1999-2004. Emerg Infect Dis (2007) 4.61
Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiology (2010) 3.68
Bacteroides: the good, the bad, and the nitty-gritty. Clin Microbiol Rev (2007) 3.61
Biosynthesis of bacteriocins in lactic acid bacteria. Antonie Van Leeuwenhoek (1996) 3.46
Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A (2008) 3.20
Bacillus cereus and its food poisoning toxins. FEMS Microbiol Lett (1997) 3.00
S-Adenosylmethionine-dependent methylation in Saccharomyces cerevisiae. Identification of a novel protein arginine methyltransferase. J Biol Chem (1999) 2.54
Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proc Natl Acad Sci U S A (2006) 2.19
Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon. Proc Natl Acad Sci U S A (2010) 2.11
Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile. Proc Natl Acad Sci U S A (2010) 1.89
Common mechanisms of target cell recognition and immunity for class II bacteriocins. Proc Natl Acad Sci U S A (2007) 1.81
Assessing diversity and biogeography of aerobic anoxygenic phototrophic bacteria in surface waters of the Atlantic and Pacific Oceans using the Global Ocean Sampling expedition metagenomes. Environ Microbiol (2007) 1.80
Ruminococcin A, a new lantibiotic produced by a Ruminococcus gnavus strain isolated from human feces. Appl Environ Microbiol (2001) 1.69
Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins. Appl Environ Microbiol (2009) 1.68
Metabolism of glucose and cellobiose by cellulolytic mesophilic Clostridium sp. strain H10. Appl Environ Microbiol (1983) 1.63
Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes. PLoS Pathog (2008) 1.53
Structure of subtilosin A, a cyclic antimicrobial peptide from Bacillus subtilis with unusual sulfur to alpha-carbon cross-links: formation and reduction of alpha-thio-alpha-amino acid derivatives. Biochemistry (2004) 1.50
Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family. BMC Biol (2010) 1.49
Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42. J Bacteriol (2010) 1.47
Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria. Nucleic Acids Res (2009) 1.38
Salivaricin A2 and the novel lantibiotic salivaricin B are encoded at adjacent loci on a 190-kilobase transmissible megaplasmid in the oral probiotic strain Streptococcus salivarius K12. Appl Environ Microbiol (2006) 1.36
Multiple activities in lantibiotics--models for the design of novel antibiotics? Curr Pharm Des (2002) 1.32
Potential of bacteriocin-producing lactic acid bacteria for improvements in food safety and quality. Biochimie (2002) 1.30
Two-peptide lantibiotics: a medical perspective. Mini Rev Med Chem (2007) 1.26
Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem (2010) 1.25
Carbon and electron flow in Clostridium cellulolyticum grown in chemostat culture on synthetic medium. J Bacteriol (1999) 1.25
Caldicellulosiruptor kristjanssonii sp. nov., a cellulolytic, extremely thermophilic, anaerobic bacterium. Int J Syst Bacteriol (1999) 1.24
Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125. FEMS Microbiol Lett (2007) 1.21
Mutational analysis of the sbo-alb locus of Bacillus subtilis: identification of genes required for subtilosin production and immunity. J Bacteriol (2000) 1.15
Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13. PLoS One (2009) 1.14
Two different lantibiotic-like peptides originate from the ericin gene cluster of Bacillus subtilis A1/3. J Bacteriol (2002) 1.13
Peptide antibiotic subtilin is synthesized via precursor proteins. Biochem Biophys Res Commun (1983) 1.05
In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria. BMC Genomics (2010) 1.04
Thermoanaerobacter mathranii sp. nov., an ethanol-producing, extremely thermophilic anaerobic bacterium from a hot spring in Iceland. Arch Microbiol (1997) 1.03
Petrotoga mobilis sp. nov., from a North Sea oil-production well. Int J Syst Bacteriol (1998) 1.01
Molecular and genetic characterization of propionicin F, a bacteriocin from Propionibacterium freudenreichii. Appl Environ Microbiol (2004) 0.98
Cloning, nucleotide sequence, and expression of the gene encoding the bacteriocin boticin B from Clostridium botulinum strain 213B. Appl Environ Microbiol (2000) 0.95
Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics. Chembiochem (2009) 0.92
Characterization of bacteriocin 28 produced by Clostridium perfringens. Can J Microbiol (1982) 0.80
Gut microbiota composition correlates with diet and health in the elderly. Nature (2012) 6.94
Bacteriocins: developing innate immunity for food. Nat Rev Microbiol (2005) 5.77
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci U S A (2010) 5.02
Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine. PLoS One (2009) 4.93
M-Coffee: combining multiple sequence alignment methods with T-Coffee. Nucleic Acids Res (2006) 4.53
Comparison of two next-generation sequencing technologies for resolving highly complex microbiota composition using tandem variable 16S rRNA gene regions. Nucleic Acids Res (2010) 4.17
The interaction between bacteria and bile. FEMS Microbiol Rev (2005) 3.86
Surviving the acid test: responses of gram-positive bacteria to low pH. Microbiol Mol Biol Rev (2003) 3.54
Bacterial osmoadaptation: the role of osmolytes in bacterial stress and virulence. FEMS Microbiol Rev (2002) 3.40
Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118. Proc Natl Acad Sci U S A (2007) 3.32
Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids. Nutr Rev (2010) 3.30
Bacteriocins - a viable alternative to antibiotics? Nat Rev Microbiol (2012) 2.76
Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome. Proc Natl Acad Sci U S A (2008) 2.53
The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II. Mol Microbiol (2006) 2.53
Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity. Gut (2012) 2.24
Bacterial lantibiotics: strategies to improve therapeutic potential. Curr Protein Pept Sci (2005) 2.21
Bile salt hydrolase activity in probiotics. Appl Environ Microbiol (2006) 2.19
Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion. J Bacteriol (2007) 2.15
Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon. Proc Natl Acad Sci U S A (2010) 2.11
The interplay between classical and alternative isoprenoid biosynthesis controls gammadelta T cell bioactivity of Listeria monocytogenes. FEBS Lett (2004) 1.93
Contribution of three bile-associated loci, bsh, pva, and btlB, to gastrointestinal persistence and bile tolerance of Listeria monocytogenes. Infect Immun (2005) 1.90
Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile. Proc Natl Acad Sci U S A (2010) 1.89
Tools for functional postgenomic analysis of listeria monocytogenes. Appl Environ Microbiol (2008) 1.78
A PrfA-regulated bile exclusion system (BilE) is a novel virulence factor in Listeria monocytogenes. Mol Microbiol (2005) 1.74
High-throughput sequencing reveals the incomplete, short-term recovery of infant gut microbiota following parenteral antibiotic treatment with ampicillin and gentamicin. Antimicrob Agents Chemother (2012) 1.69
Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins. Appl Environ Microbiol (2009) 1.68
The generation of nisin variants with enhanced activity against specific gram-positive pathogens. Mol Microbiol (2008) 1.62
Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity. Biochemistry (2004) 1.61
Bacteriophages φMR299-2 and φNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells. MBio (2012) 1.59
Bacteriocin production: a probiotic trait? Appl Environ Microbiol (2011) 1.57
Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ. Therap Adv Gastroenterol (2013) 1.56
Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro. Appl Environ Microbiol (2007) 1.54
Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes. PLoS Pathog (2008) 1.53
The gut microbiota and its relationship to diet and obesity: new insights. Gut Microbes (2012) 1.52
Novel luciferase reporter system for in vitro and organ-specific monitoring of differential gene expression in Listeria monocytogenes. Appl Environ Microbiol (2006) 1.50
Bacteriophage and their lysins for elimination of infectious bacteria. FEMS Microbiol Rev (2009) 1.48
Programming infant gut microbiota: influence of dietary and environmental factors. Curr Opin Biotechnol (2010) 1.48
Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection. PLoS Pathog (2011) 1.46
Bile stress response in Listeria monocytogenes LO28: adaptation, cross-protection, and identification of genetic loci involved in bile resistance. Appl Environ Microbiol (2002) 1.46
Multiple deletions of the osmolyte transporters BetL, Gbu, and OpuC of Listeria monocytogenes affect virulence and growth at high osmolarity. Appl Environ Microbiol (2002) 1.46
Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design. Mol Microbiol (2006) 1.45
Streptolysin S-like virulence factors: the continuing sagA. Nat Rev Microbiol (2011) 1.42
The LisRK signal transduction system determines the sensitivity of Listeria monocytogenes to nisin and cephalosporins. Antimicrob Agents Chemother (2002) 1.41
A five-strain probiotic combination reduces pathogen shedding and alleviates disease signs in pigs challenged with Salmonella enterica Serovar Typhimurium. Appl Environ Microbiol (2007) 1.38
Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseases. Mar Drugs (2011) 1.36
Clostridium difficile carriage in elderly subjects and associated changes in the intestinal microbiota. J Clin Microbiol (2011) 1.34
Bacteriophage-resistance systems in dairy starter strains: molecular analysis to application. Antonie Van Leeuwenhoek (2002) 1.34
Disruption of putative regulatory loci in Listeria monocytogenes demonstrates a significant role for Fur and PerR in virulence. Infect Immun (2004) 1.34
The CtsR regulator of Listeria monocytogenes contains a variant glycine repeat region that affects piezotolerance, stress resistance, motility and virulence. Mol Microbiol (2003) 1.33
Antimicrobial activity of lacticin 3,147 against clinical Clostridium difficile strains. J Med Microbiol (2007) 1.33
Isolation and analysis of bacteria with antimicrobial activities from the marine sponge Haliclona simulans collected from Irish waters. Mar Biotechnol (NY) (2008) 1.30
Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations. Antimicrob Agents Chemother (2005) 1.30
Discovery of medically significant lantibiotics. Curr Drug Discov Technol (2009) 1.29
The interaction between Listeria monocytogenes and the host gastrointestinal tract. Microbiology (2009) 1.29
AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes. Mol Microbiol (2009) 1.29
M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis. FEMS Immunol Med Microbiol (2007) 1.27
A postgenomic appraisal of osmotolerance in Listeria monocytogenes. Appl Environ Microbiol (2003) 1.26