CK2α is essential for embryonic morphogenesis.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 3756899)

Published in Mol Cell Biochem on July 15, 2011

Authors

Isabel Dominguez1, Irene R Degano, Kathleen Chea, Julie Cha, Paul Toselli, David C Seldin

Author Affiliations

1: Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. isdoming@bu.edu

Articles cited by this

One-thousand-and-one substrates of protein kinase CK2? FASEB J (2003) 6.89

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J (2003) 5.11

EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. Mol Cell (2009) 2.50

Protein kinase CK2 and its role in cellular proliferation, development and pathology. Electrophoresis (1999) 2.16

Isolation, sequencing, and disruption of the yeast CKA2 gene: casein kinase II is essential for viability in Saccharomyces cerevisiae. Mol Cell Biol (1990) 2.07

Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit. Nat Genet (1999) 1.90

Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality. Mol Cell Biol (2003) 1.85

The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development. Mol Cell Biol (2007) 1.52

CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J Biol Chem (2003) 1.51

Protein kinase CK2 in health and disease: CK2 and its role in Wnt and NF-kappaB signaling: linking development and cancer. Cell Mol Life Sci (2009) 1.50

Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. J Biol Chem (2000) 1.46

Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling. J Biol Chem (2006) 1.44

Order or chaos? An evaluation of the regulation of protein kinase CK2. Biochem Cell Biol (2004) 1.41

Protein kinase CK2--a key suppressor of apoptosis. Adv Enzyme Regul (2008) 1.39

Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors. Toxicol Pathol (2005) 1.34

CK2 as a positive regulator of Wnt signalling and tumourigenesis. Mol Cell Biochem (2005) 1.30

Protein kinase CK2: evidence for a protein kinase CK2beta subunit fraction, devoid of the catalytic CK2alpha subunit, in mouse brain and testicles. FEBS Lett (1999) 1.27

A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis. Genesis (2007) 1.22

The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta. Int J Biol Sci (2005) 1.21

The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton. Cell Signal (2005) 1.19

Protein kinase CK2alpha' is induced by serum as a delayed early gene and cooperates with Ha-ras in fibroblast transformation. J Biol Chem (1998) 1.17

Spermatogenesis of mice lacking CK2alpha': failure of germ cell survival and characteristic modifications of the spermatid nucleus. Mol Reprod Dev (2003) 1.17

A role for protein kinase CK2 in plant development: evidence obtained using a dominant-negative mutant. Plant J (2008) 1.13

Purification of rat liver nuclear protein kinase NII. J Biol Chem (1977) 1.13

Gene targeting of CK2 catalytic subunits. Mol Cell Biochem (2008) 1.12

Inhibition of protein kinase CK2 suppresses angiogenesis and hematopoietic stem cell recruitment to retinal neovascularization sites. Mol Cell Biochem (2008) 1.12

Live-cell fluorescence imaging reveals the dynamics of protein kinase CK2 individual subunits. Mol Cell Biol (2003) 1.12

Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos. Dev Biol (2004) 1.08

The raison d'être of constitutively active protein kinases: the lesson of CK2. Acc Chem Res (2003) 1.06

Protein kinase CK2, an important regulator of the inflammatory response? J Mol Med (Berl) (2008) 1.06

Protein kinase CK2: a new view of an old molecular complex. EMBO Rep (2004) 1.03

Inhibition of CK2 activity by TGF-beta1 promotes IkappaB-alpha protein stabilization and apoptosis of immortalized hepatocytes. Hepatology (2003) 1.03

Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro. Head Neck (2000) 1.03

The regulatory beta-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis. Oncogene (2008) 1.02

Response of cancer cells to molecular interruption of the CK2 signal. Mol Cell Biochem (2001) 1.02

Identifying interaction motifs in CK2beta--a ubiquitous kinase regulatory subunit. Trends Biochem Sci (2006) 1.00

Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation. Biochemistry (2009) 0.99

Casein kinase 2, circadian clocks, and the flight from mutagenic light. Mol Cell Biochem (2005) 0.98

Uncoupling of cell proliferation and differentiation activities of basic fibroblast growth factor. FASEB J (2000) 0.94

Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol (2010) 0.93

Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signaling. FASEB J (2009) 0.92

Transforming growth factor-beta-induced expression of the apolipoprotein E gene requires c-Jun N-terminal kinase, p38 kinase, and casein kinase 2. Arterioscler Thromb Vasc Biol (2006) 0.92

Threonine 393 of beta-catenin regulates interaction with Axin. J Cell Biochem (2009) 0.89

A role for CK2alpha/beta in Xenopus early embryonic development. Mol Cell Biochem (2005) 0.89

Tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: evaluation of their effects on cells and different molecular forms of human CK2. Biochim Biophys Acta (2005) 0.88

The tight association of protein kinase CK2 with plasma membranes is mediated by a specific domain of its regulatory beta-subunit. Biochim Biophys Acta (1998) 0.87

Drosophila CK2 regulates lateral-inhibition during eye and bristle development. Mech Dev (2006) 0.87

Distinctive features of plant protein kinase CK2. Mol Cell Biochem (2001) 0.86

Protein kinase CK2 interacts with adiponectin receptor 1 and participates in adiponectin signaling. Cell Signal (2009) 0.83

Inhibition of protein kinase CK2 expression and activity blocks tumor cell growth. Mol Cell Biochem (2009) 0.82

Validation of protein kinase CK2 as oncological target. Apoptosis (2005) 0.82

Knocking out the regulatory beta subunit of protein kinase CK2 in mice: gene dosage effects in ES cells and embryos. Mol Cell Biochem (2005) 0.81

Expression of casein kinase 2 during mouse embryogenesis. Acta Anat (Basel) (1994) 0.80

Articles by these authors

High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study. Ann Intern Med (2004) 4.05

The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest (2006) 3.49

Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial. Blood (2006) 2.97

Amyloidosis: pathogenesis and new therapeutic options. J Clin Oncol (2011) 2.82

Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients. Blood (2011) 2.72

Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway. Proc Natl Acad Sci U S A (2010) 2.41

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol (2008) 2.34

Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors. Am J Pathol (2002) 2.26

T1alpha, a lung type I cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth. Dev Biol (2003) 1.89

Long-term outcome of patients with AL amyloidosis treated with high-dose melphalan and stem-cell transplantation. Blood (2007) 1.83

Direct identification of PTEN phosphorylation sites. FEBS Lett (2002) 1.80

Persistent pleural effusions in primary systemic amyloidosis: etiology and prognosis. Chest (2003) 1.68

Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis. Blood (2011) 1.64

The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development. Mol Cell Biol (2007) 1.52

CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J Biol Chem (2003) 1.51

Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis. Cancer Res (2005) 1.50

Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells. Cancer Res (2002) 1.49

Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression. Blood (2004) 1.44

Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors. Oncogene (2002) 1.43

Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells. Cancer Res (2005) 1.41

Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors. Mol Cell Biol (2003) 1.36

Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis. Oncogene (2002) 1.34

Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors. Toxicol Pathol (2005) 1.34

RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland. Mol Cell Biol (2005) 1.32

A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis. Biol Chem (2006) 1.26

New hematologic response criteria predict survival in patients with immunoglobulin light chain amyloidosis treated with high-dose melphalan and autologous stem-cell transplantation. J Clin Oncol (2013) 1.23

Cardiac amyloidosis in African Americans: comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis. Am Heart J (2009) 1.20

Soft tissue, joint, and bone manifestations of AL amyloidosis: clinical presentation, molecular features, and survival. Arthritis Rheum (2007) 1.20

Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience. Haematologica (2012) 1.19

Immunoglobulin light chain amyloidosis. Expert Rev Hematol (2013) 1.15

Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue. Mol Cell Proteomics (2008) 1.14

Gene targeting of CK2 catalytic subunits. Mol Cell Biochem (2008) 1.12

1H NMR determination of base-pair lifetimes in oligonucleotides containing single base mismatches. Nucleic Acids Res (2002) 1.11

Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos. Dev Biol (2004) 1.08

Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish. Am J Physiol Heart Circ Physiol (2013) 1.06

The critical role of the constant region in thermal stability and aggregation of amyloidogenic immunoglobulin light chain. Biochemistry (2010) 1.05

Adipocyte accumulation in penile corpus cavernosum of the orchiectomized rabbit: a potential mechanism for veno-occlusive dysfunction in androgen deficiency. J Androl (2005) 1.04

Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure. Transplantation (2010) 1.04

Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype. Cancer Res (2007) 1.02

An overview of high-dose melphalan and stem cell transplantation in the treatment of AL amyloidosis. Amyloid (2007) 1.00

Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II trial. Haematologica (2012) 1.00

Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens. Mol Vis (2009) 0.97

Role of glycosaminoglycan sulfation in the formation of immunoglobulin light chain amyloid oligomers and fibrils. J Biol Chem (2010) 0.97

Spontaneous rupture of the liver in a patient with systemic AL amyloidosis undergoing treatment with high-dose melphalan and autologous stem cell transplantation: a case report with literature review. Amyloid (2009) 0.97

Effects of elastase on the mechanical and failure properties of engineered elastin-rich matrices. J Appl Physiol (1985) (2005) 0.97

Evidence for a functional role of the molecular chaperone clusterin in amyloidotic cardiomyopathy. Am J Pathol (2010) 0.97

Downregulation of lysyl oxidase and upregulation of cellular thiols in rat fetal lung fibroblasts treated with cigarette smoke condensate. Toxicol Sci (2004) 0.96

Expression of membrane-associated mucins MUC1 and MUC4 in major human salivary glands. J Histochem Cytochem (2002) 0.95

High-dose melphalan and stem cell transplantation for patients with AL amyloidosis: trends in treatment-related mortality over the past 17 years at a single referral center. Blood (2012) 0.95

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity. J Neurosci (2013) 0.95

Incidence and outcome of acute renal failure complicating autologous stem cell transplantation for AL amyloidosis. Kidney Int (2003) 0.94

A new lysozyme tyr54asn mutation causing amyloidosis in a family of Swedish ancestry with gastrointestinal symptoms. Amyloid (2012) 0.94

Lymphadenopathy as a manifestation of amyloidosis: a case series. Amyloid (2014) 0.94

Epithelial-to-mesenchymal transition induced by TGF-β1 is mediated by Blimp-1-dependent repression of BMP-5. Cancer Res (2012) 0.94

Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis. Amyloid (2005) 0.93

Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic kappa1 immunoglobulin light chains. Biochemistry (2007) 0.93

Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity. Basic Res Cardiol (2013) 0.91

The impact of a recent relapse on patient-reported outcomes in subjects with multiple sclerosis. Qual Life Res (2012) 0.91

Increases in B-type natriuretic peptide (BNP) during treatment with lenalidomide in AL amyloidosis. Blood (2010) 0.91

Cloning and characterization of the rat lysyl oxidase gene promoter: identification of core promoter elements and functional nuclear factor I-binding sites. J Biol Chem (2007) 0.91

Impaired 3',5'-cyclic adenosine monophosphate-mediated signaling in immediate early responsive gene X-1-deficient vascular smooth muscle cells. Hypertension (2010) 0.90

Localized amyloidosis of the breast: a case series. Amyloid (2011) 0.90

Threonine 393 of beta-catenin regulates interaction with Axin. J Cell Biochem (2009) 0.89

A solitary mediastinal mass due to localized AL amyloidosis: case report and review of the literature. Amyloid (2013) 0.89

Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis. Stem Cell Reports (2013) 0.89

A role for CK2alpha/beta in Xenopus early embryonic development. Mol Cell Biochem (2005) 0.89

Dynamic expression of a LEF-EGFP Wnt reporter in mouse development and cancer. Genesis (2010) 0.88

Two distinct phosphorylation events govern the function of muscle FHOD3. Cell Mol Life Sci (2012) 0.88

Overexpression of human amyloidogenic light chains causes heart failure in embryonic zebrafish: a preliminary report. Amyloid (2012) 0.88

Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors. Biochem J (2012) 0.88

Inhibition of the expression of lysyl oxidase and its substrates in cadmium-resistant rat fetal lung fibroblasts. Toxicol Sci (2006) 0.88

Matrix metalloproteinases and their tissue inhibitors in cardiac amyloidosis: relationship to structural, functional myocardial changes and to light chain amyloid deposition. Circ Heart Fail (2008) 0.88

Myocardial infarction with "clean coronaries" caused by amyloid light-chain AL amyloidosis: a case report and literature review. Amyloid (2011) 0.88

Transcriptional and posttranscriptional inhibition of lysyl oxidase expression by cigarette smoke condensate in cultured rat fetal lung fibroblasts. Toxicol Sci (2005) 0.87

Hepatic response after high-dose melphalan and stem cell transplantation in patients with AL amyloidosis associated liver disease. Haematologica (2009) 0.87

Durable hematologic complete responses can be achieved with lenalidomide in AL amyloidosis. Blood (2010) 0.86

AL-Base: a visual platform analysis tool for the study of amyloidogenic immunoglobulin light chain sequences. Amyloid (2009) 0.85

Bortezomib and high-dose melphalan conditioning for stem cell transplantation for AL amyloidosis: a pilot study. Haematologica (2011) 0.85

Association of acquired von Willebrand syndrome with AL amyloidosis. Am J Hematol (2007) 0.85

Short and long-term outcome of treatment with high-dose melphalan and stem cell transplantation for multiple myeloma-associated AL amyloidosis. Ann Hematol (2009) 0.84

Low-dose continuous oral melphalan for the treatment of primary systemic (AL) amyloidosis. Br J Haematol (2002) 0.84

Perturbation of copper (Cu) homeostasis and expression of Cu-binding proteins in cadmium-resistant lung fibroblasts. Toxicol Sci (2007) 0.83

Oral cyclic melphalan and dexamethasone for patients with AL amyloidosis. Clin Lymphoma Myeloma Leuk (2010) 0.83

Kidney dysfunction during lenalidomide treatment for AL amyloidosis. Nephrol Dial Transplant (2010) 0.83

The critical role of the cellular thiol homeostasis in cadmium perturbation of the lung extracellular matrix. Toxicology (2009) 0.81

Angiotensin II type 1 and bradykinin B2 receptors expressed in early stage epithelial cells derived from human embryonic stem cells. J Cell Physiol (2007) 0.81

Macroglossia - not always AL amyloidosis. Amyloid (2011) 0.80

B-Myb represses vascular smooth muscle cell collagen gene expression and inhibits neointima formation after arterial injury. Arterioscler Thromb Vasc Biol (2004) 0.80

Hypoxia-response element (HRE)-directed transcriptional regulation of the rat lysyl oxidase gene in response to cobalt and cadmium. Toxicol Sci (2012) 0.80

Vertebral compression fractures as the initial presentation of AL amyloidosis: case series and review of literature. Amyloid (2015) 0.79

B-Myb represses elastin gene expression in aortic smooth muscle cells. J Biol Chem (2004) 0.79

High-dose intravenous melphalan with autologous stem cell transplantation in AL amyloidosis-associated end-stage renal disease. Kidney Int (2003) 0.79

Developmental and growth defects in mice with combined deficiency of CK2 catalytic genes. Mol Cell Biochem (2011) 0.78

Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt). Hum Genet (2014) 0.78

Amyloid deposits in the bone marrow of patients with immunoglobulin light chain amyloidosis do not impact stem cell mobilization or engraftment. Biol Blood Marrow Transplant (2012) 0.78

Risk of second primary malignancy in patients with AL amyloidosis treated with lenalidomide. Am J Hematol (2013) 0.78

Transgenic expression of an altered angiotensin type I AT1 receptor resulting in marked modulation of vascular type I collagen. J Cell Physiol (2012) 0.78