Robert S Negrin

Author PubWeight™ 123.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med 2003 7.78
2 Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A 2003 4.41
3 Protective conditioning for acute graft-versus-host disease. N Engl J Med 2005 4.07
4 Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production. Blood 2006 3.33
5 Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells. Blood 2007 3.27
6 In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets. Blood 2005 3.13
7 Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD. Blood 2004 2.95
8 Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system. Annu Rev Med 2005 2.92
9 Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging. Blood 2002 2.79
10 Synergistic antitumor effects of immune cell-viral biotherapy. Science 2006 2.37
11 Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells. Cell Stem Cell 2011 2.35
12 Role of NKG2D signaling in the cytotoxicity of activated and expanded CD8+ T cells. Blood 2003 2.27
13 Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity. Blood 2007 2.19
14 Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease. Biol Blood Marrow Transplant 2005 2.12
15 Reconstitution of NK cell receptor repertoire following HLA-matched hematopoietic cell transplantation. Blood 2003 2.08
16 Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation. Proc Natl Acad Sci U S A 2009 2.02
17 Adoptive immunotherapy with cytokine-induced killer cells for patients with relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2011 1.96
18 In vivo dynamics of regulatory T-cell trafficking and survival predict effective strategies to control graft-versus-host disease following allogeneic transplantation. Blood 2006 1.89
19 TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors. Blood 2009 1.89
20 Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation 2005 1.82
21 In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity. Blood 2008 1.67
22 A phase I trial of autologous cytokine-induced killer cells for the treatment of relapsed Hodgkin disease and non-Hodgkin lymphoma. Biol Blood Marrow Transplant 2005 1.60
23 The impact of regulatory T cells on T-cell immunity following hematopoietic cell transplantation. Blood 2007 1.57
24 Rituximab as adjuvant to high-dose therapy and autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma. Blood 2003 1.55
25 NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects. Blood 2010 1.49
26 Long-term outcome of patients with metastatic breast cancer treated with high-dose chemotherapy and transplantation of purified autologous hematopoietic stem cells. Biol Blood Marrow Transplant 2011 1.49
27 Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organs. Blood 2007 1.48
28 Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cells. Blood 2013 1.47
29 Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells. Blood 2011 1.44
30 Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells. Blood 2012 1.43
31 Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells. J Immunol 2005 1.35
32 Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation. J Immunol 2008 1.34
33 Long-term remission of Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic hematopoietic cell transplantation from matched sibling donors: a 20-year experience with the fractionated total body irradiation-etoposide regimen. Blood 2008 1.33
34 Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease. Blood 2006 1.31
35 Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence. Blood 2012 1.31
36 Role of naturally arising regulatory T cells in hematopoietic cell transplantation. Biol Blood Marrow Transplant 2006 1.29
37 Evaluation of effector cell fate and function by in vivo bioluminescence imaging. Methods 2003 1.25
38 Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study. Clin Cancer Res 2006 1.20
39 Follicular lymphoma B cells induce the conversion of conventional CD4+ T cells to T-regulatory cells. Int J Cancer 2009 1.19
40 Interleukin-2 receptor downstream events in regulatory T cells: implications for the choice of immunosuppressive drug therapy. Cell Cycle 2007 1.15
41 Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4-dependent mechanism. Blood 2011 1.11
42 Randomized trial of allogeneic related bone marrow transplantation versus peripheral blood stem cell transplantation for chronic myeloid leukemia. Biol Blood Marrow Transplant 2005 1.10
43 Autologous versus reduced-intensity allogeneic hematopoietic cell transplantation for patients with chemosensitive follicular non-Hodgkin lymphoma beyond first complete response or first partial response. Biol Blood Marrow Transplant 2010 1.10
44 The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia. Blood 2006 1.08
45 Understanding immune cell trafficking patterns via in vivo bioluminescence imaging. J Cell Biochem Suppl 2002 1.07
46 Regulatory T cells and natural killer T cells for modulation of GVHD following allogeneic hematopoietic cell transplantation. Blood 2013 1.07
47 Immunoglobulin G Fc receptor FcgammaRIIIa 158 V/F polymorphism correlates with rituximab-induced neutropenia after autologous transplantation in patients with non-Hodgkin's lymphoma. J Clin Oncol 2009 1.04
48 Engraftment and survival following reduced-intensity allogeneic peripheral blood hematopoietic cell transplantation is affected by CD8+ T-cell dose. Blood 2004 1.02
49 Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3. Cancer Res 2002 1.02
50 CD101 surface expression discriminates potency among murine FoxP3+ regulatory T cells. J Immunol 2007 1.02
51 Tissue-specific homing and expansion of donor NK cells in allogeneic bone marrow transplantation. J Immunol 2009 1.01
52 CD8+CD44(hi) but not CD4+CD44(hi) memory T cells mediate potent graft antilymphoma activity without GVHD. Blood 2011 1.01
53 Long-term results of autologous hematopoietic cell transplantation for peripheral T cell lymphoma: the Stanford experience. Biol Blood Marrow Transplant 2008 1.01
54 Long-term outcomes after transplantation of HLA-identical related G-CSF-mobilized peripheral blood mononuclear cells versus bone marrow. Blood 2012 0.99
55 Low levels of Her2/neu expressed by Ewing's family tumor cell lines can redirect cytokine-induced killer cells. Clin Cancer Res 2005 0.96
56 Cytomegalovirus viral load and virus-specific immune reconstitution after peripheral blood stem cell versus bone marrow transplantation. Biol Blood Marrow Transplant 2011 0.95
57 Studies of ex vivo activated and expanded CD8+ NK-T cells in humans and mice. J Clin Immunol 2002 0.94
58 Natural killer cells in allogeneic transplantation: effect on engraftment, graft- versus-tumor, and graft-versus-host responses. Biol Blood Marrow Transplant 2009 0.94
59 Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells. Cancer Res 2010 0.93
60 Regulation of different inflammatory diseases by impacting the mevalonate pathway. Immunology 2009 0.93
61 A distinct evolution of the T-cell repertoire categorizes treatment refractory gastrointestinal acute graft-versus-host disease. Blood 2013 0.93
62 High-dose carmustine, etoposide, and cyclophosphamide followed by allogeneic hematopoietic cell transplantation for non-Hodgkin lymphoma. Biol Blood Marrow Transplant 2006 0.93
63 Biology and clinical effects of natural killer cells in allogeneic transplantation. Curr Opin Oncol 2010 0.92
64 CD34, CD4, and CD8 cell doses do not influence engraftment, graft-versus-host disease, or survival following myeloablative human leukocyte antigen-identical peripheral blood allografting for hematologic malignancies. Exp Hematol 2005 0.91
65 Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host disease. Biol Blood Marrow Transplant 2007 0.91
66 CXCL12 mediates immunosuppression in the lymphoma microenvironment after allogeneic transplantation of hematopoietic cells. Cancer Res 2010 0.90
67 Multi-modality imaging identifies key times for annexin V imaging as an early predictor of therapeutic outcome. Mol Imaging 2004 0.89
68 Phase I/II trial of GN-BVC, a gemcitabine and vinorelbine-containing conditioning regimen for autologous hematopoietic cell transplantation in recurrent and refractory hodgkin lymphoma. Biol Blood Marrow Transplant 2010 0.86
69 Ex vivo expanded dendritic cells home to T-cell zones of lymphoid organs and survive in vivo after allogeneic bone marrow transplantation. Am J Pathol 2005 0.86
70 Donor hematopoiesis in mice following total lymphoid irradiation requires host T-regulatory cells for durable engraftment. Blood 2014 0.85
71 A novel technique for the enrichment of primary ovarian cancer cells. Am J Obstet Gynecol 2007 0.85
72 Salvage allogeneic hematopoietic cell transplantation with fludarabine and low-dose total body irradiation after rejection of first allografts. Biol Blood Marrow Transplant 2009 0.84
73 Cancer vaccines and T cell therapy. Biol Blood Marrow Transplant 2012 0.83
74 A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model. BMC Med 2013 0.83
75 Treatment of 4T1 metastatic breast cancer with combined hypofractionated irradiation and autologous T-cell infusion. Radiat Res 2014 0.82
76 Natural and expanded CD4(+)CD25(+) regulatory T cells in bone marrow transplantation. Biol Blood Marrow Transplant 2011 0.82
77 Plasmacytoid dendritic cells take up opsonized antigen leading to CD4+ and CD8+ T cell activation in vivo. J Immunol 2008 0.81
78 Mapping immune processes in intact tissues at cellular resolution. J Clin Invest 2012 0.80
79 Acute graft-versus-host disease-challenge for a broader application of allogeneic hematopoietic cell transplantation. Curr Stem Cell Res Ther 2006 0.79
80 IL-17 gene ablation does not impact Treg-mediated suppression of graft-versus-host disease after bone marrow transplantation. Biol Blood Marrow Transplant 2013 0.78
81 Co-transplantation of pure blood stem cells with antigen-specific but not bulk T cells augments functional immunity. Proc Natl Acad Sci U S A 2012 0.78
82 Methods for imaging cell fates in hematopoiesis. Methods Mol Med 2007 0.78
83 A killer choice for cancer immunotherapy. Immunol Res 2014 0.77
84 Engraftment of embryonic stem cells and differentiated progeny by host conditioning with total lymphoid irradiation and regulatory T cells. Cell Rep 2015 0.76
85 A new approach for eradication of residual lymphoma cells by host nonreactive anti-third-party central memory CD8 T cells. Blood 2013 0.76
86 Immune regulatory networks in the post-transplant setting. Blood Cells Mol Dis 2007 0.75