Published in Mitochondrion on July 20, 2011
A two-way street: reciprocal regulation of metabolism and signalling. Nat Rev Mol Cell Biol (2012) 2.35
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. J Biol Chem (2013) 1.20
Sirtuin activators and inhibitors. Biofactors (2012) 1.19
Protective effects of sirtuins in cardiovascular diseases: from bench to bedside. Eur Heart J (2015) 1.11
Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3-mediated deacetylation of cyclophilin D in breast carcinoma. Cell Death Dis (2013) 0.89
Stanniocalcin-1 inhibits renal ischemia/reperfusion injury via an AMP-activated protein kinase-dependent pathway. J Am Soc Nephrol (2014) 0.86
The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells. Int J Cell Biol (2012) 0.85
Sources and implications of NADH/NAD(+) redox imbalance in diabetes and its complications. Diabetes Metab Syndr Obes (2016) 0.80
Back to the future: transgenerational transmission of xenobiotic-induced epigenetic remodeling. Epigenetics (2015) 0.78
Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart. Mech Ageing Dev (2015) 0.76
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science (2007) 3.92
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. J Cell Biol (2006) 3.87
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis. Mol Cell (2004) 3.28
PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science (2010) 3.21
Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1. Cell Metab (2008) 2.22
Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria. J Cell Biol (2002) 2.08
Doxorubicin: the good, the bad and the ugly effect. Curr Med Chem (2009) 1.95
Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. Cell Cycle (2013) 1.94
Mitochondria-ros crosstalk in the control of cell death and aging. J Signal Transduct (2011) 1.89
A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction. Aging (Albany NY) (2010) 1.70
Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles. Int J Biochem Cell Biol (2009) 1.64
Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. Mol Biol Cell (2005) 1.58
Diabetes and the impairment of reproductive function: possible role of mitochondria and reactive oxygen species. Curr Diabetes Rev (2008) 1.40
Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterization. J Biochem Mol Toxicol (2007) 1.39
Mitochondrial Ca(2+) and apoptosis. Cell Calcium (2012) 1.36
Calcium signaling around Mitochondria Associated Membranes (MAMs). Cell Commun Signal (2011) 1.33
Cardiotoxicity of the anticancer therapeutic agent bortezomib. Am J Pathol (2010) 1.17
Relation between mitochondrial membrane potential and ROS formation. Methods Mol Biol (2012) 1.10
Doxorubicin-induced cardiotoxicity: from bioenergetic failure and cell death to cardiomyopathy. Med Res Rev (2013) 1.10
Mitochondria-associated membranes: composition, molecular mechanisms, and physiopathological implications. Antioxid Redox Signal (2015) 1.09
Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biol Toxicol (2008) 1.08
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions. J Pharmacol Exp Ther (2007) 1.08
Mitochondria as an important target in heavy metal toxicity in rat hepatoma AS-30D cells. Toxicol Appl Pharmacol (2008) 1.07
Role of mitochondria in nonalcoholic fatty liver disease--from origin to propagation. Clin Biochem (2012) 1.03
Mitochondrial involvement in cardiac apoptosis during ischemia and reperfusion: can we close the box? Cardiovasc Toxicol (2009) 1.02
Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line. Cancer Chemother Pharmacol (2007) 1.02
Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis. Am J Physiol Heart Circ Physiol (2005) 1.01
Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency. PLoS One (2013) 1.00
Parabens in male infertility-is there a mitochondrial connection? Reprod Toxicol (2008) 1.00
Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety? Curr Drug Saf (2009) 0.99
Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes. J Cell Biol (2004) 0.97
Evaluation of respiration with clark type electrode in isolated mitochondria and permeabilized animal cells. Methods Mol Biol (2012) 0.97
Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C. Oxid Med Cell Longev (2013) 0.96
Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. Mitochondrion (2011) 0.96
Rapid human melanoma cell death induced by sanguinarine through oxidative stress. Eur J Pharmacol (2013) 0.95
Mitochondria in chronic liver disease. Curr Drug Targets (2011) 0.93
Differential immuno-reactivity to genomic DNA, RNA and mitochondrial DNA is associated with auto-immunity. Cell Physiol Biochem (2014) 0.93
Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units. Adv Exp Med Biol (2012) 0.92
Drug-induced cardiac mitochondrial toxicity and protection: from doxorubicin to carvedilol. Curr Pharm Des (2011) 0.92
Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells. Chem Res Toxicol (2011) 0.92
Berberine as a promising safe anti-cancer agent - is there a role for mitochondria? Curr Drug Targets (2011) 0.91
Differentiation-dependent doxorubicin toxicity on H9c2 cardiomyoblasts. Cardiovasc Toxicol (2012) 0.91
Doxorubicin increases the susceptibility of brain mitochondria to Ca(2+)-induced permeability transition and oxidative damage. Free Radic Biol Med (2008) 0.90
Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria). Folia Neuropathol (2011) 0.89
Acute exercise protects against calcium-induced cardiac mitochondrial permeability transition pore opening in doxorubicin-treated rats. Clin Sci (Lond) (2011) 0.89
Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death. BMC Cell Biol (2007) 0.89
Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts. Cancer Chemother Pharmacol (2009) 0.89
ATP synthesis and storage. Purinergic Signal (2012) 0.89
Mitochondrial fatty acid oxidation and oxidative stress: lack of reverse electron transfer-associated production of reactive oxygen species. Biochim Biophys Acta (2010) 0.88
Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contents. Biochim Biophys Acta (2003) 0.88
Mitochondrial membrane lipid remodeling in pathophysiology: a new target for diet and therapeutic interventions. Prog Lipid Res (2013) 0.87
Physical exercise as a possible strategy for brain protection: evidence from mitochondrial-mediated mechanisms. Prog Neurobiol (2012) 0.87
Mitochondrial remodeling in cancer metabolism and survival: potential for new therapies. Biochim Biophys Acta (2012) 0.87
Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia. Mitochondrion (2010) 0.87
Isoproterenol cytotoxicity is dependent on the differentiation state of the cardiomyoblast H9c2 cell line. Cardiovasc Toxicol (2011) 0.86
Mechanisms of berberine (natural yellow 18)-induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator. Toxicol Sci (2008) 0.86
Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen. J Steroid Biochem Mol Biol (2010) 0.86
Quercetin, kaempferol and biapigenin from Hypericum perforatum are neuroprotective against excitotoxic insults. Neurotox Res (2008) 0.86
The contribution of oxidative stress to drug-induced organ toxicity and its detection in vitro and in vivo. Expert Opin Drug Metab Toxicol (2012) 0.85
Mitochondria in cancer stem cells: a target for therapy. Recent Pat Endocr Metab Immune Drug Discov (2013) 0.85
Metabolic remodeling during H9c2 myoblast differentiation: relevance for in vitro toxicity studies. Cardiovasc Toxicol (2011) 0.85
Effect of mtDNA point mutations on cellular bioenergetics. Biochim Biophys Acta (2012) 0.84
Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders. Biochim Biophys Acta (2010) 0.83
Left ventricular noncompaction (LVNC) and low mitochondrial membrane potential are specific for Barth syndrome. J Inherit Metab Dis (2013) 0.83
Beneficial effects of exercise on muscle mitochondrial function in diabetes mellitus. Sports Med (2008) 0.83
Vitamin E prevents hypobaric hypoxia-induced mitochondrial dysfunction in skeletal muscle. Clin Sci (Lond) (2007) 0.83
Mitochondria as a target for exercise-induced cardioprotection. Curr Drug Targets (2011) 0.82
Plasma membrane associated membranes (PAM) from Jurkat cells contain STIM1 protein is PAM involved in the capacitative calcium entry? Int J Biochem Cell Biol (2009) 0.82
Targeting mitochondrial function for the treatment of breast cancer. Future Med Chem (2014) 0.82
Endurance training limits the functional alterations of rat heart mitochondria submitted to in vitro anoxia-reoxygenation. Int J Cardiol (2005) 0.82
Mitochondria associated membranes (MAMs) as critical hubs for apoptosis. Commun Integr Biol (2011) 0.82
Effects of N-acylethanolamines on mitochondrial energetics and permeability transition. Biochim Biophys Acta (2004) 0.82
Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells--nuclear vs. mitochondrial effects. Biochem Pharmacol (2008) 0.82
Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity. J Pineal Res (2011) 0.82
Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells. Anticancer Drugs (2011) 0.82
Interaction of carbonylcyanide p-trifluoromethoxyphenylhydrazone (FCCP) with lipid membrane systems: a biophysical approach with relevance to mitochondrial uncoupling. J Bioenerg Biomembr (2011) 0.82
Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain. PLoS One (2013) 0.81
Toxicity evaluation of some traditional African spices on breast cancer cells and isolated rat hepatic mitochondria. Food Chem Toxicol (2012) 0.81
Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling. Int J Biochem Cell Biol (2012) 0.81
Bisphenol A as epigenetic modulator: setting the stage for carcinogenesis? Eur J Clin Invest (2015) 0.81
Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations -- Relevance for carbaryl toxicity mechanisms. Chemosphere (2006) 0.80
Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition. Bioorg Med Chem (2013) 0.80
Substrate selection in hearts subjected to ischemia/reperfusion: role of cardioplegic solutions and gender. NMR Biomed (2011) 0.80
Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak. FEBS Lett (2008) 0.80
Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats. Mitochondrion (2008) 0.80
Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol. Mitochondrion (2003) 0.80
Endurance training improves gastrocnemius mitochondrial function despite increased susceptibility to permeability transition. Mitochondrion (2009) 0.80
Bile acids are toxic for isolated cardiac mitochondria: a possible cause for hepatic-derived cardiomyopathies? Cardiovasc Toxicol (2005) 0.80
Rapeseed oil-rich diet alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics. Arch Toxicol (2013) 0.79
Reactive oxygen species produced by the mitochondrial respiratory chain are involved in Cd2+-induced injury of rat ascites hepatoma AS-30D cells. Biochim Biophys Acta (2006) 0.79
A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes. World J Gastroenterol (2013) 0.79
A biophysical approach to menadione membrane interactions: relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects. Biochim Biophys Acta (2013) 0.78
Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar rats. Environ Pollut (2013) 0.78
Mitochondrial tolerance to drugs and toxic agents in ageing and disease. Curr Drug Targets (2011) 0.78
Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: differential activation of stress and survival pathways. Int J Biochem Cell Biol (2013) 0.78
The interplay between p66Shc, reactive oxygen species and cancer cell metabolism. Eur J Clin Invest (2015) 0.78
Ipilimumab and vemurafenib: two different routes for targeting melanoma. Curr Cancer Drug Targets (2013) 0.78