PubRank

Annamaria Biroccio

Author PubWeight™ 32.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Potentiation of the antitumoral activity of gemcitabine and paclitaxel in combination on human breast cancer cells. Cancer Biol Ther 2005 1.65
2 c-Myc phosphorylation is required for cellular response to oxidative stress. Mol Cell 2006 1.64
3 Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc Natl Acad Sci U S A 2009 1.59
4 TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage. Cell 2010 1.50
5 Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect. J Clin Invest 2007 1.39
6 Biological activity of the G-quadruplex ligand RHPS4 (3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate) is associated with telomere capping alteration. Mol Pharmacol 2004 1.37
7 Bcl-2 overexpression in human melanoma cells increases angiogenesis through VEGF mRNA stabilization and HIF-1-mediated transcriptional activity. FASEB J 2002 1.37
8 Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation. Mol Pharmacol 2002 1.34
9 Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy. J Clin Oncol 2003 1.34
10 Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway. Nucleic Acids Res 2009 1.29
11 G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors. Clin Cancer Res 2008 0.97
12 In vivo administration of liposomal vincristine sensitizes drug-resistant human solid tumors. Int J Cancer 2004 0.94
13 Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter. J Biol Chem 2003 0.93
14 Therapeutic integration of c-myc and bcl-2 antisense molecules with docetaxel in a preclinical model of hormone-refractory prostate cancer. Prostate 2007 0.91
15 Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis. Nucleic Acids Res 2013 0.90
16 ZD1839 (IRESSA), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells. Int J Cancer 2002 0.88
17 Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death. J Med Chem 2012 0.85
18 N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage. J Med Chem 2011 0.84
19 Alpha-tocopherol protects against cisplatin-induced toxicity without interfering with antitumor efficacy. Int J Cancer 2003 0.83
20 Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence. J Med Chem 2013 0.83
21 On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts. J Exp Clin Cancer Res 2013 0.83
22 Gamma-glutamylcysteine synthetase mediates the c-Myc-dependent response to antineoplastic agents in melanoma cells. Mol Pharmacol 2007 0.82
23 Endothelin-1 acts as a survival factor in ovarian carcinoma cells. Clin Sci (Lond) 2002 0.80
24 Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor. Mol Pharmacol 2003 0.79
25 Aromatase inhibitor exemestane has antiproliferative effects on human mesothelioma cells. J Thorac Oncol 2011 0.79
26 Looking for efficient G-quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug-like molecules. ChemMedChem 2015 0.78
27 Identification of novel interactors of human telomeric G-quadruplex DNA. Chem Commun (Camb) 2015 0.78
28 Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells. ChemMedChem 2012 0.77
29 Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft. J Transl Med 2011 0.77
30 Antiproliferative effect of Aurora kinase targeting in mesothelioma. Lung Cancer 2010 0.76
31 Methods of studying telomere damage induced by quadruplex-ligand complexes. Methods 2012 0.76
32 Shading the TRF2 recruiting function: a new horizon in drug development. J Am Chem Soc 2014 0.76
33 Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage. Org Biomol Chem 2014 0.75