Published in Trials on August 02, 2011
Classic Yin and Yang Tonic Formula for Osteopenia (CYYTO) | NCT01271647
Network understanding of herb medicine via rapid identification of ingredient-target interactions. Sci Rep (2014) 0.78
Golden plaster for pain therapy in patients with knee osteoarthritis: study protocol for a multicenter randomized, double-blind, placebo-controlled trial. Trials (2013) 0.75
A water extract of Malva verticillata seeds suppresses osteoclastogenesis and bone resorption stimulated by RANK ligand. BMC Complement Altern Med (2016) 0.75
Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J Clin Invest (2005) 5.19
Long-term prevention of postmenopausal osteoporosis by oestrogen. Evidence for an increased bone mass after delayed onset of oestrogen treatment. Lancet (1976) 4.24
Long-term risk of incident vertebral fractures. JAMA (2007) 3.15
Quality of life in patients with vertebral fractures: validation of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). Working Party for Quality of Life of the European Foundation for Osteoporosis. Osteoporos Int (1999) 2.20
Examining the validity of pressure ulcer risk assessment scales: developing and using illustrated patient simulations to collect the data. J Clin Nurs (2001) 1.95
Post-menopausal oestrogens protect against fractures of hip and distal radius. A case-control study. Lancet (1979) 1.92
The minimum effective dose of estrogen for prevention of postmenopausal bone loss. Obstet Gynecol (1984) 1.80
The risk and burden of vertebral fractures in Sweden. Osteoporos Int (2003) 1.74
Hormone replacement therapy and risk of hip fracture: population based case-control study. The Swedish Hip Fracture Study Group. BMJ (1998) 1.48
Prevalent vertebral fractures in black women and white women. J Bone Miner Res (2008) 1.25
Antifracture efficacy of long-term estrogens for osteoporosis. Trans Assoc Am Physicians (1973) 1.19
Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial. J Bone Miner Res (2007) 1.13
Population bone mineral density measurements for Chinese women and men in Hong Kong. Osteoporos Int (2001) 1.04
Measuring quality of life in women with vertebral fractures due to osteoporosis: a comparison of the OQLQ and QUALEFFO. Qual Life Res (2001) 1.04
Quantitative ultrasound and symptomatic vertebral fracture risk in Chinese women. Osteoporos Int (1999) 0.96
Development of a short osteoporosis quality of life questionnaire by equating items from two existing instruments. J Clin Epidemiol (2002) 0.93
A review of clinical trials of therapies for osteoporosis using fracture as an end point. J Clin Densitom (1999) 0.84
Distribution of isoflavonoids in non-leguminous taxa - an update. Phytochemistry (2006) 0.79
Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice. Arthritis Rheum (2011) 1.98
Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction. Arthritis Rheum (2008) 1.77
Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. Arthritis Rheum (2009) 1.54
Chinese herbal medicine for osteoporosis: a systematic review of randomized controlled trails. Evid Based Complement Alternat Med (2013) 1.49
Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation. J Biol Chem (2005) 1.44
Antithrombotic management of ischaemic stroke and transient ischaemic attack in China: a consecutive cross-sectional survey. Clin Exp Pharmacol Physiol (2010) 1.39
Stenting of symptomatic M1 stenosis of middle cerebral artery: an initial experience of 40 patients. Stroke (2004) 1.36
Near-infrared lymphatic imaging demonstrates the dynamics of lymph flow and lymphangiogenesis during the acute versus chronic phases of arthritis in mice. Arthritis Rheum (2010) 1.30
Stroke in China. Clin Exp Pharmacol Physiol (2009) 1.22
The epidemiological, clinical, and laboratory features of sporadic Creutzfeldt-Jakob disease patients in China: surveillance data from 2006 to 2010. PLoS One (2011) 1.21
Chinese guidelines for the secondary prevention of ischemic stroke and transient ischemic attack 2010. CNS Neurosci Ther (2012) 1.20
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. EMBO J (2007) 1.19
Stroke prevention in atrial fibrillation--an Asian stroke perspective. Heart Rhythm (2013) 1.07
Characterization of soybean genomic features by analysis of its expressed sequence tags. Theor Appl Genet (2003) 1.06
A continuous observation of the degenerative process in the intervertebral disc of Smad3 gene knock-out mice. Spine (Phila Pa 1976) (2009) 1.04
The membrane topology of RTN3 and its effect on binding of RTN3 to BACE1. J Biol Chem (2007) 1.02
Familial CJD associated PrP mutants within transmembrane region induced Ctm-PrP retention in ER and triggered apoptosis by ER stress in SH-SY5Y cells. PLoS One (2011) 1.02
Regional homogeneity within the default mode network in bipolar depression: a resting-state functional magnetic resonance imaging study. PLoS One (2012) 1.00
Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling. J Bone Miner Res (2010) 1.00
Implementation and outcome of thrombolysis with alteplase 3 to 4.5 h after acute stroke in Chinese patients. CNS Neurosci Ther (2012) 0.99
Clinical, histopathological and genetic studies in a family with fatal familial insomnia. Infect Genet Evol (2010) 0.98
Elevated levels of tau protein in cerebrospinal fluid of patients with probable Creutzfeldt-Jakob disease. Am J Med Sci (2010) 0.98
Psoralen stimulates osteoblast differentiation through activation of BMP signaling. Biochem Biophys Res Commun (2011) 0.98
DNA amplification and expression of FADD in oral squamous cell carcinoma. J Oral Pathol Med (2009) 0.97
Osteoarthritis: genetic factors, animal models, mechanisms, and therapies. Front Biosci (Elite Ed) (2012) 0.96
Heavy metal pollution recorded in Porites corals from Daya Bay, northern South China Sea. Mar Environ Res (2010) 0.96
Circulating MicroRNAs as potential risk biomarkers for hematoma enlargement after intracerebral hemorrhage. CNS Neurosci Ther (2012) 0.96
The distribution of human papillomavirus in tissues from patients with head and neck squamous cell carcinoma. Oncol Rep (2012) 0.95
Effect of hysteroscopy on the peritoneal dissemination of endometrial cancer cells: a meta-analysis. Fertil Steril (2011) 0.95
Chinese herbal medicine for chronic neck pain due to cervical degenerative disc disease. Cochrane Database Syst Rev (2010) 0.95
Clinical characteristics, management, and functional outcomes in Chinese patients within the first year after intracerebral hemorrhage: analysis from China National Stroke Registry. CNS Neurosci Ther (2012) 0.94
Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases. Autophagy (2012) 0.93
Human prion protein mutants with deleted and inserted octarepeats undergo different pathways to trigger cell apoptosis. J Mol Neurosci (2010) 0.93
Involvement of both cervical lymph nodes and retropharyngeal lymph nodes has prognostic value for N1 patients with nasopharyngeal carcinoma. Radiat Oncol (2014) 0.92
Environmental toxicants may modulate osteoblast differentiation by a mechanism involving the aryl hydrocarbon receptor. J Bone Miner Res (2007) 0.91
Human prion disease with a G114V mutation and epidemiological studies in a Chinese family: a case series. J Med Case Rep (2008) 0.91
Tris(ethyl-enediamine)zinc(II) hexa-fluorido-silicate. Acta Crystallogr Sect E Struct Rep Online (2009) 0.91
Cytosolic prion protein induces apoptosis in human neuronal cell SH-SY5Y via mitochondrial disruption pathway. BMB Rep (2009) 0.90
Resting-state abnormal baseline brain activity in unipolar and bipolar depression. Neurosci Lett (2012) 0.89
Metabolomics-based study of clinical and animal plasma samples in coronary heart disease with blood stasis syndrome. Evid Based Complement Alternat Med (2012) 0.89
Abnormal baseline brain activity in bipolar depression: a resting state functional magnetic resonance imaging study. Psychiatry Res (2012) 0.89
Interleukin-1beta attenuates renin gene expression via a mitogen-activated protein kinase kinase-extracellular signal-regulated kinase and signal transducer and activator of transcription 3-dependent mechanism in As4.1 cells. Endocrinology (2006) 0.89
Heat shock protein 104 inhibited the fibrillization of prion peptide 106-126 and disassembled prion peptide 106-126 fibrils in vitro. Int J Biochem Cell Biol (2011) 0.89
Clinical and familial characteristics of eight Chinese patients with T188K genetic Creutzfeldt-Jakob disease. Infect Genet Evol (2012) 0.88
Cervical intervertebral disc degeneration induced by unbalanced dynamic and static forces: a novel in vivo rat model. Spine (Phila Pa 1976) (2006) 0.88
Efficacy and safety of pramipexole in chinese patients with restless legs syndrome: results from a multi-center, randomized, double-blind, placebo-controlled trial. Sleep Med (2011) 0.88
Abnormal activation of microglia accompanied with disrupted CX3CR1/CX3CL1 pathway in the brains of the hamsters infected with scrapie agent 263K. J Mol Neurosci (2013) 0.88
The first Chinese case of Creutzfeldt-Jakob disease with mutation of E200K in PRNP. Biomed Environ Sci (2010) 0.88
Effect of in-hospital medical complications on case fatality post-acute ischemic stroke: data from the China National Stroke Registry. Chin Med J (Engl) (2012) 0.87
Comparative analysis of gene expression profiles between cortex and thalamus in Chinese fatal familial insomnia patients. Mol Neurobiol (2013) 0.87
A putative plasma membrane cation/proton antiporter from soybean confers salt tolerance in Arabidopsis. Plant Mol Biol (2005) 0.87
Patterns of insertion and deletion in Mammalian genomes. Curr Genomics (2007) 0.86
Efficacy and side effects of chinese herbal medicine for menopausal symptoms: a critical review. Evid Based Complement Alternat Med (2013) 0.86
Distribution and alteration of lymphatic vessels in knee joints of normal and osteoarthritic mice. Arthritis Rheumatol (2014) 0.86
Resting-state brain activity in major depressive disorder patients and their siblings. J Affect Disord (2013) 0.86
One-year clinical prediction in Chinese ischemic stroke patients using the CHADS2 and CHA2DS2-VASc scores: the China National Stroke Registry. CNS Neurosci Ther (2012) 0.86
The first Chinese case of Creutzfeldt-Jakob disease patient with R208H mutation in PRNP. Prion (2011) 0.85
Cytosolic PrP induces apoptosis of cell by disrupting microtubule assembly. J Mol Neurosci (2010) 0.85
The discodermolide hairpin structure flows from conformationally stable modular motifs. J Med Chem (2010) 0.85
PrP mutants with different numbers of octarepeat sequences are more susceptible to the oxidative stress. Sci China C Life Sci (2008) 0.85
The prepared tau exon-specific antibodies revealed distinct profiles of tau in CSF of the patients with Creutzfeldt-Jakob disease. PLoS One (2010) 0.85
The osteoprotective effect of psoralen in ovariectomy-induced osteoporotic rats via stimulating the osteoblastic differentiation from bone mesenchymal stem cells. Menopause (2012) 0.85
Herb formula "Fufangqishe-Pill" prevents upright posture-induced intervertebral disc degeneration at the lumbar in rats. J Pharmacol Sci (2010) 0.85
Interaction between amyloid precursor protein and Nogo receptors regulates amyloid deposition. FASEB J (2011) 0.85
Remarkable reduction of MAP2 in the brains of scrapie-infected rodents and human prion disease possibly correlated with the increase of calpain. PLoS One (2012) 0.85
A linkable identity privacy algorithm for HealthGrid. Stud Health Technol Inform (2005) 0.85
Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins. J Mol Biol (2006) 0.85
High-sensitivity C-reactive protein is a strong risk factor for death after acute ischemic stroke among Chinese. CNS Neurosci Ther (2012) 0.85
Time course of depression and one-year prognosis of patients with stroke in mainland China. CNS Neurosci Ther (2012) 0.85
Prolonged upright posture induces degenerative changes in intervertebral discs in rat lumbar spine. Spine (Phila Pa 1976) (2008) 0.84
PrP(Sc) of scrapie 263K propagates efficiently in spleen and muscle tissues with protein misfolding cyclic amplification. Virus Res (2009) 0.84
RTN/Nogo in forming Alzheimer's neuritic plaques. Neurosci Biobehav Rev (2010) 0.84
The preliminary study of 18F-FLT micro-PET/CT in predicting radiosensitivity of human nasopharyngeal carcinoma xenografts. Ann Nucl Med (2014) 0.84
Classifying Ischemic Stroke, from TOAST to CISS. CNS Neurosci Ther (2012) 0.83
Prolonged upright posture induces calcified hypertrophy in the cartilage end plate in rat lumbar spine. Spine (Phila Pa 1976) (2011) 0.83
The optimal duration of progesterone supplementation in pregnant women after IVF/ICSI: a meta-analysis. Reprod Biol Endocrinol (2012) 0.83
Protein disulfide isomerase regulates endoplasmic reticulum stress and the apoptotic process during prion infection and PrP mutant-induced cytotoxicity. PLoS One (2012) 0.83
[Gel electrophoresis analysis on plasma differential protein in patients with unstable angina of blood-stasis pattern]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2010) 0.83
Regional homogeneity of resting-state brain abnormalities in bipolar and unipolar depression. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.83
Runx1 is critical for PTH-induced onset of mesenchymal progenitor cell chondrogenic differentiation. PLoS One (2013) 0.83
Molecular interaction of TPPP with PrP antagonized the CytoPrP-induced disruption of microtubule structures and cytotoxicity. PLoS One (2011) 0.83
Clinical data mining of phenotypic network in angina pectoris of coronary heart disease. Evid Based Complement Alternat Med (2012) 0.83
Age differences in clinical characteristics, health care, and outcomes after ischemic stroke in China. CNS Neurosci Ther (2012) 0.83
Isolation and characterization of a Pti1 homologue from soybean. J Exp Bot (2003) 0.83
Muscone protects vertebral end-plate degeneration by antiinflammatory property. Clin Orthop Relat Res (2009) 0.83
Consensus statement on the use of intravenous recombinant tissue plasminogen activator to treat acute ischemic stroke by the Chinese Stroke Therapy Expert Panel. CNS Neurosci Ther (2013) 0.82